Abstract:
:Renal lithium clearance, tissue lithium levels, serum lithium concentration, and body temperature were determined in rats given lithium alone or combined with haloperidol (0.5-1 mg/kg). A slight increase in serum lithium concentration occurred in one of the three groups given lithium plus haloperidol. Haloperidol failed to affect renal lithium clearance, tissue lithium levels and body temperature. The data do not support the hypothesis that haloperidol exerts an action on lithium pharmacokinetics.
journal_name
Pharmacologyjournal_title
Pharmacologyauthors
Smith DF,Shimizu M,Schou Mdoi
10.1159/000136708subject
Has Abstractpub_date
1977-01-01 00:00:00pages
337-40issue
4eissn
0031-7012issn
1423-0313journal_volume
15pub_type
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