Cost-effectiveness of pneumococcal conjugate vaccination in immunocompromised adults.

abstract：:Hepatitis B surface antigen (HBsAg) was detected in 3.3% of 7162 pregnant Tunisian women tested and HBeAg in 9.6% of the HBsAg-positive mothers. Family members of 46 of these HBsAg-positive mothers (33 husbands and 61 children aged 1-6 years) were investigated for the presence of HBV markers. HBsAg was detected in 21%...

journal_title：Vaccine

authors： Coursaget P,Gharbi Y,Khrouf N,Depril N,Boukhris N,Fritzell B,Kastally R

更新日期：1994-01-01 00:00:00

abstract：:Influenza is a zoonotic disease caused by a constantly varying RNA virus resulting in a need for continuous surveillance to update human vaccines. Our knowledge indicates that the intermittent pandemics of influenza originate from influenza viruses or gene segments from influenza viruses in lower animals and birds. Th...

journal_title：Vaccine

authors： Webster RG

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:Invasive meningococcal disease has a high burden in young children, particularly during infancy. We investigated the immunogenicity and safety of a quadrivalent meningococcal conjugated vaccine (MenACWY-TT) co-administered with routine vaccines in healthy infants. METHODS:In this phase IIIb study (NCT013408...

journal_title：Vaccine

authors： Dbaibo G,Tinoco Favila JC,Traskine M,Jastorff A,Van der Wielen M

更新日期：2018-06-27 00:00:00

abstract：:This study aimed to evaluate the durability of the immunogenicity of MVA85A beyond infancy. Participants in an immunogenicity study of MVA85A administered at age of 4 months had additional evaluation 14 months after initial vaccination for IFN-γ ELISPOT responses to Ag85A peptide and ESAT6/CFP-10 and tuberculin skin t...

journal_title：Vaccine

authors： Odutola AA,Owolabi OA,Owiafe PK,McShane H,Ota MO

更新日期：2012-08-17 00:00:00

abstract：BACKGROUND:Several vaccines are recommended in HIV-infected patients due to an increased risk of vaccine-preventable infections, severe forms of the disease, or shared transmission routes. Few data are available regarding vaccination coverage and its determinants in this population. METHODS:A cross-sectional study was...

journal_title：Vaccine

authors： Valour F,Cotte L,Voirin N,Godinot M,Ader F,Ferry T,Vanhems P,Chidiac C

更新日期：2014-07-31 00:00:00

abstract：:NetB (necrotic enteritis toxin B) is a recently identified β-pore-forming toxin produced by Clostridium perfringens. This toxin has been shown to play a major role in avian necrotic enteritis. In recent years, a dramatic increase in necrotic enteritis has been observed, especially in countries where the use of antimic...

journal_title：Vaccine

authors： Fernandes da Costa SP,Mot D,Bokori-Brown M,Savva CG,Basak AK,Van Immerseel F,Titball RW

更新日期：2013-08-20 00:00:00

abstract：:The currently used live-attenuated measles vaccine is very effective although maternal antibody prevents its administration prior to 6 months of age. We are investigating the ability of a DNA vaccine encoding the measles viral hemagglutinin, fusion and nucleoprotein to protect newborn infants from measles. Here, we sh...

journal_title：Vaccine

authors： Premenko-Lanier M,Rota P,Rhodes G,Bellini W,McChesney M

更新日期：2004-01-26 00:00:00

abstract：:In a 12-month cohort follow-up study of 2435 children vaccinated in 2007 by Statens Serum Institute BCG strain (BCG SSI, 17.8% had an adverse event (AE): erythema 12.4%, induration 12.2%, abscesses 2.5%, ulceration 0.9%, lymphadenitis 0.1%. The factors associated with a lower risk of AE were: age at vaccination <1 yea...

journal_title：Vaccine

authors： Dommergues MA,de La Rocque F,Guy C,Lécuyer A,Jacquet A,Guérin N,Fagot JP,Boucherat M,d'Athis P,Cohen R

更新日期：2009-11-23 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) often fail to produce protective antibodies to hepatitis B virus (HBV) surface antigen after vaccination. Diabetes mellitus (DM) is the most common cause of CKD; however it is not clear whether it affects immunological response to HBV vaccine in these patients. AIM...

journal_title：Vaccine

authors： Alavian SM,Tabatabaei SV

更新日期：2010-05-14 00:00:00

abstract：BACKGROUND:The recent Ebola outbreak in West Africa led to the use of a variety of different platform technologies for assaying antibodies because of the difficulties of handling the live virus. The same types of method could be applied rapidly to other infections when they emerge. There is a need to compare quantitati...

journal_title：Vaccine

authors： Wilkinson DE,Page M,Mattiuzzo G,Hassall M,Dougall T,Rigsby P,Stone L,Minor P

更新日期：2017-03-01 00:00:00

abstract：:The incidence of Lyme disease has continued to rise despite attempts to control its spread. Vaccination of zoonotic reservoirs of human pathogens has been successfully used to decrease the incidence of rabies in raccoons and foxes. We have previously reported on the efficacy of a vaccinia virus vectored vaccine to red...

journal_title：Vaccine

authors： Kern A,Zhou CW,Jia F,Xu Q,Hu LT

更新日期：2016-08-31 00:00:00

abstract：:The objective of this study was to evaluate different preparations of avian metapneumovirus (aMPV) subtype C as vaccine challenge in turkeys. Two aMPV isolates and their respective nasal turbinate homogenates after propagation in turkeys were used in the study. Significantly higher clinical sign scores were recorded i...

journal_title：Vaccine

authors： Velayudhan BT,Noll SL,Thachil AJ,Shaw DP,Goyal SM,Halvorson DA,Nagaraja KV

更新日期：2007-02-26 00:00:00

abstract：:Two live recombinant vaccines (Flc9 and Flc11) against classical swine fever (CSF) were evaluated for their capacity to reduce transmission of virulent CSF virus (CSFV) among vaccinated pigs. In Flc9 the 5' terminal half of the E2 gene of the C-strain, a CSFV vaccine strain, was exchanged with the homologous gene of t...

journal_title：Vaccine

authors： de Smit AJ,Bouma A,van Gennip HG,de Kluijver EP,Moormann RJ

更新日期：2001-01-08 00:00:00

abstract：:An effective malaria vaccine remains a global health priority. Recombinant adenoviruses are a promising vaccine platform, and Plasmodium falciparum apical membrane antigen 1 (AMA1) and merozoite surface protein 1-42 (MSP1(42)) are leading blood stage vaccine candidates. We evaluated the importance of surface antigen l...

journal_title：Vaccine

authors： Bruder JT,Stefaniak ME,Patterson NB,Chen P,Konovalova S,Limbach K,Campo JJ,Ettyreddy D,Li S,Dubovsky F,Richie TL,King CR,Long CA,Doolan DL

更新日期：2010-04-19 00:00:00

abstract：:DNA vaccines might offer an alternative to the live smallpox vaccine in providing protective efficacy in an orthopoxvirus (OPV) lethal respiratory challenge model. BALB/c mice were immunised with DNA vaccines coding for 10 different single vaccinia virus (VACV) membrane proteins. After an intranasal challenge with the...

journal_title：Vaccine

authors： Pulford DJ,Gates A,Bridge SH,Robinson JH,Ulaeto D

更新日期：2004-09-03 00:00:00

abstract：:We recently reported that administration of low doses of myotoxins at vaccination sites potentiated antigen-specific T-cell immunity induced by genetic cancer vaccines in mice, an effect which was superior to TLR agonists. In the current study, we found unexpectedly that the mechanism of this potent adjuvant effect wa...

journal_title：Vaccine

authors： Qin H,Cha SC,Neelapu SS,Liu C,Wang YH,Wei J,Qin XF,Liu YJ,Kwak LW

更新日期：2010-11-23 00:00:00

abstract：:We evaluated the prevalence and concentration of serum antibodies 18-24 months after primary inoculation with anthrax and botulinum vaccines, and assessed the reactogenicity and immunogenicity of a significantly delayed booster dose of these vaccines. Five hundred and eight male active-duty military personnel received...

journal_title：Vaccine

authors： Pittman PR,Hack D,Mangiafico J,Gibbs P,McKee KT Jr,Friedlander AM,Sjogren MH

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:British Columbia (BC) introduced a school-based HPV vaccine program in September 2008. As part of the HPV vaccine program evaluation, we determined the type-specific HPV prevalence in a population-based sample of women presenting for routine cervical cancer screening in the province. METHODS:From June 2010 ...

journal_title：Vaccine

authors： Ogilvie GS,Cook DA,Taylor DL,Rank C,Kan L,Yu A,Mei W,van Niekerk DJ,Coldman AJ,Krajden M

更新日期：2013-02-04 00:00:00

abstract：:Randomized controlled clinical trials represent the best way to establish the therapeutic or preventive value of medicines. This decade has seen a strong shift in the location of clinical trials from industrialized countries to developing countries, including many in Africa. However, without independent strong regulat...

journal_title：Vaccine

authors： Maïga D,Akanmori BD,Chocarro L

更新日期：2009-12-09 00:00:00

abstract：:Though widely used, the BCG vaccine has had little apparent effect on rates of adult pulmonary tuberculosis. Moreover, the risk of disseminated BCG disease in immunocompromised individuals means that improved TB vaccines ideally need to be able to efficiently prime mycobacterially-naïve individuals as well as boost in...

journal_title：Vaccine

authors： van Dissel JT,Arend SM,Prins C,Bang P,Tingskov PN,Lingnau K,Nouta J,Klein MR,Rosenkrands I,Ottenhoff TH,Kromann I,Doherty TM,Andersen P

更新日期：2010-04-30 00:00:00

abstract：:We compared pertussis surveillance systems of 16 European countries in the period 1998-2002. In twelve out of sixteen countries the system covered the general population. Ten countries relied on WHO case definition for surveillance of pertussis. Eleven countries applied laboratory tests, and eight of them used PCR for...

journal_title：Vaccine

authors： Tozzi AE,Pandolfi E,Celentano LP,Massari M,Salmaso S,Ciofi degli Atti ML,EUVAC-NET Study Group.

更新日期：2007-01-04 00:00:00

abstract：:The 146S particle of the foot and mouth disease virus which is used as a vaccine antigen was found to be relatively stable when stored for prolonged periods at 4 degrees C. However, stored antigens of virus strains of the SAT serotypes but not of a virus strain of the type O serotype became less thermostable at 37 deg...

journal_title：Vaccine

authors： Anderson EC,Doughty WJ,Muthiani A

更新日期：1983-12-01 00:00:00

abstract：:Ebola virus (EBOV) disease (EVD) leads to lethal hemorrhagic fever with a case fatality rate as high as 90%, thus posing a serious global public health concern. However, while several vaccines based on the EBOV glycoprotein have been confirmed to be effective in animal experiments, no licensed vaccines or effective tr...

journal_title：Vaccine

authors： Su QD,He SH,Yi Y,Qiu F,Lu XX,Jia ZY,Meng QL,Fan XT,Tian RG,Audet J,Qiu XG,Bi SL

更新日期：2018-10-01 00:00:00

abstract：:Here, monophosphoryl lipid A (MPLA) and aluminum salt (Alum) were introduced into a hyaluronic acid (HA)-based combination vaccine adjuvant for hepatitis B vaccine (HBV). Although Alum is a well-known hepatitis B vaccine adjuvant that induces an enhanced humoral immune response, it cannot induce the cellular immune re...

journal_title：Vaccine

authors： Moon SH,Shin EC,Noh YW,Lim YT

更新日期：2015-09-11 00:00:00

abstract：:Viral vectors are promising vaccine candidates for eliciting suitable Ag-specific immune response. Since Mycobacterium tuberculosis (Mtb) normally enters hosts via the mucosal surface of the lung, the best defense against Mtb is mucosal vaccines that are capable of inducing both systemic and mucosal immunity. Although...

journal_title：Vaccine

authors： Watanabe K,Matsubara A,Kawano M,Mizuno S,Okamura T,Tsujimura Y,Inada H,Nosaka T,Matsuo K,Yasutomi Y

更新日期：2014-03-26 00:00:00

abstract：:A new strategy for designing synthetic vaccines is presented. In this approach synthetic peptides are conformationally restricted by replacing putative hydrogen bonds with covalent mimics. The chemistry for substituting a hydrazone-ethane link (N-N = CH-CH2-CH2) for an (i + 4)----i hydrogen bond in a pentapeptide with...

journal_title：Vaccine

authors： Satterthwait AC,Arrhenius T,Hagopian RA,Zavala F,Nussenzweig V,Lerner RA

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Vaccination coverage is the usual metrics to evaluate the immunization programs performance. For the 10-valent pneumococcal conjugate (PCV10) vaccine, measuring the delay of vaccination is also important, particularly as younger children are at increased risk of disease. Routinely collected administrative da...

journal_title：Vaccine

authors： Sartori AL,Minamisava R,Afonso ET,Policena GM,Pessoni GC,Bierrenbach AL,Andrade AL

更新日期：2017-02-15 00:00:00

abstract：:A large, randomized, placebo-controlled clinical trial in Italy on two three-component pertussis vaccines, given as DTaP in infancy, one manufactured by SmithKline and Beecham (SB) and one by Chiron Biocine (CB), found each vaccine to be 84% efficacious through the average age of 24 months. The cohort of children enro...

journal_title：Vaccine

authors： Salmaso S,Mastrantonio P,Wassilak SG,Giuliano M,Anemona A,Giammanco A,Tozzi AE,Ciofi degli Atti ML,Greco D

更新日期：1998-08-01 00:00:00

abstract：:A choice-format, conjoint-analysis survey was developed and fielded to estimate how features of human papillomavirus (HPV) vaccines affect mothers' perceived benefit and stated vaccine uptake for daughters. Data were collected from a national sample of 307 U.S. mothers of girls aged 13-17 years who had not yet receive...

journal_title：Vaccine

authors： Brown DS,Johnson FR,Poulos C,Messonnier ML

更新日期：2010-02-17 00:00:00

abstract：:DNA immunization with HIV envelope plasmids induce only moderate levels of specific antibodies which may in part be due to limitations in expression influenced by a species-specific and biased HIV codon usage. We compared antibody levels, Th1/Th2 type and CTL responses induced by synthetic genes encoding membrane boun...

journal_title：Vaccine

authors： Vinner L,Nielsen HV,Bryder K,Corbet S,Nielsen C,Fomsgaard A

更新日期：1999-04-23 00:00:00