Timeliness and risk factors associated with delay for pneumococcal conjugate 10-valent routine immunization in Brazilian children.

abstract：:To evaluate the immunogenicity of 23-valent pneumococcal polysaccharide vaccine in 52 nursing homes residents aged > or = 60 years, IgG antibodies to serotypes 1, 5, 6B, and 8 were measured by ELISA and compared before, and 1 and 12 months following vaccination. A significant immunological response for all serotypes w...

journal_title：Vaccine

authors： Brandão AP,de Oliveira TC,de Cunto Brandileone MC,Gonçalves JE,Yara TI,Simonsen V

更新日期：2004-12-21 00:00:00

abstract：:The Vaccine Adverse Event Reporting System (VAERS) is the US passive surveillance system monitoring vaccine safety. A major limitation of VAERS is the lack of denominator data (number of doses of administered vaccine), an element necessary for calculating reporting rates. Empirical Bayesian data mining, a data analysi...

journal_title：Vaccine

authors： Niu MT,Erwin DE,Braun MM

更新日期：2001-09-14 00:00:00

abstract：:The objectives of this research were to evaluate the risk of prolonged testicular infection as a consequence of vaccination of peri-pubertal bulls with a modified-live, noncytopathic strain of BVDV and to assess vaccine efficacy in preventing prolonged testicular infections after a subsequent acute infection. Seronega...

journal_title：Vaccine

authors： Givens MD,Riddell KP,Walz PH,Rhoades J,Harland R,Zhang Y,Galik PK,Brodersen BW,Cochran AM,Brock KV,Carson RL,Stringfellow DA

更新日期：2007-01-15 00:00:00

abstract：:We describe here two very potent adjuvant systems which are thought to work directly on antigen specific lymphocytes, thus by-passing the normal route for adjuvants, which is to activate antigen presenting cells (APCs) inducing release of inflammatory cytokines with resultant side effects of local and systemic reactog...

journal_title：Vaccine

authors： Barr T,Carlring J,Hatzifoti C,Heath AW

更新日期：2006-04-12 00:00:00

abstract：:The aim of the study was to analyze the impact of MenBvac, an outer membrane vesicle (OMV) vaccine against P1.7,16 strains, on meningococcal carriage. During a B:14:P1.7,16/ST-32 outbreak in Normandy (France), children aged 1-7 years were randomly selected to participate in the study. Among the 1082 volunteers, there ...

journal_title：Vaccine

authors： Delbos V,Lemée L,Bénichou J,Berthelot G,Deghmane AE,Leroy JP,Houivet E,Hong E,Taha MK,Caron F,B14 STOP study group.

更新日期：2013-09-13 00:00:00

abstract：:The physico-chemical characterization of NadADelta(351-405), a recombinant protein discovered by reverse vaccinology, component of a candidate vaccine against Neisseria meningitidis serotype B is presented. Analytical methods like mass spectrometry, electrophoresis, optical spectroscopy and SEC-MALLS have been applied...

journal_title：Vaccine

authors： Magagnoli C,Bardotti A,De Conciliis G,Galasso R,Tomei M,Campa C,Pennatini C,Cerchioni M,Fabbri B,Giannini S,Mattioli GL,Biolchi A,D'Ascenzi S,Helling F

更新日期：2009-03-26 00:00:00

abstract：:Insoluble, pure protein particles could be advantageous as single-entity vaccines or as carriers for small peptide epitopes. Dense gas anti-solvent precipitation was employed to produce pure protein particles which were found to be insoluble in water. As particulate and multimerized antigens are more immunogenic and h...

journal_title：Vaccine

authors： White PJ,Anastasopoulos F,Church JE,Kuo CY,Boyd BJ,Hickey PL,Tu LS,Burns P,Lew AM,Heath WR,Davey GM,Pouton CW

更新日期：2008-12-09 00:00:00

abstract：:Effort has been made to identify protective antigens in order to develop a recombinant vaccine against leptospirosis. Several attempts failed to conclusively demonstrate efficacy of vaccine candidates due to the lack of an appropriate model of lethal leptospirosis. The purposes of our study were: (i) to test the virul...

journal_title：Vaccine

authors： Silva EF,Santos CS,Athanazio DA,Seyffert N,Seixas FK,Cerqueira GM,Fagundes MQ,Brod CS,Reis MG,Dellagostin OA,Ko AI

更新日期：2008-07-23 00:00:00

abstract：INTRODUCTION:Endemic measles persists in China, despite >95% reported coverage of two measles-containing vaccine doses and nationwide campaign that vaccinated more than 100 million children in 2010. In 2011, almost half of the 9943 measles cases in China occurred in children eligible for measles vaccination. We conduct...

journal_title：Vaccine

authors： Hao L,Ma C,Wannemuehler KA,Su Q,An Z,Cairns L,Quick L,Rodewald L,Liu Y,He H,Xu Q,Ma Y,Yu W,Zhang N,Li L,Wang N,Luo H,Wang H,Gregory CJ

更新日期：2016-12-12 00:00:00

abstract：:H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing the need for a broadly protective influenza vaccine. Here, we constructed BV-Dual-3M2e-LTB, a recombinant baculo...

journal_title：Vaccine

authors： Zhang J,Fan HY,Zhang Z,Zhang J,Zhang J,Huang JN,Ye Y,Liao M

更新日期：2016-01-27 00:00:00

abstract：:Antibodies have the potential to be therapeutic reagents for malaria. Here we describe the production of a novel phage antibody display library against the C-terminal 19kDa region of the Plasmodium yoelii YM merozoite surface protein-1 (MSP1(19)). In vivo studies against homologous lethal malaria challenge show an ant...

journal_title：Vaccine

authors： Vukovic P,Chen K,Qin Liu X,Foley M,Boyd A,Kaslow D,Good MF

更新日期：2002-06-21 00:00:00

abstract：:Our current knowledge allows the generation of transgenic plants that efficiently produce heterologous proteins from plant, bacterial, fungal or animal origin. Among all types of recombinant proteins, antibodies are particularly attractive because of their ability to specifically recognize and bind virtually any type ...

journal_title：Vaccine

authors： Peeters K,De Wilde C,De Jaeger G,Angenon G,Depicker A

更新日期：2001-03-21 00:00:00

abstract：:Active and passive immunotherapy targeting amyloid-β (Aβ) may be the most promising strategy to prevent or treat Alzheimer's disease (AD). Previously, immunization with the recombinant 6Aβ15-T antigen generated robust anti-Aβ serum antibodies that strongly recognized Aβ42 oligomers in different mice, markedly reduced ...

journal_title：Vaccine

authors： Wang HC,Yu YZ,Liu S,Zhao M,Xu Q

更新日期：2016-04-04 00:00:00

abstract：:A family of parasite antigens known as Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is believed to play an important role in the binding of infected erythrocytes to host receptors in the micro-vasculature. Available data advocates the existence of a subset of very adhesive (rosetting, auto-agglutinati...

journal_title：Vaccine

authors： Chen Q,Pettersson F,Vogt AM,Schmidt B,Ahuja S,Liljeström P,Wahlgren M

更新日期：2004-07-29 00:00:00

abstract：:Persistence of antibodies 4 years after vaccination with measles, mumps and rubella (MMR) vaccine from three different manufacturers was compared in 475 children who received a single injection of vaccine when aged 12-18 months. Antibodies to measles and mumps were measured using a plaque reduction neutralisation assa...

journal_title：Vaccine

authors： Miller E,Hill A,Morgan-Capner P,Forsey T,Rush M

更新日期：1995-06-01 00:00:00

abstract：:The development of single-dose vaccines, mainly those administered during childhood, which would effectively protect against certain diseases, would be a very important advance towards better immunization coverage and protection against the respective pathogens. Biodegradable polymeric microspheres which are 'programm...

journal_title：Vaccine

authors： Aguado MT

更新日期：1993-01-01 00:00:00

abstract：:In July of 2014, a symposium entitled "Enhancing Vaccine Immunity and Value" was held in Siena, Italy. The focus of the symposium was on how to best meet the challenge of developing and implementing vaccines for future disease targets. Vaccination has been responsible for averting estimated 3 billion cases of disease ...

journal_title：Vaccine

authors： Rappuoli R

更新日期：2015-06-08 00:00:00

abstract：INTRODUCTION:One of the goals of the Global Measles and Rubella Strategic Plan is the reduction in global measles mortality, with high measles vaccination coverage as one of its core components. While measles mortality has been reduced more than 79%, the disease remains a major cause of childhood vaccine preventable di...

journal_title：Vaccine

authors： Doshi RH,Eckhoff P,Cheng A,Hoff NA,Mukadi P,Shidi C,Gerber S,Wemakoy EO,Muyembe-Tafum JJ,Kominski GF,Rimoin AW

更新日期：2017-10-27 00:00:00

abstract：:Cholera toxin B subunit (CTB) and Escherichia coli heat-labile toxin (LTB) (2 micrograms), each supplemented with a trace amount of cholera toxin (CT) (0.02-20 ng), were examined for the adjuvant effect on antibody (Ab) response against influenza inactivated HA (haemagglutinin) vaccine in Balb/c mice. Each mouse recei...

journal_title：Vaccine

authors： Tamura S,Yamanaka A,Shimohara M,Tomita T,Komase K,Tsuda Y,Suzuki Y,Nagamine T,Kawahara K,Danbara H

更新日期：1994-04-01 00:00:00

abstract：:Routine administration of the quadrivalent human papillomavirus (HPV) vaccine has been recommended for 11-12-year-old males since 2011, but coverage remains low. In a U.S. national sample of parents of 11-17-year-old males (n=779), 78.6% of parents reported their sons had not received the HPV vaccine. The most common ...

journal_title：Vaccine

authors： Donahue KL,Stupiansky NW,Alexander AB,Zimet GD

更新日期：2014-06-30 00:00:00

abstract：:The objectives of this study were to evaluate the effects of a therapeutic vaccine intervention with a modified-live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine on the dynamics of a heterologous viral infection in a population of pigs, and to determine the clinical and virological response of p...

journal_title：Vaccine

authors： Cano JP,Dee SA,Murtaugh MP,Pijoan C

更新日期：2007-05-30 00:00:00

abstract：:Group A rotavirus (RVA) is a major cause of diarrhea and diarrhea-related mortality in foals in parts of the world. In addition to careful horse farm management, vaccination is the only known alternative to reduce the RVA associated disease burden on horse farms. The precise evaluation of vaccine effectiveness against...

journal_title：Vaccine

authors： Papp H,Matthijnssens J,Martella V,Ciarlet M,Bányai K

更新日期：2013-11-19 00:00:00

abstract：:Vaccines have drastically reduced the mortality and morbidity of many diseases. However, vaccines have historically been developed empirically, and recent development of vaccines against current pandemics such as HIV and malaria has been met with difficulty. The advent of high-throughput technologies, coupled with sys...

journal_title：Vaccine

authors： Hagan T,Nakaya HI,Subramaniam S,Pulendran B

更新日期：2015-09-29 00:00:00

abstract：:An immuno-informatics study was conducted to determine possible pre-existing T cellular immunity to the recently emerged swine-origin triple reassortant H3N2 variant (S-OtrH3N2v-2011) which acquired the matrix gene of influenza A (H1N1)pdm09. Given the genetic origin of S-OtrH3N2v-2011, our study focused on the hemagg...

journal_title：Vaccine

authors： Duvvuri VR,Marchand-Austin A,Eshaghi A,Patel SN,Low DE,Gubbay JB

更新日期：2012-09-14 00:00:00

abstract：:During a pertussis epidemic in 2011-2012 the Western Australian (WA) Department of Health implemented a 'cocooning' programme, offering free pertussis-containing vaccine (dTpa) to new parents. We assessed the impact of vaccinating parents with dTpa on the incidence of pertussis infection in newborns. Births in WA duri...

journal_title：Vaccine

authors： Carcione D,Regan AK,Tracey L,Mak DB,Gibbs R,Dowse GK,Bulsara M,Effler PV

更新日期：2015-10-13 00:00:00

abstract：:Plasmodium vivax is responsible for an approximate 35 million yearly human cases of malaria. Unfortunately, due to the low mortality rate associated with it and the difficulties of continuously in vitro culturing of this parasite, vaccine development against this human malaria has been largely neglected. In here, the ...

journal_title：Vaccine

authors： de Oliveira CI,Wunderlich G,Levitus G,Soares IS,Rodrigues MM,Tsuji M,del Portillo HA

更新日期：1999-08-06 00:00:00

abstract：:This study compared responses of bison calves to 10(10)CFU of Brucella abortus strain RB51 (SRB51) delivered by parenteral or ballistic methods. Two types of biobullet payloads were evaluated; compacted SRB51 pellets or SRB51 encapsulated in photopolymerized poly(ethylene glycol) hydrogels. Bison were vaccinated with ...

journal_title：Vaccine

authors： Olsen SC,Christie RJ,Grainger DW,Stoffregen WS

更新日期：2006-02-27 00:00:00

abstract：:The first population-based survey to determine predictors of influenza vaccination among children in a major metropolitan city with access to publicly funded health care and a universal influenza immunization program (UIIP). Previously collected demographic and health related data from 5619 school children aged 5-9 in...

journal_title：Vaccine

authors： Foty RG,Guttmann A,Kwong JC,Maaten S,Manuel D,Stieb DM,Dell SD

更新日期：2010-09-07 00:00:00

abstract：:Since the development of the first vaccine over 200 years ago, vaccines have saved millions of lives and have become the most cost-effective modern medical intervention. However, over 70 years ago, Freund recognized that the effectiveness of the vaccine-induced immune responses could be vastly improved via the co-deli...

journal_title：Vaccine

authors： Alter G,Sekaly RP

更新日期：2015-06-08 00:00:00

abstract：:Many influenza vaccines targeted to hemagglutinin (HA) show efficient immunogenicity for protecting subjects against influenza virus infection. Major antigenic changes to HA molecules can help influenza virus to develop resistance against HA-targeted vaccines. DNA vaccines encoding conserved antigens protect animals a...

journal_title：Vaccine

authors： Ohba K,Yoshida S,Zahidunnabi Dewan M,Shimura H,Sakamaki N,Takeshita F,Yamamoto N,Okuda K

更新日期：2007-05-22 00:00:00