Diagnostic significance and possible pitfalls of nuclear grooves in extrathyroid cytology.

Abstract:

:The diagnostic significance of grooved nuclei in the cytology of extrathyroid lesions is not well-described in the literature. Isolated cases of metastatic adult granulosa cell tumor, reactive mesothelial hyperplasia, Langerhans' cell histiocytosis, recurrent renal cell carcinoma, and round cell liposarcoma were reviewed, and their cytologic features were discussed. While nuclear grooving can be present to a different extent in all these conditions, the significance of this feature in diagnostic cytology varies. The integration of clinical information, radiologic findings, different morphologic features, and immunohistochemistry is necessary before a final conclusion is reached.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Ng WK,Collins RJ

doi

10.1002/(sici)1097-0339(199701)16:1<57::aid-dc14>3

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

57-64

issue

1

eissn

8755-1039

issn

1097-0339

pii

10.1002/(SICI)1097-0339(199701)16:1<57::AID-DC14>3

journal_volume

16

pub_type

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