Abstract:
:Giant cell glioblastoma is a histological variant of glioblastoma that accounts for less than 1% of intracranial tumors and to 5% of glioblastoma. They occur at any age and are likely to affect the younger as well the older age group unlike the conventional glioblastoma multiforme (GBM). They are often located subcortically in the temporal and parietal lobes. Cytological descriptions of giant cell glioblastoma are extremely rare. We describe squash cytomorphology of giant cell glioblastoma of left posterior frontal region in 35-year-old male. The squash smears were moderately cellular displaying malignant astrocytic tumor cells disposed in cohesive clusters and dispersed population on a necrotic background. Most striking feature was numerous multinucleated giant cells. We also discuss the differential diagnosis in light of relevant literature.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Jaiswal S,Vij M,Jaiswal AK,Srivastava AK,Behari S,Pandey Rdoi
10.1002/dc.21648subject
Has Abstractpub_date
2012-05-01 00:00:00pages
440-3issue
5eissn
8755-1039issn
1097-0339journal_volume
40pub_type
杂志文章,评审abstract::The use of ultrasound-guided fine-needle aspiration (FNA) biopsy for nonpalpable breast lesions varies considerably. This retrospective study stresses the role of breast FNA in evaluating sonographically suspicious nonpalpable breast masses using a probabilistic reporting system. One hundred and eight consecutive ultr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20068
更新日期:2004-05-01 00:00:00
abstract::To evaluate cytological atypical changes in apparently healthy oral mucosa exposed to smoking, alcohol, hot meals, and peppers using the AgNOR and Papanicolaou methods. A total of 180 individuals were evaluated, of which 60 were smokers, 34 were alcohol users, 52 were habitual peppers and hot meal (exposed) consumers,...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21224
更新日期:2010-07-01 00:00:00
abstract::Metastatic dissemination is the primary cause of death in ovarian cancer (OvCa) patients, and dissemination to pleural and peritoneal effusions is a common clinical event. Effusion samples were collected from 15 OvCa patients. Twenty-six samples were collected prospectively, two were archival, and eight were taken fro...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20279
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Bile duct brushing (BDB) cytology, for the characterization of bile duct strictures, can be challenging to interpret when associated with a stent. Our study aims to identify the cytologic criteria for the diagnosis of adenocarcinoma in BDBs in the presence of a stent. METHODS:A database search (January 2010...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24052
更新日期:2018-10-01 00:00:00
abstract::Synovial sarcomas (SS) of the head and neck region are extremely rare and arise in only 5% of cases. We present a case of secondary SS of the thyroid originally diagnosed as medullary carcinoma on fine needle aspiration (FNA). A 41-year-old man presented with several weeks of dysphonia and a left thyroid mass. FNA of ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23327
更新日期:2015-11-01 00:00:00
abstract::Asbestos pollution is a global problem. Asbestos exposure induced mesothelioma does not require an 'occupational' type of exposure. Bystander exposures may result in earlier age of disease onset and more aggressive disease progression as described in the following 3 case reports. ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20766
更新日期:2007-12-01 00:00:00
abstract::Needle tract seeding refers to implantation of tumor cells by contamination when instruments like biopsy needles are used to examine, excise or ablate a tumor. Implantation along needle tract may lead to change of stage of the tumor, converting a resectable tumor into an inoperable one. In this paper we have reviewed ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23137
更新日期:2014-07-01 00:00:00
abstract::Most of the available data in the literature describe the cytomorphological features of exfoliated malignant epithelial cells in urine. There are no established diagnostic features that characterize the morphology of exfoliated malignant mesenchymal tumor in urine. Here we highlight the problems in the diagnosis of th...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20053
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Ubiquilin 2 (UBQLN2), an ubiquitin-related protein, is strongly expressed in urothelial carcinoma cells, in contrast to no or less expression in non-neoplastic cells; it protects cancer cells from reactive oxygen species (ROS)-induced cytotoxicity. In this study, we investigated whether UBQLN2 immunostaining...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23332
更新日期:2016-01-01 00:00:00
abstract::Myoepithelial cells are an important component of salivary gland tumors and are partly responsible from the diverse histology of them. In this study, we focus on the myoepithelial cell differentiation by using cytological morphology in a various types of salivary gland tumors especially with regard to their contributi...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21544
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Homeobox transcription factors have demonstrated utility in diagnosing neuroendocrine tumors. Orthopedia homeobox protein (OTP) has a well-defined role in embryonic neurodevelopment and has also been described as a prognostic marker in lung neuroendocrine tumors (NET). Additionally, NK6 homeobox-1 (NKX6.1) h...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24088
更新日期:2018-12-01 00:00:00
abstract::A 50-yr-old man presented with dyspnea. On chest X-ray, multiple pulmonary nodules were observed. Fine-needle aspiration biopsy (FNAB) showed tridimensional aggregates of atypical round epithelial cells, containing numerous cytoplasmic granules. The tissue fragment confirmed the presence of an epithelial tumor compose...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199907)21:1<51::aid-dc14>3
更新日期:1999-07-01 00:00:00
abstract::Lymphomas presenting in effusions could either be primary or secondary, with very limited data from Taiwan. METHODS:We retrospectively reviewed effusion lymphomas from our archives in a tertiary center from July 2011 to June 2019. RESULTS:We identified 59 specimens from 43 patients, including 7 cases with primary ef...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24626
更新日期:2021-02-01 00:00:00
abstract::Over an 8-yr period at the Houston Veterans Hospital, 731 endoscopic gastric salvage cytologies were performed in 671 patients, with surgical biopsy also done in 660. Seventy-six patients subsequently had tissue biopsy-proven or resection-proven malignancies. Salvage cytology had a sensitivity of 91% and a specificity...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840060102
更新日期:1990-01-01 00:00:00
abstract::Basal cell adenocarcinoma (BCAC) of salivary glands is uncommon low-grade malignancy. Only 19 cases of preoperative cytology were reported up to date. We present here a new case of BCAC arising in the minor salivary gland. Tumor was composed of clustered or isolated roundish, dark cells with small and regular nuclei. ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23919
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:This study aims to assess in our institutional experience the accuracy of fine needle aspiration cytology (FNAC) in the diagnosis of salivary gland masses (SGM) according to the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) and to an in-house system. METHODS:The study included 189 FNACs c...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24682
更新日期:2020-12-21 00:00:00
abstract::Residual material from liquid-based pap (LBP) test has been used for molecular testing of Human Papilloma Virus (HR HPV) DNA. LBP test specimens (1,025) were evaluated to determine how often residual material was insufficient to perform microbiological testing. The specimens were tested for Chlamydia trachomatis and N...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20325
更新日期:2005-09-01 00:00:00
abstract::The evaluation of invasion in urothelial carcinomas of the urinary bladder cannot be determined on cytology and can be particularly challenging in biopsy cases with limited sampling. Recent studies of bladder resection specimens suggest that fascin overexpression may be a marker of aggressive urothelial carcinomas and...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21429
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) is important for the differential diagnosis of solid pancreatic lesions. Sample adequacy is related to the number of needle passes, and European guidelines recommend three to four needle passes with a standard EUS-FNA needle. We aimed to eval...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24669
更新日期:2020-11-21 00:00:00
abstract:UNLABELLED:Fine needle aspiration (FNA) in conjunction with flow cytometry (FC) is a useful technique for non-Hodgkin's lymphoma (NHL) diagnosis. We sought to investigate the effect of storage medium and time to processing on lymph node (LN) FNA viability. Benign LN FNAs were distributed among Roswell Park Memorial Ins...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21780
更新日期:2012-11-01 00:00:00
abstract::Giant-cell tumor (GCT) of bone arising from phalanx of a finger is extremely rare. Rizzoli Orthopedic Institute in their study on 900 treated cases of GCT from 1947-1997 reported only 0.9% incidence of GCT in bones of the hand. There was no case of GCT of the phalanges in that series. We report here a case of GCT of b...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21715
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to clarify the diagnostic significance of the presence of intranuclear inclusions in clear cell carcinoma (CCC). MATERIALS AND METHODS:We analyzed 98 imprint specimens and 53 ascites specimens from 98 ovarian carcinoma cases [28 CCCs, 37 serous carcinomas (SCs), 22 endometrioid carc...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23322
更新日期:2015-11-01 00:00:00
abstract::Strumal carcinoid is a rare ovarian tumor defined as carcinoid associated with struma ovarii. We report here the second cytological case of strumal carcinoid and performed immunocytochemical analysis for the first time. A 68-year-old Japanese female was found to have a solid tumor with small cystic components in the l...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24042
更新日期:2019-03-01 00:00:00
abstract::The largest series, to date, of fine-needle aspiration cytology (FNAC) findings in clear-cell sarcoma of the kidney (CCSK) is presented. All fine-needle aspirates of pediatric renal masses over a 17-yr period were reviewed. Eight out of 119 aspirates from late-stage childhood renal tumors (6.72%) were found to be CCSK...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20317
更新日期:2005-08-01 00:00:00
abstract::The Breast Care Consultation Center (BCCC) is a multidisciplinary center providing, in a single setting, a complete outpatient facility for women who have been diagnosed with or suspected of having breast cancer. A team of specialists are available to provide comprehensive, diagnostic (radiologist, surgeon, and pathol...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199709)17:3<191::aid-dc4>3
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:The difference in expression of sputum cells types between the two main types of chronic obstructive pulmonary disease (COPD) is largely unknown. This study aims to investigate the difference and then wants to depend on sputum cells sorting to direct the treatment of COPD. METHODS:A total of 218 patients wi...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23818
更新日期:2017-12-01 00:00:00
abstract::Malignant renal neoplasms are common solid tumors in pediatric oncology practice. These include the common Wilms' tumor/nephroblastoma and the uncommon neoplasms such as clear-cell sarcoma of the kidney (CCSK), rhabdoid tumor, renal-cell carcinoma, and others. The aim of this study was to describe in detail the cytopa...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20242
更新日期:2005-05-01 00:00:00
abstract::The present study sought possible factors leading to the cytological diagnosis of atypical squamous cells of uncertain significance (ASCUS) in cases of high-grade squamous intraepithelial lesions (HSIL). Based on retrospective histopathological analysis of loop electrical excision procedure (LEEP) products that diagno...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10035
更新日期:2002-01-01 00:00:00
abstract::Genital tract tuberculosis is usually secondary to an extragenital tubercular focus. Cervical tuberculosis, however, is rare accounting for up to 3% of all genital tract diseases. The diagnosis of tuberculosis is usually established on multiple cervical biopsies followed by bacteriological confirmation. There are only...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21082
更新日期:2009-08-01 00:00:00
abstract::This study investigates the potential value of the nuclear matrix protein NMP179 as a marker of abnormal squamous cells in ThinPrep slides. Forty-six cervical scrapes were collected as cell suspensions and ThinPrep slides were prepared. They were double-immunostained for NMP179 and Cytokeratin 18 (CK18), an endocervic...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20061
更新日期:2004-09-01 00:00:00