Abstract:
:The Breast Care Consultation Center (BCCC) is a multidisciplinary center providing, in a single setting, a complete outpatient facility for women who have been diagnosed with or suspected of having breast cancer. A team of specialists are available to provide comprehensive, diagnostic (radiologist, surgeon, and pathologist), therapeutic (surgeon, radiotherapist, and medical oncologist), and support options. The pathologist, as a member of the diagnostic team, evaluates the material obtained or received at the BCCC. These include fine-needle aspirations (FNAs) obtained on-site as well as previously prepared cytohistological specimens. The pathologist renders the diagnosis following examination of the material and consultation with the multidisciplinary team. Thus, this approach is conducive for appropriate and accurate diagnosis where all data are available. In addition, the pathologist discusses the findings of each patient in the multidisciplinary conference. One thousand four hundred eighteen patients were evaluated at Magee-Womens Hospital BCCC from February 1992 through December 1994, during which time 366 FNAs were performed. The accuracy for positive diagnosis was 100%. Six negative cases had cancer on histology; these were due to sampling error (the lesion was missed). A multidisciplinary team is ideal for the evaluation of breast lesions that are suspicious for malignancy as it provides one-stop shopping and same-day diagnosis and therapeutic decisions.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Kanbour-Shakir A,Harris KM,Johnson RR,Kanbour AIdoi
10.1002/(sici)1097-0339(199709)17:3<191::aid-dc4>3subject
Has Abstractpub_date
1997-09-01 00:00:00pages
191-6issue
3eissn
8755-1039issn
1097-0339pii
10.1002/(SICI)1097-0339(199709)17:3<191::AID-DC4>3journal_volume
17pub_type
杂志文章abstract::Polyomavirus BK (BKV) has ebeen identified as the main cause of polyomavirus-associated nephropathy, a major cause of renal allograft failure. Although BKV-associated nephropathy develops in only 2% to 5% of renal transplant recipients, its prognosis when present is very poor, with irreversible graft failure developin...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.21147
更新日期:2009-10-01 00:00:00
abstract::Fine-needle aspiration (FNA) biopsy of the salivary gland is a sensitive and specific diagnostic tool. However, diagnostic problems are sometimes encountered in interpreting some cases, not only in differentiating benign from malignant cases but also in the specific classification of these neoplasms. We report a case ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.20954
更新日期:2009-01-01 00:00:00
abstract::Endometrical cytology sampling using the Endo-pap sampler is an inexpensive, painless, and simple procedure. Tissue microfragments obtained include surface epithelial sheets, gland segments, and stromal cell aggregates. Gland segments are critical for evaluation of the sample. Glands are dilated in hyperplasia and the...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840010104
更新日期:1985-01-01 00:00:00
abstract::The cytologic findings in 13 cases of cervical adenocarcinoma in situ (mean age 33.9 yr) were compared with those in 9 cases of cervical invasive adenocarcinoma (mean age 45.7 yr). All diagnoses were confirmed by biopsy. The major differences found were that a necrotic background (66% invasive vs. 0% in situ) and macr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840120206
更新日期:1995-03-01 00:00:00
abstract::Early and accurate diagnosis of hepatocellular carcinoma in liver nodules using fine-needle aspiration biopsy can still pose difficulties, particularly in cirrhotic nodules containing dysplastic hepatocytes. Loss of architectural clues, which may aid diagnosis, can be overcome by using confocal scanning laser microsco...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/1097-0339(200008)23:2<82::aid-dc3>3.0.co;2
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Despite Aptima assay as the latest US Food Drug Administration (FDA)-approved high-risk human papillomavirus (hrHPV) test has been implemented as an adjunct in cervical cancer screening for years, histological follow-up data remain limited with respect to its performance in women with ASC-US Pap tests and po...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24592
更新日期:2021-01-01 00:00:00
abstract::Adenomatous neuroendocrine tumors of the middle ear (MEANTs) are very rare neoplasms which are composed of both epithelial and neuroendocrine components. They have mostly bland histology and indolent biological behavior, yet they may recur and metastasize. Here we present a case of MEANT with ipsilateral local brain, ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24640
更新日期:2020-10-12 00:00:00
abstract::The authors present a case of cardiac angiosarcoma diagnosed by fine-needle aspiration (FNA) in a 33-year-old male. A percutaneous right atrial mass biopsy was performed via a right internal jugular venous approach and under echocardiographic guidance. FNA showed pleomorphic spindle-shaped cells present singly and in ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20532
更新日期:2007-03-01 00:00:00
abstract::Diffuse large B-cell lymphoma (DLBCL) with fibrillary matrix is an extremely rare variant of non-Hodgkin's lymphoma (NHL) whose pathological features are poorly known. Here, we report on our experience with such a condition arising in a 71-yr-old woman. Our findings not only demonstrate that DLBCL with fibrillary matr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10172
更新日期:2002-10-01 00:00:00
abstract:INTRODUCTION:The incidence of thyroid cancer is increasing which can be attributed in part to improved ultrasonography (US) methods and increased detection of incidental thyroid carcinomas (ITC). We aimed to compare ITC with nonincidental thyroid carcinomas (NITC) in this study. METHODS:Retrospective analyses of 906 i...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24117
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Vaginal fine-needle aspiration (FNA) is infrequently performed to assess palpable lesions. We perform the first multi-institutional study to evaluate this procedure. METHODS:We retrospectively reviewed vaginal FNAs performed at two institutions for the past 27 years. Clinical, cytological and histological d...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23504
更新日期:2016-08-01 00:00:00
abstract::Papillary tumor of the pineal region (PTPR) is a rare neuroepithelial tumor of the pineal region of adults. We herein describe on a 34-year-old female the cytologic features of a PTPR studied using Diff-Quik stain. The patient presented hydrocephalia secondary to a pineal tumor. During surgery an intraoperative pathol...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23560
更新日期:2016-12-01 00:00:00
abstract::Solitary fibrous tumor is a rare lesion of serosal membranes. In a pleural location, it may be confused clinically with a localized mesothelioma or a peripheral lung tumor. A transthoracic needle aspiration can be done to obtain material for a diagnosis in these easily accessible tumors. In the literature, there are o...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199802)18:2<118::aid-dc7>3
更新日期:1998-02-01 00:00:00
abstract::A lipoblastoma is a rare benign tumor of immature white fat, and more than 90% of lipoblastomas occur before the age of 3 years. The diagnosis of a lipoblastoma is mostly dependent on a histopathological examination of a surgically excised specimen. However, an accurate preoperative diagnosis is essential for the plan...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20826
更新日期:2008-07-01 00:00:00
abstract::Metaplastic breast carcinomas (MBCs) are not only uncommon neoplasms but also show a myriad of cytomorphologic patterns in aspiration samples. These tumors comprise less than 5% of breast malignancies and have an uncertain prognosis. In this study, the fine-needle aspiration cytologic features of 14 MBCs with the iden...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199901)20:1<10::aid-dc3>3.
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Ubiquilin 2 (UBQLN2), an ubiquitin-related protein, is strongly expressed in urothelial carcinoma cells, in contrast to no or less expression in non-neoplastic cells; it protects cancer cells from reactive oxygen species (ROS)-induced cytotoxicity. In this study, we investigated whether UBQLN2 immunostaining...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23332
更新日期:2016-01-01 00:00:00
abstract::Neuroglial heterotopias (NGH) are rare congenital head and neck lesions composed of differentiated neuroectodermal tissue and representing developmental heterotopias rather than true neoplasms. The case of a male neonate with respiratory distress and early feeding problems depicting a retropharyngeal space mass which ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21575
更新日期:2011-11-01 00:00:00
abstract::Metaplastic cells with nebular cytoplasmic changes in the cervical smear are classified in the Dutch coding system for cervical screening as KOPAC O8 cells. Since these nebulated cells are already documented by Papanicolaou, we refer to these cells as Papanicolaou's nebular cells. We examined the simultaneous presence...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21523
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Homeobox transcription factors have demonstrated utility in diagnosing neuroendocrine tumors. Orthopedia homeobox protein (OTP) has a well-defined role in embryonic neurodevelopment and has also been described as a prognostic marker in lung neuroendocrine tumors (NET). Additionally, NK6 homeobox-1 (NKX6.1) h...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24088
更新日期:2018-12-01 00:00:00
abstract::The role of fine-needle aspiration cytology (FNAC) in the diagnosis of benign skin lesions has been restricted primarily to the evaluation of bacteriologic and morphologic indices in leprosy. This study was undertaken to evaluate the efficacy of FNAC in the diagnosis and classification of lepromatous lesions. Aspirate...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.1068
更新日期:2001-05-01 00:00:00
abstract::We report three cases of cytomegalovirus (CMV) sialadenitis which presented as parotid gland nodules in patients infected with the human immunodeficiency virus. While CMV is known to widely infect patients with the acquired immunodeficiency syndrome (AIDS), we are aware of only a single report of CMV sialadenitis in a...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840100216
更新日期:1994-01-01 00:00:00
abstract::Synovial sarcoma (SS) is one of the most common soft tissue tumors that typically presents in the extremities of young adults, but may occur at any site and affect children during the first decade. Herein we discuss a 12-yr-old male who complained of left foot pain and plantar mass. A fine-needle aspiration biopsy of ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20566
更新日期:2006-11-01 00:00:00
abstract::Confirmation of human papillomavirus (HPV) as a causative agent for a subset of biologically and clinically distinct squamous cell carcinomas of the head and neck (HNSCC) has resulted in a growing need and expectation for HPV testing of head and neck cancers. At the same time, opportunities to obtain tissue samples fo...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23014
更新日期:2014-01-01 00:00:00
abstract::In this study, we applied artificial neural network (ANN) for the diagnosis of lobular carcinoma in fine-needle aspiration cytology (FNAC) material. We selected a total of 64 cases of histology proven breast lesions consisting of 20 fibroadenomas, 28 infiltrating ductal carcinomas (IDC), and 16 infiltrating lobular ca...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21773
更新日期:2013-02-01 00:00:00
abstract::Precise preoperative diagnosis of three malignant nerve sheath tumors (MNST) was based on their remarkably uniform and highly characteristic cytologic appearance. The differential diagnosis with benign nerve sheath tumors and other spindle cell sarcomas is addressed, and the possibility of achieving confident diagnosi...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840080603
更新日期:1992-01-01 00:00:00
abstract::Although subacute granulomatous thyroiditis (SGT) is usually diagnose clinically, there are other thyroid conditions that must be ruled out. This task is achieved by means of fine-needle aspiration (FNA). In retrospect, the clinical and cytologic findings seen in 36 SGT cases are reassessed with a view to deciding whi...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199703)16:3<214::aid-dc4>3
更新日期:1997-03-01 00:00:00
abstract::Primary pancreatic leiomyosarcomas are rare tumors of the pancreas that are usually diagnosed after resection or by biopsy. One case in the literature has utilized endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology. We report a second case of a primary pancreatic leiomyosarcoma that yielded diagnos...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23540
更新日期:2016-12-01 00:00:00
abstract::Chondroid syringoma is a rare benign skin adnexal tumor of eccrine/apocrine origin affecting commonly the head and neck region. It used to be previously called as mixed tumor of skin because of the presence of both the epithelial and mesenchymal components. There are only few case reports describing the fine needle as...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21159
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:Hürthle cell (HC) metaplasia is an important feature of chronic lymphocytic (Hashimoto) thyroiditis (HT). However, it is rarely observed in juvenile form HT. In a study based on fine needle aspiration cytology, the cytomorphological difference between pediatric HT and its adult form was studied, with special...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.24140
更新日期:2019-05-01 00:00:00
abstract::Pulmonary cryptococcoma is a life threatening mycosis and is an unusual disease for immunocompetent individuals. Herein we report a case of large pulmonary cryptococcoma associated with cryptococcal meningitis, presenting radiologically as a lung mass in right upper lobe, in a previously healthy, HIV negative, immunoc...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21345
更新日期:2010-12-01 00:00:00