Pleomorphic adenoma with predominant plasmocytoid myoepithelial cells: a diagnostic pitfall in aspiration cytology. Case report and review of the literature.

Abstract:

:Fine-needle aspiration (FNA) biopsy of the salivary gland is a sensitive and specific diagnostic tool. However, diagnostic problems are sometimes encountered in interpreting some cases, not only in differentiating benign from malignant cases but also in the specific classification of these neoplasms. We report a case of a pleomorphic adenoma with predominant plasmocytoid myoepithelial cells arising in minor salivary glands from the hard palate in a 78-year-old patient, which was falsely diagnosed as a carcinoma on liquid-based cytology (ThinPrep (TP)). The differential diagnosis of salivary gland tumors with predominant myoepithelial cells on FNA biopsy is discussed.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Pusztaszeri M,Braunschweig R,Mihaescu A

doi

10.1002/dc.20954

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

56-60

issue

1

eissn

8755-1039

issn

1097-0339

journal_volume

37

pub_type

杂志文章,评审
  • Cerebrospinal Fluid Cytological Diagnosis in Multiple Myeloma With Leptomeningeal Involvement: A Report of Two Cases.

    abstract::Multiple myeloma (MM) with central nervous system (CNS) infiltration is uncommon and the diagnosis is more complicated than that of MM. Here we report two cases of CNS MM that was diagnosed by cerebrospinal fluid cytology examination. Cerebrospinal fluid cytology examination can help to detect malignant cells and immu...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23600

    authors: Ren H,Zou Y,Zhao Y,Li J,Han X,He J,Guan H

    更新日期:2017-01-01 00:00:00

  • Are adjunctive markers useful in routine cervical cancer screening? Application of p16(INK4a) and HPV-PCR on ThinPrep samples with histological follow-up.

    abstract::The objectives of the study were to evaluate 1) the diagnostic sensitivity and specificity of p16(INK4a) as a marker for high-grade cervical lesions, 2) the results of a real-time polymerase chain reaction detecting high-risk human papillomavirus, and 3) the interobserver variability of the p16(INK4a) interpretation.A...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20822

    authors: Schledermann D,Andersen BT,Bisgaard K,Dohse M,Ejersbo D,Hoelund B,Horal P,Lindh M,Ryd W

    更新日期:2008-07-01 00:00:00

  • Cytological features of warthin-like papillary thyroid carcinoma: A case report with review of previous cytology cases.

    abstract::Warthin-like papillary thyroid carcinoma (WLPTC) is a rare morphological variant of papillary thyroid carcinoma which mimics various benign and malignant lesions on thyroid aspiration cytology. As correct cytological diagnosis is the cornerstone for appropriate patient management, awareness of the salient cytomorpholo...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.23739

    authors: Vallonthaiel AG,Agarwal S,Jain D,Yadav R,Damle NA

    更新日期:2017-09-01 00:00:00

  • Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): diagnosis with fine-needle aspiration in a case with nodal and nasal involvement.

    abstract::Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare entity characterized by the proliferation of cells belonging to the macrophage-histiocyte family, but whose exact origin is unknown. A case of SHML occurring in a 62-yr-old female is described in which the diagnosis is initially suggested by fine-needle...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840130413

    authors: Alvarez Alegret R,Martinez Tello A,Ramirez T,Gállego P,Martinez D,García Julían G

    更新日期:1995-11-01 00:00:00

  • Testicular cytology in azoospermia.

    abstract::Two hundred-seventy-five azoospermic males were subjected to fine-needle aspiration (FNA) cytologic study of testis with the aim of determining the cause of azoospermia; 534 aspirates from these patients were classified as follows: normal spermatogenesis (162), hypospermatogenesis (mild, moderate, or severe, 226), abs...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840090108

    authors: Verma AK,Basu D,Jayaram G

    更新日期:1993-01-01 00:00:00

  • Clinical performance of the aptima HPV assay in 4196 women with positive high-risk HPV and ASC-US cytology: A large women hospital experience.

    abstract:BACKGROUND:Despite Aptima assay as the latest US Food Drug Administration (FDA)-approved high-risk human papillomavirus (hrHPV) test has been implemented as an adjunct in cervical cancer screening for years, histological follow-up data remain limited with respect to its performance in women with ASC-US Pap tests and po...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24592

    authors: Wang T,Pradhan D,Zhang H,Matsko J,Zhao C

    更新日期:2021-01-01 00:00:00

  • Fine-needle aspiration cytology combined with flow cytometry immunophenotyping is a rapid and accurate approach for the evaluation of suspicious superficial lymphoid lesions.

    abstract::The authors report a prospective study on 88 samples of superficial lesions (lymph nodes, skin nodules, and breast tumors), performed by fine-needle aspiration cytology (FNAC) in 74 patients, allowing (i) morphologic analysis combined with immunophenotyping by flow cytometry (FCM) and (ii) a cytogenetic study in 33 ca...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20487

    authors: Mathiot C,Decaudin D,Klijanienko J,Couturier J,Salomon A,Dumont J,Vielh P

    更新日期:2006-07-01 00:00:00

  • Characteristic cytologic findings of epithelioid hemangioendothelioma: A case report and review of literature.

    abstract::Epithelioid hemangioendothelioma is a rare vascular neoplasm of low-grade malignancy. We observed a case of epithelioid hemangioendothelioma arising in a cervical lymph node. Fine needle aspiration cytology showed several characteristic findings of epithelioid hemangioendothelioma, that is, nuclear inclusion bodies, n...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21377

    authors: Kurisu Y,Tsuji M,Kuwabara H,Shibayama Y

    更新日期:2011-02-01 00:00:00

  • E-cadherin cell-adhesion molecule expression as a diagnostic adjunct in urothelial cytology.

    abstract::E-cadherin (E-CD) is a cell-adhesion molecule that has been associated with invasion and metastasis in a wide variety of human neoplasms. We have recently shown that, although decreased E-CD expression is associated with increased bladder-wall invasion and higher tumor grade of infiltrating transitional cell carcinoma...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0339(199605)14:4<310::AID-DC6>3

    authors: Ross JS,Cheung C,Sheehan C,del Rosario AD,Bui HX,Fisher HA

    更新日期:1996-06-01 00:00:00

  • Acquired myospherulosis secondary to gluteal augmentation on fine needle aspiration cytology: A diagnostic challenge.

    abstract::A 30-year-old female presented with a three-month history of a multilocular cystic lesion over the lumbosacral spine. Fine-needle aspiration biopsy (FNA) of the lesion was performed at an outside institution, and a cytologic diagnosis, suspicious for chordoma, was rendered. The patient presented for surgical consultat...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23871

    authors: Alperstein S,Dilcher T,Viswanathan K,Rao RA,Siddiqui MT,Giorgadze T

    更新日期:2018-05-01 00:00:00

  • A metastatic renal carcinoid tumor presenting as breast mass: a diagnostic dilemma.

    abstract::We present clinicopathological and cytological findings of a well-defined breast mass in a patient with history of primary renal carcinoid tumor. Fine-needle aspiration (FNA) cytology showed monotonous tumor cells with plasmacytoid appearance arranged singly and in small clusters. Occasional tumor cells were arranged ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20631

    authors: Hasteh F,Pu R,Michael CW

    更新日期:2007-05-01 00:00:00

  • Liquid fixation of endometrial brush cytology ensures a well-preserved, representative cell sample with frequent tissue correlation.

    abstract::Endometrium was obtained by brushing 656 hysterectomy specimens with a MedScand cytobrush (Hollywood, FL) in order to evaluate linking an easy-to-use liquid fixative with brush-sampling of the endometrium, and to determine the fixative's operating characteristics when applied to brush-sampling the endometrium. Liquid-...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0339(199605)14:4<367::AID-DC16>

    authors: Maksem JA,Knesel E

    更新日期:1996-06-01 00:00:00

  • Cytology of embryonal rhabdomyosarcoma: a cytologic, light microscopic, electron microscopic, and immunohistochemical study of seven cases.

    abstract::A correlated cytologic and histologic study of seven cases of embryonal rhabdomyosarcoma is presented. The diagnosis of rhabdomyosarcoma was established by light and electron microscopy and immunohistochemistry of the operative specimens. The cytologic appearance of the smears corresponded well with the histopathologi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840040405

    authors: Seidal T,Walaas L,Kindblom LG,Angervall L

    更新日期:1988-01-01 00:00:00

  • Intraoperative cytology of osseous lesions.

    abstract::Cytologic preparations were made from 53 biopsies of osseous and related lesions submitted for intraoperative diagnosis. Smears made by scraping the surface of the lesion and spreading the material obtained on a glass slide were most commonly used. These preparations were found to be valuable adjuncts to frozen sectio...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840020103

    authors: Wilkerson JA,Crowell WT

    更新日期:1986-01-01 00:00:00

  • Fine-needle aspiration of supraclavicular lymph nodes.

    abstract::Malignancies from many primary sites may metastasize to supraclavicular lymph nodes (SCLN). We reviewed 100 fine-needle aspirations (FNAs) of SCLNs. There were three major types of malignancy detected by this method: adenocarcinoma (n = 40), squamous cell carcinoma (n = 14), and other malignancies (n = 29). Adenocarci...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0339(199604)14:3<216::AID-DC4>3

    authors: Carson HJ,Candel AG,Gattuso P,Castelli MJ

    更新日期:1996-05-01 00:00:00

  • Primary pancreatic leiomyosarcoma with metastasis to the liver diagnosed by endoscopic ultrasound-guided fine needle aspiration and fine needle biopsy: A Case Report and Review of Literature.

    abstract::Primary pancreatic leiomyosarcomas are rare tumors of the pancreas that are usually diagnosed after resection or by biopsy. One case in the literature has utilized endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology. We report a second case of a primary pancreatic leiomyosarcoma that yielded diagnos...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.23540

    authors: Reyes MC,Huang X,Bain A,Ylagan L

    更新日期:2016-12-01 00:00:00

  • Fine-needle aspiration as the initial diagnostic modality in malignant lung disease.

    abstract::Cytologic detection of lung cancer is accepted, accurate, and time-honored. Typically, cytologic workup of a radiologic abnormality proceeds sequentially from sputum to bronchoalveolar cytology, and, if necessary, to fine-needle aspiration biopsy (FNA). Initial use of FNA in lung cancer diagnosis is controversial, but...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0339(199604)14:3<268::AID-DC14>

    authors: Blumenfeld W,Singer M,Glanz S,Hon M

    更新日期:1996-05-01 00:00:00

  • Primary B-cell lymphoma of the uterine cervix: Presentation in Pap-test slide and cervical biopsy.

    abstract::This case involved a 69-year-old female who presented with irritative urinary voiding. Imaging studies showed an 18-cm uterine mass centering on the cervix and extending into the bladder. The Pap test slide demonstrated necrotic background and degenerative changes in single and grouped atypical "small round blue cells...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23627

    authors: Yang G,Deisch J,Tavares M,Haixia Q,Cobb C,Raza AS

    更新日期:2017-03-01 00:00:00

  • Diagnostic impact of core-needle biopsy on fine-needle aspiration of non-Hodgkin lymphoma.

    abstract::We retrospectively reviewed 74 fine-needle aspiration (FNA) cases of presumptive non-Hodgkin lymphoma (NHL). All the cases had cytology and core-needle biopsy and 53 cases had concurrent flow cytometric analysis. FNA (cytology and flow cytometry) and core-needle biopsy were evaluated independently. FNA was diagnostic ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20082

    authors: Gong JZ,Snyder MJ,Lagoo AS,Vollmer RT,Dash RR,Madden JF,Buckley PJ,Jones CK

    更新日期:2004-07-01 00:00:00

  • Predictors of human papilloma virus in patients with keratinization.

    abstract::Given the prevalence of human papilloma virus (HPV) infection, an attempt was made to determine whether certain factors such as keratinization and/or squamous atypia are associated with its development. Review of our gynecologic cytology files from 1989 yielded 1,615 specimens showing parakeratosis and/or hyperkeratos...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840120107

    authors: Hudock J,Hanau CA,Hawthorne C,Jordan AG

    更新日期:1995-02-01 00:00:00

  • Concomitant neuroendocrine tumor and gastrointestinal stromal tumor in a duodenal fine needle aspiration: A cytologic clue for neurofibromatosis type 1.

    abstract::The identification of two cell populations displaying different cytologic characteristics in the same fine needle aspiration (FNA), one with an epithelioid appearance and the other spindle cell morphology, is an extremely rare phenomenon and potentially represents a source of diagnostic confusion. Depending on the lin...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24579

    authors: Tran TAN,Rosales A,Arnoletti JP,Ouyang J,Hasan MK

    更新日期:2021-02-01 00:00:00

  • Fine-needle aspiration cytology of breast: its impact on surgical practice with an emphasis on the diagnosis of breast abnormalities in young women.

    abstract::Fine-needle aspiration cytology (FNAC) of the breast is a minimally invasive yet maximally diagnostic method, often precluding the need of an open biopsy. In young women, in whom breast cancer is a rare disorder, it is also important that carcinoma is recognized without delay so that an appropriate plan of management ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.2840040306

    authors: Gupta RK,Naran S,Buchanan A,Fauck R,Simpson J

    更新日期:1988-01-01 00:00:00

  • Cytology of sclerosing epithelioid fibrosarcoma in pleural effusion.

    abstract::We report a case of sclerosing epithelioid fibrosarcoma focusing on its cytological features in pleural effusion. A 32-year-old man had noticed a tumor in his left buttock 5 years earlier but had not sought treatment because the tumor had been painless. He visited our hospital because the tumor had gradually increased...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21310

    authors: Tsuchido K,Yamada M,Satou T,Otsuki Y,Shimizu S,Kobayashi H

    更新日期:2010-10-01 00:00:00

  • Two AgNOR counts in fine-needle aspirates of lymphoproliferative disorders compared with acridine orange flow cytometry.

    abstract::Studies have shown that argyrophilic nucleolar organizer region-associated proteins (AgNORs) may correlate with DNA ploidy and/or proliferative activity in neoplastic and non-neoplastic conditions. However, studies have estimated only the mean AgNOR counts. Here we used two AgNOR counts, one of which may correlate wit...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840080208

    authors: Mourad WA,Katz RL,Sembera D,Atkinson EN,el-Naggar AK

    更新日期:1992-01-01 00:00:00

  • Diagnostic significance and possible pitfalls of nuclear grooves in extrathyroid cytology.

    abstract::The diagnostic significance of grooved nuclei in the cytology of extrathyroid lesions is not well-described in the literature. Isolated cases of metastatic adult granulosa cell tumor, reactive mesothelial hyperplasia, Langerhans' cell histiocytosis, recurrent renal cell carcinoma, and round cell liposarcoma were revie...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199701)16:1<57::aid-dc14>3

    authors: Ng WK,Collins RJ

    更新日期:1997-01-01 00:00:00

  • Malignant mixed tumor (carcinosarcoma) of parotid gland diagnosed by fine-needle aspiration biopsy.

    abstract::True malignant mixed tumor (carcinosarcoma) of salivary gland is a very rare neoplasm. Only one brief account of the Fine-Needle Aspiration Biopsy (FNAB) cytologic findings of this tumor was found in the literature. The authors report a case of malignant mixed tumor (chondrosarcoma and epidermoid carcinoma) arising fr...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840070419

    authors: Granger JK,Houn HY

    更新日期:1991-01-01 00:00:00

  • Pleomorphic adenoma with bizarre myoepithelial cells: A diagnostic challenge on cytologic smear.

    abstract::The diagnosis on fine needle aspiration of salivary gland tumors with a myoepithelial component is challenging because myoepithelial cells can have a wide cytomorphologic spectrum. The authors report a case of a pleomorphic adenoma of the parotid gland that expands the spectrum of appearances that myoepithelial cells ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24301

    authors: Taweevisit M,Thorner PS

    更新日期:2019-12-01 00:00:00

  • Follicular variant of papillary carcinoma: cytologic findings on FNAB samples-experience with 16 cases.

    abstract::Between January 1, 1992 and December 31, 1997, a cytopathological diagnosis of follicular variant of papillary thyroid carcinoma (FVPC) was made on a series of 16 out of 18 patients with palpable nodules who underwent fine-needle aspiration biopsy (FNAB) in our Department. The results of aspiration biopsy were followe...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2010

    authors: Fulciniti F,Benincasa G,Vetrani A,Palombini L

    更新日期:2001-08-01 00:00:00

  • Cervical tuberculosis detection in Papanicolaou-stained smear: case report with review of literature.

    abstract::Genital tract tuberculosis is usually secondary to an extragenital tubercular focus. Cervical tuberculosis, however, is rare accounting for up to 3% of all genital tract diseases. The diagnosis of tuberculosis is usually established on multiple cervical biopsies followed by bacteriological confirmation. There are only...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.21082

    authors: Gupta R,Dey P,Jain V,Gupta N

    更新日期:2009-08-01 00:00:00

  • Fine needle aspiration of secondary synovial sarcoma of the thyroid gland.

    abstract::Synovial sarcomas (SS) of the head and neck region are extremely rare and arise in only 5% of cases. We present a case of secondary SS of the thyroid originally diagnosed as medullary carcinoma on fine needle aspiration (FNA). A 41-year-old man presented with several weeks of dysphonia and a left thyroid mass. FNA of ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23327

    authors: Murro D,Slade JM,Syed S,Gattuso P

    更新日期:2015-11-01 00:00:00