Primary pancreatic leiomyosarcoma with metastasis to the liver diagnosed by endoscopic ultrasound-guided fine needle aspiration and fine needle biopsy: A Case Report and Review of Literature.

Abstract:

:Primary pancreatic leiomyosarcomas are rare tumors of the pancreas that are usually diagnosed after resection or by biopsy. One case in the literature has utilized endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology. We report a second case of a primary pancreatic leiomyosarcoma that yielded diagnostic material on EUS-FNA cytology. A 72-year-old female presented with 3-4 months of abdominal pain. A CT scan showed a large heterogeneous, lobulated pancreatic head and uncinate mass and multiple hypoattenuating liver lesions. An EUS-FNA was performed on one of the liver lesions with a 25-gauge needle, yielding an adequate sample with lesional cells. The initial read was a spindle cell neoplasm. A subsequent endoscopic ultrasound-guided fine needle biopsy with a 22-gauge needle was performed on the pancreatic head mass to rule out two primaries and to provide tissue for a mitotic index in the case of gastrointestinal tumor. Both the cell block of the EUS-FNA and the core biopsy were equally cellular and showed interlacing spindle cells that stained positive for SMA and negative for DOG-1, CD 117, and CD34. In addition, the core biopsy of the pancreas stained positive for Desmin. A diagnosis of a primary pancreatic leiomyosarcoma was made and the patient was started on systemic chemotherapy. Primary pancreatic leiomyosarcomas are rare pancreatic tumors that may yield diagnostic material by EUS-FNA with a 25-gauge needle. Diagn. Cytopathol. 2016;44:1070-1073. © 2016 Wiley Periodicals, Inc.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Reyes MC,Huang X,Bain A,Ylagan L

doi

10.1002/dc.23540

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

1070-1073

issue

12

eissn

8755-1039

issn

1097-0339

journal_volume

44

pub_type

杂志文章,评审
  • The importance of EZH2 and MOC-31 expression in the differential diagnosis of benign and malignant effusions.

    abstract:BACKGROUND:All malignant tumors may spread throughout the pleural, peritoneal, and pericardial cavities. The presence of tumor cells in serosal fluid is a poor prognostic indicator. It may be difficult to differentiate nuclear atypia of mesothelial cells due to injury of serosal surfaces from mesothelioma or malignant ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23653

    authors: Sadullahoglu C,Nart D,Veral A

    更新日期:2017-02-01 00:00:00

  • Familial mesothelioma in first degree relatives.

    abstract::Occupational asbestos exposure is believed to be the primary etiologic link to mesothelioma. However, in the evaluation of familial mesothelioma, it is important to consider the possibility of household exposure to asbestos. In this study, we report a family in which the father with prolonged occupational asbestos exp...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21859

    authors: Kalogeraki AM,Tamiolakis DJ,Lagoudaki ED,Papadakis MN,Papadakis GZ,Agelaki SI,Stathopoulos EN,Tzardi MN

    更新日期:2013-07-01 00:00:00

  • The use of gastric salvage cytology in the diagnosis of malignancy: a review of 731 cases.

    abstract::Over an 8-yr period at the Houston Veterans Hospital, 731 endoscopic gastric salvage cytologies were performed in 671 patients, with surgical biopsy also done in 660. Seventy-six patients subsequently had tissue biopsy-proven or resection-proven malignancies. Salvage cytology had a sensitivity of 91% and a specificity...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840060102

    authors: Green LK,Zachariah S,Graham DY

    更新日期:1990-01-01 00:00:00

  • An atypical morphologic presentation of Coccidioides spp. in fine-needle aspiration of lung.

    abstract::Infection due to Coccidioides spp., a dimorphic fungal pathogen, usually presents as a chronic pulmonary disease, occasionally with pulmonary nodules. On cytology, large spherules filled with endospores are typically seen. We report an unusual case of coccidioidomycosis in a 39-year-old female from an area nonendemic ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21613

    authors: Schuetz AN,Pisapia D,Yan J,Hoda RS

    更新日期:2012-02-01 00:00:00

  • Osteitis fibrosa cystica (brown tumor) of the spine with cord compression: report of a case with needle aspiration biopsy findings.

    abstract::A case of osteitis fibrosa cystica or brown tumor of bone in a patient presenting with acute spinal cord compression that was suggested initially by needle aspiration biopsy of the spine is described. Following the aspiration biopsy, excision of vertebral lesions, cord decompression, and spinal fusion were successfull...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840060512

    authors: Kashkari S,Kelly TR,Bethem D,Pepe RG

    更新日期:1990-01-01 00:00:00

  • Fine-needle aspiration cytology in azoospermic males.

    abstract::Bilateral testicular fine-needle aspiration cytology (FNAC) was performed in 100 males, including 10 controls with normal fertility and 90 infertile azoospermic males. The various seminiferous tubular cells were easily identified in smears. It was possible to give a cytological diagnosis in histologic terms by analysi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840070103

    authors: Rajwanshi A,Indudhara R,Goswami AK,Radhika S,Das A,Sharma SK,Vaidyanathan S,Datta BN

    更新日期:1991-01-01 00:00:00

  • Clear cell hepatocellular carcinoma diagnosed by bile duct brushing cytology.

    abstract::Clear cell hepatocellular carcinoma (CCHCC) is an uncommon morphologic variant of HCC and rarely invades into the main bile ducts. Here we describe a case of CCHCC that was diagnosed by bile duct brushing cytology. Liquid-based preparation of brushing specimen showed clusters of atypical epithelial cells with abundant...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23397

    authors: Fu LY,Mitchell KA,Cai G

    更新日期:2016-02-01 00:00:00

  • Two AgNOR counts in fine-needle aspirates of lymphoproliferative disorders compared with acridine orange flow cytometry.

    abstract::Studies have shown that argyrophilic nucleolar organizer region-associated proteins (AgNORs) may correlate with DNA ploidy and/or proliferative activity in neoplastic and non-neoplastic conditions. However, studies have estimated only the mean AgNOR counts. Here we used two AgNOR counts, one of which may correlate wit...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840080208

    authors: Mourad WA,Katz RL,Sembera D,Atkinson EN,el-Naggar AK

    更新日期:1992-01-01 00:00:00

  • Different expression about induced sputum cell sorting in the two main types of chronic obstructive pulmonary disease.

    abstract:BACKGROUND:The difference in expression of sputum cells types between the two main types of chronic obstructive pulmonary disease (COPD) is largely unknown. This study aims to investigate the difference and then wants to depend on sputum cells sorting to direct the treatment of COPD. METHODS:A total of 218 patients wi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23818

    authors: Song H,Yun C,Xu M,Sun D

    更新日期:2017-12-01 00:00:00

  • Logistic regression analysis of myxoid sarcomas: a cytologic study.

    abstract::The objective of this study was to identify key diagnostic cytologic criteria for the most common myxoid sarcomas studied by fine-needle aspiration cytology. We reviewed 27 myxoid malignant fibrous histiocytomas, 8 chordomas, 16 chondrosarcomas, and 12 myxoid liposarcomas in which both cytologic specimens and final hi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199811)19:5<355::aid-dc9>3

    authors: Layfield LJ,Liu K,Dodge RK

    更新日期:1998-11-01 00:00:00

  • Flow cytometric S-phase fraction as a complementary biological parameter for the cytological grading of non-Hodgkin's lymphoma.

    abstract::Fine-needle aspiration cytology (FNAC) is a technique that can overcome tissue-sampling disaggregation problems related to DNA flow cytometry analysis. The aim of this study, with long-term follow-up (median, 72 mo), was to investigate the prognostic value of DNA ploidy and S-phase fraction (SPF) in patients with non-...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.10298

    authors: Pinto AE,Cabeçadas J,Nóbrega SD,Mendonça E

    更新日期:2003-10-01 00:00:00

  • Fine-needle aspiration cytology of adrenal cryptococcosis: a case report.

    abstract::A case of adrenal cryptococcosis diagnosed by fine-needle aspiration biopsy cytology in a 58-yr-old man is presented. The organisms were easily seen with routine modified Wright stain (Diff-Quik) as variably sized yeasts, some with a brightly eosinophilic capsule. The diagnosis was confirmed with mucicarmine and silve...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840070123

    authors: Powers CN,Rupp GM,Maygarden SJ,Frable WJ

    更新日期:1991-01-01 00:00:00

  • A cancer of undetermined significance: Incidental thyroid carcinoma.

    abstract:INTRODUCTION:The incidence of thyroid cancer is increasing which can be attributed in part to improved ultrasonography (US) methods and increased detection of incidental thyroid carcinomas (ITC). We aimed to compare ITC with nonincidental thyroid carcinomas (NITC) in this study. METHODS:Retrospective analyses of 906 i...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24117

    authors: Evranos B,Polat SB,Cuhaci FN,Baser H,Topaloglu O,Kilicarslan A,Kilic M,Ersoy R,Cakir B

    更新日期:2019-05-01 00:00:00

  • Lymphomatous effusion of monomorphic epitheliotropic intestinal T-cell lymphoma is characterized by azurophilic granules and is a dismal sign: Report of two new cases with literature review.

    abstract::Lymphoma involving serous effusion is uncommon. The diagnosis of effusion lymphoma may be challenging, particularly when the lymphoid cells are small to medium-sized, which would be difficult for differentiating reactive effusions from low grade lymphomas. Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL)...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24690

    authors: Pan ST,Wang RC,Su YZ,Hsieh YC,Chuang SS

    更新日期:2021-01-02 00:00:00

  • Sensitivity of fine-needle aspiration for papillary carcinoma of the thyroid correlates with tumor size.

    abstract::Fine-needle aspiration (FNA) of the thyroid for papillary carcinomas is highly sensitive. We sought to determine if the sensitivity of FNA for papillary carcinoma is correlated with the size of the tumor. We reviewed the results of thyroid resections for the last 12 years and correlated the findings with clinical and ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21411

    authors: Renshaw AA

    更新日期:2011-07-01 00:00:00

  • Unusual presentation of disseminated histoplasmosis in an immunocompetent patient.

    abstract::Disseminated histoplasmosis (DH) is a systemic granulomatous disease caused by the fungus Histoplasma capsulatum. This disease occurs mainly in immunocompromised individuals with CD 4 counts less than 200 cell/µL and is rarely noted in immunocompetent person. In India, this disease has been reported from several parts...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23742

    authors: Kumari M,Udayakumar M,Kaushal M,Madaan GB

    更新日期:2017-09-01 00:00:00

  • Monophasic synovial sarcoma: a cytologic spectrum.

    abstract::Synovial sarcoma (SS) is a high-grade sarcoma that can be diagnosed in cytology with certainty only when it presents with a biphasic pattern. Monophasic SS (MSS), however, is a diagnostic consideration when a uniform spindle cell population is present. The purpose of this study was to evaluate a series of cytologic ca...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.10413

    authors: Ewing CA,Zakowski MF,Lin O

    更新日期:2004-01-01 00:00:00

  • Nodular fasciitis: spontaneous resolution following diagnosis by fine-needle aspiration.

    abstract::Nodular fasciitis can be histologically mistaken for a sarcoma. Typical cases are less than 5 cm and enlarge rapidly over days or weeks before diagnosis. The natural history of nodular fasciitis is unknown, since the diagnosis is usually based on excised lesions. Fine-needle aspiration of nodular fasciitis has been de...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840090316

    authors: Stanley MW,Skoog L,Tani EM,Horwitz CA

    更新日期:1993-01-01 00:00:00

  • Identification of intranuclear inclusions is useful for the cytological diagnosis of ovarian clear cell carcinoma.

    abstract:OBJECTIVE:The aim of this study was to clarify the diagnostic significance of the presence of intranuclear inclusions in clear cell carcinoma (CCC). MATERIALS AND METHODS:We analyzed 98 imprint specimens and 53 ascites specimens from 98 ovarian carcinoma cases [28 CCCs, 37 serous carcinomas (SCs), 22 endometrioid carc...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23322

    authors: Naka M,Ohishi Y,Kaku T,Watanabe S,Tamiya S,Ookubo F,Kato K,Oda Y,Sugishima S

    更新日期:2015-11-01 00:00:00

  • Rhabdoid meningioma: cytopathologic findings in cerebrospinal fluid.

    abstract::Rhabdoid meningioma is a recently described, rare, WHO Grade III intracranial tumor with an aggressive growth pattern and increased risk of recurrence. We describe the cytopathologic findings on cerebrospinal fluid of one such case in a 26-yr-old female who underwent resection of a left temporo-parietal mass. Cerebros...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.10374

    authors: Parwani AV,Mikolaenko I,Eberhart CG,Burger PC,Rosenthal DL,Ali SZ

    更新日期:2003-11-01 00:00:00

  • Diagnostic impact of core-needle biopsy on fine-needle aspiration of non-Hodgkin lymphoma.

    abstract::We retrospectively reviewed 74 fine-needle aspiration (FNA) cases of presumptive non-Hodgkin lymphoma (NHL). All the cases had cytology and core-needle biopsy and 53 cases had concurrent flow cytometric analysis. FNA (cytology and flow cytometry) and core-needle biopsy were evaluated independently. FNA was diagnostic ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20082

    authors: Gong JZ,Snyder MJ,Lagoo AS,Vollmer RT,Dash RR,Madden JF,Buckley PJ,Jones CK

    更新日期:2004-07-01 00:00:00

  • Leydig cell tumor of the testis: a cytohistological, immunohistochemical, and ultrastructural case study.

    abstract::We report a case of Leydig cell tumor of the testis in a young man, in whom preoperative diagnosis was achieved by fine-needle aspiration biopsy cytology. Cytology, histology, and ultrastructural examination showed diagnostic Reinke's crystals, both in nuclei and in cytoplasm. Immunohistochemistry displayed strong vim...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199703)16:3<262::aid-dc14>

    authors: Assi A,Sironi M,Bacchioni AM,Declich P,Cozzi L,Pasquinelli G

    更新日期:1997-03-01 00:00:00

  • Cytology-based gene mutation tests to predict response to anti-epidermal growth factor receptor therapy: a review.

    abstract::Recent therapeutic progresses in nonsmall cell lung cancer (NSCLC) and in colorectal cancer (CRC) are based on agents that specifically target the epidermal growth factor receptor (EGFR). To identify the patients most likely to benefit from such therapies, EGFR or KRAS gene mutation tests are mandatory, respectively, ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.21512

    authors: Malapelle U,Bellevicine C,Zeppa P,Palombini L,Troncone G

    更新日期:2011-09-01 00:00:00

  • Periosteal chondromyxoid fibroma: a case study using imprint cytology.

    abstract::Bone surface is an exceptional location for chondromyxoid fibroma. Only 14 cases of juxtacortical chondromyxoid fibroma have been reported to date and, to our knowledge, none of these cases are documented with imprint cytology. We report a case of periosteal chondromyxoid fibroma located in the distal tibial metaphysi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20357

    authors: Estrada-Villaseñor E,Cedillo ED,Martínez GR,Chávez RD

    更新日期:2005-12-01 00:00:00

  • Fine-needle aspiration cytodiagnosis of recurrent carcinoma of the breast in operative scars.

    abstract::Recurrence of carcinoma in scars following surgical treatment of breast carcinoma is a frequent problem. An early diagnosis of recurrent lesions is essential to enable timely management. In this study, the role of fine-needle aspiration cytology (FNAC) in the diagnosis of scar lesions was evaluated in 156 women seen o...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199701)16:1<14::aid-dc4>3.

    authors: Gupta RK

    更新日期:1997-01-01 00:00:00

  • Pleomorphic adenoma with predominant plasmocytoid myoepithelial cells: a diagnostic pitfall in aspiration cytology. Case report and review of the literature.

    abstract::Fine-needle aspiration (FNA) biopsy of the salivary gland is a sensitive and specific diagnostic tool. However, diagnostic problems are sometimes encountered in interpreting some cases, not only in differentiating benign from malignant cases but also in the specific classification of these neoplasms. We report a case ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.20954

    authors: Pusztaszeri M,Braunschweig R,Mihaescu A

    更新日期:2009-01-01 00:00:00

  • Role of fine-needle aspiration cytology and fluid cytology in extra-pulmonary tuberculosis.

    abstract::Extra-pulmonary tuberculosis is the presence of disease in an organ without obvious involvement of the lungs (World Health Organization, Tuberculosis Fact sheet, 2006). The present article focuses on the incidence of extra-pulmonary tuberculosis as an emerging and clinically significant disease to be reckoned with in ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.22827

    authors: Narayana Reddy RA,Narayana SM,Shariff S

    更新日期:2013-05-01 00:00:00

  • Cytopathological changes in human cervix and endometrium following prolonged retention of copper-bearing intrauterine contraceptive devices.

    abstract::Since 1971, cytological evaluation of cervical smears and endometrial aspirates was carried out in 604 women wearing CuT200 intrauterine contraceptive devices (IUDs) for periods ranging from 6 mo to 15 yr. No cases of cervical neoplasia or endometrial carcinoma were encountered, even after continuous use of the device...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840050302

    authors: Misra JS,Engineer AD,Tandon P

    更新日期:1989-01-01 00:00:00

  • Malignant effusions are sources of fibronectin and other promigratory and proinvasive components.

    abstract::Metastatic dissemination is the primary cause of death in ovarian cancer (OvCa) patients, and dissemination to pleural and peritoneal effusions is a common clinical event. Effusion samples were collected from 15 OvCa patients. Twenty-six samples were collected prospectively, two were archival, and eight were taken fro...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20279

    authors: Kohn EC,Travers LA,Kassis J,Broome U,Klominek J

    更新日期:2005-11-01 00:00:00

  • Polymicrobial lung infection in postrenal transplant recipient diagnosed by fine-needle aspiration cytology.

    abstract::Tuberculous and fungal infections are among the non-neoplastic lesions of the lung, in which fine-needle aspiration cytology (FNAC) has proven to be a useful technique in both immunocompromised and immunocompetent patients. The presence of polymicrobial infection in a renal transplant recipient is documented in the li...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21198

    authors: Duggal R,Rajwanshi A,Gupta N,Lal A,Singhal M

    更新日期:2010-04-01 00:00:00