Monophasic synovial sarcoma: a cytologic spectrum.

Abstract:

:Synovial sarcoma (SS) is a high-grade sarcoma that can be diagnosed in cytology with certainty only when it presents with a biphasic pattern. Monophasic SS (MSS), however, is a diagnostic consideration when a uniform spindle cell population is present. The purpose of this study was to evaluate a series of cytologic cases of MSS and its cytologic presentation. Twenty-one FNAs of histologically confirmed MSS were reviewed. Specimens consisted of tissue fragments and single cells containing scant granular cytoplasm, medium-sized nuclei, and coarse chromatin. A monotonous spindle pattern with comma-shaped nuclei was present in 5 cases. Sixteen cases contained oval and spindled nuclei. Eight of these specimens contained round nuclei, and 5 of these cases showed prominent nucleoli and cohesive clusters, reminiscent of biphasic SS. We conclude that a spectrum of cytologic findings can be seen in MSS, including a secondary population of cells with morphology usually typical of biphasic SS.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Ewing CA,Zakowski MF,Lin O

doi

10.1002/dc.10413

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

19-23

issue

1

eissn

8755-1039

issn

1097-0339

journal_volume

30

pub_type

杂志文章
  • Pleomorphic adenoma with bizarre myoepithelial cells: A diagnostic challenge on cytologic smear.

    abstract::The diagnosis on fine needle aspiration of salivary gland tumors with a myoepithelial component is challenging because myoepithelial cells can have a wide cytomorphologic spectrum. The authors report a case of a pleomorphic adenoma of the parotid gland that expands the spectrum of appearances that myoepithelial cells ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24301

    authors: Taweevisit M,Thorner PS

    更新日期:2019-12-01 00:00:00

  • Comparative cytologic findings of in situ and invasive adenocarcinoma of the uterine cervix.

    abstract::The cytologic findings in 13 cases of cervical adenocarcinoma in situ (mean age 33.9 yr) were compared with those in 9 cases of cervical invasive adenocarcinoma (mean age 45.7 yr). All diagnoses were confirmed by biopsy. The major differences found were that a necrotic background (66% invasive vs. 0% in situ) and macr...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840120206

    authors: Keyhani-Rofagha S,Brewer J,Prokorym P

    更新日期:1995-03-01 00:00:00

  • Breast care consultation center: role of the pathologist in a multidisciplinary center.

    abstract::The Breast Care Consultation Center (BCCC) is a multidisciplinary center providing, in a single setting, a complete outpatient facility for women who have been diagnosed with or suspected of having breast cancer. A team of specialists are available to provide comprehensive, diagnostic (radiologist, surgeon, and pathol...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199709)17:3<191::aid-dc4>3

    authors: Kanbour-Shakir A,Harris KM,Johnson RR,Kanbour AI

    更新日期:1997-09-01 00:00:00

  • Barr body in fine needle aspiration cytology of ovarian malignancies.

    abstract::The Barr body is the inactive X chromosome in a female somatic cell. It is readily identified as plano-convex structure of 2-3 micron in diameter on the periphery of the nuclear membrane. The aim of this study is to evaluate the significance of Barr body count in malignant ovarian tumors on fine needle aspiration cyto...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21688

    authors: Agrawal P,Dey P

    更新日期:2012-11-01 00:00:00

  • Cytopathologic characteristics of SMARCB1 (INI-1) deficient sinonasal carcinoma: A potential diagnostic pitfall.

    abstract::Tumors of the head and neck are extremely diverse and a subset are poorly differentiated and difficult to classify. Recently, a new entity has been described with rhabdoid and/or plasmacytoid cytologic features and a characteristic genetic signature-inactivation of the SMARCB1 (INI-1) tumor suppressor gene. To date, o...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23503

    authors: Allison DB,Bishop JA,Ali SZ

    更新日期:2016-08-01 00:00:00

  • Lipid-rich carcinoid tumor of the thymus gland: diagnosis by fine-needle aspiration biopsy.

    abstract::In this report we describe the cytologic features of an unusual thymic carcinoid tumor containing prominent cytoplasmic lipid vacuoles that was diagnosed by fine-needle aspiration biopsy. The tumor presented as a presternal subcutaneous mass in an 81-yr-old female, with a contiguous mediastinal mass on computed tomogr...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2020

    authors: Smith NL,Finley JL

    更新日期:2001-08-01 00:00:00

  • Papillary tissue fragments as a diagnostic pitfall in fine-needle aspirations of thyroid nodules.

    abstract::Fine-needle aspirates of three thyroid nodules displayed hypercellularity and papillary tissue fragments that suggested neoplasms. Neither microfollicles (either empty or with inspissated colloid) nor the characteristic nuclei of papillary carcinoma were evident. Surgical specimens contained adenomatoid nodules with f...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199705)16:5<454::aid-dc14>

    authors: Faser CR,Marley EF,Oertel YC

    更新日期:1997-05-01 00:00:00

  • A comparative study of 200 head and neck FNAs performed by a cytopathologist with versus without ultrasound guidance: evidence for improved diagnostic value with ultrasound guidance.

    abstract::Our previous study showed that the sensitivity of head and neck fine-needle aspiration (FNA) procedures was significantly better in the cytopathologist-performed group than in the noncytopathologist-performed group (96 versus 67%). Recently, cytopathologists have learned to use ultrasound machines to assist them in pe...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.21460

    authors: Wu M

    更新日期:2011-10-01 00:00:00

  • Retroperitoneal lymph node aspiration biopsy in staging of pelvic cancer: a cytological study of 228 consecutive cases.

    abstract::Knowledge of the status of the pelvic lymph nodes is important for accurate staging and adequate treatment of patients with genitourinary tract cancer (bladder and prostatic carcinoma, testicular tumors, and uterine carcinoma). A total of 228 consecutive patients underwent preoperative evaluation of the lymph node sta...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840030203

    authors: Cochand-Priollet B,Roger B,Boccon-Gibod I,Ferrand J,Faure B,Blery M

    更新日期:1987-06-01 00:00:00

  • Melanoma with cartilaginous differentiation: Diagnostic challenge on fine-needle aspiration with emphasis on differential diagnosis.

    abstract::Fine-needle aspiration (FNA) is a minimally invasive, fast, and accurate diagnostic method for the evaluation of patients with locally recurrent or distant metastases of malignant melanoma. In the vast majority of cases, the diagnosis is straightforward with the characteristic cytologic features well documented in the...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20952

    authors: Hanley KZ,Weiss SW,Logani S

    更新日期:2009-01-01 00:00:00

  • Dark and pale cerebriform nuclei in FNA smears of usual papillary thyroid carcinoma and its variants.

    abstract::The dark (hyperchromatic) cerebriform nucleus was recently described as a frequent finding in histopathology sections of papillary carcinoma of the thyroid. In the present study, we tried to determine the frequency of dark cerebriform nuclei in the fine-needle aspiration (FNA) smears of papillary thyroid carcinomas an...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20022

    authors: Mallik MK,Das DK,Mallik AA,Madda JP,Mirza K,Al-Bishi KK,George SS,Junaid TA

    更新日期:2004-03-01 00:00:00

  • Utility of CD138 (syndecan-1) in distinguishing carcinomas from mesotheliomas.

    abstract::CD138 (Syndecan-1) is a transmembrane heparan sulfate proteoglycan present on the surface of plasma cells and epithelial cells. CD138 is also expressed in some hematopoietic neoplasms and has recently been observed in carcinomas. We characterized CD138 expression in cell-block preparations of fluids/effusions, focusin...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20297

    authors: Saqi A,Yun SS,Yu GH,Alexis D,Taub RN,Powell CA,Borczuk AC

    更新日期:2005-08-01 00:00:00

  • Pancreatic lymphoma: A cytologic diagnosis challenge.

    abstract::Very rarely lymphoma primarily or secondarily involves the pancreas. Involvement of the pancreatic parenchyma with lymphoma clinically may mimic pancreatic ductal adenocarcinoma (PDA) and other mass-forming pancreatic lesions. Endoscopic ultrasound fine needle aspiration (EUS-FNA) is the first step in the diagnostic p...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24349

    authors: Savari O,Al-Duwal Z,Wang Z,Ganesan S,Danan-Rayes R,Ayub S

    更新日期:2020-04-01 00:00:00

  • Pseudoglandular schwannoma mimicking alveolar rhabdomyosarcoma: A diagnostic challenge on fine-needle cytology.

    abstract::Pseudoglandular schwannoma (PGS) is a rare morphological variant of benign schwannoma. PGS is quite distinct from the somewhat better characterized glandular schwannoma variant. PGS is characterized by the presence of gland-like structures lined with pseudocolumnar or cuboidal-like neoplastic Schwann cells lining vari...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24345

    authors: Yaprak Bayrak B,Vural Ç,Paksoy N

    更新日期:2020-03-01 00:00:00

  • Kba.62 and S100 protein expression in cytologic samples of metastatic malignant melanoma.

    abstract::The diagnosis of melanoma can be challenging, especially in metastatic lesions, due to the ability of melanoma cells to morphologically mimic carcinoma, sarcoma and even lymphoma cells. Moreover, melanomas can exhibit negative immunostaining for the melanoma markers HMB-45 and MART-1/Melan-A, often used in the diagnos...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.22948

    authors: Erdag G,Chowdhuri SR,Fetsch P,Erickson D,Hughes MS,Filie AC

    更新日期:2013-10-01 00:00:00

  • Cytomorphology of yolk sac tumor of the liver in fine-needle aspiration: a pediatric case.

    abstract::Yolk sac tumors (YST) in extragonadal locations are rare. Cytologic diagnosis of YST on fine-needle aspiration (FNA) smears may be a challenge to the cytopathologist. Further neo-adjuvant therapy may be based on cytologic diagnosis making accuracy important. We studied FNA material from a hepatic mass in a pediatric p...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20447

    authors: Gilbert KL,Bergman S,Dodd LG,Volmar KE,Creager AJ

    更新日期:2006-06-01 00:00:00

  • Fine-needle aspiration cytology of hepatic leiomyosarcoma.

    abstract::Hepatic leiomyosarcoma is a rare malignancy to involve the liver, occurring as a primary liver sarcoma in patients without an underlying medical disorder, as a metastatic malignancy, and with increasing incidence, as a primary tumor in AIDS patients. A series of hepatic leiomyosarcomas diagnosed by FNA biopsy, includi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840110403

    authors: Smith MB,Silverman JF,Raab SS,Towell BD,Geisinger KR

    更新日期:1994-12-01 00:00:00

  • The utility of ancillary studies in pediatric FNA cytology.

    abstract::We evaluated the diagnostic contribution of adjunct studies performed on aspirated material in the work-up of pediatric fine-needle aspiration (FNA) biopsies. Ancillary studies were performed on 54 of 136 (39.7%) pediatric FNA biopsies during a 5-year period. In 23 (16.9%) cases, immunocytochemical (ICC) studies, cons...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840080210

    authors: Gurley AM,Silverman JF,Lassaletta MM,Wiley JE,Holbrook CT,Joshi VV

    更新日期:1992-01-01 00:00:00

  • Are adjunctive markers useful in routine cervical cancer screening? Application of p16(INK4a) and HPV-PCR on ThinPrep samples with histological follow-up.

    abstract::The objectives of the study were to evaluate 1) the diagnostic sensitivity and specificity of p16(INK4a) as a marker for high-grade cervical lesions, 2) the results of a real-time polymerase chain reaction detecting high-risk human papillomavirus, and 3) the interobserver variability of the p16(INK4a) interpretation.A...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20822

    authors: Schledermann D,Andersen BT,Bisgaard K,Dohse M,Ejersbo D,Hoelund B,Horal P,Lindh M,Ryd W

    更新日期:2008-07-01 00:00:00

  • Cytomorphology of gastric and duodenal epithelium and reactivity to B72.3: a baseline for comparison to pancreatic lesions aspirated by EUS-FNAB.

    abstract::Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) has become a widely used method of pre-operatively evaluating pancreatic masses. This technique introduces gastrointestinal contamination into the specimen, which poses a diagnostic pitfall. The cytomorphologic features of these contaminants have no...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20343

    authors: Nagle JA,Wilbur DC,Pitman MB

    更新日期:2005-12-01 00:00:00

  • Fine-needle aspiration cytology in locally advanced breast adenocarcinoma: a case with complete response to preoperative chemotherapy in association with granulomatous inflammatory reaction.

    abstract::Preoperative chemotherapy for locally advanced breast carcinoma (stage IIIA,B) is increasingly utilized demonstrating a 70 to 95% objective response and 15 to 35% complete response. A 70-yr-old woman presented with a 9 cm left upper outer quadrant breast mass associated with overlying skin redness and a 2.5 cm left ax...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840100413

    authors: Costa MJ,Stewart G,Perez EA,Goodnight JE

    更新日期:1994-01-01 00:00:00

  • Fine needle aspiration of secondary synovial sarcoma of the thyroid gland.

    abstract::Synovial sarcomas (SS) of the head and neck region are extremely rare and arise in only 5% of cases. We present a case of secondary SS of the thyroid originally diagnosed as medullary carcinoma on fine needle aspiration (FNA). A 41-year-old man presented with several weeks of dysphonia and a left thyroid mass. FNA of ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23327

    authors: Murro D,Slade JM,Syed S,Gattuso P

    更新日期:2015-11-01 00:00:00

  • Parathyroid hormone assay in fine-needle aspirate is useful in differentiating inadvertently sampled parathyroid tissue from thyroid lesions.

    abstract::To assess the utility of chemical analysis for parathyroid hormone in the rinse (PTH-r) obtained via fine-needle aspiration (FNA) in the setting of inadvertently sampled parathyroid tissue or lesions (PTL) during "thyroid" or "neck" FNA, the authors review their experience at a large, tertiary care academic medical ce...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.20783

    authors: Owens CL,Rekhtman N,Sokoll L,Ali SZ

    更新日期:2008-04-01 00:00:00

  • Metastatic meningioma in fine-needle aspiration (FNA) of the lung: cytomorphologic finding.

    abstract::Pulmonary metastasis of intracranial meningioma is rare. We present the cytomorphologic features of such a tumor in a 71 yr-old woman who was found to have multiple lung nodules 13 years following the resection of an atypical intracranial meningioma. Cytomorphologic features were quite distinct and included hypercellu...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0339(199905)20:5<291::aid-dc8>3

    authors: Baisden BL,Hamper UM,Ali SZ

    更新日期:1999-05-01 00:00:00

  • Metastatic Signet-Ring Cell Carcinoma of the Bladder in Cerebrospinal Fluid.

    abstract::Primary bladder signet-ring cell carcinoma (SRCC) is extremely rare and associated with an aggressive course. To our knowledge, we describe the first metastatic bladder SRCC identified in cerebrospinal fluid (CSF). A 68-year-old male with 1 year history of primary bladder SRCC with spinal metastasis presented with mul...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23603

    authors: Lin DM,Park JW,Gattuso P

    更新日期:2017-01-01 00:00:00

  • Usefulness of imprint cytology of gonadoblastoma with dysgerminoma in a patient with Turner syndrome and a Y chromosome: A case report and literature review.

    abstract::Ovarian gonadoblastoma coexisting with a dysgerminoma is extremely rare in patients with Turner syndrome (TS) and a Y chromosome. The cytological findings, including imprint cytology, of these unusual ovarian tumors have rarely been reported. We report a rare patient with a gonadoblastoma with dysgerminoma, 3.0 × 2.0 ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.24282

    authors: Nagai T,Hasegawa K,Motegi E,Machida H,Sasaki H,Kato H,Kosaka N,Fukasawa I,Kuroda H

    更新日期:2019-11-01 00:00:00

  • Metastatic pheochromocytoma to the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration: A case report and review of literature.

    abstract::Pancreatic pheochromocytomas are rare and typically diagnosed by local resection. We present the first reported case of metastatic pheochromocytoma to the pancreas diagnosed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and cytology. A 67-year-old female presented with 2 to 3 months of abdominal pai...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审

    doi:10.1002/dc.24326

    authors: Yang SX,Dogra VS,Kothari TH,Reyes MCD

    更新日期:2020-03-01 00:00:00

  • Ubiquilin2 as a novel marker for detection of urothelial carcinoma cells in urine.

    abstract:BACKGROUND:Ubiquilin 2 (UBQLN2), an ubiquitin-related protein, is strongly expressed in urothelial carcinoma cells, in contrast to no or less expression in non-neoplastic cells; it protects cancer cells from reactive oxygen species (ROS)-induced cytotoxicity. In this study, we investigated whether UBQLN2 immunostaining...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.23332

    authors: Shimada K,Fujii T,Tatsumi Y,Anai S,Fujimoto K,Konishi N

    更新日期:2016-01-01 00:00:00

  • Functional parathyroid carcinoma. Cytology, histology, and ultrastructure of a case.

    abstract::A case of a functional parathyroid carcinoma that recurred 1 year after being resected is presented. The clinical and laboratory data and the histologic structure are presented with confirmatory electron microscopy. The preoperative aspiration biopsy showed findings suggestive of parathyroid carcinoma although simulta...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.2840010312

    authors: de la Garza S,Flores de la Garza E,Hernández Batres F

    更新日期:1985-07-01 00:00:00

  • Hyaluronic acid induced foreign body reaction mimicking neoplastic parotid cytology.

    abstract::Masses near the angle of the mandible containing extracellular matrix or mucin on cytology raise concern for various benign and malignant parotid gland neoplasms. Here a 76-year-old female with a history of cosmetic hyaluronic acid (HA) filler injections presented with a painless 6 mm left sided facial mass. Injection...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章

    doi:10.1002/dc.24202

    authors: Davis A,Basu D,Suyash M,Jalaly JB

    更新日期:2019-09-01 00:00:00