Abstract:
:We evaluated the diagnostic contribution of adjunct studies performed on aspirated material in the work-up of pediatric fine-needle aspiration (FNA) biopsies. Ancillary studies were performed on 54 of 136 (39.7%) pediatric FNA biopsies during a 5-year period. In 23 (16.9%) cases, immunocytochemical (ICC) studies, consisting of immunoperoxidase staining of direct smears and/or cell blocks or flow cytometric immunophenotyping, were performed. The studies were adequate in 14 cases (60.9%), suboptimal in five cases (21.7%), and inadequate in four cases (17.4%). Of the adequate and suboptimal cases, the ICC data helped to narrow the differential diagnosis or classify the disease process in eight cases (42.1%), confirmed cytologic impression in nine cases (47.4%), and gave contradictory results in two cases (10.5%). Adequate material for electron microscopy (EM) was obtained in 14/19 cases (73.7%). Ultrastructural studies were diagnostic, or helped classify the disease process in five cases (35.7%), confirmed the cytologic impression in four cases (28.6%), helped exclude diagnostic considerations in three cases (21.4%), and were judged to be non-contributory in two cases (14.3%). Cytogenetic studies revealed six of seven cases (all neoplasms) to have abnormal karyotypes. Special stains for organisms performed on smears from 25 cases including Ziehl-Neelsen, Gomori methenamine silver (GMS), Gram, and Warthin-Starry (WS) were negative except for 1/16 GMS and 4/9 Gram stains. In summary, we found that with appropriate case selection, ancillary studies performed on aspirated material can provide useful information in pediatric FNA cytology.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Gurley AM,Silverman JF,Lassaletta MM,Wiley JE,Holbrook CT,Joshi VVdoi
10.1002/dc.2840080210subject
Has Abstractpub_date
1992-01-01 00:00:00pages
137-46issue
2eissn
8755-1039issn
1097-0339journal_volume
8pub_type
杂志文章abstract::Sclerosing hemangioma of the lung is a rare benign neoplasm. The majority of the literature published on sclerosing hemangioma has focused on the histologic features, while only a few case reports have described the cytologic features. We report two additional cases of sclerosing hemangioma of the lung in which the cy...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21768
更新日期:2013-03-01 00:00:00
abstract::Primary lymphoma of the breast (PLB) is a rare disease, representing 0.04-0.5% of all malignant breast neoplasms. We present a patient with bilateral breast involvement by a high-grade diffuse large B-cell lymphoma, which was diagnosed initially by fine-needle aspiration cytology (FNAC). Mammography revealed a diffuse...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20184
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:1993-01-01 00:00:00
abstract::Although fine-needle aspiration (FNA) cytologic features of conventional papillary thyroid carcinoma (PTC) and some of its variants have been documented in the literature, PTC with an adenoid cystic pattern has not so far been described. A 35-year-old woman presented with solitary cold nodule in the right lobe of thyr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20063
更新日期:2004-06-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21429
更新日期:2011-09-01 00:00:00
abstract::Fifty-five cerebrospinal fluid (CSF) specimens from 42 patients with suspected meningeal tumor involvement were reviewed. Cytology in conjunction with immunocytochemistry identified 26 CSF specimens as malignant. There were fifteen cases of lymphoma, four cases of leukemia, two cases of carcinoma, and two cases of mel...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840120105
更新日期:1995-02-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840050212
更新日期:1989-01-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:2013-02-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23137
更新日期:2014-07-01 00:00:00
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21575
更新日期:2011-11-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840090316
更新日期:1993-01-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20497
更新日期:2006-10-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840090309
更新日期:1993-01-01 00:00:00
abstract::Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) has become a widely used method of pre-operatively evaluating pancreatic masses. This technique introduces gastrointestinal contamination into the specimen, which poses a diagnostic pitfall. The cytomorphologic features of these contaminants have no...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20343
更新日期:2005-12-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23133
更新日期:2015-02-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840020306
更新日期:1986-09-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21160
更新日期:2010-02-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20270
更新日期:2005-06-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:1999-08-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:2012-08-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(200004)22:4<218::aid-dc3>3
更新日期:2000-04-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840090611
更新日期:1993-12-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21078
更新日期:2009-10-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24662
更新日期:2020-11-16 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23380
更新日期:2015-12-01 00:00:00