Abstract:
:Ovarian gonadoblastoma coexisting with a dysgerminoma is extremely rare in patients with Turner syndrome (TS) and a Y chromosome. The cytological findings, including imprint cytology, of these unusual ovarian tumors have rarely been reported. We report a rare patient with a gonadoblastoma with dysgerminoma, 3.0 × 2.0 cm in size; she was a 19-year-old woman with TS and a Y chromosome. She underwent laparoscopic bilateral gonadectomy, and the tumor was classified as stage IA (pT1aNxM0) according to the International Federation of Gynecology and Obstetrics classification system. Intraoperative imprint cytology revealed two types of neoplastic cells: small tumor cells surrounding light green-stained or eosinophilic hyaline globules with marked calcification, suspicious for gonadoblastoma; and large, round, atypical cells with abundant cytoplasm, macronucleoli, and marked lymphocytic infiltration (two-cell pattern), suspicious for dysgerminoma. The cytology results in our patient may represent the second reported results of imprint cytology describing a gonadoblastoma with dysgerminoma. They are the first reported results in a patient with TS and a Y chromosome.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Nagai T,Hasegawa K,Motegi E,Machida H,Sasaki H,Kato H,Kosaka N,Fukasawa I,Kuroda Hdoi
10.1002/dc.24282subject
Has Abstractpub_date
2019-11-01 00:00:00pages
1203-1207issue
11eissn
8755-1039issn
1097-0339journal_volume
47pub_type
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更新日期:2016-10-01 00:00:00