Abstract:
:Polyomavirus BK (BKV) has ebeen identified as the main cause of polyomavirus-associated nephropathy, a major cause of renal allograft failure. Although BKV-associated nephropathy develops in only 2% to 5% of renal transplant recipients, its prognosis when present is very poor, with irreversible graft failure developing in 45% of affected patients. While the use of urine cytology for the detection of decoy cells has been in use for decades, other diagnostic modalities to detect BKV have emerged, including tissue biopsy, polymerase chain reaction, viral culture, and serology. Currently, there is no consensus regarding the laboratory technique best suited for clinical monitoring. This review article will discuss essential and clinical features of polyomavirus, followed by a discussion pertaining to the various diagnostic modalities that contribute to detecting polyomavirus-associated nephropathy.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Cimbaluk D,Pitelka L,Kluskens L,Gattuso Pdoi
10.1002/dc.21147subject
Has Abstractpub_date
2009-10-01 00:00:00pages
773-9issue
10eissn
8755-1039issn
1097-0339journal_volume
37pub_type
杂志文章,评审abstract::Ovarian tumors of sex-cord stromal derivation rarely exfoliate malignant cells in serous effusions. Adult granulosa cell tumor (AGCT) often presents as a stage I disease and association with ascites is about 10%. AGCT is rarely known to exfoliate tumor cells in the ascitic fluid. Exfoliation of malignant cells in the ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21675
更新日期:2012-10-01 00:00:00
abstract::The identification of two cell populations displaying different cytologic characteristics in the same fine needle aspiration (FNA), one with an epithelioid appearance and the other spindle cell morphology, is an extremely rare phenomenon and potentially represents a source of diagnostic confusion. Depending on the lin...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24579
更新日期:2021-02-01 00:00:00
abstract::Fine-needle aspiration (FNA) is a valuable technique to use in the evaluation of breast lesions; however, inadequate and discrepant diagnoses do occur. To identify the source and nature of inaccuracies related to the method we studied 39 cases in which FNA posed diagnostic problems. These problems could be attributed ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840070523
更新日期:1991-01-01 00:00:00
abstract::The dark (hyperchromatic) cerebriform nucleus was recently described as a frequent finding in histopathology sections of papillary carcinoma of the thyroid. In the present study, we tried to determine the frequency of dark cerebriform nuclei in the fine-needle aspiration (FNA) smears of papillary thyroid carcinomas an...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20022
更新日期:2004-03-01 00:00:00
abstract::Extramedullary multiple myeloma (EMM) involving the liver as a focal space-occupying lesion is very rare, especially in the patients with cirrhosis. Here, we report a case of EMM in the liver and periportal lymph node, diagnosed by endoscopic ultrasound guided-fine-needle aspiration (EUS-FNA). A 57-year-old male patie...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24416
更新日期:2020-07-01 00:00:00
abstract::Fine-needle aspiration biopsies from three patients with neuroblastoma were studied by light microscopy, and the morphologic findings were correlated with those from transmission and scanning electron microscopy. Light microscopic examination of the aspiration smears from all three cases revealed small and large round...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840040410
更新日期:1988-01-01 00:00:00
abstract::A silver staining technique was applied to 51 thyroid smears. The numbers of silver-stained nucleolar organizer regions (AgNORs) were counted, and the mean AgNOR and nuclear area per cell were determined with an image analyzer. The mean AgNOR count per cell was significantly higher in malignant than in benign lesions,...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0339(199603)14:2<140::AID-DC7>3
更新日期:1996-03-01 00:00:00
abstract::This study was designed to assess the utility of fine-needle aspiration cytology (FNAC) in the preoperative localization of parathyroid adenoma (PA). Fifty-seven samples from fifty-three cases of PA (four patients had bilateral disease) were obtained by ultrasound (US)-guided fine-needle aspiration. Parathyroid hormon...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21020
更新日期:2009-06-01 00:00:00
abstract::Non-Hodgkin lymphoma (NHL) is a heterogeneous group of lymphoid neoplasms and accurate subclassification is an essential prerequisite for proper management of patients. This study was aimed at evaluating the utility of nuclear morphometry and textural features on cytology smears to classify the cases of NHL on aspirat...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21154
更新日期:2010-02-01 00:00:00
abstract::We report a case of nodal nevus present in enlarged lymph nodes with changes of dermatopathic lymphadenopathy sampled by fine-needle aspiration (FNA) cytology prior to clinical evaluation of the patient. This lymph node pathology was established later by lymph node excisional biopsy, by which along with a skin biopsy ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20101
更新日期:2004-09-01 00:00:00
abstract::Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland neoplasm that is defined by ETV6-NTRK3 gene fusion. There have been few case reports on the cytopathologic features of MASC to date. We examined the clinicopathological and cytological features of seven cases of MASC defined by RT-PCR a...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23139
更新日期:2014-10-01 00:00:00
abstract::A series of 85 fine-needle aspiration (FNA) biopsies from orbital space occupying lesions of 82 patients are reviewed. A total of 32 benign lesions and 49 malignant lesions were conclusively diagnosed. In two cases the aspirates were insufficient for diagnosis. Of two cases, which were cytologically suspicious for lym...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20375
更新日期:2006-01-01 00:00:00
abstract::Anaplastic large cell lymphoma (ALCL), according to the new WHO classification, is a diagnosis limited to T/NK cell lymphomas. We present a case that demonstrates a new morphologic variant of ALCL with significant possible pitfalls for the cytopathologist. A fine-needle aspiration biopsy of a cervical lymph node showe...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10056
更新日期:2002-02-01 00:00:00
abstract::Very rarely lymphoma primarily or secondarily involves the pancreas. Involvement of the pancreatic parenchyma with lymphoma clinically may mimic pancreatic ductal adenocarcinoma (PDA) and other mass-forming pancreatic lesions. Endoscopic ultrasound fine needle aspiration (EUS-FNA) is the first step in the diagnostic p...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24349
更新日期:2020-04-01 00:00:00
abstract::Primary bladder signet-ring cell carcinoma (SRCC) is extremely rare and associated with an aggressive course. To our knowledge, we describe the first metastatic bladder SRCC identified in cerebrospinal fluid (CSF). A 68-year-old male with 1 year history of primary bladder SRCC with spinal metastasis presented with mul...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23603
更新日期:2017-01-01 00:00:00
abstract::Cysticercosis is caused by larval stage of Taenia solium called cysticercus cellulosae. Cysticercosis most commonly infects skeletal muscles, subcutaneous tissues, brain and ocular tissue. On extensive search of literature, only around 64 cases of lingual cysticercosis have been reported till date. We report a case of...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23828
更新日期:2018-03-01 00:00:00
abstract::Ovarian gonadoblastoma coexisting with a dysgerminoma is extremely rare in patients with Turner syndrome (TS) and a Y chromosome. The cytological findings, including imprint cytology, of these unusual ovarian tumors have rarely been reported. We report a rare patient with a gonadoblastoma with dysgerminoma, 3.0 × 2.0 ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.24282
更新日期:2019-11-01 00:00:00
abstract::Peculiar ring-like structures identified as Liesegang rings (LRs) were found in renal cyst fluid from three patients with benign renal cysts. They ranged in size from 5 to 820 mu. Most had a double-layer outer wall with equally spaced radial cross-striations and an amorphous central nidus. Special stains were performe...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840060310
更新日期:1990-01-01 00:00:00
abstract::We report the fine-needle aspiration cytology of a case of metastatic small cell osteosarcoma to the liver with rosette formation, originating from distal femur, in a 36-year-old female. The aspirate of the liver metastases revealed a relatively monomorphic population of mitotically active small blue round cells arran...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.22894
更新日期:2014-02-01 00:00:00
abstract::Sentinel lymph nodes (SLN) isolated in 40 patients of breast carcinoma (stage T(1)/T(2)) were evaluated intraoperatively by imprint cytology and frozen section. Rapid immunohistochemistry (IHC) was done in cases where both imprint smears and frozen sections were negative for any metastatic tumor deposits. The results ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21120
更新日期:2009-12-01 00:00:00
abstract::Herpes simplex is an uncommon cause of lower respiratory tract infection that requires prompt diagnosis and treatment to prevent late complications. We report two cases with simultaneous herpes simplex virus infection of the lower respiratory tract and lung carcinoma. Cytology of bronchial brushing and washing fluids ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20921
更新日期:2008-11-01 00:00:00
abstract::A correlated cytologic and histologic study of seven cases of embryonal rhabdomyosarcoma is presented. The diagnosis of rhabdomyosarcoma was established by light and electron microscopy and immunohistochemistry of the operative specimens. The cytologic appearance of the smears corresponded well with the histopathologi...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840040405
更新日期:1988-01-01 00:00:00
abstract::Lobular endocervical glandular hyperplasia (LEGH) is a cervical lesion with pyloric gland metaplasia. Minimal deviation adenocarcinoma (MDA) is an extremely well differentiated form of endocervical adenocarcinoma (AC). To date, it is difficult to differentiate LEGH from MDA because they share similar clinical, radiolo...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20859
更新日期:2008-08-01 00:00:00
abstract::Distinguishing metastatic carcinoma cells from reactive mesothelial cells in effusion samples is often challenging based on morphology alone. Metastatic carcinoma cells in fluid samples may mimic reactive mesothelial cells due to overlapping cytological features. We report a case of a pleural effusion in a 51-year-old...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.22915
更新日期:2014-03-01 00:00:00
abstract::The cytologic features of five cases of epithelial-myoepithelial carcinoma arising in major salivary glands (four parotid and one submandibular gland) are presented. All cases were initially diagnosed as low-grade malignancies. The smears were generally cellular, with no specific architectural pattern. Single cells an...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.10253
更新日期:2003-03-01 00:00:00
abstract::The study was carried out by the Human Reproduction Research Centre of the Indian Council of Medical Research at Lucknow and Kanpur, India as part of a multicenter study to ascertain the oncogenic potential of Norplant-I, a progestational contraceptive, by periodic cytological evaluation of cervical smears. In total, ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,多中心研究
doi:10.1002/dc.10326
更新日期:2003-09-01 00:00:00
abstract::Tenosynovial giant cell tumor (TSGCT) is a highly recurrent benign tumor of the extremities. Wide local excision is usually sufficient to achieve its recurrence-free outcome. However, that needs a confident pre-operative cytological diagnosis as TSGCT. Aspirates from this tumor express the characteristic polymorphic c...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23825
更新日期:2018-03-01 00:00:00
abstract::A case of florid microglandular hyperplasia of the uterine cervix that contained cells with severe atypia suggesting malignancy on a Papanicolaou smear is reviewed. Findings from 25 additional smears from patients with microglandular hyperplasia are reported. These sometimes contained glandular cells with varying degr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840070308
更新日期:1991-01-01 00:00:00
abstract::Psammoma body is a rare finding in a cervicovaginal smear and can be associated with either benign or malignant diseases. Here we report a case to illustrate the association of psammoma bodies with benign granulomatous reactions to a foreign material (aluminum silicate). ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199908)21:2<122::aid-dc8>3
更新日期:1999-08-01 00:00:00
abstract::Tuberculosis is one of the oldest diseases known to affect humans and is caused by Mycobacterium tuberculosis. Lymph nodes are the most common site of extrapulmonary involvement. Tuberculous lymphadenitis can be presumptively diagnosed morphologically on fine-needle aspiration biopsy of lymph nodes. Additional tests l...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21860
更新日期:2013-04-01 00:00:00