Abstract:
:This study was designed to assess the utility of fine-needle aspiration cytology (FNAC) in the preoperative localization of parathyroid adenoma (PA). Fifty-seven samples from fifty-three cases of PA (four patients had bilateral disease) were obtained by ultrasound (US)-guided fine-needle aspiration. Parathyroid hormone (PTH) estimation was performed on the supernatant of the aspirated fluid on all cases. Subsequently, all of them underwent cytologic evaluation. The cytology slides were evaluated using the following criteria: Cellularity, architectural patterns, bare nuclei in the background, nuclear morphology, and background features (colloid-like material or macrophages). Parathyroid cells were seen in 23 samples (40.4%). The cellularity of the smears was insufficient for interpretation in 16 samples (28.1%); and thyroid follicles and colloid were seen in 18 samples (31.5%). Majority of the samples with parathyroid cells showed moderate cellularity with monomorphous round to slightly oval cells predominantly arranged in loose two-dimensional clusters with occasional papillary fragments. Majority of them exhibited a stippled nuclear chromatin. No significant pleomorphism, mitotic activity, or prominent nucleoli were observed. Most samples showed bare nuclei in the background. In conclusion, US-guided FNAC has its limitations because of low sensitivity in primary localization of the parathyroid adenoma in cases of primary hyperparathyroidism and is not a useful mode of investigation in cases of PA.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Agarwal AM,Bentz JS,Hungerford R,Abraham Ddoi
10.1002/dc.21020subject
Has Abstractpub_date
2009-06-01 00:00:00pages
407-10issue
6eissn
8755-1039issn
1097-0339journal_volume
37pub_type
杂志文章abstract::The objective of this study was to evaluate the cytologic spectrum of small cell lesions of liver as diagnosed by fine-needle aspiration (FNA). Of 304 FNAs of liver that were performed in our institution between 1990 and 1994, 29 were classified as small-cell lesions. The final diagnoses were as follows: small-cell un...
journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
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abstract::Ameloblastic fibroma of the jaw is a rare, benign mixed odontogenic tumor, having little tendency for local invasion and a low recurrence rate. Cytologic distinction from ameloblastoma, ameloblastic fibrosarcoma, and intraosseous adenoid cystic carcinoma is necessary, in view of the different biologic behavior. A pain...
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21104
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journal_title:Diagnostic cytopathology
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
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更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2001-02-01 00:00:00
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pub_type: 杂志文章
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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更新日期:1998-10-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20841
更新日期:2008-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2009-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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journal_title:Diagnostic cytopathology
pub_type: 杂志文章
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journal_title:Diagnostic cytopathology
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更新日期:2017-03-01 00:00:00
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journal_title:Diagnostic cytopathology
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更新日期:2020-12-01 00:00:00
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更新日期:1997-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2008-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-07-01 00:00:00