Abstract:
:Fine-needle aspiration cytology, immunocytochemistry, and electron microscopic findings are described in a case of glycogen-rich clear cell carcinoma of the breast. The aspirate contained many small and large papillary cell groups and numerous single tall columnar cells with apical cytoplasmic projections and mild to moderate degree of nuclear pleomorphism. Cytochemical localisation of glycogen and immunostaining on air-dried smears with CEA and actin monoclonal antibodies permitted the correct identification and differential diagnosis of the tumor. Electron microscopic examination of the resected specimen confirmed the diagnosis of glycogen-rich clear cell carcinoma. The differential diagnosis and potential diagnostic pitfalls are discussed, and recommendation are offered to prevent misdiagnosis.
journal_name
Diagn Cytopatholjournal_title
Diagnostic cytopathologyauthors
Alexiev BAdoi
10.1002/dc.2840120115subject
Has Abstractpub_date
1995-02-01 00:00:00pages
62-6issue
1eissn
8755-1039issn
1097-0339journal_volume
12pub_type
杂志文章abstract::Knowledge of the status of the pelvic lymph nodes is important for accurate staging and adequate treatment of patients with genitourinary tract cancer (bladder and prostatic carcinoma, testicular tumors, and uterine carcinoma). A total of 228 consecutive patients underwent preoperative evaluation of the lymph node sta...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840030203
更新日期:1987-06-01 00:00:00
abstract::Nodular fasciitis can be histologically mistaken for a sarcoma. Typical cases are less than 5 cm and enlarge rapidly over days or weeks before diagnosis. The natural history of nodular fasciitis is unknown, since the diagnosis is usually based on excised lesions. Fine-needle aspiration of nodular fasciitis has been de...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840090316
更新日期:1993-01-01 00:00:00
abstract::Vaginal reconstruction has become an established method to restore sexual function in women who have undergone ultraradical surgery and/or irradiation for the treatment of gynecologic malignancies. Cytologic evaluation of the neovagina serves a major role in the detection of recurrent disease. The purpose of this retr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840130106
更新日期:1995-07-01 00:00:00
abstract::Clear cell hepatocellular carcinoma (CCHCC) is an uncommon morphologic variant of HCC and rarely invades into the main bile ducts. Here we describe a case of CCHCC that was diagnosed by bile duct brushing cytology. Liquid-based preparation of brushing specimen showed clusters of atypical epithelial cells with abundant...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23397
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Fine-needle aspiration (FNA) is commonly used to investigate lymphadenopathy of suspected metastatic origin. While diagnostic accuracy of FNA for lymph node disease is well described, the relationship between node size, percent tumor replacement, and size of metastatic deposit with diagnostic accuracy is les...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24617
更新日期:2021-02-01 00:00:00
abstract::A case of osteitis fibrosa cystica or brown tumor of bone in a patient presenting with acute spinal cord compression that was suggested initially by needle aspiration biopsy of the spine is described. Following the aspiration biopsy, excision of vertebral lesions, cord decompression, and spinal fusion were successfull...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840060512
更新日期:1990-01-01 00:00:00
abstract::Nephroblastoma (Wilms' tumor) is the most common childhood renal tumor and usually presents with a histology and cytology consisting of blastemal, epithelial, and stromal cells. Effusions are not uncommon and may suggest an unfavorable prognosis when containing anaplastic tumor cells. In the present case, we report th...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20535
更新日期:2006-09-01 00:00:00
abstract::Mycobacterial infection, tuberculosis (TB) in particular, remains one of the world's deadliest communicable diseases in adults and particularly in children, in low and middle income countries. The combination of human immunodeficiency virus (HIV) and TB is often lethal with TB accounting for 25% of deaths in the HIV p...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23410
更新日期:2016-03-01 00:00:00
abstract::Myeloproliferative disease may be associated with extramedullary hematopoiesis (EH). Clinically, however, the differential diagnosis of solid masses in these patients includes not only EH but also inflammatory lesions and malignant neoplasms, including granulocytic sarcoma. We report the fine-needle aspiration (FNA) c...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840090510
更新日期:1993-10-01 00:00:00
abstract::Pancreatic adenocarcinoma is a genetic disease showing somatic mutations of multiple genes, including SMAD4. SMAD4 is a tumor suppressor gene that is inactivated in a sub-set of pancreatic adenocarcinoma, either by the intragenic mutation of one allele in combination with the loss of the other allele or by homozygous ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20715
更新日期:2007-10-01 00:00:00
abstract::The aim of this study were (1) To correlate koilocytosis with high risk HPV(HrHPV) DNA in urinary bladder carcinoma and (2) To compare detection of koilocytosis on tissue sections and urine cytology. Biopsy and cytologic specimens from 33 patients of urinary bladder carcinoma were analyzed. HPV DNA was detected by PCR...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.20978
更新日期:2009-03-01 00:00:00
abstract::A case of nodular lesion of the breast in a 37 year old female caused by filariasis is described. The case is instructive since the diagnosis was made by fine-needle aspiration cytology. ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840080419
更新日期:1992-01-01 00:00:00
abstract::Four cases of renal angiomyolipoma (AML) diagnosed by fine-needle aspiration biopsy (FNAB) are reported. One case was associated with the clinical complex of tuberous sclerosis. The tumors were solitary in two cases and multiple and bilateral in the fourth. The cytologic features of the four cases were similar to thos...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840100110
更新日期:1994-01-01 00:00:00
abstract::Our previous study showed that the sensitivity of head and neck fine-needle aspiration (FNA) procedures was significantly better in the cytopathologist-performed group than in the noncytopathologist-performed group (96 versus 67%). Recently, cytopathologists have learned to use ultrasound machines to assist them in pe...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.21460
更新日期:2011-10-01 00:00:00
abstract::Ciliated muconodular papillary tumors (CMPTs) of the lung are rare, likely benign neoplastic lesions. Here we describe a case of a CMPT, focusing on its cytologic features, which to our knowledge have not been reported previously. Owing to dull back pain, a 69-year-old male non-smoker underwent CT, which revealed a 1....
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24169
更新日期:2019-07-01 00:00:00
abstract::Chondroid syringoma (CS) is a rare benign adnexal tumor of the skin with a resemblance to pleomorphic adenoma of salivary gland, most commonly involving the head and neck region. In the present literature, reports of the cytologic appearance of CS are scarce as it is rarely encountered by fine needle aspiration (FNA)....
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23424
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:This study aims to assess in our institutional experience the accuracy of fine needle aspiration cytology (FNAC) in the diagnosis of salivary gland masses (SGM) according to the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) and to an in-house system. METHODS:The study included 189 FNACs c...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24682
更新日期:2020-12-21 00:00:00
abstract::Calcinosis cutis is an uncommon condition, and calcific deposits in patients with end-stage renal disease are now somewhat rare, due to improvement in management. Since calcific deposits may clinically resemble a tumor, it is feasible to investigate them by fine-needle aspiration cytology (FNAC). A 52-yr-old male with...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199812)19:6<465::aid-dc13>
更新日期:1998-12-01 00:00:00
abstract::Primary hydatid disease of the skeletal muscle without systemic involvement is rare. The purpose of this report is to document the novel clinical presentation and the interesting facets of fine-needle aspiration in a case of hydatid disease. It was a case of primary hydatid cyst of the left supraspinatus muscle in an ...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.22925
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Since its inception in 1995, the Ultrafast Papanicoloau (UFPAP) cytological stain has undergone a number of modifications to suit the local availability of reagents and cost in different set ups. However, the reported results have been uniformly encouraging. We designed a study to investigate the inter-obser...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23897
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The noninvasive encapsulated follicular variant of papillary carcinoma (nEFVPTC) has recently been reclassified to "noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)," removing this entity from the malignant category. This re-categorization has had major implications for cl...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23863
更新日期:2018-02-01 00:00:00
abstract::We report a rare case of extranodal NK/T-cell lymphoma, nasal type of the uterine cervix that showed cytologic features mimicking cervical cancer. A 65-year-old woman presented with vaginal bleeding. Gynecological examination revealed a bulky tumor of the cervix. A conventional Papanicolaou-stained cervical smear show...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.23439
更新日期:2016-05-01 00:00:00
abstract::We describe the cytomorphology of seven cases of metaplastic carcinoma of the breast studied by fine-needle aspiration cytology and by histology. All seven cases contained foci of ductual adenocarcinoma. This finding was combined with heterologous mesenchymal elements in four cases, a spindle-cell pattern of growth in...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840050106
更新日期:1989-01-01 00:00:00
abstract::Human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is a unique form of carcinoma that largely arises from the tonsillar tissue in the oropharynx. These tumors often present with cervical lymphadenopathy resulting in a fine needle aspiration (FNA) biopsy. Use of the cytology specimen to de...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章,评审
doi:10.1002/dc.23668
更新日期:2017-03-01 00:00:00
abstract::The standard screening test for detecting cervical lesions and cancers is a Papanicolaou (Pap) smear. While squamous cell abnormalities remain the most common positive Pap test result, cytologic findings of glandular cell abnormalities have become more frequent in recent decades. The 2014 Bethesda System for reporting...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.24421
更新日期:2020-09-01 00:00:00
abstract::Cytological and histological findings of a rare case of a malignant phyllodes tumor (with liposarcomatous components) of the breast are presented. The atypia of the stromal cells and naked nuclei in a lesion considered benign clinically and on imaging alerted us to the possibility of a phyllodes tumor, despite the low...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(200006)22:6<364::aid-dc7>3
更新日期:2000-06-01 00:00:00
abstract::p53 and proliferating cell nuclear antigen (PCNA) status was determined in fine-needle aspirates (FNAs) and methacarn-fixed paraffin-embedded tissue sections of six fibroadenomas and 50 primary breast carcinomas using supersensitive monoclonal antibodies and the biotin-streptavidin-amplified method. Nuclear accumulati...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0339(199611)15:4<277::AID-DC5>3
更新日期:1996-11-01 00:00:00
abstract::Adenomyoepithelioma is an uncommon tumor of the breast which clinically presents as a discrete nodule and histologically is composed of lumenal spaces lined by a mixture of epithelial and myoepithelial cells. It has a spectrum of histologic appearances which are gradually gaining wider recognition. There are, however,...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840120311
更新日期:1995-05-01 00:00:00
abstract::Most granulomas of the prostate are nonspecific; infectious, post-operative, and allergic lesions are much less common. Fine-needle aspiration findings in the typical case are distinctive and easily recognized. Several series have been reported, but few have included histologic follow-up. We describe three cases of gr...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/dc.2840070513
更新日期:1991-01-01 00:00:00
abstract::We report a case of Leydig cell tumor of the testis in a young man, in whom preoperative diagnosis was achieved by fine-needle aspiration biopsy cytology. Cytology, histology, and ultrastructural examination showed diagnostic Reinke's crystals, both in nuclei and in cytoplasm. Immunohistochemistry displayed strong vim...
journal_title:Diagnostic cytopathology
pub_type: 杂志文章
doi:10.1002/(sici)1097-0339(199703)16:3<262::aid-dc14>
更新日期:1997-03-01 00:00:00