[Definition and control of the processes involved in the quality management].

abstract：:The analysis of longitudinal series of tumour markers during chemotherapy in patients with germ cells tumors is not easy. The purpose of this work is to present various characteristic profiles of the evolution of serum human chorionic gonadotropin during chemotherapy and review the modalities of the dynamic interpreta...

journal_title：Annales de biologie clinique

authors： Riedinger JM,Eche N,Fargeot P

更新日期：2008-09-01 00:00:00

abstract：:We resume here the guidelines about sample processing and transport for laboratory tests. All the steps of the pre-examination phase process, downstream to the recording of the requests, are described in this document. The purpose is to assure a secure and optimal sample management. The traceability of all the steps o...

journal_title：Annales de biologie clinique

authors： Annette-Reisch M,Soubiran P,Szymanowicz A,membres du sous-groupe 1 pré-analytique.

更新日期：2010-12-01 00:00:00

abstract：:Monoclonal antibodies have been raised against porcine LH receptor and allowed to clone the corresponding messenger RNA from testicular cells. Cross hybridisation with the LH receptor clone allowed to isolate a clone corresponding to the human TSH receptor from thyroids. The structure of both receptors have been deter...

journal_title：Annales de biologie clinique

authors： Misrahi M,Loosfelt H,Atger M,Vu Hai MT,Gross B,Meduri G,Jolivet A,Milgrom E

更新日期：1992-01-01 00:00:00

abstract：:Nowadays, physiological amino acids profiling is based primarily on ion exchange chromatography (IEC) coupled to a post-column derivatization with ninhydrin and UV detection at two wavelengths. Unfortunately, this technique suffers various drawbacks such as long analysis time, high sample volume and specific costs rel...

journal_title：Annales de biologie clinique

authors： Boemer F,Schoos R,Deberg M

更新日期：2015-07-01 00:00:00

abstract：:The relations between chromosomal diseases and mental retardation can be envisaged in three different ways: 1) Pharmacological approach shows a peculiar sensitivity of the cholinergic system in trisomic 21 children. A trouble in the manufacture of cholinergic mediator is plausible. 2) General biochemistry shows a slig...

journal_title：Annales de biologie clinique

authors： Lejeune J

更新日期：1978-01-01 00:00:00

abstract：:Acquired recurrent cytogenetic abnormalities are frequent in chronic lymphocytic leukaemia (CLL). They can be associated with good or poor prognostic factors, and also with gene mutations. Chromosomal abnormalities could be clonal or sub-clonal. Assessing the TP53 status (deletion/mutation) is currently mandatory befo...

journal_title：Annales de biologie clinique

authors： Nguyen-Khac F,Borie C,Callet-Bauchu E,Eclache V,Struski S

更新日期：2016-10-01 00:00:00

abstract：:The recent development of specific and sensitive biochemical markers reflecting the overall rate of bone formation and bone resorption, has markedly improved the non invasive assessment of bone turnover in various metabolic bone diseases, especially for osteoporosis. The immunoassay of human osteocalcin recognizing th...

journal_title：Annales de biologie clinique

authors： Garnero P,Delmas PD

更新日期：1999-03-01 00:00:00

abstract：:Premature rupture of the membranes (PROM) is a frequent event affecting 3% of pregnancies. PROM causes 30% of premature deliveries and 20% of perinatal mortality. The diagnosis relies mainly on the clinical visualization of the amniotic fluid flow in the vagina. If not, clinicians can use bedside tests detecting eithe...

journal_title：Annales de biologie clinique

authors： Julien M,N'guema L,Bouzerara A,Toro B,Lecarpentier E,Guibourdenche J

更新日期：2018-06-01 00:00:00

abstract：:Peripheral gangrene with disseminated intravascular coagulation (DIC) during severe Plasmodium falciparum malaria has already been described but is unfrequent. We report here the case of a 62-year-old man admitted in the intensive care unit of our hospital for severe Plasmodium falciparum malaria with disseminated int...

journal_title：Annales de biologie clinique

authors： Tessier-Marteau A,Cruguel Sl,Grand F,Asfar P,Zandecki M,Macchi L

更新日期：2009-09-01 00:00:00

abstract：:Micro- and nanospheres are tightly associated with the development of flow cytometry. They are indispensable tools to optimize diffraction and fluorescence signals as well as for fluorescence calibration and cellular purification (magnetic micro- and nanospheres). They are also usefull to evaluate phagocytosis and to ...

journal_title：Annales de biologie clinique

authors： Lizard G,Monier S,Prunet C,Duvillard L,Gambert P

更新日期：2004-01-01 00:00:00

abstract：:It is often reminded that if the ionized calcium is not measured, the interpretation of total calcemia should consider serum albumin. Two formulas are usually employed: ["Corrected" Ca (mmol/L) = Ca measured (mmol/L) + 0.020 or 0.025 (40 - albumin (g/L))]. This adjustment formula arises from works of Payne published i...

journal_title：Annales de biologie clinique

authors： Parent X,Spielmann C,Hanser AM

更新日期：2009-07-01 00:00:00

abstract：:Elderly patients are at high risk of over-anticoagulation and of haemorrhagic risk when on warfarin, especially during treatment induction. In Charles Foix Hospital, a 800-bed geriatric hospital, we specifically developed for in-patients older than 70 years (target INR 2.5) a simple low-dose warfarin induction regimen...

journal_title：Annales de biologie clinique

authors： Siguret V,N'Guyen A,Harboun M,Chevallier A,Pautas E,Gouin-Thibault I,Berigaud S

更新日期：2006-05-01 00:00:00

abstract：:Twenty-two amino acids are measured in cerebrospinal fluid of fourty patients with senile dementia of the Alzheimer type (SDAT) and of ten age matched healthy control subjects. There is no significant difference between these two groups. ...

journal_title：Annales de biologie clinique

authors： Gelot MA,Jeandel C,Belleville F,Nabet P,Penin F,Cuny G

更新日期：1990-01-01 00:00:00

abstract：:The aim of the present work was to assess the genetic and antigenic variability in the VP1 region of type 3 echviruses (E-3), an enterovirus serotype associated to meningitis, neuro-muscular diseases and type 1 diabetes in human. Forty-six VP1 sequences of E-3, among which 9 were isolated in tunisian infants, were inc...

journal_title：Annales de biologie clinique

authors： Farès W,Rezig D,Yahia AB,Touzi H,Meddeb Z,Triki H

更新日期：2012-03-01 00:00:00

abstract：:Guanidinoacetate (GAA) and creatine (Cr) are creatine deficiency syndromes (CDS) biochemical markers. We describe a liquid chromatography - tandem mass spectrometry method (LC/MSMS) performing simultaneous analysis of GAA, Cr and creatinine (Crn). Study of Cr uptake by fibroblasts for Cr transporter defect diagnosis i...

journal_title：Annales de biologie clinique

authors： Van Noolen L,Monneret D,Ducros V,Corne C,Lunardi J,Faure P

更新日期：2013-07-01 00:00:00

abstract：:The search for sperm is part of the examinations wich may be prescribed, following a request of jucicial services, in case of a suspicion of sexual assault. This article applies to detail how the different phases, pre-analytical, analytical and post-analytical, must be absolutely adhered to so that the biologist, expe...

journal_title：Annales de biologie clinique

authors： Laudat A,Lecourbe K

更新日期：2008-09-01 00:00:00

abstract：:Monoclonal antibodies are being used as drugs in the diagnosis, prevention, and treatment of human diseases. The discipline of antibody engineering has evolved with modern cellular and molecular biology methods to meet the challenge of producing human monoclonal antibodies for in vivo biotherapy. In this overview, app...

journal_title：Annales de biologie clinique

authors： Hamilton RG

更新日期：1989-01-01 00:00:00

abstract：:ATB 32 GN was tested with 279 gram negative non fastidious rods = 188 Enterobacteriaceae and 91 non-enterobacteriaceae. This micro-method included 32 carbon substrate's assimilation tests, read and interpreted automatically after incubation for one or two days at 30 degrees C. 93.5 p. cent of all bacteria are correctl...

journal_title：Annales de biologie clinique

authors： Croize J,Rouhan D,Le Noc P

更新日期：1987-01-01 00:00:00

abstract：:Albumin is the major circulating protein. It plays a fundamental role maintaining intra-vascular oncotic pressure and carrying many endogenous and exogenous substances. Variations of plasma albumin levels can be physiologic or pathologic and both qualitative and quantitative (more frequent) disorders are regrouped und...

journal_title：Annales de biologie clinique

authors： Bach-Ngohou K,Schmitt S,Le Carrer D,Masson D,Denis M

更新日期：2005-03-01 00:00:00

abstract：:Urinary ammonium excretion is the best parameter to quantify net acid excretion by the kidney. As measurement of ammonium excretion is not routinely available, clinicians use formulas to estimate NH(4)+ excretion. However, the measurement of urinary NH(4)+ concentration can be performed by an automatically method, whi...

journal_title：Annales de biologie clinique

authors： Szmidt-Adjidé V,Vanhille P

更新日期：2008-07-01 00:00:00

abstract：:Biermer's disease is an autoimmune atrophic gastritis of the fundus predominantly responsible for a malabsorption of vitamin B12. Despite its association with several autoimmune disorders, few observations have reported an association with autoimmune hemolytic anemia (AIHA). We report a case of Biermer's disease assoc...

journal_title：Annales de biologie clinique

authors： Nafil H,Tazi I,Mahmal L

更新日期：2012-07-01 00:00:00

abstract：:Our data suggest that the hyperhomocysteinemia and/or increased plasma level of lipoprotein Lp(a) are risk factors for coronary heart disease. We investigated 178 patients who underwent complete cardiac examination comprising coronary angiography and biological analysis (CT, HDL-c, LDL-c, TG, and apoAI, apoB, homocyst...

journal_title：Annales de biologie clinique

authors： Laraqui A,Bennouar N,Meggouh F,Allami A,El Kadiri N,Benkouka F,Azeddoug H,El Haitem N,Benomar A,Fellat S,Benomar M

更新日期：2002-09-01 00:00:00

abstract：:This study aims to investigate the prevalence of obesity and overweight and their association with lipid parameters in bipolar patients. Our study included 130 patients with bipolar disorder and 130 control subjects aged respectively 37.9 +/- 12.1 and 37.2 +/- 13.1 years. Obesity was evaluated by body mass index (BMI)...

journal_title：Annales de biologie clinique

authors： Ezzaher A,Haj Mouhamed D,Mechri A,Neffati F,Douki W,Gaha L,Najjar MF

更新日期：2010-05-01 00:00:00

abstract：:We report a turbidimetric procedure, using commercially available reagents, for the determination of plasma fibronectin with an unmodified centrifugal analyser. Fixed-time kinetic readings at 340 nm were taken at 60 and 720 s. A wide range of concentration (up to 1000 mg/l) can be measured. Precision and accuracy were...

journal_title：Annales de biologie clinique

authors： Hamel G,Toazara DJ,Mark J

更新日期：1982-01-01 00:00:00

abstract：:Glycated hemoglobin can be assayed by methods using different principles, whose performances vary and are difficult to control. The most widely used techniques measure either specifically glycated A1c hemoglobin (HbA1c) or total glycated hemoglobin. They are reviewed in detail in this paper and standardization problem...

journal_title：Annales de biologie clinique

authors： Gillery P,Guillemin C,Delpech M

更新日期：1994-01-01 00:00:00

abstract：:Immunoassay quantitation of human antibody depends on the availability of reference sera that have been characterized in terms of their antibody content. This report expands upon the concept of "cross-calibration", using reference (dose-response) curves that have been generated with heterologous antibody as a means of...

journal_title：Annales de biologie clinique

authors： Hamilton RG

更新日期：1991-01-01 00:00:00

abstract：:Exploring coagulation in newborns and children is a challenge due to the low levels of both procoagulant factors and inhibitors. Conventional coagulation tests might be inadequate to explore all of these changes. The aim of the study is to evaluate the thrombin generation assay, a global test to explore coagulation, i...

journal_title：Annales de biologie clinique

authors： Talon L,Sapin AF,Fourneyron V,Senectaire S,Tardieu M,Tillier M,Trapani A,Trayaud A,Vaissade A,Lebreton A,Sinegre T

更新日期：2020-12-01 00:00:00

abstract：:Li Fraumeni Syndrome (LFS) is a rare autosomal disorder characterized by a familial clustering of tumors. Analysis of several series of LFS families have shown that 70% of such families are attributable to germ-line mutations in TP53. We report the case of a patient who had a first degree family antecedent of cancer i...

journal_title：Annales de biologie clinique

authors： Landolsi S,Gharbi O,Zrig M,Gribaa M,Njim L,Zakhama A,Abid A,Frébourg T,Ahmed SB

更新日期：2010-05-01 00:00:00

abstract：:Serum carbohydrate-deficient-transferrin (CDT) was measured by a micro anion-exchange chromatography/enzyme immunoassay. Results obtained on 245 sera analyzed in four laboratories were compared. Moreover, one laboratory used a commercial kit with ready-to-use microcolumns and a radioimmunoassay for measuring eluted CD...

journal_title：Annales de biologie clinique

authors： Vernet M,Renversez JC,Revenant MC,Sotta C,charlier De Bressing C,Benoit MO,Guillemin C,Paris M,Plomteux G

更新日期：1994-01-01 00:00:00

abstract：:To validate the use of the i-STAT portable point-of-care instrument, performance checks have been conducted to verify its accuracy for PCO2/PO2 (tonometry) and precision for pH/PCO2/PO2 (control solutions). Results obtained with the i-STAT (pH/PCO2/PO2/Hct) were also compared to those provided by the Bayer Rapidlab 86...

journal_title：Annales de biologie clinique

authors： Feuillu A,Morel I,Mollard JF

更新日期：2002-03-01 00:00:00