Abstract：
:It is often reminded that if the ionized calcium is not measured, the interpretation of total calcemia should consider serum albumin. Two formulas are usually employed: ["Corrected" Ca (mmol/L) = Ca measured (mmol/L) + 0.020 or 0.025 (40 - albumin (g/L))]. This adjustment formula arises from works of Payne published in 1973. In a control population, we established the median values of calcium, albumin and ionized calcium (corrected to pH 7.40), respectively 2.34 mmol/L, 45.7 g/L and 1.23 mmol/L with our laboratory's methods (albumin - bromocresol green and Ca - ortho-cresolphtalein on a Modular analyser, Roche Diagnostics; ionized calcium with ion-selective electrode, Radiometer SA). Based on this, we retrospectively compared for 71 patients who do not belong to the control population the "corrected calcium" resulting from the two formulas and the measured calcemia to the ionized calcium corrected at pH 7,40. This comparison shows that in our laboratory, the two formulas lead to a rising underestimation of the calcium for albumin values greater than 40 g/L, reaching -0,20 mmol/L for albumin values above 44 g/L. The use of this formulas may also mask an hypercalcemia, indeed half of our patients' hypercalcemia (ionised Ca ((pH 7,40)) > 1,29 mmol/L) is not found. These results agree with Payne's recommendations for the use of his adjustment formula: the clinically justified adjustment of a low calcemia due to an hypoalbuminemia should not be extended to other situations, particularly when albumin is increased.
journal_name
Ann Biol Clin (Paris)journal_title
Annales de biologie cliniqueauthors
Parent X,Spielmann C,Hanser AMdoi
10.1684/abc.2009.0348subject
Has Abstractpub_date
2009-07-01 00:00:00pages
411-8issue
4eissn
0003-3898issn
1950-6112pii
abc.2009.0348journal_volume
67pub_type
杂志文章abstract：:In order to increase the versatility of phage display technology, it is desirable to be able to impose some structural constraints on the peptides that are presented by the phage particles. This is currently not feasible since the conformation of the capsid proteins, used to link the foreign peptide to the phage, are ...
journal_title：Annales de biologie clinique
pub_type： 共识发展会议,杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
abstract：:Premature rupture of the membranes (PROM) is a frequent event affecting 3% of pregnancies. PROM causes 30% of premature deliveries and 20% of perinatal mortality. The diagnosis relies mainly on the clinical visualization of the amniotic fluid flow in the vagina. If not, clinicians can use bedside tests detecting eithe...
journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：10.1684/abc.2018.1346
更新日期：2018-06-01 00:00:00
abstract：:Lipid profile is often performed on heparinized-plasma because nothing in particular is explained in the technical data sheet about anticoagulant and because few data (mainly with EDTA anticoagulant) are available in literature. In order to evaluate heparinized-plasma vs serum differences, 50 normo- or hyperlipidemic ...
journal_title：Annales de biologie clinique
pub_type： 杂志文章,多中心研究
doi：
更新日期：2004-09-01 00:00:00
abstract：:Gas-liquid chromatography has been used directly on clinical specimens as a method for presumptive diagnosis of anaerobic infections. This technique proved to be valuable and reliable. Combined with a Gram stain, it offers the possibility to differentiate in less than 1 hour aerobic from anaerobic infections by means ...
journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:In our societies, the increase of the frequency of the diseases of overweight, in particular obesity, diabetes type 2 and metabolic syndrome, coincides with that of the urinary lithiasis. Like the lithiasic disease, the metabolic syndrome or syndrome X is multi-factor. Several epidemiological studies were interested i...
journal_title：Annales de biologie clinique
pub_type： 杂志文章,评审
doi：10.1684/abc.2008.0187
更新日期：2008-01-01 00:00:00
abstract：:Hormonal production of the thyroid gland is constituted of thyroxine or T4 (80%) and triiodothyronine or T3 (20%). In the circulation, whole T4 originates from thyroid secretion but most of T3 (80%) is produced extrathyroidally from T4 deiodination. Conversion of T4 to T3 may be influenced by various conditions and ci...
journal_title：Annales de biologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：2003-07-01 00:00:00
abstract：:The aim of this study was to evaluate the automated urine test strip analyzer Aution Max AX 4280 which uses strips able to measure 12 urinary parameters. For precision study, we considered glucose, protein, blood, leukocytes, nitrite, and pH and the four first were compared with usual methods: chemical measurement or ...
journal_title：Annales de biologie clinique
pub_type： 临床试验,杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：:The present importance of streptococcal pathology implicates the identification of the streptococcal groups. The authors have carried out a comparative study of the various methods of extraction of the group specific antigen. They demonstrated the advantages and disadvantages of each method and consider the pronase ex...
journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：BACKGROUND:probiotic agents are increasingly used as over the counter drugs for the treatment of a variety of inflammatory and infectious conditions. The rationale of their use seems to restore a friendly bacterial flora in the gut. Complications of probiotic use, although rarely reported, can occur. OBSERVATION:we de...
journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：10.1684/abc.2008.0210
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：2005-09-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：10.1684/abc.2011.0598
更新日期：2011-07-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
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journal_title：Annales de biologie clinique
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doi：
更新日期：1983-01-01 00:00:00
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journal_title：Annales de biologie clinique
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doi：
更新日期：1991-01-01 00:00:00
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journal_title：Annales de biologie clinique
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更新日期：1990-01-01 00:00:00
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journal_title：Annales de biologie clinique
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doi：
更新日期：1985-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：10.1684/abc.2016.1174
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
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journal_title：Annales de biologie clinique
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
