Effects of diltiazem on postextrasystolic potentiation in coronary heart disease patients.

abstract：:Cardiac beta-adrenoceptor density and subtype distribution has been determined in different kinds of heart failure. A decrease in cardiac beta-adrenoceptor function appears to be a general phenomenon in all kinds of heart failure. However, cardiac beta 1- and beta 2-adrenoceptors seem to be differentially affected in ...

journal_title：European heart journal

authors： Brodde OE,Zerkowski HR,Borst HG,Maier W,Michel MC

更新日期：1989-06-01 00:00:00

abstract：AIMS:microRNA (miRNA) is reported to be present in the blood of humans and has been increasingly suggested as a biomarker for diseases. We aim to determine the potential of cardiac-specific miRNAs in circulation to serve as biomarkers for acute myocardial infarction (AMI). METHODS AND RESULTS:By verifying their tissue...

journal_title：European heart journal

authors： Wang GK,Zhu JQ,Zhang JT,Li Q,Li Y,He J,Qin YW,Jing Q

更新日期：2010-03-01 00:00:00

abstract：:In atrial flutter, chemical conversion with class I drugs is often unsuccessful, whereas class III drugs seem more promising. The different electrophysiological effects of these drugs may explain this discrepancy. To date, only experimental data show the differential effects of these drugs on conversion rate and atria...

journal_title：European heart journal

authors： Crijns HJ,Van Gelder IC,Kingma JH,Dunselman PH,Gosselink AT,Lie KI

更新日期：1994-10-01 00:00:00

abstract：AIMS:This study investigated whether sedentary behaviour and different activity levels have an independent association with carotid intima-media thickness (IMT) and with the 3-year IMT progression in different carotid segments. METHODS AND RESULTS:The study population included 614 healthy men and women (mean age = 44 ...

journal_title：European heart journal

authors： Kozàkovà M,Palombo C,Morizzo C,Nolan JJ,Konrad T,Balkau B,RISC Investigators.

更新日期：2010-06-01 00:00:00

abstract：AIMS:We designed this study in order to determine the effect of insulin on cardiac function in overweight and obese subjects during exercise. METHODS AND RESULTS:The cardiac function of 62 normal glucose tolerant subjects, aged 30-40 and divided into normal weight (group 1, n=22, BMI 20-24.9 kg/m(2)), overweight (grou...

journal_title：European heart journal

authors： Sasso FC,Carbonara O,Nasti R,Marfella R,Esposito K,Rambaldi P,Mansi L,Salvatore T,Torella R,Cozzolino D

更新日期：2005-06-01 00:00:00

abstract：AIMS:The role of aspirin in the primary prevention setting is continuously evolving. Recent randomized trials have challenged the role of aspirin in the primary prevention setting. METHODS AND RESULTS:Electronic databases were searched for randomized trials that compared aspirin vs. placebo (or control) in subjects wi...

journal_title：European heart journal

authors： Mahmoud AN,Gad MM,Elgendy AY,Elgendy IY,Bavry AA

更新日期：2019-02-14 00:00:00

abstract：:The purpose of this study was to compare rubidium-82 PET with thallium-201 SPECT imaging in 150 patients. Both techniques followed a single dipyridamole-handgrip stress, and images were displayed using the same 3-dimensional format and quantitative colour scale. Coronary arteriography was employed to assign the correc...

journal_title：European heart journal

authors： Marwick TH,Go RT,MacIntyre WJ,Saha GB,Underwood DA

更新日期：1991-10-01 00:00:00

abstract：AIMS:Induced pluripotent stem cells (iPSCs) provide a unique opportunity for the generation of patient-specific cells for use in disease modelling, drug screening, and regenerative medicine. The aim of this study was to compare human-induced pluripotent stem cells (hiPSCs) derived from different somatic cell sources re...

journal_title：European heart journal

authors： Streckfuss-Bömeke K,Wolf F,Azizian A,Stauske M,Tiburcy M,Wagner S,Hübscher D,Dressel R,Chen S,Jende J,Wulf G,Lorenz V,Schön MP,Maier LS,Zimmermann WH,Hasenfuss G,Guan K

更新日期：2013-09-01 00:00:00

abstract：AIMS:Midwall myocardial fibrosis on cardiovascular magnetic resonance (CMR) is a marker of early ventricular decompensation and adverse outcomes in aortic stenosis (AS). We aimed to develop and validate a novel clinical score using variables associated with midwall fibrosis. METHODS AND RESULTS:One hundred forty-seven...

journal_title：European heart journal

authors： Chin CW,Messika-Zeitoun D,Shah AS,Lefevre G,Bailleul S,Yeung EN,Koo M,Mirsadraee S,Mathieu T,Semple SI,Mills NL,Vahanian A,Newby DE,Dweck MR

更新日期：2016-02-21 00:00:00

abstract：:Increased sympathetic tone is found in about 30% of patients with hypertension. This abnormality is closely associated with the metabolic syndrome of dyslipidaemia and hyperinsulinaemia. In this short review we discuss the mechanisms by which sympathetic over-activity could cause the metabolic syndrome. Sympathetic st...

journal_title：European heart journal

authors： Julius S

更新日期：1998-06-01 00:00:00

abstract：:Among 369 patients with native valve infective endocarditis observed during a 14-year period, 17 were related to S: pneumoniae. Fourteen of them were observed in the last 7 years. At the time of admission 13 exhibited purulent meningitis, 6 of them being comatose. An apparent portal of entry was present in 13 patients...

journal_title：European heart journal

authors： Wolff M,Regnier B,Witchitz S,Gibert C,Amoudry C,Vachon F

更新日期：1984-10-01 00:00:00

abstract：Aims:Epidemiological studies strongly suggest a link between stress, depression, and cardiovascular diseases (CVDs); the mechanistic correlation, however, is poorly understood. A single-nucleotide polymorphism in the BDNF gene (BDNFVal66Met), associated with depression and anxiety, has been proposed as a genetic risk f...

journal_title：European heart journal

authors： Amadio P,Colombo GI,Tarantino E,Gianellini S,Ieraci A,Brioschi M,Banfi C,Werba JP,Parolari A,Lee FS,Tremoli E,Barbieri SS

更新日期：2017-05-07 00:00:00

abstract：:Chronic increases in haemodynamic load modify the expression of cardiac genes, leading to a new phenotype better adapted to the new functional demand. Several mechanisms such as the global activation of genes, the modulation of single genes and/or differential expression of multigene families may account for these mod...

journal_title：European heart journal

authors： Samuel JL,Dubus I,Contard F,Schwartz K,Rappaport L

更新日期：1990-11-01 00:00:00

abstract：:The endothelins are a family of three widely expressed 21 amino acid peptides. Apart from the ability to constrict vascular smooth muscle, they have numerous other potent effects, from enhancing mitogenesis to influencing nervous function. The pathway of their production involves the initial synthesis of a predominant...

journal_title：European heart journal

authors： Warner TD

更新日期：1993-11-01 00:00:00

abstract：AIMS:To assess the long-term benefit-risk ratio of drug-eluting (DES) vs. bare-metal stents (BMS) relative to stent size. METHODS AND RESULTS:All 826 consecutive BASKET (BAsel Stent Kosten-Effektivitäts Trial) patients randomized 2:1 to DES vs. BMS were followed after 3 years. Data were analysed separately for patient...

journal_title：European heart journal

authors： Pfisterer M,Brunner-La Rocca HP,Rickenbacher P,Hunziker P,Mueller C,Nietlispach F,Leibundgut G,Bader F,Kaiser C,BASKET.

更新日期：2009-01-01 00:00:00

abstract：:Supraventricular tachycardia is due to altered automaticity, triggered activity or most commonly, reentry. Atrial flutter is most frequently due to reentry with counterclockwise activation in the right atrium with the left atrium acting as a bystander. The small wavefronts demonstrated during atrial fibrillation are l...

journal_title：European heart journal

authors： Shakespeare CF,Anderson M,Camm AJ

更新日期：1993-09-01 00:00:00

abstract：AIMS:The SHould we emergently revascularize Occluded Coronaries in cardiogenic shocK (SHOCK) Trial showed no benefit of early revascularization in patients aged >/=75 years with acute myocardial infarction and cardiogenic shock. We examined the effect of age on treatment and outcomes of patients with cardiogenic shock ...

journal_title：European heart journal

authors： Dzavik V,Sleeper LA,Cocke TP,Moscucci M,Saucedo J,Hosat S,Jiang X,Slater J,LeJemtel T,Hochman JS,SHOCK Investigators.

更新日期：2003-05-01 00:00:00

abstract：AIMS:Clonal haematopoiesis of indeterminate potential (CHIP), defined as the presence of an expanded somatic blood cell clone without other haematological abnormalities, was recently shown to increase with age and is associated with coronary artery disease and calcification. The most commonly mutated CHIP genes, DNMT3A...

journal_title：European heart journal

authors： Mas-Peiro S,Hoffmann J,Fichtlscherer S,Dorsheimer L,Rieger MA,Dimmeler S,Vasa-Nicotera M,Zeiher AM

更新日期：2020-02-21 00:00:00

abstract：:Since fatty acids provide the majority of myocardial energy requirements under basal conditions, an alteration in the global or regional utilization of these substrates may be an early indicator of myocardial disease. To determine areas of potential clinical utility of fatty acid imaging, we synthesized a radioiodinat...

journal_title：European heart journal

authors： Livni E,Elmaleh DR,Barlai-Kovach MM,Goodman MM,Knapp FF Jr,Strauss HW

更新日期：1985-08-01 00:00:00

abstract：:A recent report of the EuroHeart project has shown that women are still underrepresented in many cardiovascular clinical trials, while important gender differences are present within most areas of heart disease. As the burden of cardiovascular disease is increasing in middle-aged women relative to men, a more profound...

journal_title：European heart journal

authors： Maas AH,van der Schouw YT,Regitz-Zagrosek V,Swahn E,Appelman YE,Pasterkamp G,Ten Cate H,Nilsson PM,Huisman MV,Stam HC,Eizema K,Stramba-Badiale M

更新日期：2011-06-01 00:00:00

abstract：:Scandinavian Cardiovascular Journal began as a journal for cardiothoracic surgery, but joining forces with cardiology has increased the impact factor and number of subscribers. ...

journal_title：European heart journal

authors： Taylor J

更新日期：2012-09-01 00:00:00

abstract：AIMS:Women, particularly younger women, hospitalized with acute myocardial infarction have been found to have poorer prognosis than men. A large proportion of deaths due to myocardial infarction, however, occur in the pre-hospital phase. We set out to analyse age-specific sex differences in survival after myocardial in...

journal_title：European heart journal

authors： Rosengren A,Spetz CL,Köster M,Hammar N,Alfredsson L,Rosén M

更新日期：2001-02-01 00:00:00

abstract：:We have determined the effects of the acute administration of intravenous (i.v.) digitalis administration (0.8 mg of digoxin in 5-10 min) on the electrophysiological variables of 12 normal subjects (group 1), 12 patients with asymptomatic sinus node bradycardia (group 2) and 34 patients with symptomatic sinus node dys...

journal_title：European heart journal

authors： Bolognesi R,Benedini G,Ferrari R,Visioli O

更新日期：1986-04-01 00:00:00

abstract：AIMS:Prospective studies indicate that apolipoprotein measurements predict coronary heart disease (CHD) risk; however, evidence is conflicting, especially in the US. Our aim was to assess whether measurements of apolipoprotein B (apoB) and apolipoprotein A-I (apoA-I) can improve the ability to predict CHD death beyond ...

journal_title：European heart journal

authors： Sierra-Johnson J,Fisher RM,Romero-Corral A,Somers VK,Lopez-Jimenez F,Ohrvik J,Walldius G,Hellenius ML,Hamsten A

更新日期：2009-03-01 00:00:00

abstract：:Thrombolytic therapy is a practical, effective approach to the management of acute myocardial infarction that is widely used in Europe today. Early European trials demonstrated a clear reduction in mortality in patients who received thrombolytic therapy compared with those given conventional treatment. The findings of...

journal_title：European heart journal

authors： Vahanian A

更新日期：1996-09-01 00:00:00

abstract：Aims:The aim of this study is to develop models to aid the decision to prolong dual antiplatelet therapy (DAPT) that requires balancing an individual patient's potential benefits and harms. Methods and results:Using population-based electronic health records (EHRs) (CALIBER, England, 2000-10), of patients evaluated 1 ...

journal_title：European heart journal

authors： Pasea L,Chung SC,Pujades-Rodriguez M,Moayyeri A,Denaxas S,Fox KAA,Wallentin L,Pocock SJ,Timmis A,Banerjee A,Patel R,Hemingway H

更新日期：2017-04-07 00:00:00

abstract：:The primary success rate and incidence of major complications have been retrospectively assessed in a consecutive series of 224 patients undergoing percutaneous transluminal coronary angioplasty (PTCA) in one centre. The patients have been divided into three groups; those with angina and no previous myocardial infarct...

journal_title：European heart journal

authors： Perry RA,Seth A,Singh A,Shiu MF

更新日期：1988-01-01 00:00:00

abstract：:The magnitude and biological relevance in vivo of the beta-blocking properties, observed in vitro, of propafenone remains controversial. We studied the effects of propafenone on the heart rate response to graded stimulation of the right stellate ganglion in 13 anaesthetized, vagotomized cats. The decentralized ganglio...

journal_title：European heart journal

authors： Malfatto G,Pessano P,Zaza A,Schwartz PJ

更新日期：1993-09-01 00:00:00

abstract：:Recently published epidemiological and genetic studies strongly suggest a causal relationship of elevated concentrations of lipoprotein (a) [Lp(a)] with cardiovascular disease (CVD), independent of low-density lipoproteins (LDLs), reduced high density lipoproteins (HDL), and other traditional CVD risk factors. The ath...

journal_title：European heart journal

authors： Kostner KM,März W,Kostner GM

更新日期：2013-11-01 00:00:00

abstract：:Approximately 20% of patients undergoing diagnostic coronary arteriography for acute or chronic cardiac ischaemia have angiographically normal coronary arteries. The mechanism behind this phenomenon is likely to be the result of a combination of functional or anatomical abnormalities in the coronary microcirculation, ...

journal_title：European heart journal

authors： Chierchia SL,Fragasso G

更新日期：1996-12-01 00:00:00