Programming effects of glucocorticoids.

abstract：:In our proof-of-concept study of 1 patient with stage IIIC carcinosarcoma of the ovary, we discovered a rare mutation in the tumor suppressor, TP53, that results in the deletion of N131. Immunofluorescence imaging of the organoid culture revealed hyperstaining of p53 protein. Computational modeling suggests this resid...

journal_title：Clinical obstetrics and gynecology

authors： Bi J,Thiel KW,Litman JM,Zhang Y,Devor EJ,Newtson AM,Schnieders MJ,Gonzalez Bosquet J,Leslie KK

更新日期：2020-03-01 00:00:00

abstract：:Medical methods for pregnancy termination in early gestation offer women an alternative to surgical evacuation and have the potential to improve access globally to safe abortion. Several drug regimens are used with varying efficacy including mifepristone plus misoprostol, misoprostol alone, and methotrexate plus misop...

journal_title：Clinical obstetrics and gynecology

authors： Bartz D,Goldberg A

更新日期：2009-06-01 00:00:00

abstract：:Physicians and other health care providers requesting dual-energy x-ray bone density studies must be able to critically review and interpret such studies. This requires an understanding of the computerized result components of the studies and how such data can be applied in clinical practice. The timing and interpreta...

journal_title：Clinical obstetrics and gynecology

authors： Bonnick SL

更新日期：2013-12-01 00:00:00

abstract：:The UK Confidential Enquiry into Maternal Deaths has been in operation for more than 60 years, during which time maternal mortality rates have fallen 10-fold. The program includes two aspects, surveillance and confidential case review, providing different information to aid quality improvement in maternity care. The e...

journal_title：Clinical obstetrics and gynecology

authors： Knight M,Tuffnell D

更新日期：2018-06-01 00:00:00

abstract：:The use of mesh and graft in pelvic reconstructive surgery has increased over the last decade. As the use of these products increased, the frequency and complexity of mesh-related complications has also increased. Management of complications resulting from mesh placement requires a thoughtful, systematic approach. Alt...

journal_title：Clinical obstetrics and gynecology

authors： Barber MD

更新日期：2013-06-01 00:00:00

abstract：:The process of genetic screening has evolved from a simple notation of maternal age to a complex algorithm incorporating age, maternal serum screening, and sonographic findings. The extent to which each of these variables should contribute to the overall screening result is much debated and deserves continued research...

journal_title：Clinical obstetrics and gynecology

authors： Hawk AF,Saller DN

更新日期：2012-03-01 00:00:00

abstract：:Serous tubal intraepithelial carcinoma is considered the precursor lesion of high-grade serous carcinoma, and found in both low-risk and high-risk populations. Isolated serous tubal intraepithelial carcinomas in patients with BRCA1/2 mutations are detected in ∼2% of patients undergoing risk-reducing bilateral salpingo...

journal_title：Clinical obstetrics and gynecology

authors： Patrono MG,Corzo C,Iniesta M,Ramirez PT

更新日期：2017-12-01 00:00:00

abstract：:Because it is known that antibiotics given to the mother may reach and affect the fetus, when prescribing antibiotics during pregnancy, one must take into consideration both maternal and fetal well-being. Therapy should be directed toward the maternal disease but also be safe for the fetus. The volume of distribution ...

journal_title：Clinical obstetrics and gynecology

authors： Hedstrom S,Martens MG

更新日期：1993-12-01 00:00:00

abstract：:Both CT and MRI may play an important role in the initial assessment and subsequent management of patients with gynecologic cancer. The different capabilities of these examinations make the choice of test dependent on what portion of the body is visualized (e.g., chest, upper abdomen, or pelvis) and what information i...

journal_title：Clinical obstetrics and gynecology

authors： Russell AH,Anderson M,Walter J,Kinney W,Smith L,Scudder S

更新日期：1992-03-01 00:00:00

abstract：:Counseling regarding the options for aneuploidy risk assessment is complicated and requires thorough counseling with the patient. Second trimester serum risk assessment has been the gold standard because of widespread availability, low cost, and vast experience with counseling and performance. First trimester risk ass...

journal_title：Clinical obstetrics and gynecology

authors： Reddy UM,Wapner RJ

更新日期：2007-06-01 00:00:00

abstract：:Cardiac arrest is a rare event during pregnancy. The pregnant population represents a unique subset of cardiac arrest victims. Not only are there unique causes of circulatory collapse during the pregnant state, but the physiological modifications to the maternal physiology during pregnancy require specific modificatio...

journal_title：Clinical obstetrics and gynecology

authors： Montufar-Rueda C,Gei A

更新日期：2014-12-01 00:00:00

abstract：:In gestational diabetes (GDM), achieving euglycemia through treatment decreases the risk of adverse outcomes associated with hyperglycemia. Treatment starts with diet and nutritional counseling; however, up to 50% of women will require pharmacologic therapy to meet glucose goals. Although insulin remains the only Fede...

journal_title：Clinical obstetrics and gynecology

authors： Berggren EK,Boggess KA

更新日期：2013-12-01 00:00:00

abstract：:Predelivery diagnosis of placenta accreta, increta, and percreta (from here referred to as placenta accreta, unless otherwise noted) has increasingly created opportunities to optimize antenatal management. Despite the increased frequency of placenta accreta today, occurring in as many as 1 in 533 to 1 in 272 deliverie...

journal_title：Clinical obstetrics and gynecology

authors： Haunschild C,Yeaton-Massey A,Lyell DJ

更新日期：2018-12-01 00:00:00

abstract：:Stroke risk is 3 times higher in pregnancy than in the general young adult population and carries high morbidity and mortality risks. The recognition of signs and symptoms of stroke and other serious cerebrovascular disorders in pregnant and postpartum patients is important for the obstetrician to be able to initiate ...

journal_title：Clinical obstetrics and gynecology

authors： Barghouthi T,Bushnell C

更新日期：2018-06-01 00:00:00

abstract：:Abdominal myomectomy and hysterectomy remain the traditional treatment of large symptomatic uterine myomas. The preoperative indications for abdominal myomectomy or hysterectomy must be clearly evaluated and delineated avoid unnecessary intervention. There appears to be an increasing trend toward expectant management ...

journal_title：Clinical obstetrics and gynecology

authors： Guarnaccia MM,Rein MS

更新日期：2001-06-01 00:00:00

abstract：:The postpartum period in women with diabetes or GDM allows both the physician and mother to relax from the intensive medical and obstetric management that has permitted, in most cases, a successful and joyous outcome. The role of the physician, however, must switch to a proactive and preventive mode to formulate a rep...

journal_title：Clinical obstetrics and gynecology

authors： Kjos SL

更新日期：2000-03-01 00:00:00

abstract：:In mammalian reproductive physiology, lactation follows pregnancy; growing evidence suggests that disruption of this physiology affects a woman's lifetime risk of metabolic disease. These differences may reflect lactation-induced mobilization of fat stores and modulation of maternal stress reactivity. In addition, con...

journal_title：Clinical obstetrics and gynecology

authors： Stuebe A

更新日期：2015-12-01 00:00:00

abstract：:One in 1000 pregnancies is complicated with cancer with the most common tumors being breast cancer, cervical cancer, thyroid, leukemia, lymphoma, and ovarian cancer. It is often assumed that cancer during pregnancy necessitates sacrificing the well-being of the fetus but in most cases appropriate treatment can be offe...

journal_title：Clinical obstetrics and gynecology

authors： Brewer M,Kueck A,Runowicz CD

更新日期：2011-12-01 00:00:00

abstract：:The role of Interventional radiologic procedures for the management of suspected placenta accreta spectrum (PAS) has evolved considerably over last 3 decades. In this article, the authors describe the various techniques of vascular occlusion for the management of PAS and provide a brief review of the literature examin...

journal_title：Clinical obstetrics and gynecology

authors： Shrivastava VK,Nageotte MP

更新日期：2018-12-01 00:00:00

abstract：:Urinary tract infection in women has its origin, predominantly, via ascending bacteria from the periurethral microflora. Asymptomatic bacteriuria, except for the pregnant patient, need not be treated. E. coli is the most common bacterium to cause UTIs, and is usually susceptible to oral antibiotics. Patients who are h...

journal_title：Clinical obstetrics and gynecology

authors： Faro S,Fenner DE

更新日期：1998-09-01 00:00:00

abstract：:Pregnancy failure is defined as a lack of sonographic evidence of current or expected viability. Technologic advances in ultrasound imaging continue to redefine diagnostic criteria of pregnancy failure or success. When evaluating a pregnancy, the first step is an assessment of maternal risk factors for failure. Imagin...

journal_title：Clinical obstetrics and gynecology

authors： Canavan TP

更新日期：2017-09-01 00:00:00

abstract：:During the past decade, prophylactic doses of low-molecular-weight heparin (LMWH) have been suggested to decrease the risk of placental-mediated complications. Herein, we review the prospective randomized trials that addressed the usefulness of LMWH in preventing placental-mediated complications in high-risk women. In...

journal_title：Clinical obstetrics and gynecology

authors： Haddad B,Lecarpentier E,Touboul C,Sibai BM

更新日期：2017-03-01 00:00:00

abstract：:Ovarian neoplasms are common in women of all ages. As many as 10% of women in the United States will undergo surgical removal of an adnexal mass sometime in their lifetime. Gynecologic surgeons have pioneered laparoscopic surgery, developing what was originally a diagnostic tool into a safe and effective approach to m...

journal_title：Clinical obstetrics and gynecology

authors： Hilger WS,Magrina JF,Magtibay PM

更新日期：2006-09-01 00:00:00

abstract：:The final decision to perform a certain method of hysterectomy customarily mirrors experience and level of comfort with a particular surgical approach in the context of the patient's condition and indication for surgery. Given the morbidity and recovery associated with a laparotomic incision, every effort should be ma...

journal_title：Clinical obstetrics and gynecology

authors： Brill AI

更新日期：2006-12-01 00:00:00

abstract：:Uterine rupture is an important cause of obstetrical hemorrhage associated with morbidity for mother and fetus. Risk factors should be discussed in the counseling process. Intrapartum findings including maternal condition, fetal heart rate monitoring, and uterine activity may prove helpful in making the diagnosis of a...

journal_title：Clinical obstetrics and gynecology

authors： Lang CT,Landon MB

更新日期：2010-03-01 00:00:00

abstract：:Rectovaginal fistulas and chronic anal sphincter lacerations are uncommon complications that are most often secondary to vaginal delivery, gynecologic surgery, and inflammatory bowel disease. In this chapter, we will review the pertinent anatomy, focusing on the 6 structures that should be considered during the repair...

journal_title：Clinical obstetrics and gynecology

authors： Delancey JO,Berger MB

更新日期：2010-03-01 00:00:00

abstract：:Uterine leiomyomas pose a significant health issue to reproductive-age women. Many women desire uterine conservation, and previously safe and efficacious therapies have been limited. Magnetic resonance-guided focused ultrasound surgery is a new noninvasive therapy that has been proven to be both safe and efficacious i...

journal_title：Clinical obstetrics and gynecology

authors： Hudson SB,Stewart EA

更新日期：2008-03-01 00:00:00

abstract：:Care of the endometriosis patient today can be complex and difficult. Once medical management has been exhausted and symptoms persist patients desire further treatment options. This chapter takes an evidence-based approach at discussion of patient surgcical options for treatment of endometriosis symptoms. Surgical tec...

journal_title：Clinical obstetrics and gynecology

authors： Zanelotti A,Decherney AH

更新日期：2017-09-01 00:00:00

abstract：:Causative factors in cerebral palsy (CP) vary to some degree according to gestational age group and clinical CP subtype. Such catastrophes of birth as placental abruption, cord prolapse, and uterine rupture sharply heighten risk of CP. These conditions are fortunately uncommon, and are sometimes not survived; individu...

journal_title：Clinical obstetrics and gynecology

authors： Nelson KB

更新日期：2008-12-01 00:00:00

abstract：:Human papillomavirus (HPV) infection has been implicated in the intraepithelial cervical changes that cause most abnormal Papanicolaou smears. To date, 14 types of HPVs have been identified. All are small, nondeveloped, icosahedral DNA viruses that share a common internal antigen. In cases of cervical HPV infection...

journal_title：Clinical obstetrics and gynecology

authors： Roy M,Morin C,Casas-Cordero M,Meisels A

更新日期：1983-12-01 00:00:00