Human papillomavirus and cervical lesions.

Abstract:

:Human papillomavirus (HPV) infection has been implicated in the intraepithelial cervical changes that cause most abnormal Papanicolaou smears. To date, 14 types of HPVs have been identified. All are small, nondeveloped, icosahedral DNA viruses that share a common internal antigen. In cases of cervical HPV infection, the koilocytes and dyskeratocytes are the most frequently seen cell types. Most infections are flat aceto-white lesions. Florid condyloma acuminatum, usually detectable with the naked eye, is characterized by an irregular surface secondary to finger-like projections, in the middle of which a capillary loop comes to the surface. Spiked condyloma, not seen with the naked eye, has an irregular surface that shows asperity. 3 techniques have been used to differentiate atypical condyloma from intraepithelial neoplasia: microspectrophotometric studies, the peroxidase- antiperoxidase technique, and electronmicroscopy. There is growing evidence that papillomaviruses play an etiologic role in human genital cancer. 20-25% of dysplastic and neoplastic lesions show a coexistence of condylomas of the cervix or vulva with dysplasia or neoplasia. Epidemiologic research suggests that cervical condylomas occur at a mean age of 27.5 years, precede cervical dysplasia by 3.3 years, carcinoma in situ by 9.3 years, and invasive carcinoma by 27.4 years. The conversion of most cases of papillomas into squamous cell carcinomas requires the presence of carcinogenic initiators, 1 of which is believed to be herpes simplex virus.

journal_name

Clin Obstet Gynecol

authors

Roy M,Morin C,Casas-Cordero M,Meisels A

doi

10.1097/00003081-198312000-00019

subject

Has Abstract

pub_date

1983-12-01 00:00:00

pages

949-67

issue

4

eissn

0009-9201

issn

1532-5520

journal_volume

26

pub_type

杂志文章
  • Conservative Management of Placenta Accreta Spectrum.

    abstract::The purpose of this review was to assist obstetricians and gynecologists in considering the most appropriate conservative treatment option to manage women with placenta accreta spectrum according to their individual need and local expertise of the heath care team. The issue is challenging, as the quality of evidence w...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000395

    authors: Sentilhes L,Kayem G,Silver RM

    更新日期:2018-12-01 00:00:00

  • Surgical staging endometrial cancer.

    abstract::Nothing improves the subsequent care of a woman with endometrial cancer more than the accurate determination of the extent of her disease. A significant number of women whose malignancy is apparently confined to the uterus will have extrauterine disease after careful, complete surgical staging. The failure to detect a...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199609000-00014

    authors: Orr JW Jr,Orr PF,Taylor PT

    更新日期:1996-09-01 00:00:00

  • Medical management of ectopic pregnancy.

    abstract::In selected patients who are hemodynamically stable with an unruptured tubal pregnancy, systemic methotrexate has success rates comparable to laparoscopic salpingostomy. Larger randomized studies are necessary to adequately assess subsequent fertility. Local injection of methotrexate or other agents requires a sonogra...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199806000-00019

    authors: Namnoum AB

    更新日期:1998-06-01 00:00:00

  • New horizons in Doppler ultrasound technology: relevance for obstetrical applications.

    abstract::Technologic advances and clinical research have been extending the scope of Doppler sonography and have resulted in the emergence of new diagnostic tools that show significant promise in clinical applications. This article aims to review some of these developments that are relevant for obstetrical practice. One of the...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3181fbad5e

    authors: Maulik D,Heitmann E,Maulik D

    更新日期:2010-12-01 00:00:00

  • Reducing Maternal Mortality and Severe Maternal Morbidity Through State-based Quality Improvement Initiatives.

    abstract::State Perinatal Quality Collaboratives (PQCs) represent a major advance for scaling up quality improvement efforts for reducing maternal mortality and severe maternal morbidity. The critical roles of partners, rapid-cycle low-burden data systems, and linkage to maternal mortality review committees are reviewed. The ch...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000361

    authors: Main EK

    更新日期:2018-06-01 00:00:00

  • The modern role of reproductive surgery.

    abstract::The modern role of reproductive surgery has changed because of improved capabilities of endoscopic surgery resulting from innovation, instrumentation and experience, the development and increasing applicability of assisted reproductive technologies, and improved knowledge of the optimal application of these and other ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3182353d86

    authors: Adamson GD

    更新日期:2011-12-01 00:00:00

  • Revised FIGO staging system for endometrial cancer.

    abstract::In 1988 the International Federation of Gynecologists and Obstetricians (FIGO) developed a surgical staging system for endometrial cancer. The FIGO staging system was recently revised in 2009 to reflect our growing understanding of the natural history of endometrial cancer. In this review, we describe the revised 2009...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3182185baa

    authors: Lewin SN

    更新日期:2011-06-01 00:00:00

  • Reproductive health and genetic testing in the Third World.

    abstract::New reproductive genetics means recently developed techniques to prevent the birth of children with specific defects or genetic diseases by testing individuals for sickle cell anemia, the thalassemias, Tay-Sachs disease, cystic fibrosis, or Down syndrome. Third World health services have many deficiencies with high m...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199309000-00007

    authors: Penchaszadeh VB

    更新日期:1993-09-01 00:00:00

  • Routine ultrasound in pregnancy.

    abstract::The interest in studying routine ultrasound in pregnancy has provided useful results that can be applied to practice. There is no consistent evidence of risk caused by ultrasound, neither biologic risk for the fetus nor increased use of health services as a result of ascertained conditions. There is also no consistent...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199912000-00003

    authors: Dooley SL

    更新日期:1999-12-01 00:00:00

  • Postpartum care of the woman with diabetes.

    abstract::The postpartum period in women with diabetes or GDM allows both the physician and mother to relax from the intensive medical and obstetric management that has permitted, in most cases, a successful and joyous outcome. The role of the physician, however, must switch to a proactive and preventive mode to formulate a rep...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-200003000-00008

    authors: Kjos SL

    更新日期:2000-03-01 00:00:00

  • Current status of contraceptive steroids and the intrauterine device.

    abstract::The present status of oral contraceptive steroids and the IUD, the 2 most effective and increasingly popular contraceptive methods (used by 41.6% of all U.S. married couples practicing contraception in 1970), is presented. Oral steroid contraceptives with varying quantity and activity of estrogen (ethinyl estradiol o...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-197403000-00007

    authors: Mishell DR Jr

    更新日期:1974-03-01 00:00:00

  • Mammography, xeroradiography, and thermography.

    abstract::The concept of early breast cancer as a palpable mass with limited secondary manifestations is rapidly changing. Thanks largely to mammography, a malignant breast neoplasm can be detected long before it forms a mass. Because cure rates in this stage are high, reliable means of early detection and diagnosis are of deep...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00003081-197506000-00012

    authors: Egan RL

    更新日期:1975-06-01 00:00:00

  • Breast Cancer Posttreatment Surveillance: Diagnosis and Management of Recurrent Disease.

    abstract::There has been a steady decline in breast cancer mortality that has led to a significant increase in the number of patients surviving breast cancer. We will review in this manuscript the evidence and guidelines for posttreatment surveillance of patients with breast cancer as well as the management options for patients...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000243

    authors: Karam AK

    更新日期:2016-12-01 00:00:00

  • Surgical diseases of the breast during pregnancy.

    abstract::Physicians caring for women with diseases of the breast are well aware of the time lost before many patients consult their physicians. Nowhere is this more apparent than when a breast mass is associated with gestation or lactation. Enlargement of the breast tends to obscure parenchymal masses. Those that are found are...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00003081-198312000-00010

    authors: Canter JW,Oliver GC,Zaloudek CJ

    更新日期:1983-12-01 00:00:00

  • Subclinical thyroid dysfunction during pregnancy.

    abstract::There is compelling data and a rationale for embarking on screening to identify pregnant women with some of the multiple classes of subclinical thyroid dysfunction. However, the evidence to support such screening and treatment is lacking. Several important trials are underway or undergoing peer review that may provide...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e31822e27e3

    authors: Casey BM

    更新日期:2011-09-01 00:00:00

  • Benign breast diseases: epidemiology, evaluation, and management.

    abstract::Benign breast diseases are common and encompass a spectrum of disorders. The majority of diagnoses will stem from a patient presenting with symptoms such as a mass or discomfort, or as a result of breast imaging which shows abnormalities leading to percutaneous biopsy. When mammographic and pathologic findings are dis...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0b013e318208010e

    authors: Rungruang B,Kelley JL 3rd

    更新日期:2011-03-01 00:00:00

  • Pharmacology of oxytocin and prostaglandins.

    abstract::Significant advances have been made in the last 20 years in our knowledge about the subcellular events occurring during myometrial contractions and cervical ripening and in the mechanism of action of oxytocin and prostaglandins. These advances have been instrumental in furthering our understanding of the mechanism of ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-200009000-00006

    authors: Arias F

    更新日期:2000-09-01 00:00:00

  • Surgery and Endometriosis.

    abstract::Care of the endometriosis patient today can be complex and difficult. Once medical management has been exhausted and symptoms persist patients desire further treatment options. This chapter takes an evidence-based approach at discussion of patient surgcical options for treatment of endometriosis symptoms. Surgical tec...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000291

    authors: Zanelotti A,Decherney AH

    更新日期:2017-09-01 00:00:00

  • Expanded Preconception Carrier Screening in Clinical Practice: Review of Technology, Guidelines, Implementation Challenges, and Ethical Quandaries.

    abstract::In the last 10 years, expanded preconception carrier screening has become widely available and helps patients/couples make more informed decisions with regard to their reproductive options and facilitates more effective preconception planning, prenatal diagnosis, condition-specific counseling, and condition-specific c...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000437

    authors: Zhang T,Madeira J,Lu Y,Sun Y,Mertes H,Pennings G,Lindheim SR

    更新日期:2019-06-01 00:00:00

  • A discussion of clinical decision support services.

    abstract::The software known as Clinical Decision Support Services (CDSS) has emerged as a buzzword from the explosion of information systems within health care. CDSS is installed within a practice to provide resources and tools to support the utilization of patient data in the provider decision-making process. Additional appli...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0b013e31829cb0bf

    authors: Booker CC,Andrews PN

    更新日期:2013-09-01 00:00:00

  • The management of detrusor instability.

    abstract::Detrusor instability is a urodynamic diagnosis made when the detrusor is shown objectively to contract, spontaneously or on provocation, during the filling phase of a cystometrogram while the patient is attempting to inhibit micturition. It often is responsible for symptoms of urgency, frequency, nocturia, urge incont...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199006000-00021

    authors: Wall LL

    更新日期:1990-06-01 00:00:00

  • Comparison of first and second trimester aneuploidy risk assessment.

    abstract::Counseling regarding the options for aneuploidy risk assessment is complicated and requires thorough counseling with the patient. Second trimester serum risk assessment has been the gold standard because of widespread availability, low cost, and vast experience with counseling and performance. First trimester risk ass...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e31804c9b99

    authors: Reddy UM,Wapner RJ

    更新日期:2007-06-01 00:00:00

  • Role of clinician involvement in patient safety in obstetrics and gynecology.

    abstract::Patient safety is a significant concern for healthcare providers. Involving physicians in clinical quality activities in obstetrics and gynecology can be difficult for many reasons including time demands, lack of knowledge of process improvement activities, or change fatigue due to failure of adequate implementation o...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3181ec1b29

    authors: Mann S,Pratt S

    更新日期:2010-09-01 00:00:00

  • "How-To" Guide to Pelvic Floor Muscle Dysfunction.

    abstract::The purpose of this paper is to assist the clinician in recognizing pelvic floor muscle dysfunction in women with vulvar symptoms, to provide general treatment algorithms, and to facilitate understanding of the scientific rationale behind appropriate treatment. In short, this paper is meant to provide a "how-to" guide...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000135

    authors: Albrecht KB

    更新日期:2015-09-01 00:00:00

  • New Developments in Minimally Invasive Gynecologic Oncology Surgery.

    abstract::Minimally invasive surgery continues to transform the field of gynecologic oncology and has now become the standard of care for many early-stage malignancies. The proven benefits of minimally invasive surgery are driving the rapid introduction and dissemination of novel technologies and the increasing ability to perfo...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000286

    authors: Stewart KI,Fader AN

    更新日期:2017-06-01 00:00:00

  • Progesterone antagonists on the horizon.

    abstract::The pharmacology and potential uses of RU-486, the only anti- progesterone to reach clinical trials, including luteolytic, abortifacient, menstrual regulator, postcoital contraceptive, oral contraceptive and other uses, are reviewed. RU-486 acts on the progesterone receptors in the endometrium, specifically the decid...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-198906000-00024

    authors: Spitz IM,Bardin CW

    更新日期:1989-06-01 00:00:00

  • Renal calculi in pregnancy.

    abstract::The recent published literature dealing with urinary tract calculi during pregnancy has been summarized. Our own experience with 17 patients, (0.08% of the deliveries) in a recent 12-year interval has been described. Emphasis must be placed on the safety and limitations of renal ultrasonography. Excretory urography sh...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Horowitz E,Schmidt JD

    更新日期:1985-06-01 00:00:00

  • Caring for Opioid-dependent Pregnant Women: Prenatal and Postpartum Care Considerations.

    abstract::Pregnancy is an opportune time to identify opioid dependence, facilitate conversion to opioid maintenance treatment, and coordinate care with specialists in addiction medicine, behavioral health, and social services. Comprehensive prenatal care for opioid-dependent women involves the evaluation and the management of c...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000098

    authors: Krans EE,Cochran G,Bogen DL

    更新日期:2015-06-01 00:00:00

  • Nutrition and pregnancy.

    abstract::The importance of nutrition during pregnancy with regard to pregnancy outcome has long been acknowledged. This importance has only been further emphasized by the recent changes in food quality and availability, lifestyle changes, and a new understanding of fetal programming on adult outcomes. The impact of the recent ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e31816fda53

    authors: Mehta SH

    更新日期:2008-06-01 00:00:00

  • Other causes of fetal death.

    abstract::Although perinatal mortality rates have fallen considerably in the past several decades, the fetal component of this statistic has not decreased as rapidly as the neonatal portion. Syphilis, a significant cause of fetal death at the beginning of this century, has been eliminated and other conditions such as erythrobla...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-198706000-00010

    authors: Kochenour NK

    更新日期:1987-06-01 00:00:00