Bioelectrical impedance assessment of body composition in thyroid disease.

abstract：OBJECTIVE:Free fatty acids (FFAs) deplete the intracellular insulin stores of pancreatic beta-cells. It has been suggested that this results from a lipotoxic dysregulation of both insulin secretion and insulin synthesis. In the present study, this hypothesis was tested within a 12-h time-course by directly relating the...

journal_title：European journal of endocrinology

authors： Bollheimer LC,Kemptner DM,Kagerbauer SM,Kestler TM,Wrede CE,Buettner R

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this meta-analysis was to examine the evidence for the effectiveness of aerobic exercise interventions on reducing insulin resistance markers in obese children and/or adolescents. A secondary outcome was change in percentage of body fat. METHODS:A computerized search was made from seven databa...

journal_title：European journal of endocrinology

authors： García-Hermoso A,Saavedra JM,Escalante Y,Sánchez-López M,Martínez-Vizcaíno V

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Klotho is a lifespan-influencing gene expressed mainly in the kidneys. Soluble α-Klotho (αKL) is released into the circulation. In this study, we present baseline αKL serum levels of patients with acromegaly compared with controls with other pituitary adenomas and assess changes following transsphenoidal surg...

journal_title：European journal of endocrinology

authors： Neidert MC,Sze L,Zwimpfer C,Sarnthein J,Seifert B,Frei K,Leske H,Rushing EJ,Schmid C,Bernays RL

更新日期：2013-03-15 00:00:00

abstract：:The fast technological development, particularly single nucleotide polymorphism array, array-comparative genomic hybridization, and whole exome sequencing, has led to the discovery of many novel genetic causes of growth failure. In this review we discuss a selection of these, according to a diagnostic classification c...

journal_title：European journal of endocrinology

authors： Wit JM,Oostdijk W,Losekoot M,van Duyvenvoorde HA,Ruivenkamp CA,Kant SG

更新日期：2016-04-01 00:00:00

abstract：:Autoimmune thyroid disease is the archetype for organ-specific autoimmune disorders. Progress in treating these disorders lies in improvements of our understanding of the predisposing factors responsible, the mechanisms responsible for progression of disease, and the interaction between thyroid antigens and the immune...

journal_title：European journal of endocrinology

authors： Weetman AP

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To investigate the long-term effects of antipsychotic (AP) treatment and AP-induced hyperprolactinemia on bone mineral density (BMD) and body composition in male adolescents with autism spectrum disorders (ASDs) and/or disruptive behavior disorder (DBD). DESIGN:Physically healthy 10- to 20-year-old boys with...

journal_title：European journal of endocrinology

authors： Roke Y,van Harten PN,Buitelaar JK,Tenback DE,Quekel LG,de Rijke YB,Boot AM

更新日期：2012-12-01 00:00:00

abstract：:To study the involvement of gonadotropin-releasing hormone (GnRH) in glycosylation of circulating gonadotropin isoforms in anorexia nervosa (AN), 14 amenorrhoic patients with AN, 14 age-matched volunteers in early follicular phase, and five normal-weight re-fed patients with AN were investigated under baseline conditi...

journal_title：European journal of endocrinology

authors： Savastano S,Tommaselli AP,Valentino R,Luciano A,Gigante M,Randazzo G,Contaldo F,Scalfi L,Lombardi G

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:The evidence that stress may provoke Graves' hyperthyroidism in genetically susceptible subjects is substantial. Whether exposure to stress is related to the severity of thyrotoxicosis has not been studied. Advancing age is associated with not only less severe Graves' hyperthyroidism but also self-reported st...

journal_title：European journal of endocrinology

authors： Vos XG,Smit N,Endert E,Brosschot JF,Tijssen JG,Wiersinga WM

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to investigate whether patients with cystic fibrosis (CF) are GH resistant with increased GH release and decreased concentrations of IGF-I as a result of malabsorption, increased catabolism and impaired glucose tolerance. DESIGN:Twenty CF patients were included, ten with norm...

journal_title：European journal of endocrinology

authors： Laursen EM,Lanng S,Rasmussen MH,Koch C,Skakkebaek NE,Müller J

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of coadministered lanreotide Autogel (LA; 120  mg/month) and pegvisomant (40-120  mg/week) in acromegaly. DESIGN:This is a 28-week, multicenter, open-label, single-arm sequential study. METHODS:Patients (n=92) biochemically uncontrolled, on somatostatin analogs (SSAs) or ...

journal_title：European journal of endocrinology

authors： van der Lely AJ,Bernabeu I,Cap J,Caron P,Colao A,Marek J,Neggers S,Birman P

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Height variability is largely under genetic control, although identifying the genetic variants involved has been until recently challenging. Smallness for gestational age (SGA) is a risk factor for adult short stature. Genome-wide association studies have identified a single nucleotide polymorphism (SNP) (rs1...

journal_title：European journal of endocrinology

authors： Bouatia-Naji N,Marchand M,Cavalcanti-Proença C,Daghmoun S,Durand E,Tichet J,Marre M,Balkau B,Froguel P,Lévy-Marchal C

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:In polycystic ovary syndrome (PCOS), insulin resistance (IR) appears with high prevalence and represents the major cause of cardiometabolic complications. Lipin 1beta regulates lipid metabolism and augments insulin sensitivity. The impact of lipin 1beta expression in visceral and subcutaneous adipose tissue o...

journal_title：European journal of endocrinology

authors： Mlinar B,Pfeifer M,Vrtacnik-Bokal E,Jensterle M,Marc J

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Confirmatory testing of suspected primary aldosteronism (PA) requires an extensive medication switch that can be difficult for patients with severe complicated hypertension and/or refractory hypokalemia. For this reason, we investigated the effect of chronic antihypertensive medication on confirmatory testing...

journal_title：European journal of endocrinology

authors： Solar M,Malirova E,Ballon M,Pelouch R,Ceral J

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:IGF1 is essential for human growth and mediates its effects through the type 1 IGF receptor (IGF1R). Our objective was to determine the frequency of certain previously reported IGF1R gene variants in the normal population and their effect on stature. DESIGN:A cross-sectional study was conducted in a populati...

journal_title：European journal of endocrinology

authors： Kansra AR,Dolan LM,Martin LJ,Deka R,Chernausek SD

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Patients with craniopharyngioma are at an increased risk for cardio- and cerebrovascular mortality. The metabolic syndrome (MetS) is an important cardiometabolic risk factor, but barely studied in patients with craniopharyngioma. We aimed to investigate the prevalence of and risk factors for the MetS and its ...

journal_title：European journal of endocrinology

authors： Wijnen M,Olsson DS,van den Heuvel-Eibrink MM,Hammarstrand C,Janssen JAMJL,van der Lely AJ,Johannsson G,Neggers SJCMM

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:In men, the feedback of gonadotropins is regulated by estrogens that come from the aromatization of testosterone, but the relative contribution to the inhibition of LH and FSH secretion by the amount of locally produced estrogens within the hypothalamus and/or the pituitary, and the amount of circulating est...

journal_title：European journal of endocrinology

authors： Rochira V,Zirilli L,Genazzani AD,Balestrieri A,Aranda C,Fabre B,Antunez P,Diazzi C,Carani C,Maffei L

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:For patients who remain hypothyroid despite the administration of what would seem adequate doses of levothyroxine (L-T4), the underlying cause can be difficult to determine. The possibility of a biological cause should first be explored; however, in the majority of cases, poor adherence to medication is likel...

journal_title：European journal of endocrinology

authors： Walker JN,Shillo P,Ibbotson V,Vincent A,Karavitaki N,Weetman AP,Wass JA,Allahabadia A

更新日期：2013-05-10 00:00:00

abstract：OBJECTIVE:Although the beneficial effects of estrogen on bone are well known, the roles of estrogen receptors (ERs) in mediating these effects are not fully understood. METHODS:To study the effects of long-term ER alpha deficiency, bone phenotype was studied in aged ER alpha knockout (ERKO) mice. In addition, ERKO ost...

journal_title：European journal of endocrinology

authors： Parikka V,Peng Z,Hentunen T,Risteli J,Elo T,Väänänen HK,Härkönen P

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:Hyperthyroidism in rats produces organ hypertrophy and increases in circulating IGF-I and IGF-binding protein (IGFBP)-3. Chronic treatment with thyroxine (T(4)) during pregnancy advances parturition, blocks lactation and changes several hormone receptors in mammary gland and liver. Since IGFs are implicated i...

journal_title：European journal of endocrinology

authors： Rosato R,Lindenbergh-Kortleve D,Neck Jv,Drop S,Jahn G

更新日期：2002-05-01 00:00:00

abstract：:Objective To explore whether gestational prolactin and breast increase are markers of metabolic health in pregnancy and on long-term, in PCOS. Design Follow-up study. Women with PCOS, according to the Rotterdam criteria (n = 239), former participants of the randomized controlled trial (RCT) PregMet were invited, 131 p...

journal_title：European journal of endocrinology

authors： Underdal MO,Salvesen Ø,Schmedes A,Andersen MS,Vanky E

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Epidemiological studies suggest that hypopituitary patients have an increased risk for cardiovascular mortality. The dyslipidaemia associated with this condition is often characterised by an increase in total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol (LDL-C) and may contribute to these f...

journal_title：European journal of endocrinology

authors： Christ ER,Cummings MH,Stolinski M,Jackson N,Lumb PJ,Wierzbicki AS,Sönksen PH,Russell-Jones DL,Umpleby AM

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Glucocorticoid-induced osteoporosis is the most frequent cause of secondary osteoporosis. Nevertheless, limited data are available on bone status in patients with endogenous cortisol excess. This study is aimed at investigating the role of sex steroids and severity of hypercortisolism on bone mineral density ...

journal_title：European journal of endocrinology

authors： Tauchmanovà L,Pivonello R,De Martino MC,Rusciano A,De Leo M,Ruosi C,Mainolfi C,Lombardi G,Salvatore M,Colao A

更新日期：2007-09-01 00:00:00

abstract：:CLTA4 is relevant for FOXP3(+)Treg cells, and the link between skewed X chromosome inactivation (XCI) and autoimmunity is recognized. The observation of immune dysregulation polyendocrinopathy enteropathy X-linked syndrome and multiorgan endocrine autoimmune phenomena in various members of one family, associated with ...

journal_title：European journal of endocrinology

authors： Seidel MG,Rami B,Item C,Schober E,Zeitlhofer P,Huber WD,Heitger A,Bodamer OA,Haas OA

更新日期：2012-07-01 00:00:00

abstract：:We report on a 15-year-old girl who had presented with acute onset central diabetes insipidus at the age of 8 years; this was followed by growth failure due to acquired growth hormone deficiency. Initial magnetic resonance imaging showed a uniformly enlarged pituitary stalk and absence of posterior pituitary hyperinte...

journal_title：European journal of endocrinology

authors： Maghnie M,Genovese E,Sommaruga MG,Aricò M,Locatelli D,Arbustini E,Pezzotta S,Severi F

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:Adiponectin and resistin have been linked to inflammation, endothelial dysfunction, and/or insulin secretion or resistance. It remains to be elucidated which of these adipokines is associated primarily with biomarkers of all or only some of these categories, i.e. biomarkers of inflammation, endothelial dysfun...

journal_title：European journal of endocrinology

authors： Fargnoli JL,Sun Q,Olenczuk D,Qi L,Zhu Y,Hu FB,Mantzoros CS

更新日期：2010-02-01 00:00:00

abstract：INTRODUCTION:Patients with craniopharyngioma (CP) have disturbances of the hypothalamic-pituitary axis and serious comorbidities such as obesity. We hypothesized that the secretion of hormones regulating the nutritional status is altered in adult patients with CP compared with patients with non-functioning pituitary ad...

journal_title：European journal of endocrinology

authors： Roemmler-Zehrer J,Geigenberger V,Störmann S,Losa M,Crippa V,Otto B,Bidlingmaier M,Dimopoulou C,Stalla GK,Schopohl J

更新日期：2014-03-13 00:00:00

abstract：BACKGROUND:Adaptive alterations in maternal physiology cause changes in thyroid hormone levels throughout pregnancy, and precise biochemical evaluation is thus highly dependent on gestation-specific reference intervals and expected intra-individual variation. OBJECTIVE:The aim of the study was the assessment of the in...

journal_title：European journal of endocrinology

authors： Boas M,Forman JL,Juul A,Feldt-Rasmussen U,Skakkebaek NE,Hilsted L,Chellakooty M,Larsen T,Larsen JF,Petersen JH,Main KM

更新日期：2009-12-01 00:00:00

abstract：CONTEXT:Craniopharyngioma patients without GH therapy are at an increased cardiovascular disease (CVD) risk and particularly concerning women. No previous study on long-term GH therapy in adults with childhood onset (CO) craniopharyngioma was identified. OBJECTIVE:To investigate CVD risk in adults with CO craniopharyn...

journal_title：European journal of endocrinology

authors： Holmer H,Ekman B,Björk J,Nordstöm CH,Popovic V,Siversson A,Erfurth EM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Hyperprolactinemia has been reported to be associated with abnormalities of carbohydrate metabolism. The aim of this study was to evaluate the effects of hyperprolactinemia and bromocriptine (Brc) treatment on endothelial function, insulin sensitivity and inflammatory markers in pre-menopausal women. METHOD...

journal_title：European journal of endocrinology

authors： Yavuz D,Deyneli O,Akpinar I,Yildiz E,Gözü H,Sezgin O,Haklar G,Akalin S

更新日期：2003-09-01 00:00:00

abstract：:Effective diabetes care requires a partnership between prepared, proactive practice teams and informed, activated patients. Diabetes education helps to overcome many of the barriers to effective self-management by enabling people with diabetes to make informed decisions about their day-to-day self-care. Both psychosoc...

journal_title：European journal of endocrinology

authors： Funnell MM

更新日期：2004-10-01 00:00:00