Effect of chronic thyroxine treatment on IGF-I, IGF-II and IGF-binding protein expression in mammary gland and liver during pregnancy and early lactation in rats.

abstract：:Bone loss due to menopause, natural or artificial, has been attributed solely to low estrogen. However, in a woman's life, the most precipitous bone loss begins 2 years prior to the last menstrual period, during which time estrogen levels are unperturbed whereas FSH is elevated. Our cell-based and mouse genetic studie...

journal_title：European journal of endocrinology

authors： Iqbal J,Sun L,Zaidi M

更新日期：2010-07-01 00:00:00

abstract：:Approximately 15 million babies are born preterm across the world every year, with less than 37 completed weeks of gestation. Survival rates increased during the last decades with the improvement of neonatal care. With premature birth, babies are deprived of the intense intrauterine growth phase, and postnatal growth ...

journal_title：European journal of endocrinology

authors： Boguszewski MCDS,Cardoso-Demartini AA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Cushing's disease (CD) is usually caused by ACTH-secreting pituitary microadenomas, while silent corticotroph adenomas (SCA) are macroadenomas without Cushingoid features. However, the molecular mechanism(s) underlying their different tumor growth remains unknown. The aim of the current study was to evaluate ...

journal_title：European journal of endocrinology

authors： Tani Y,Inoshita N,Sugiyama T,Kato M,Yamada S,Shichiri M,Hirata Y

更新日期：2010-10-01 00:00:00

abstract：:Anorexia nervosa is a syndrome, that is collections of symptoms, which is not defined by its etiology. The severe cases are intractable. The syndrome is associated with multiple, profound endocrine alterations which may be adaptive, reactive or etiologic. Adaptive changes potentially may be inappropriate in clinical s...

journal_title：European journal of endocrinology

authors： Støving RK

更新日期：2019-01-01 00:00:00

abstract：:Pituitary tumours express both somatostatin and dopamine receptors. Medical treatment with somatostatin analogues is a cornerstone of GH- and TSH-secreting tumours, while treatment with dopamine agonists is a cornerstone of prolactin-secreting tumours. Dopamine agonists have also demonstrated some efficacy in patients...

journal_title：European journal of endocrinology

authors： Colao A,Filippella M,Pivonello R,Di Somma C,Faggiano A,Lombardi G

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:Chromosomal rearrangements of the RET proto-oncogene is one of the most common molecular events in papillary thyroid carcinoma (PTC). However, their pathogenic role and clinical significance are still debated. This study aimed to investigate the prevalence of RET/PTC rearrangement in a cohort of BRAF WT PTCs ...

journal_title：European journal of endocrinology

authors： Colato C,Vicentini C,Cantara S,Pedron S,Brazzarola P,Marchetti I,Di Coscio G,Chilosi M,Brunelli M,Pacini F,Ferdeghini M

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:HDLs have many diverse functions. The goal of this study was to determine the association of HDL cholesterol (HDL-C) and apolipoprotein A-I (apoA-I) with the development of type 2 diabetes (T2D). In particular, this study determined the association between the ratio of HDL-C to apoA-I (HA) and incident T2D. ...

journal_title：European journal of endocrinology

authors： Hwang YC,Ahn HY,Park SW,Park CY

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:This open label, multicentre study was designed to evaluate the efficacy and tolerability of lanreotide Autogel (L-Autogel) in acromegalic patients over a 24-week period. The outcome of treatment with this new, long-acting, aqueous formulation of lanreotide was also compared with the patients' previous treatm...

journal_title：European journal of endocrinology

authors： Alexopoulou O,Abrams P,Verhelst J,Poppe K,Velkeniers B,Abs R,Maiter D

更新日期：2004-09-01 00:00:00

abstract：:Regulatory actions of angiotensin II (AngII), which is involved in the pathophysiology of hypertension and also participates in cell proliferation and cell differentiation, are mainly mediated by AngII type 1 (AT1) receptor. Recently, activating mutations of receptors causing hyperfunctioning endocrine diseases have b...

journal_title：European journal of endocrinology

authors： Sachse R,Shao XJ,Rico A,Finckh U,Rolfs A,Reincke M,Hensen J

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:To identify chromosomal gains and losses in sporadic parathyroid adenomas (PAs). METHODS:Fourteen sporadic PAs were studied by comparative genomic hybridization (CGH). RESULTS:The fourteen studied PAs showed chromosomal imbalances. All cases except one exhibited two or more abnormalities. Chromosomal gains ...

journal_title：European journal of endocrinology

authors： Garcia JL,Tardio JC,Gutierrez NC,Gonzalez MB,Polo JR,Hernandez JM,Menarguez J

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:KLF7 encodes Krüppel-like factor (KLF) 7, a member of the KLF family of transcription factors, initially shown to play important roles in cellular development and differentiation, and reported to be specifically involved in adipogenesis. Several single nucleotide polymorphisms (SNPs) have been identified in K...

journal_title：European journal of endocrinology

authors： Zobel DP,Andreasen CH,Burgdorf KS,Andersson EA,Sandbaek A,Lauritzen T,Borch-Johnsen K,Jørgensen T,Maeda S,Nakamura Y,Eiberg H,Pedersen O,Hansen T

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Herpes simplex virus type 1 (HSV-1)-derived vectors are known to be effective tools to deliver transgenes into normal and neoplastic anterior pituitary (AP) cells in vitro. Our objective was to assess the in vitro and in vivo effects of tsK/beta-gal, a temperature-sensitive HSV-1-derived vector harbouring the...

journal_title：European journal of endocrinology

authors： Bolognani F,Albariño C,Romanowski V,Carri NG,Goya RG

更新日期：2001-10-01 00:00:00

abstract：:The control of prolactin (PRL) secretion by N-methyl-D-aspartate (NMDA) and kainic acid (KA), agonists of NMDA and kainate receptors, and the interactions between NMDA and KA with nitric oxide (NO) were analysed in prepubertal female rats. For this purpose, serum PRL concentrations and hypothalamic and pituitary dopam...

journal_title：European journal of endocrinology

authors： Pinilla L,González D,Tena-Sempere M,Aguilar R,Aguilar E

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:The first aim of this work was to investigate, under basal conditions in adult male rats, the long-term consequences of perinatal maternal food restriction on the plasma concentrations of vasopressin (VP), aldosterone and atrial natriuretic peptide (ANP) and on plasma renin activity (PRA). Furthermore, under ...

journal_title：European journal of endocrinology

authors： Sebaai N,Lesage J,Alaoui A,Dupouy JP,Deloof S

更新日期：2002-12-01 00:00:00

abstract：:Fibrous dysplasia/McCune-Albright Syndrome (FD/MAS), arising from gain-of-function mutations in Gαs, and cutaneous skeletal hypophosphatemia syndrome (CSHS), arising from gain-of-function mutations in the Ras/MAPK pathway, are strikingly complex, mosaic diseases with overlapping phenotypes. Both disorders are defined ...

journal_title：European journal of endocrinology

authors： de Castro LF,Ovejero D,Boyce AM

更新日期：2020-05-01 00:00:00

abstract：:To evaluate the effects of two regimens of recombinant human GH (rhGH) on growth, bone growth and bone mineralization in GH deficient children, we studied two groups (A and B), each including 16 GH deficient children matched for sex, age, body mass index, height, height velocity and bone age/chronological age ratio (B...

journal_title：European journal of endocrinology

authors： Radetti G,Buzi F,Paganini C,Martelli C,Adami S

更新日期：2000-01-01 00:00:00

abstract：AIM:To characterize the clinical phenotype of type 2 diabetes mellitus (T2DM) with respect to age, gender, and BMI. METHOD:Anonymized data of 120,183 people with T2DM from the German/Austrian multicenter Diabetes Patienten Verlaufsdokumentation database were analyzed based on chronological age or age at diagnosis (0-1...

journal_title：European journal of endocrinology

authors： Awa WL,Fach E,Krakow D,Welp R,Kunder J,Voll A,Zeyfang A,Wagner C,Schütt M,Boehm B,de Souza M,Holl RW,DPV Initiative.,German BMBF Competence Networks Diabetes mellitus and Obesity.

更新日期：2012-08-01 00:00:00

abstract：:The study was undertaken to investigate the interaction between the release of endothelin-1 (ET-1) and prolactin (PRL) from human decidualized endometrial cells, and the effects of transforming growth factor (TGF)-beta 1 on the release of ET-1 and PRL from human decidual cells in the early stage of pregnancy. Stromal ...

journal_title：European journal of endocrinology

authors： Kubota T,Taguchi M,Kobayashi K,Masuda M,Aso T

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:A stress reaction involving increased cortisol release, which has not been documented thus far, might affect the assessment of selectivity of catheterization during adrenal venous sampling (AVS). OBJECTIVE:To investigate whether an ACTH-driven cortisol release occurs during AVS and whether it influences the...

journal_title：European journal of endocrinology

authors： Seccia TM,Miotto D,Battistel M,Motta R,Barisa M,Maniero C,Pessina AC,Rossi GP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Survival rates among childhood cancer survivors (CCS) have enormously increased in the last 40 years. However, this improvement has been achieved at the expense of serious late effects that frequently involve the endocrine system. AIM:To evaluate the cumulative incidence of endocrine diseases in a cohort of...

journal_title：European journal of endocrinology

authors： Brignardello E,Felicetti F,Castiglione A,Chiabotto P,Corrias A,Fagioli F,Ciccone G,Boccuzzi G

更新日期：2013-02-20 00:00:00

abstract：OBJECTIVE:Changes in many gastrointestinal peptides, including the anorexigenic peptide YY (PYY), which is produced by L cells, occur in both anorexia nervosa (AN) and obesity (OB). High PYY levels are present in AN, whereas in morbid OB fasting and postprandial PYY secretion is blunted. Somatostatin (somatotropin rele...

journal_title：European journal of endocrinology

authors： Rigamonti AE,Cella SG,Bonomo SM,Mancia G,Grassi G,Perotti M,Agosti F,Sartorio A,Müller EE,Pincelli AI

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Subclinical hypothyroidism occurs in a number of children with Down's syndrome (DS). The reason for the mildly elevated plasma thyrotropin (TSH) concentrations is not known. The present study investigated whether decreased TSH bioactivity plays a role in this phenomenon. DESIGN:A retrospective study of plasm...

journal_title：European journal of endocrinology

authors： Konings CH,van Trotsenburg AS,Ris-Stalpers C,Vulsma T,Wiedijk BM,de Vijlder JJ

更新日期：2001-01-01 00:00:00

abstract：:123I-metaiodobenzylguanidine (123I-MIBG) scintigraphy scanning is commonly used in the imaging of phaeochromocytoma (and paraganglioma) to confirm the site of disease and whether any spread has occurred. However, 123I-MIBG imaging is negative in 15% of cases of benign phaeochromocytoma and around 50% of cases of malig...

journal_title：European journal of endocrinology

authors： Mackenzie IS,Gurnell M,Balan KK,Simpson H,Chatterjee K,Brown MJ

更新日期：2007-10-01 00:00:00

abstract：:Low levels of insulin-like growth factor I (IGF-I) in critical illness are observed despite increased or normal levels of growth hormone (GH). The mechanisms for this apparent GH resistance have not been elucidated. As many of the acute inflammatory responses in critical illness are mediated by the proinflammatory cyt...

journal_title：European journal of endocrinology

authors： Wolf M,Böhm S,Brand M,Kreymann G

更新日期：1996-12-01 00:00:00

abstract：:Cinacalcet HCl, an allosteric modulator of the calcium-sensing receptor (CaR), has recently been approved for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, due to its suppressive effect on parathyroid hormone (PTH) secretion. Although cinacalcet's effects in patien...

journal_title：European journal of endocrinology

authors： Kawata T,Imanishi Y,Kobayashi K,Kenko T,Wada M,Ishimura E,Miki T,Nagano N,Inaba M,Arnold A,Nishizawa Y

更新日期：2005-10-01 00:00:00

abstract：:Signalling of receptor activator of nuclear factor-κB (RANK) ligand (RANKL) through RANK is a critical pathway to regulate the differentiation and activity of osteoclasts and, hence, a master regulator of bone resorption. Increased RANKL activity has been demonstrated in diseases characterised by excessive bone loss s...

journal_title：European journal of endocrinology

authors： Tsourdi E,Rachner TD,Rauner M,Hamann C,Hofbauer LC

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Recent observational studies have established progression and recurrence rates of pituitary adenomas. However, it is still unknown how individual pituitary adenomas grow over years and whether growth kinetics follow a distinct growth model. The objective of this study was to define a growth model for non-func...

journal_title：European journal of endocrinology

authors： Honegger J,Zimmermann S,Psaras T,Petrick M,Mittelbronn M,Ernemann U,Reincke M,Dietz K

更新日期：2008-03-01 00:00:00

abstract：Objective:Several clinical studies have reported that renal impairments are sometimes observed in patients with primary aldosteronism (PA). We analyzed the prevalence of renal impairments in PA patients and identified parameters that increase the risk for them. Design:This is a retrospective cross-sectional study. We ...

journal_title：European journal of endocrinology

authors： Kawashima A,Sone M,Inagaki N,Takeda Y,Itoh H,Kurihara I,Umakoshi H,Ichijo T,Katabami T,Wada N,Ogawa Y,Kawashima J,Fujita M,Miyauchi S,Okamura S,Fukuoka T,Yanase T,Izawa S,Yoshikawa Y,Hashimoto S,Yamada M,Kai T,

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Amine precursor uptake and decarboxylation is a classical feature of gastroenteropancreatic (GEP) neuroendocrine tumors (NET). Production of catecholamines was studied in GEP NET and non-NET patients. DESIGN:A cross-sectional study was undertaken. METHODS:We studied catecholamine and metabolite secretion in...

journal_title：European journal of endocrinology

authors： Ciofu A,Baudin E,Chanson P,Cailleux AF,Comoy E,Sabourin JC,Ducreux M,Schaison G,Schlumberger M

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:TSH-secreting pituitary tumors (TSH-omas) are a rare cause of hyperthyroidism and account for <1% of all pituitary adenomas. Failure to recognize the presence of a TSH-oma may result in dramatic consequences such as thyroid ablation that may cause further growth in pituitary tumor. The primary goal of the tre...

journal_title：European journal of endocrinology

authors： Kienitz T,Quinkler M,Strasburger CJ,Ventz M

更新日期：2007-07-01 00:00:00