Induction of T helper 2 immunity to an immunodominant allopeptide.

abstract：:Since major histocompatibility (MHC) antigen matching was introduced in the early 1970s as the key factor determining kidney transplant allocation, several studies, mainly arising from organ-sharing organizations in the United States and Europe, have debated this complex issue. The first fundamental concern is the int...

journal_title：Transplantation

authors： Hiesse C,Pessione F,Houssin D

更新日期：2004-02-27 00:00:00

abstract：BACKGROUND:The liver is an immunologic privileged organ; liver allografts are accepted across major histocompatibility complex barriers in many species. However, hepatocyte transplants are acutely rejected, suggesting a role for liver nonparenchymal cells in regulating the immunoresponse. We have shown potent immunoreg...

journal_title：Transplantation

authors： Charles R,Chou HS,Wang L,Fung JJ,Lu L,Qian S

更新日期：2013-07-15 00:00:00

abstract：:Hepatic artery thrombosis is a continuing source of morbidity and mortality following orthotopic liver transplantation. The cornerstone of therapy has been urgent retransplantation that is limited by organ availability. For this reason we developed a policy of urgent revascularization for allograft rescue. Hepatic art...

journal_title：Transplantation

authors： Langnas AN,Marujo W,Stratta RJ,Wood RP,Li SJ,Shaw BW

更新日期：1991-01-01 00:00:00

abstract：:The class II region of major histocompatibility complex of the rat. Rattus norvegicus (RT1) consists of RT1.B, RT1.D, and RT1.H subregions. The gene order around the H subregion was determined as RT1.A--H beta-H alpha--B by RFLP analysis of naturally occurring intra-RT1 recombinant rats with HLA DP probes. A unique re...

journal_title：Transplantation

authors： Fujii H,Kakinuma M,Yoshiki T,Natori T

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:The significance of late urinary tract infections (UTIs) after renal transplantation and their association with scarring and graft dysfunction remains controversial. We sought to define the prevalence of renal scarring in allograft recipients with a history of late recurrent UTIs, to determine whether the pr...

journal_title：Transplantation

authors： Dupont PJ,Psimenou E,Lord R,Buscombe JR,Hilson AJ,Sweny P

更新日期：2007-08-15 00:00:00

abstract：OBJECTIVES:To retrospectively compare the accuracy of pretransplant panel of reactivity antibodies (PRA) and serum level of soluble CD30 (sCD30) in predicting early (< 6 months) acute rejection (AR) in living-donor and deceased-donor kidney-transplant (KT) patients. METHODS:Pretransplant sera of 24 KT recipients were ...

journal_title：Transplantation

authors： Cinti P,Pretagostini R,Arpino A,Tamburro ML,Mengasini S,Lattanzi R,De Simone P,Berloco P,Molajoni ER

更新日期：2005-03-15 00:00:00

abstract：:Pulmonary complications are often lethal components of acute graft-vs.-host disease (GVHD). Although interstitial pneumonitis and lymphocytic bronchitis have been implicated as elements of acute GVHD, previous studies have not determined a correlation between the onset of these histopathologies or their contribution t...

journal_title：Transplantation

authors： Workman DL,Clancy J Jr

更新日期：1994-07-27 00:00:00

abstract：BACKGROUND:The authors investigated the cognitive status during the late postoperative phase in children who had undergone liver transplantation (LTx). METHODS:The authors examined 44 children who had undergone liver transplantation at their center. The children were 8.9+/-2.3 (mean+/-SD) years of age and had received...

journal_title：Transplantation

authors： Kaller T,Schulz KH,Sander K,Boeck A,Rogiers X,Burdelski M

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:Immunosuppression in renal transplantation, although manageable in the short-term, is a major hurdle for long-term graft survival. Recently, increased frequencies of CD4CD25 regulatory T cells (Tregs) have been described as an additional mechanism that induces alloimmune tolerance. METHODS:We assessed 64 re...

journal_title：Transplantation

authors： Segundo DS,Ruiz JC,Izquierdo M,Fernández-Fresnedo G,Gómez-Alamillo C,Merino R,Benito MJ,Cacho E,Rodrigo E,Palomar R,López-Hoyos M,Arias M

更新日期：2006-08-27 00:00:00

abstract：BACKGROUND:Neuromuscular blockade (NMB) reversal with neostigmine and glycopyrrolate has been reported to cause cardiac arrest in patients with a history of cardiac transplantation. The purpose of this study was to examine the safety of NMB reversal with acetylcholinesterase inhibitors and muscarinic anticholinergics i...

journal_title：Transplantation

authors： Barbara DW,Christensen JM,Mauermann WJ,Dearani JA,Hyder JA

更新日期：2016-12-01 00:00:00

abstract：:The individual effects of verapamil and 2 antioxidants on perfused rat liver nucleoside triphosphate (NTP) recovery following cold storage in University of Wisconsin (UW) solution was assessed using 31P nuclear magnetic resonance spectroscopy. The pharmacological agents were added to UW solution and were present only ...

journal_title：Transplantation

authors： Bowers JL,Neymark E,Cook CU,Clouse ME

更新日期：1994-06-15 00:00:00

abstract：BACKGROUND:Oral ingestion of potassium dichromate produces a complex spectrum of complications. It has an extremely poor prognosis and usually leads to rapid death. METHODS:We report the case of a 16-year-old male patient who was admitted to hospital after oral ingestion of potassium dichromate with suicidal intention...

journal_title：Transplantation

authors： Stift A,Friedl J,Längle F,Berlakovich G,Steininger R,Mühlbacher F

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:To reduce the morbidity of living kidney donors we introduced ketorolac-based analgesia for patients undergoing open donor nephrectomy in August 1999. There are no prior reports on the use of ketorolac for patients undergoing donor nephrectomy. METHODS:We conducted a retrospective review of all 198 consecut...

journal_title：Transplantation

authors： Freedland SJ,Blanco-Yarosh M,Sun JC,Hale SJ,Elashoff DA,Litwin MS,Smith RB,Rajfer J,Gritsch HA

更新日期：2002-03-15 00:00:00

abstract：BACKGROUND:The urinary CXC chemokine ligand (CXCL)10 detects renal transplant inflammation noninvasively, but has limited sensitivity and specificity. In this study, we performed urinary proteomic analysis to identify novel biomarkers that may improve the diagnostic performance of urinary CXCL10 for detecting alloimmun...

journal_title：Transplantation

authors： Ho J,Rush DN,Krokhin O,Antonovici M,Gao A,Bestland J,Wiebe C,Hiebert B,Rigatto C,Gibson IW,Wilkins JA,Nickerson PW

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Sirolimus (rapamycin) is a potent immunosuppressant with a mechanism of action different from cyclosporine (CsA) or tacrolimus. METHODS:In 11 European centers, first cadaveric renal allograft recipients were randomized to CsA (n=42) or sirolimus (n=41). Dosing of these agents was concentration-controlled an...

journal_title：Transplantation

authors： Groth CG,Bäckman L,Morales JM,Calne R,Kreis H,Lang P,Touraine JL,Claesson K,Campistol JM,Durand D,Wramner L,Brattström C,Charpentier B

更新日期：1999-04-15 00:00:00

abstract：:During anesthesia 5 mg of muromonab CD3 (OKT3), an anti-CD3 monoclonal antibody, was administered prophylactically to twelve patients undergoing cadaveric renal transplantation. Preoperatively, all patients were at or near their dry body weights. Methylprednisolone 500 mg on call to or in the operating room, azathiopr...

journal_title：Transplantation

authors： Robinson ST,Barry JM,Norman DJ

更新日期：1993-08-01 00:00:00

abstract：:Thirteen renal allograft recipients (6 patients on cyclosporine/7 patients on azathioprine) participated in a short-term oral protein-loading study to determine the effect of cyclosporine on an allograft's functional reserve. The baseline glomerular filtration rate of the two groups were similar (52 +/- 18 ml/min/1.73...

journal_title：Transplantation

authors： Nunley JR,King A,Comstock T,Posner M,Marshall C,Sica DA

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:One of the alternative options to simultaneous pancreas-kidney transplantation (SPKT) for type I diabetics with renal failure is sequential transplant of a living donor kidney followed by a deceased donor pancreas transplant (pancreas after living donor kidney transplant [PALK]). We retrospectively compared ...

journal_title：Transplantation

authors： Poommipanit N,Sampaio MS,Cho Y,Young B,Shah T,Pham PT,Wilkinson A,Danovitch G,Bunnapradist S

更新日期：2010-06-27 00:00:00

abstract：BACKGROUND:Co-stimulatory blockade has been shown to prolong allograft survival in different transplant models. We investigated the effect of combining humanized anti-CD80 and anti-CD86 monoclonal antibodies (mAb) with sirolimus in cynomolgus monkey renal transplant recipients. METHODS:After renal transplantation, gro...

journal_title：Transplantation

authors： Bîrsan T,Hausen B,Higgins JP,Hubble RW,Klupp J,Stalder M,Celniker A,Friedrich S,O'Hara RM,Morris RE

更新日期：2003-06-27 00:00:00

abstract：:Islet transplantation is currently being explored as a treatment for patients with type 1 diabetes. At present, the number of patients becoming insulin-independent is rapidly increasing world-wide applying the transplantation protocol originally described by the group in Edmonton. A hallmark in this procedure is repea...

journal_title：Transplantation

authors： Korsgren O,Nilsson B,Berne C,Felldin M,Foss A,Kallen R,Lundgren T,Salmela K,Tibell A,Tufveson G

更新日期：2005-05-27 00:00:00

abstract：BACKGROUND:Hemostatic complications are not uncommon after bone marrow transplantation (BMT). However, little is known about the frequency, localization, determinants, and outcome of hemostatic events in autologous and allogeneic BMT. METHODS:Four hundred forty-seven patients (364 allogeneic, 83 autologous transplants...

journal_title：Transplantation

authors： Pihusch R,Salat C,Schmidt E,Göhring P,Pihusch M,Hiller E,Holler E,Kolb HJ

更新日期：2002-11-15 00:00:00

abstract：BACKGROUND:In the experiment described here, we investigated the effects of the immunosuppressants FK506 and leflunomide (Lef) on the survival of hamster hearts and liver xenografts in Lewis rats. METHODS:Lewis rats were used as recipients of hamster heart or liver grafts using different regimens of FK506 and Lef. Don...

journal_title：Transplantation

authors： Sankary HN,Yin DP,Chong AS,Ma LL,Blinder L,Shen JK,Foster P,Williams JW

更新日期：1998-10-15 00:00:00

abstract：BACKGROUND:Extensive third degree burn wounds can be permanently covered by the transplantation of autologous cultured keratinocytes. Many modifications to Green and colleagues' original technique have been suggested, including the use of a fibrin matrix. However, the properties of the cultured cells must be assessed u...

journal_title：Transplantation

authors： Ronfard V,Rives JM,Neveux Y,Carsin H,Barrandon Y

更新日期：2000-12-15 00:00:00

abstract：BACKGROUND:The full potential of pancreatic islet transplantation (PIT) has not been realized because of the difficulties associated with islet isolation, particularly when associated with a remote islet isolation center. Herein, we describe the principles of pancreatic procurement for PIT, which have allowed us to ach...

journal_title：Transplantation

authors： Lee TC,Barshes NR,Brunicardi FC,Alejandro R,Ricordi C,Nguyen L,Goss JA

更新日期：2004-08-15 00:00:00

abstract：:Hepatic artery thrombosis (HAT) after liver transplantation (LTx) usually mandates retransplantation. Prolonged preservation with Eurocollins solution has been associated with HAT. We reviewed our experience with 359 LTx patients to identify risk factors for HAT. All grafts were preserved in University of Wisconsin so...

journal_title：Transplantation

authors： Mor E,Schwartz ME,Sheiner PA,Menesses P,Hytiroglou P,Emre S,Kishikawa K,Chiodini S,Miller CM

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:This study investigated the use of deceased heart-beating donor livers offered for transplantation during a 10-year period, during which there has been an increasing disparity between organ supply and demand in the United Kingdom. METHODS:Summary data from the National Transplant Database were analyzed on a...

journal_title：Transplantation

authors： Devey LR,Friend PJ,Forsythe JL,Mumford LL,Wigmore SJ

更新日期：2007-07-15 00:00:00

abstract：:A model for immediate vascularization of skin was devised to examine one of the possible explanations for the differential survival rates of transplants of freely grafted skin and organs, i.e., the increased vulnerability of skin to early ischemic necrosis prior to revascularization. Female Fischer (F) rat skin was tr...

journal_title：Transplantation

authors： Perloff LJ,Barker CF

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:HLA-specific antibodies detected by solid phase assays are increasingly used to define unacceptable HLA antigen mismatches (UAM) before renal transplantation. The accuracy of this approach is unclear. METHODS:Day of transplant sera from 211 complement-dependent cytotoxicity crossmatch-negative patients were...

journal_title：Transplantation

authors： Zecher D,Bach C,Preiss A,Staudner C,Utpatel K,Evert M,Jung B,Bergler T,Böger CA,Spriewald BM,Banas B

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:Bone marrow cells expressing foreign MHC antigens survive poorly after transplantation. Stable mixed hematopoietic chimerism requires reconstitution with a relatively large number of foreign bone marrow cells and intensive depletion of host cells. In addition, when foreign MHC-transduced autologous bone ma...

journal_title：Transplantation

authors： Zhang JL,Cai J,Jackson JD,Walls S,Kuszynski CA,Fox IJ

更新日期：2005-05-27 00:00:00

abstract：:To improve long-term outcome after renal transplantation, attention should be placed on the tailored use of immunosuppressive regimens that have a more favorable impact on the immunological and nonimmunological risk profiles of an individual recipient. Tacrolimus is widely used for maintenance and rejection immunosupp...

journal_title：Transplantation

authors： First MR

更新日期：2001-09-27 00:00:00