Children and adolescents with follicular lymphoma have an excellent prognosis with either limited chemotherapy or with a "Watch and wait" strategy after complete resection.

abstract：:The appropriate management of patients with moderate aplastic anemia (mAA) remains to be unclear and controversial. A cohort of 118 patients with mAA received a novel immunosuppressive strategy of cyclosporine alternately combined with levamisole (CSA and LMS regimen), which included 42 newly diagnosed and 76 chronic ...

journal_title：Annals of hematology

authors： Li X,Shao Y,Ge M,Shi J,Huang J,Huang Z,Zhang J,Nie N,Zheng Y

更新日期：2013-09-01 00:00:00

abstract：:Extramedullary (e) relapse in multiple myeloma(MM) has an adverse prognosis, but knowledge concerning biological features and preferred treatment is scarce. We screened the myeloma registry of our institution for eMM relapses and identified 24 cases among 357 patients (pts).Only 8% of eMM relapses occurred after initi...

journal_title：Annals of hematology

authors： Rasche L,Bernard C,Topp MS,Kapp M,Duell J,Wesemeier C,Haralambieva E,Maeder U,Einsele H,Knop S

更新日期：2012-07-01 00:00:00

abstract：:Cerebrovascular disease resulting in stroke is a serious and preventable complication of sickle cell anaemia (SCA). Children at high risk of preventable stroke can be identified by transcranial Doppler ultrasound (TCD). Current guidelines in the UK recommend annual TCD screening from 3 years, although studies suggest ...

journal_title：Annals of hematology

authors： Roberts L,O'Driscoll S,Dick MC,Height SE,Deane C,Goss DE,Pohl K,Rees DC

更新日期：2009-10-01 00:00:00

abstract：:Iron deficiency anemia is among the most frequent causes of disability. Intravenous iron is the quickest way to correct iron deficiency, bypassing the bottleneck of iron intestinal absorption, the only true mechanism of iron balance regulation in human body. Intravenous iron administration is suggested in patients who...

journal_title：Annals of hematology

authors： Giordano G,Napolitano M,Di Battista V,Lucchesi A

更新日期：2020-12-02 00:00:00

abstract：:Neutral red is a vital stain known to be accumulated in the lysosomes of neutrophils and monocytes. It is used mainly to identify and detect the activated state of these cells. We have found that the extracellular application of physiological ceramide, i.e., a product of sphingomyelin hydrolysis and a newly defined in...

journal_title：Annals of hematology

authors： Sipka S,Antal-Szalmás P,Szöllösi I,Csipö I,Lakos G,Szegedi G

更新日期：2000-02-01 00:00:00

abstract：:Immune thrombocytopenia (ITP) is characterised by a transient or persistent decrease in platelets accompanied by an increased risk of bleeding, which can have a significant negative impact on patients' health-related quality of life. The condition has long been associated with an increased rate of immune-mediated plat...

journal_title：Annals of hematology

authors： Kühne T,Imbach P

更新日期：2010-07-01 00:00:00

abstract：:Hemoglobin (Hb) Korle-Bu (beta73; Asp-Asn) is the most frequent of the rare beta-chain variants in the population of West Africa whereas Hb E (beta26; Glu-Lys) is common among the Southeast Asian population. We report a hitherto undescribed condition in which these two beta-chain variants co-segregate. The proband was...

journal_title：Annals of hematology

authors： Changtrakun Y,Fucharoen S,Ayukarn K,Siriratmanawong N,Fucharoen G,Sanchaisuriya K

更新日期：2002-07-01 00:00:00

abstract：:Interstitial pneumonia (IP) is a lethal complication in lymphoma patients undergoing chemotherapy. A total of 2212 consecutive patients diagnosed with lymphoma between 2009 and 2014 were enrolled in the present study. IP was defined as diffuse pulmonary interstitial infiltrate found on computed tomography scans. IP wa...

journal_title：Annals of hematology

authors： Liu WP,Wang XP,Zheng W,Xie Y,Tu MF,Lin NJ,Ping LY,Ying ZT,Zhang C,Deng LJ,Ding N,Wang XG,Song YQ,Zhu J

更新日期：2018-01-01 00:00:00

abstract：:Over 80% of the α-thalassemia cases in southern China are caused by large deletions involving the α-globin gene cluster on chromosome 16p13.3. Here, we characterized a novel 27.6-kb deletion on the α-globin gene cluster in a Chinese family. Its breakpoints were detected to lie between coordinates 9079 and 36718 of the...

journal_title：Annals of hematology

authors： Wei XF,Shang X,He DQ,Huang JW,Zhang XH,Xu XM

更新日期：2011-01-01 00:00:00

abstract：:Extranodal natural killer (NK)/T cell lymphoma-associated hemophagocytic syndrome (HPS) (NK/T-LAHS) is a heterogeneous and life-threatening disease, which warrants investigation of its risk factors and clinical features. We retrospectively analyzed the clinical records of 202 patients with extranodal NK/T cell lymphom...

journal_title：Annals of hematology

authors： Jia J,Song Y,Lin N,Liu W,Ping L,Zheng W,Wang X,Xie Y,Tu M,Zhang C,Ying Z,Deng L,Ding N,Zhu J

更新日期：2016-12-01 00:00:00

abstract：:Recent studies have demonstrated that direct cell-to-cell interaction is one of the microenvironment factors for transdifferentiation of adult stem cells into cardiomyocytes. We investigated whether transdifferentiation of mesenchymal stem cells (MSCs) into cardiomyocytes was dependent on developmental stages of cocul...

journal_title：Annals of hematology

authors： Yoon J,Shim WJ,Ro YM,Lim DS

更新日期：2005-10-01 00:00:00

abstract：:Repeated courses of HD IVIg are reported to induce stable remission in a significant proportion of adults with chronic refractory ITP. We have treated 14 such patients obtaining a remission rate quite comparable to the 5-10% of spontaneous remission. ...

journal_title：Annals of hematology

authors： Schiavotto C,Ruggeri M,Rodeghiero F

更新日期：1995-02-01 00:00:00

abstract：:Neutropenic enterocolitis (NE) is a severe gastrointestinal complication in patients who undergo aggressive chemotherapy. It is a necrotizing inflammation of the cecum, colon, and the terminal part of the ileum. The serious clinical state of NE patients requires very frequent surgical consultations; however, in a few ...

journal_title：Annals of hematology

authors： Wach M,Dmoszynska A,Wasik-Szczepanek E,Pozarowski A,Drop A,Szczepanek D

更新日期：2004-08-01 00:00:00

abstract：:We describe a unique case of IgG lambda myeloma in which a plasma cell leukemia developed and the paraprotein changed from IgG lambda to lambda chain, the latter inducing fatal renal failure. In addition, J-chain was detected in the cytoplasm of the plasma cell leukemia cells. ...

journal_title：Annals of hematology

authors： Sawamura M,Murayama K,Tokizawa S,Matsushima T,Tamura J,Murakami H,Naruse T,Tsuchiya J

更新日期：1993-04-01 00:00:00

abstract：:Platelet function disorders (PFD) and Von Willebrand disease (VWD) are among the uncommon causes of bleeding in haematological practice. The inherited variety of PFD includes defects in platelet adhesion, aggregation, secretion and platelet procoagulant activities. VWD is classified into three major categories-type 1 ...

journal_title：Annals of hematology

authors： Gupta PK,Charan VD,Saxena R

更新日期：2007-06-01 00:00:00

abstract：:NUT midline carcinoma (NMC) is an aggressive neoplasm and mainly involved in the head and neck area. The defining genetic hallmark on these tumors is that testis-specific nuclear gene (NUTM1) fuses to bromodomain protein family member 4 gene (BRD4), resulting in the formation of BRD4-NUTM1 transcript. Here, we report ...

journal_title：Annals of hematology

authors： Cheng Z,Luo Y,Zhang Y,Wang Y,Chen Y,Xu Y,Peng H,Zhang G

更新日期：2020-07-01 00:00:00

abstract：:The B cell surface antigen CD19 is a target for treating B cell malignancies, such as B cell precursor acute lymphoblastic leukemia and B cell non-Hodgkin lymphoma. The BiTE® immuno-oncology platform includes blinatumomab, which is approved for relapsed/refractory B cell precursor acute lymphoblastic leukemia and B ce...

journal_title：Annals of hematology

authors： Viardot A,Locatelli F,Stieglmaier J,Zaman F,Jabbour E

更新日期：2020-10-01 00:00:00

abstract：:Previous studies have suggested that adherence to imatinib therapy can be an obstacle among patients with chronic myeloid leukemia (CML). We studied adherence to imatinib therapy among CML patients treated at the Sahlgrenska University Hospital. We identified all CML patients that were alive at the 1st of January 2010...

journal_title：Annals of hematology

authors： Jönsson S,Olsson B,Söderberg J,Wadenvik H

更新日期：2012-05-01 00:00:00

abstract：:2-Chlorodeoxyadenosine (2-CdA) is a purine analogue which has proved to be active in acute myeloid leukemia (AML), especially in children. In adults, results yielded by 2-CdA alone or with ara-C were less encouraging. Here we report on the efficacy of 2-CdA with or without daunorubicin (DNR) in 19 relapsing or refract...

journal_title：Annals of hematology

authors： Van Den Neste E,Martiat P,Mineur P,Delannoy A,Doyen C,Zenebergh A,Michaux JL,Ferrant A

更新日期：1998-01-01 00:00:00

abstract：:Haemoglobinopathies are the world's most frequently found monogenic disorders. In the cases with high oxygen affinity, the decrease in the liberation of the oxygen determines a secondary erythrocytosis. In this work, we present 17 unrelated families of Caucasian race and of Spanish origin, with ten variants of haemogl...

journal_title：Annals of hematology

authors： González Fernández FA,Villegas A,Ropero P,Carreño MD,Anguita E,Polo M,Pascual A,Henández A

更新日期：2009-03-01 00:00:00

abstract：:Cytokines and adhesion molecules play an important role in the pathophysiology of vaso-occlusion in sickle cell disease (SCD), and their in vivo profiles are potential tools for assessing SCD severity. We compared steady-state soluble vascular cell adhesion molecule-1 (sVCAM-1) serum levels to clinical (painful crisis...

journal_title：Annals of hematology

authors： Schnog JB,Rojer RA,Mac Gillavry MR,Ten Cate H,Brandjes DPM,Duits AJ

更新日期：2003-02-01 00:00:00

abstract：:Sickle cell patients are characterized by stress erythropoiesis involving cytokines, growth factors, and adhesion molecules. We set out to determine whether serum soluble vascular cell adhesion molecule-1 (sVCAM-1) levels, which are inversely related to red blood cell counts in sickle cell disease (SCD), reflect eryth...

journal_title：Annals of hematology

authors： Duits AJ,Rojer RA,van Endt T,MacGillavry MR,ten Cate H,Brandjes DP,Schnog JB

更新日期：2003-03-01 00:00:00

abstract：:The aim of the present study was to investigate the prognostic role of pre- and/or early post-autologous stem cell transplantation (ASCT) (18)F-flourodeoxyglucose (FDG) positron emission tomography (PET) in patients with relapsed/refractory Hodgkin lymphoma. Forty-three consecutive patients were enrolled in this study...

journal_title：Annals of hematology

authors： Sucak GT,Özkurt ZN,Suyani E,Yaşar DG,Akdemir ÖÜ,Aki Z,Yeğin ZA,Yağci M,Kapucu ÖL

更新日期：2011-11-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a well-recognized complication in pediatric oncology patients. Studies in adult oncology patients have suggested a potential negative association between VTE and survival, but this association has not been examined in pediatric patients yet. The aim of this study was to assess the assoc...

journal_title：Annals of hematology

authors： Forbrigger Z,Kuhle S,Brown MM,Moorehead PC,Digout C,Kulkarni K

更新日期：2018-10-01 00:00:00

abstract：:The introduction of rituximab into the primary treatment of malignant lymphomas of the B cell lineage has had a major impact on the management of these diseases. In addition, prolonged exposure to rituximab as maintenance therapy has been beneficial in patients with follicular lymphoma and mantle cell lymphoma. For th...

journal_title：Annals of hematology

authors： Witzens-Harig M,Reiz M,Heiss C,Benner A,Hensel M,Neben K,Dreger P,Kraemer A,Ho AD

更新日期：2009-01-01 00:00:00

abstract：:Standard conditioning for allogeneic bone marrow transplantation induces high transplant-related mortality (TRM) in patients with a poor performance status. Less intensive regimens have been tested to reduce the TRM; our purpose was to evaluate the feasibility and tolerability of a new combination: thiotepa and fludar...

journal_title：Annals of hematology

authors： Alessandrino EP,Bernasconi P,Colombo AA,Caldera D,Bonfichi M,Pagnucco G,Malcovati L,Varettoni M,Lazzarino M,Bernasconi C

更新日期：2001-09-01 00:00:00

abstract：:Sickle cell anaemia (SCA; HbSS) is characterised by its clinical variability, which is only partly explained by known genetic factors. Environmental factors are known to contribute to acute problems but their importance in chronic complications has not been analysed. We have studied 93 children with SCA in a single in...

journal_title：Annals of hematology

authors： Mittal H,Roberts L,Fuller GW,O'Driscoll S,Dick MC,Height SE,Thein SL,Rees DC

更新日期：2009-06-01 00:00:00

abstract：:Many studies have confirmed that overexpressed WT1 exists in leukemic cells, especially in AML. However, the immunophenotypic features of this sort of leukemic cells remain to be unclarified. We retrospectively analyzed the immunophenotype of 283 newly diagnosed AML patients with intermediated and poor cytogenetic ris...

journal_title：Annals of hematology

authors： Wang XR,Chang Y,Yuan XY,Wang YZ,Qin YZ,Ruan GR,Lai YY,Liu YR

更新日期：2020-02-01 00:00:00

abstract：:This study aimed to determine whether dose-dense therapy improves 3-year survival over the standard therapy for untreated aggressive lymphoma. One hundred and fifteen patients with untreated aggressive lymphoma were stratified by center, age, and international prognostic index and randomized to one of two treatment ar...

journal_title：Annals of hematology

authors： Fridrik MA,Hausmaninger H,Lang A,Drach J,Krieger O,Geissler D,Michlmayr G,Ulsperger E,Chott A,Oberaigner W,Greil R

更新日期：2010-03-01 00:00:00

abstract：:Pulmonary infections are a major cause of morbidity and mortality in patients with hematologic malignancy. Bronchoscopy is at present still the traditional first investigation in immunosuppressed patients that have developed pulmonary infiltrates. There is limited data available on the validity of fiberoptic bronchosc...

journal_title：Annals of hematology

authors： Kim SW,Rhee CK,Kang HS,Lee HY,Kang JY,Kim SJ,Kim SC,Lee SY,Kim YK,Lee JW

更新日期：2015-01-01 00:00:00