Oral high-dose sucrosomial iron vs intravenous iron in sideropenic anemia patients intolerant/refractory to iron sulfate: a multicentric randomized study.

abstract：:Aberrant promoter methylation of RASSF6 and RASSF10 occurs at a high frequency in acute lymphoblastic leukemia (ALL). Because of the complexity of the current minimal residual disease (MRD) detecting-methods, the DNA methylation status of the RASSF6 and RASSF10 genes could potentially become biomarkers for the assessm...

journal_title：Annals of hematology

authors： Younesian S,Shahkarami S,Ghaffari P,Alizadeh S,Mehrasa R,Ghaffari SH

更新日期：2019-12-01 00:00:00

abstract：:We discuss possible justifications to split study populations from a biometrical point of view. The existence of prognostic differences between subgroups are neither a sufficient nor a necessary reason to justify a splitting decision. There are essentially two separate types of relevant arguments to justify a split of...

journal_title：Annals of hematology

authors： Hasenclever D,Loeffler M

更新日期：2001-01-01 00:00:00

abstract：:t(8;16)(p11.2;p13.3)/KAT6A-CREBBP is a rare recurrent cytogenetic abnormality associated with acute myeloid leukemia (AML). We report 15 cases with t(8;16)(p11.2;p13.3). All patients were adult and had AML: 13 women and 2 men, with a median age of 50 years. Ten patients had a history of malignancy and received cytotox...

journal_title：Annals of hematology

authors： Xie W,Hu S,Xu J,Chen Z,Medeiros LJ,Tang G

更新日期：2019-05-01 00:00:00

abstract：:A case of disseminated infection with Fusarium oxysporum following chemotherapy of acute myelogenous leukemia is reported. Antifungal treatment was successful with a 13-day course of oral terbinafine 250 mg t.i.d. in combination with amphotericin B deoxycholate 1.0-1.5 mg/kg qd and subsequently intravenous liposomal a...

journal_title：Annals of hematology

authors： Rothe A,Seibold M,Hoppe T,Seifert H,Engert A,Caspar C,Karthaus M,Fätkenheuer G,Bethe U,Tintelnot K,Cornely OA

更新日期：2004-06-01 00:00:00

abstract：:Circulating homocysteine is a risk factor of cardiovascular and cerebrovascular events. Hyperhomocysteinemia may be an early indicator for vitamin B12 disorders because cobalamin is a cofactor in the remethylation process of homocysteine. Serum holotranscobalamin (holoTC II) becomes decreased before the development of...

journal_title：Annals of hematology

authors： Serefhanoglu S,Aydogdu I,Kekilli E,Ilhan A,Kuku I

更新日期：2008-05-01 00:00:00

abstract：:Blastic transformation of essential thrombocythemia (ET) preceded by chemotherapy is occasionally described in the literature. In ET as well as in other myeloproliferative disorders the leukemogenic effect of alkylating agents and (32)P is well established, and recent reports also indicate a certain leukemogenic effec...

journal_title：Annals of hematology

authors： Andersson PO,Ridell B,Wadenvik H,Kutti J

更新日期：2000-01-01 00:00:00

abstract：:Abnormal blood coagulation often occurs in critically ill patients, which seriously affects their prognosis. This retrospective study investigated the implications of changes in blood coagulation in patients with coronavirus disease 2019 (COVID-19). Records were reviewed for patients admitted with COVID-19 between Feb...

journal_title：Annals of hematology

authors： Luo HC,You CY,Lu SW,Fu YQ

更新日期：2021-01-01 00:00:00

abstract：:Hematopoietic recovery after high-dose chemotherapy (HDC) in the treatment of hematological diseases may be slow and/or incomplete. This is generally attributed to progressive hematopoietic stem cell failure, although defective hematopoiesis may be in part due to poor stromal function. Chemotherapy is known to damage ...

journal_title：Annals of hematology

authors： Kemp K,Morse R,Wexler S,Cox C,Mallam E,Hows J,Donaldson C

更新日期：2010-07-01 00:00:00

abstract：:Nodal peripheral T cell lymphomas (nPTCL) present aggressive clinical course, and its heterogeneous nature and poor prognosis with current therapeutic strategies make it a target for the development of new prognostic markers. Thus, we investigated tumor-associated macrophages (TAM) according to the number of cells exp...

journal_title：Annals of hematology

authors： de Pádua Covas Lage LA,Hamasaki DT,Moreira FR,Rocha V,Zerbini MCN,Pereira J

更新日期：2019-09-01 00:00:00

abstract：:The aims of this study are to determine the replacement rate of damaged hepatocytes by donor-derived cells in sex-mismatched recipient patients with thalassemia major and to determine whether co-transplantation of mesenchymal stem cells and hematopoietic stem cells (HSCs) can alleviate liver fibrosis. Ten sex-mismatch...

journal_title：Annals of hematology

authors： Ghavamzadeh A,Sotoudeh M,Hashemi Taheri AP,Alimoghaddam K,Pashaiefar H,Jalili M,Shahi F,Jahani M,Yaghmaie M

更新日期：2018-02-01 00:00:00

abstract：:We found increased numbers of CD28-negative T cells in a patient with multicentric Castleman's disease (MCD), who also had significantly decreased interleukin-2 (IL-2) production and impaired T-cell proliferation. The presence of CD28-negative T cells may be indicative of a functional T-cell defect in MCD. ...

journal_title：Annals of hematology

authors： Ishiyama T,Koike M,Kakimoto T,Akimoto Y,Tsuruoka N

更新日期：1996-10-01 00:00:00

abstract：:Platelet concentrates were pretreated with a stable synthetic prostacyclin analogue (Iloprost) at two different concentrations before the second centrifugation step (pelleting step) of preparation. This resulted in loss of platelet sensitivity to aggregating agents. To mimic the situation after transfusion and to asse...

journal_title：Annals of hematology

authors： Elias M,Heethuis A,Weggemans M,Bom V,Blom N,McShine RL,Halie MR,Smit Sibinga CT

更新日期：1992-06-01 00:00:00

abstract：:Although B chronic lymphocytic leukemia (B-CLL) cells express the alpha chain of the interleukin-2 (IL-2) receptor CD25, little is known about the effect of IL-2 on apoptosis in B-CLL cells. We have shown previously that stimulation of B-CLL cells with a CpG-oligonucleotide induces IL-2 high affinity receptors. In our...

journal_title：Annals of hematology

authors： Decker T,Bogner C,Oelsner M,Peschel C,Ringshausen I

更新日期：2010-11-01 00:00:00

abstract：:We have established reference values of peripheral blood lymphocyte subsets in healthy female Wistar rats under highly standardized conditions. Using monoclonal antibodies and flow cytometry, T lymphocytes (OX19+), B lymphocytes (OX6+ and anti-Ig+), T-helper/inducer (W3/25+), and T-suppressor/cytotoxic subsets (OX8+) ...

journal_title：Annals of hematology

authors： Franch A,Castellote C,Pelegrí C,Tolosa E,Castell M

更新日期：1993-09-01 00:00:00

abstract：:We investigated whether human peripheral blood mononuclear cells (PBMC) express prothrombinase following stimulation with bacterial lipopolysaccharide (LPS). LPS-stimulated PBMC devoid of contaminating platelets failed to activate prothrombin directly. Addition of platelets did not result in expression of prothrombina...

journal_title：Annals of hematology

authors： Pejler G,Geczy CL

更新日期：2001-05-01 00:00:00

abstract：:The cytogenetic and molecular data is recognized as the most valuable prognostic factor in acute myeloid leukemia (AML). Our aim was to systemically analyze the cytogenetics of Korean AML patients and to compare the cytogenetic profiles of various races to identify possible geographic heterogeneity. We retrospectively...

journal_title：Annals of hematology

authors： Byun JM,Kim YJ,Yoon HJ,Kim SY,Kim HJ,Yoon J,Min YH,Cheong JW,Park J,Lee JH,Hong DS,Park SK,Kim HJ,Ahn JS,Shin HJ,Chung JS,Lee WS,Lee SM,Park Y,Kim BS,Lee JH,Lee KH,Jung CW,Jang JH,Min WS,Park TS,AML\/M

更新日期：2016-08-01 00:00:00

abstract：:In the context of discussions on the reproducibility of clinical studies, we reanalyzed a prospective randomized study on the role of splenic irradiation as adjunct to the conditioning for hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML). Between 1986 and 1989, a total of 229 patients ...

journal_title：Annals of hematology

authors： Gratwohl A,Iacobelli S,Bootsman N,van Biezen A,Baldomero H,Arcese W,Arnold R,Bron D,Cordonnier C,Ernst P,Ferrant A,Frassoni F,Gahrton G,Richard C,Kolb HJ,Link H,Niederwieser D,Ruutu T,Schattenberg A,Schmitz N,Torr

更新日期：2016-05-01 00:00:00

abstract：:The effects of romiplostim on bone marrow morphology were evaluated in adults with immune thrombocytopenia (ITP). Patients with platelet counts <50 × 10(9)/L, ≥1 prior ITP therapies, and no collagen at baseline received weekly subcutaneous romiplostim starting at 1 μg/kg, adjusted to maintain platelet counts between 5...

journal_title：Annals of hematology

authors： Janssens A,Rodeghiero F,Anderson D,Chong BH,Boda Z,Pabinger I,Červinek L,Terrell DR,Wang X,Franklin J

更新日期：2016-06-01 00:00:00

abstract：:Acute leukemia (AL) patients may experience more than one episode of bloodstream infection (BSI) caused by the same pathogen during the entire chemotherapy program. In order to identify factors influencing BSI recurrence (R-BSI) during subsequent phases of treatment, we analyzed all BSIs occurring to consecutively tre...

journal_title：Annals of hematology

authors： Cattaneo C,Antoniazzi F,Tumbarello M,Skert C,Borlenghi E,Schieppati F,Cerqui E,Pagani C,Petullà M,Re A,Rossi G

更新日期：2014-05-01 00:00:00

abstract：:Interferon alpha (IFN) inhibits the growth of the abnormal clone in patients with myeloproliferative disorders, leading to a reduction of the clinical and laboratory signs of the pathologic myeloproliferation. The therapeutic efficacy of IFN in polycythemia vera (PV) is demonstrated by the summarized treatment results...

journal_title：Annals of hematology

authors： Lengfelder E,Berger U,Hehlmann R

更新日期：2000-03-01 00:00:00

abstract：:The use of prophylactic antimicrobials during autologous peripheral blood stem cell transplantation (APBSCT) remains controversial. A prospective study was therefore conducted to examine whether the use of prophylactic antimicrobials is necessary. In this study, all the antimicrobials were given therapeutically rather...

journal_title：Annals of hematology

authors： Yeh SP,Chiu CF,Lo WJ,Lin CL,Hsueh CT,Liao YM,Shen YC

更新日期：2003-01-01 00:00:00

abstract：:There is little information about cardiovascular adverse event (CV-AE) incidence in chronic myeloid leukemia (CML) patients treated with bosutinib in the real-life practice. We identified 54 consecutive CML patients treated with bosutinib, stratified according to the Systematic Coronary Risk Evaluation (SCORE) assessm...

journal_title：Annals of hematology

authors： Caocci G,Mulas O,Abruzzese E,Iurlo A,Annunziata M,Orlandi EM,Galimberti S,Binotto G,Sgherza N,Luciano L,Martino B,Russo Rossi A,Bonifacio M,Fozza C,Trawinska MM,Cattaneo D,Elena C,Baratè C,De Gregorio F,Molica M,L

更新日期：2019-08-01 00:00:00

abstract：:This study outlines trends in quality of delivered non-Hodgkin's lymphoma (NHL) care in the Netherlands between 2007 and 2011 and to what extend this was influenced by the national Visible Care program, which aimed at increasing transparency by providing insight into the quality of healthcare. We analyzed data collect...

journal_title：Annals of hematology

authors： Stienen JJ,Ottevanger PB,Wennekes L,van de Schans SA,Dekker HM,van der Maazen RW,van Krieken JH,Blijlevens NM,Hermens RP,PEARL study group.

更新日期：2015-07-01 00:00:00

abstract：:An acute leukemia with an unusual immunophenotype developed in a 17-year-old girl. At the initial presentation, extramedullary involvement was not evident, but with advancing disease, massive splenomegaly and an osteolytic rib tumor developed. The disease was aggressive and refractory to intensive chemotherapeutic reg...

journal_title：Annals of hematology

authors： Ino T,Tsuzuki M,Okamoto M,Shamoto M,Hirano M

更新日期：1999-01-01 00:00:00

abstract：:Expression of long non-coding RNA KIAA0125 has been incorporated in various gene expression signatures for prognostic prediction in acute myeloid leukemia (AML) patients, yet its functions and clinical significance remain unclear. This study aimed to investigate the clinical and biological characteristics of AML beari...

journal_title：Annals of hematology

authors： Wang YH,Lin CC,Hsu CL,Hung SY,Yao CY,Lee SH,Tsai CH,Hou HA,Chou WC,Tien HF

更新日期：2021-02-01 00:00:00

abstract：:Alemtuzumab, a humanized anti-CD52 monoclonal antibody, is used in patients with refractory chronic lymphocytic leukaemia (CLL). We report results in health care with alemtuzumab on consecutive, advanced-stage patients from a well-defined geographical region. Records from 1,301 patients (Stockholm-Cancer-Registry 1991...

journal_title：Annals of hematology

authors： Eketorp Sylvan S,Lundin J,Ipek M,Palma M,Karlsson C,Hansson L

更新日期：2014-10-01 00:00:00

abstract：:Malignant lymphomas are a heterogenous group of malignancies, belonging to the 10 most frequent types of cancers worldwide. In indolent lymphoma only patients with limited stage I/II (Ann Arbor) can be potentially cured by local irradiation. However, about 85% of cases present with advanced stage; for these patients n...

journal_title：Annals of hematology

authors： Buske C,Dreyling H,Unterhalt M,Hiddemann W

更新日期：2004-01-01 00:00:00

abstract：:Multiresistant bacterial infections are a potentially life-threatening condition in acute leukaemia (AL) patients. We aimed to better define the very recent epidemiology and outcome of bloodstream infections (BSIs) in a real-life setting. We prospectively collected all consecutive febrile/infectious episodes occurring...

journal_title：Annals of hematology

authors： Cattaneo C,Zappasodi P,Mancini V,Annaloro C,Pavesi F,Skert C,Ferrario A,Todisco E,Saccà V,Verga L,Passi A,Da Vià M,Ferrari S,Mometto G,Petullà M,Nosari A,Rossi G

更新日期：2016-12-01 00:00:00

abstract：:The rarity of severe complications of this disease in children makes randomized clinical trials in immune thrombocytopenia (ITP) unfeasible. Therefore, the current management recommendations for ITP are largely dependent on clinical expertise and observations. As part of its discussions during the Intercontinental Coo...

journal_title：Annals of hematology

authors： Tamary H,Roganovic J,Chitlur M,Nugent DJ

更新日期：2010-07-01 00:00:00

abstract：:Co-inheritance of triplicated α-genes can alter the clinical and hematological phenotypes of β-thalassemias. We evaluated the phenotypic diversity and transfusion requirements in β-thalassemia heterozygotes, homozygotes, and normal individuals with associated α-gene triplication. Clinical and hematological evaluation ...

journal_title：Annals of hematology

authors： Mehta PR,Upadhye DS,Sawant PM,Gorivale MS,Nadkarni AH,Shanmukhaiah C,Ghosh K,Colah RB

更新日期：2015-12-01 00:00:00