Stabilization of standard platelet concentrates and minimization of the platelet storage lesion by a prostacyclin analogue.

abstract：:The practical usefulness of Helicobacter pylori eradication for immune thrombocytopenia (ITP) patients is still controversial. However, some ITP patients respond to H. pylori eradication. We conducted a multi-center, open label, prospective phase II study to define the efficacy and toxicities of H. pylori eradication ...

journal_title：Annals of hematology

authors： Kim H,Lee WS,Lee KH,Bae SH,Kim MK,Joo YD,Zang DY,Jo JC,Lee SM,Lee JH,Lee JH,Kim DY,Ryoo HM,Hyun MS,Kim HJ,CoOperative Study Group A for Hematology (COSAH).

更新日期：2015-05-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a rare multisystem disorder characterized by proliferation and diffuse infiltration multiple organs with histiocytes, including the central nervous system (CNS). Neurological manifestations of HLH have been recognized in different studies with children, but they remain relat...

journal_title：Annals of hematology

authors： Cai G,Wang Y,Liu X,Han Y,Wang Z

更新日期：2017-08-01 00:00:00

abstract：:A female patient presenting with B-CLL and coincident eosinophilia-myalgia syndrome (EMS) after ingestion of L-tryptophan is described. The manifestations of EMS disappeared completely during treatment with cyclophosphamide/prednisone. and there was an intermittent clinical remission of CLL with absence of the monoclo...

journal_title：Annals of hematology

authors： Böhme A,Wolter M,Hoelzer D

更新日期：1998-11-01 00:00:00

abstract：:We have performed a retrospective analysis of all patients with extragastric mucosa-associated lymphoid tissue (MALT) lymphoma treated at our institution to compare the efficacy of first-line therapeutic modalities including surgery, radiation, systemic therapy, and antibiotics. One hundred eighty-five patients with e...

journal_title：Annals of hematology

authors： Wöhrer S,Kiesewetter B,Fischbach J,Müllauer L,Troch M,Lukas J,Mayerhoefer ME,Raderer M

更新日期：2014-08-01 00:00:00

abstract：:In 1989, a prospective randomized multicenter study was initiated in order to determine the safety and efficacy of oral clodronate in myeloma patients. The primary objective of this long-term trial is to evaluate whether supportive clodronate is able to prevent or retard the progression of bone disease and reduce the ...

journal_title：Annals of hematology

authors： Clemens MR,Fessele K,Heim ME

更新日期：1993-03-01 00:00:00

abstract：:We monitored platelet activation by means of P-selectin and platelet monocyte aggregates (PMA) and platelet function by whole blood multiple electrode aggregometry and platelet adhesion under high shear in chronic immune thrombocytopenia patients to define changes in platelet activation during treatment with eltrombop...

journal_title：Annals of hematology

authors： Haselboeck J,Pabinger I,Ay C,Koder S,Panzer S

更新日期：2012-01-01 00:00:00

abstract：:In vivo, growth factors are currently investigated for their capacity to trigger leukemic stem cells into cycle and thus overcome kinetic drug resistance. In this study, the susceptibility of leukemic clonogenic cells to individual growth factors was related to cytosine-arabinoside (Ara-C) sensitivity. The effects of ...

journal_title：Annals of hematology

authors： Van der Lely N,De Witte T,Wessels J,Raymakers R,Muus P,Preijers F

更新日期：1994-05-01 00:00:00

abstract：:Repeated courses of HD IVIg are reported to induce stable remission in a significant proportion of adults with chronic refractory ITP. We have treated 14 such patients obtaining a remission rate quite comparable to the 5-10% of spontaneous remission. ...

journal_title：Annals of hematology

authors： Schiavotto C,Ruggeri M,Rodeghiero F

更新日期：1995-02-01 00:00:00

abstract：:Early cytomegalovirus (CMV) replication (eCMV) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been suggested as an independent factor that reduces leukemia relapse risk. We retrospectively analyzed 74 patients with acute myeloid leukemia (AML) who underwent allo-HSCT between August 2006 and S...

journal_title：Annals of hematology

authors： Jang JE,Kim SJ,Cheong JW,Hyun SY,Kim YD,Kim YR,Kim JS,Min YH

更新日期：2015-02-01 00:00:00

abstract：:Monoclonal immunoglobulin, as a marker for monoclonal gammopathy, is evaluated by protein electrophoresis (PEP) and immunofixation electrophoresis (IFE). However, PEP and IFE are not satisfactory in sensitivity, objectivity, and facility. Recently, a highly sensitive, automated immunoassay for measurement of free ligh...

journal_title：Annals of hematology

authors： Kang SY,Suh JT,Lee HJ,Yoon HJ,Lee WI

更新日期：2005-09-01 00:00:00

abstract：:The somatic mutations of isocitrate dehydrogenase genes (IDH1 and IDH2) have been identified in a proportion of hematologic malignancies. We examined IDH1 R132 and IDH2 R140/R172 mutations by high resolution melting analysis and direct sequencing in Chinese patients with different myeloid malignancies including 198 ac...

journal_title：Annals of hematology

authors： Lin J,Yao DM,Qian J,Chen Q,Qian W,Li Y,Yang J,Wang CZ,Chai HY,Qian Z,Xiao GF,Xu WR

更新日期：2012-04-01 00:00:00

abstract：:Iron status, i.e. serum ferritin and haemoglobin (Hb) levels, was assessed in a population survey in 1994 (Dan-Monica 10) comprising 1319 Caucasian Danish women in age cohorts of 40, 50, 60 and 70 years. In the entire series, ferritin levels increased significantly from 40 years to 60 years of age. The prevalence of s...

journal_title：Annals of hematology

authors： Milman N,Byg KE,Ovesen L

更新日期：2000-11-01 00:00:00

abstract：:Steroid-resistant acute graft-versus-host disease (GVHD) of the gastrointestinal tract associates with important morbidity and mortality. While high-dose steroids are the established first-line therapy in GVHD, no second-line therapy is generally accepted. In this analysis of 65 consecutive patients with severe, stero...

journal_title：Annals of hematology

authors： Turki AT,Bayraktar E,Basu O,Benkö T,Yi JH,Kehrmann J,Tzalavras A,Liebregts T,Beelen DW,Steckel NK

更新日期：2019-10-01 00:00:00

abstract：:Since July 2017, different generic imatinib formulations have been introduced in Italy for the treatment of patients with chronic myeloid leukemia (CML). We analyzed 168 chronic phase CML patients treated with branded imatinib for a median of 12 years (range 1-16) at a single institution who switched to a single gener...

journal_title：Annals of hematology

authors： Scalzulli E,Colafigli G,Latagliata R,Pepe S,Diverio D,Stocchi F,Di Prima A,Efficace F,Martelli M,Foà R,Breccia M

更新日期：2020-12-01 00:00:00

abstract：:Hematopoietic chimerism can be used as a tool for patient management after allogeneic hematopoietic stem cell transplantation (HSCT). An increase in the proportion of recipient cells after transplantation is strongly associated with relapse in chronic myeloid leukemia. However, in acute myeloid leukemia (AML) the sign...

journal_title：Annals of hematology

authors： Waterhouse M,Bertz H,Finke J

更新日期：2014-02-01 00:00:00

abstract：:The aim of the present study was to investigate the prognostic role of pre- and/or early post-autologous stem cell transplantation (ASCT) (18)F-flourodeoxyglucose (FDG) positron emission tomography (PET) in patients with relapsed/refractory Hodgkin lymphoma. Forty-three consecutive patients were enrolled in this study...

journal_title：Annals of hematology

authors： Sucak GT,Özkurt ZN,Suyani E,Yaşar DG,Akdemir ÖÜ,Aki Z,Yeğin ZA,Yağci M,Kapucu ÖL

更新日期：2011-11-01 00:00:00

abstract：:An analysis was conducted in four members of the same family, two of whom had a history of severe bleeding associated with type 2B von Willebrand's disease (VWD) which, although found to be due to the same mutation, nevertheless exhibited different phenotype patterns in the two subjects involved. Von Willebrand's fact...

journal_title：Annals of hematology

authors： Rendal E,Penas N,Larrabeiti B,Pérez A,Vale A,López-Fernández MF,Batlle J

更新日期：2001-06-01 00:00:00

abstract：:To explore the clinicopathological characteristics and outcomes of light chain deposition disease (LCDD) in a Chinese population, we retrospectively studied the clinicopathological data, treatment, and outcomes of 48 patients with biopsy-proven LCDD from a single center. Among the patients, there were 29 males and 19 ...

journal_title：Annals of hematology

authors： Li XM,Rui HC,Liang DD,Xu F,Liang SS,Zhu XD,Huang XH,Liu ZH,Zeng CH

更新日期：2016-05-01 00:00:00

abstract：:We evaluated the clinical features, treatment modalities, treatment responses, and prognosis of our patients with immune thrombocytopenia (ITP). Furthermore, we estimated the frequency of ITP in the Thrace region of Turkey. Two hundred sixteen patients diagnosed with ITP between 2000 and 2012 at our center were retros...

journal_title：Annals of hematology

authors： Koylu A,Pamuk GE,Uyanik MS,Demir M,Pamuk ON

更新日期：2015-03-01 00:00:00

abstract：:An acute leukemia with an unusual immunophenotype developed in a 17-year-old girl. At the initial presentation, extramedullary involvement was not evident, but with advancing disease, massive splenomegaly and an osteolytic rib tumor developed. The disease was aggressive and refractory to intensive chemotherapeutic reg...

journal_title：Annals of hematology

authors： Ino T,Tsuzuki M,Okamoto M,Shamoto M,Hirano M

更新日期：1999-01-01 00:00:00

abstract：:Infections by multidrug-resistant (MDR) bacteria are a worrisome phenomenon in hematological patients. Data on the incidence of MDR colonization and related bloodstream infections (BSIs) in haematological patients are scarce. A multicentric prospective observational study was planned in 18 haematological institutions ...

journal_title：Annals of hematology

authors： Cattaneo C,Di Blasi R,Skert C,Candoni A,Martino B,Di Renzo N,Delia M,Ballanti S,Marchesi F,Mancini V,Orciuolo E,Cesaro S,Prezioso L,Fanci R,Nadali G,Chierichini A,Facchini L,Picardi M,Malagola M,Orlando V,Trecaric

更新日期：2018-09-01 00:00:00

abstract：:Acute graft-versus-host disease (aGVHD) has become the important complication post-allogeneic hematopoietic stem cell transplantation. Abnormally activated T cells might play an important role in the pathogenesis of aGVHD. But its exact mechanism remains poorly understood. T cell immune response cDNA 7 (TIRC7) has bee...

journal_title：Annals of hematology

authors： Zhu F,Qiao J,Chen W,Pan B,Wu QY,Cao J,Sang W,Yan ZL,Zeng LY,Li ZY,Xu KL

更新日期：2015-06-01 00:00:00

abstract：:Extreme thrombocytosis (ExT) has been associated with an increased bleeding risk in myeloproliferative neoplasm (MPN) patients and is included in the high risk category in treatment guidelines. Treatment of patients with ExT has not been studied in prospective trials. To study physicians' approaches to ExT, we distrib...

journal_title：Annals of hematology

authors： Koren-Michowitz M,Lavi N,Ellis MH,Vannucchi AM,Mesa R,Harrison CN

更新日期：2017-01-01 00:00:00

abstract：:Approximately 10% of patients with polycythemia vera (PV) transform to acute leukemia (blast phase) at 10 years after initial diagnosis of PV. The bone marrow pathologic, cytogenetic, and molecular features of blast phase have not been well characterized. In this study, we reviewed 422 PV patients over a period of 11 ...

journal_title：Annals of hematology

authors： Hidalgo López JE,Carballo-Zarate A,Verstovsek S,Wang SA,Hu S,Li S,Xu J,Zuo W,Tang Z,Yin CC,Medeiros LJ,Bueso-Ramos CE,Tang G

更新日期：2018-03-01 00:00:00

abstract：:Cytomegalovirus (CMV) can cause end-organ diseases including pneumonia, gastroenteritis, retinitis, and encephalitis in hematopoietic stem cell transplantation recipients. Potential differences among different CMV diseases remain uncertain. This study aimed to compare the clinical characteristics, risk factors, and mo...

journal_title：Annals of hematology

authors： Meng XY,Fu HX,Zhu XL,Wang JZ,Liu X,Yan CH,Zhang YY,Mo XD,Wang Y,Han W,Chen YH,Chen DB,Liu HX,Chang YJ,Xu LP,Liu KY,Huang XJ,Zhang XH

更新日期：2020-11-01 00:00:00

abstract：:A 77-year-old man developed pneumonitis while on chlorambucil therapy for chronic lymphocytic leukemia, with a cumulative dose of 2700 mg. The condition improved promptly with the discontinuation of the drug and initiation of steroids. A case report and review of the literature are presented in this paper. ...

journal_title：Annals of hematology

authors： Khong HT,McCarthy J

更新日期：1998-07-01 00:00:00

abstract：:Idarubicin belongs to a group of anthracyclines in which the methoxyl group in position 4 of the D ring in the aglycone moiety is replaced by a hydrogen atom. Lipophilicity is increased compared with other anthracyclines; as a result, idarubicin is the first anthracycline that can be administered orally while at the s...

journal_title：Annals of hematology

authors： Goebel M

更新日期：1993-01-01 00:00:00

abstract：:Chronic hepatitis C (CHC) and iron overload are the main causes of liver disease in β-thalassemia major (βTM). There is limited data regarding the course of CHC in this population. All patients (n=144) from the thalassemia centre of the University Hospital of Patras were evaluated (January 1981 to June 2012). Patients...

journal_title：Annals of hematology

authors： Triantos C,Kourakli A,Kalafateli M,Giannakopoulou D,Koukias N,Thomopoulos K,Lampropoulou P,Bartzavali C,Fragopanagou H,Kagadis GC,Christofidou M,Tsamandas A,Nikolopoulou V,Karakantza M,Labropoulou-Karatza C

更新日期：2013-06-01 00:00:00

abstract：:Along with their immunogenic role, dendritic cells (DCs) are also critical in maintaining tolerance to self-antigens by inducing regulatory T cells (Tregs) via the expression of the immunomodulatory enzyme indoleamine 2,3-dioxygenase 1 (IDO1). In turn, Tregs modulate the maturation and/or function of DCs. In immune th...

journal_title：Annals of hematology

authors： Catani L,Sollazzo D,Trabanelli S,Curti A,Evangelisti C,Polverelli N,Palandri F,Baccarani M,Vianelli N,Lemoli RM

更新日期：2013-01-01 00:00:00

abstract：:Thirty-four patients with acute myeloid leukemia (AML) in complete remission (CR), 30 of them aged over 60, received maintenance therapy scheduling four courses of low-dose cytarabine (LDA) 20 mg/m2/day in two subcutaneous injections for 3 weeks every 6 weeks. Each course was stopped when hematologic toxicity occurred...

journal_title：Annals of hematology

authors： Archimbaud E,Anglaret B,Thomas X,Jaubert J,Sebban C,Guyotat D,Fiere D

更新日期：1992-08-01 00:00:00