Cytogenetic profiles of 2806 patients with acute myeloid leukemia-a retrospective multicenter nationwide study.

abstract：:We analyzed the prognostic factors for a successful mobilization and peripheral blood stem cell collection in a series of 57 consecutive patients with multiple myeloma (MM); a new scoring system to predict an adequate mobilization in this subset of patients was also constructed. A total of 221 aphereses were performed...

journal_title：Annals of hematology

authors： Perea G,Sureda A,Martino R,Altés A,Martínez C,Cabezudo E,Amill B,Martín-Henao GA,González Y,Muñoz L,Peyret M,Brunet S,Sierra J

更新日期：2001-10-01 00:00:00

abstract：:Immune thrombocytopenia (ITP) is characterised by a transient or persistent decrease in platelets accompanied by an increased risk of bleeding, which can have a significant negative impact on patients' health-related quality of life. The condition has long been associated with an increased rate of immune-mediated plat...

journal_title：Annals of hematology

authors： Kühne T,Imbach P

更新日期：2010-07-01 00:00:00

abstract：:To evaluate the outcomes of refractory/relapsed cHL patients after high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) in Beijing Cancer hospital and to identify the prognostic risk factors. We retrospectively analyzed 115 relapsed/refractory cHL patients who accepted HDCT and ASCT in our can...

journal_title：Annals of hematology

authors： Xie Y,Wang X,Leng X,Zheng W,Ping L,Zhang C,Liu W,Deng L,Wu M,Song Y,Zhu J

更新日期：2020-03-01 00:00:00

abstract：:An acute leukemia with an unusual immunophenotype developed in a 17-year-old girl. At the initial presentation, extramedullary involvement was not evident, but with advancing disease, massive splenomegaly and an osteolytic rib tumor developed. The disease was aggressive and refractory to intensive chemotherapeutic reg...

journal_title：Annals of hematology

authors： Ino T,Tsuzuki M,Okamoto M,Shamoto M,Hirano M

更新日期：1999-01-01 00:00:00

abstract：:The aim of the study was to investigate the association of leptin with hematological parameters in beta-thalassemia patients in Greece. We measured plasma levels of soluble transferrin receptor (sTfR) and leptin by enzyme-linked immunosorbent assay (ELISA) in 40 beta-thalassemia patients (21 transfusion dependent and ...

journal_title：Annals of hematology

authors： Dedoussis GV,Kyrtsonis MC,Andrikopoulos NE,Voskaridou E,Loutradis A

更新日期：2002-09-01 00:00:00

abstract：:This retrospective single-center study compared thromboembolic and hemorrhagic complications, survival and causes of death in a cohort of 102 consecutive patients with myeloproliferative disorders (MPD). We included 17 patients with essential thrombocythemia (ET), 59 with polycythemia vera (PV), and 26 with osteomyelo...

journal_title：Annals of hematology

authors： Brodmann S,Passweg JR,Gratwohl A,Tichelli A,Skoda RC

更新日期：2000-06-01 00:00:00

abstract：:Extramedullary (e) relapse in multiple myeloma(MM) has an adverse prognosis, but knowledge concerning biological features and preferred treatment is scarce. We screened the myeloma registry of our institution for eMM relapses and identified 24 cases among 357 patients (pts).Only 8% of eMM relapses occurred after initi...

journal_title：Annals of hematology

authors： Rasche L,Bernard C,Topp MS,Kapp M,Duell J,Wesemeier C,Haralambieva E,Maeder U,Einsele H,Knop S

更新日期：2012-07-01 00:00:00

abstract：:In vitro studies suggest that haploinsufficiency is involved in the pathogenesis of myelodysplastic syndromes (MDS). In patients with del5q cytogenetic abnormality, RPS-14 and microRNAs (miRNAs) play a major role. In a multicenter phase II single-arm trial with lenalidomide in anemic primary del5q MDS patients with lo...

journal_title：Annals of hematology

authors： Oliva EN,Cuzzola M,Aloe Spiriti MA,Poloni A,Laganà C,Rigolino C,Morabito F,Galimberti S,Ghio R,Cortelezzi A,Palumbo GA,Sanpaolo G,Finelli C,Ricco A,Volpe A,Rodà F,Breccia M,Alimena G,Nobile F,Latagliata R

更新日期：2013-01-01 00:00:00

abstract：:Ruxolitinib is a promising option for treating steroid-refractory acute graft-versus-host disease (SR-aGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). In this study, we describe ruxolitinib treatment for SR-aGVHD in HSCT patients with Epstein-Barr virus-associated hemophagocytic lymphohisti...

journal_title：Annals of hematology

authors： Meng G,Wang J,Wang X,Wang Y,Wang Z

更新日期：2020-02-01 00:00:00

abstract：:The objective of this study was to evaluate the efficacy and safety of rituximab in the treatment of patients with idiopathic thrombocytopenic purpura (ITP). A prospective study was performed at Mubarak Al-Kabeer University Hospital involving the use of rituximab in 14 patients who had previously been treated with ste...

journal_title：Annals of hematology

authors： Alasfoor K,Alrasheed M,Alsayegh F,Mousa SA

更新日期：2009-03-01 00:00:00

abstract：:Pulmonary infections are a major cause of morbidity and mortality in patients with hematologic malignancy. Bronchoscopy is at present still the traditional first investigation in immunosuppressed patients that have developed pulmonary infiltrates. There is limited data available on the validity of fiberoptic bronchosc...

journal_title：Annals of hematology

authors： Kim SW,Rhee CK,Kang HS,Lee HY,Kang JY,Kim SJ,Kim SC,Lee SY,Kim YK,Lee JW

更新日期：2015-01-01 00:00:00

abstract：:Patients with primary refractory or relapsed acute myeloid leukemia (AML) who undergo intensive salvage chemotherapy carry a high risk of treatment failure due to infectious complications and early relapses. The study presented here assessed the effect of granulocyte colony-stimulating factor (G-CSF) on the duration o...

journal_title：Annals of hematology

authors： Kern W,Aul C,Maschmeyer G,Kuse R,Kerkhoff A,Grote-Metke A,Eimermacher H,Kubica U,Wörmann B,Büchner T,Hiddemann W

更新日期：1998-09-01 00:00:00

abstract：:Although lenalidomide plus dexamethasone (RD) is a therapeutic option for relapsed/refractory multiple myeloma (RRMM), limited real-world clinical data exist. The purpose of this study was to estimate efficacy and safety of RD in RRMM patients of the clinical practice. Data from patients at 25 university hospitals in ...

journal_title：Annals of hematology

authors： Jo JC,Lee HS,Kim K,Lee JJ,Yoon SS,Bang SM,Kim JS,Eom HS,Yoon DH,Lee Y,Shin HJ,Park Y,Lee WS,Do YR,Mun YC,Lee MH,Kim HJ,Kim SH,Kim MK,Lim SN,Cho SH,Park SK,Yi JH,Lee JH,Kim J,Min CK,Korean Multiple Myel

更新日期：2020-02-01 00:00:00

abstract：:Delayed platelet engraftment (DPE) is a common complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT). This phenomenon is also a predictor of increased treatment-related mortality and poor survival. Therefore, therapies that promote platelet engraftment to prevent DPE are needed. This pr...

journal_title：Annals of hematology

authors： Han TT,Xu LP,Liu DH,Liu KY,Wang FR,Wang Y,Yan CH,Chen YH,Sun YQ,Ji Y,Wang JZ,Zhang XH,Huang XJ

更新日期：2015-01-01 00:00:00

abstract：:Iron deficiency anemia is among the most frequent causes of disability. Intravenous iron is the quickest way to correct iron deficiency, bypassing the bottleneck of iron intestinal absorption, the only true mechanism of iron balance regulation in human body. Intravenous iron administration is suggested in patients who...

journal_title：Annals of hematology

authors： Giordano G,Napolitano M,Di Battista V,Lucchesi A

更新日期：2020-12-02 00:00:00

abstract：:HbE/Beta thalassemia (HbE/β-thalassemia) is one of the common genetic disorders in South East Asia. It is heterogeneous in its clinical presentation and molecular defects. There are genetic modifiers which have been reported to influence the disease severity of this disorder. The aim of this study was to determine the...

journal_title：Annals of hematology

authors： Azman NF,Abdullah WZ,Hanafi S,Diana R,Bahar R,Johan MF,Zilfalil BA,Hassan R

更新日期：2020-04-01 00:00:00

abstract：:Establishing reference ranges by multiparametric immunophenotyping of mature B cells in bone marrow of healthy adults is of interest because the detection of bone marrow infiltration and persistence of light chain restriction, as well as discrimination between reactive and malignant lymphocytes are important applicati...

journal_title：Annals of hematology

authors： Höffkes HG,Schmidtke G,Schmücker U,Uppenkamp M,Brittinger G

更新日期：1995-09-01 00:00:00

abstract：:Hemoglobin (Hb) Korle-Bu (beta73; Asp-Asn) is the most frequent of the rare beta-chain variants in the population of West Africa whereas Hb E (beta26; Glu-Lys) is common among the Southeast Asian population. We report a hitherto undescribed condition in which these two beta-chain variants co-segregate. The proband was...

journal_title：Annals of hematology

authors： Changtrakun Y,Fucharoen S,Ayukarn K,Siriratmanawong N,Fucharoen G,Sanchaisuriya K

更新日期：2002-07-01 00:00:00

abstract：:Expression of long non-coding RNA KIAA0125 has been incorporated in various gene expression signatures for prognostic prediction in acute myeloid leukemia (AML) patients, yet its functions and clinical significance remain unclear. This study aimed to investigate the clinical and biological characteristics of AML beari...

journal_title：Annals of hematology

authors： Wang YH,Lin CC,Hsu CL,Hung SY,Yao CY,Lee SH,Tsai CH,Hou HA,Chou WC,Tien HF

更新日期：2021-02-01 00:00:00

abstract：:Multicentric Castleman's disease (MCD) is a rare systemic lymphoproliferative disorder with too few patient series reported in the literature to have a clear idea about the etiology, outcome and the best treatment available. Systemic reactive amyloidosis is a very rare complication of MCD and its presence worsens the ...

journal_title：Annals of hematology

authors： Gholam D,Vantelon JM,Al-Jijakli A,Bourhis JH

更新日期：2003-12-01 00:00:00

abstract：:Several guidelines and recommendations on the management of chronic myeloid leukemia (CML) have been prepared by several scientific societies. The European LeukemiaNet (ELN) appointed a panel of experts who submitted their recommendations to peer-reviewed scientific journals in 2006, 2009, and 2013. Here, we make a cr...

journal_title：Annals of hematology

authors： Baccarani M,Castagnetti F,Gugliotta G,Rosti G

更新日期：2015-04-01 00:00:00

abstract：:Due to their homing properties, extranodal marginal zone B-cell lymphoma (MZBL) of mucosa-associated lymphoid tissue (MALT) type remain localized for long periods of time, and therefore have an excellent prognosis. However, if generalization and/or transformation into a diffuse large-cell lymphoma occurs, the prognosi...

journal_title：Annals of hematology

authors： Neumeister P,Hoefler G,Beham-Schmid C,Sill H,Linkesch W

更新日期：2000-12-01 00:00:00

abstract：:Thrombotic thrombocytopenia purpura (TTP) and atypical hemolytic uremic syndromes (aHUS) are distinct clinical disorders characterized by hemolytic anemia, thrombocytopenia, microthrombi, and end organ damage. TTP is characterized by a low ADAMTS13 activity level at diagnosis of <10 % ADAMTS13 activity, while aHUS is ...

journal_title：Annals of hematology

authors： Saultz JN,Wu HM,Cataland S

更新日期：2015-09-01 00:00:00

abstract：:Platelet function disorders (PFD) and Von Willebrand disease (VWD) are among the uncommon causes of bleeding in haematological practice. The inherited variety of PFD includes defects in platelet adhesion, aggregation, secretion and platelet procoagulant activities. VWD is classified into three major categories-type 1 ...

journal_title：Annals of hematology

authors： Gupta PK,Charan VD,Saxena R

更新日期：2007-06-01 00:00:00

abstract：:This paper describes six Indian families in which silent-gene beta-thalassemia was encountered by us in the past 2 years. This stresses the importance of globin-chain synthesis in the diagnosis of beta-thalassemia. Of these six cases, five were diagnosed retrospectively when they had a homozygous beta-thalassemia offs...

journal_title：Annals of hematology

authors： Nadkarni A,Pawar A,Mudera VC,Mohanty D,Colah R

更新日期：1995-01-01 00:00:00

abstract：:Aberrant promoter methylation of RASSF6 and RASSF10 occurs at a high frequency in acute lymphoblastic leukemia (ALL). Because of the complexity of the current minimal residual disease (MRD) detecting-methods, the DNA methylation status of the RASSF6 and RASSF10 genes could potentially become biomarkers for the assessm...

journal_title：Annals of hematology

authors： Younesian S,Shahkarami S,Ghaffari P,Alizadeh S,Mehrasa R,Ghaffari SH

更新日期：2019-12-01 00:00:00

abstract：:In vivo, growth factors are currently investigated for their capacity to trigger leukemic stem cells into cycle and thus overcome kinetic drug resistance. In this study, the susceptibility of leukemic clonogenic cells to individual growth factors was related to cytosine-arabinoside (Ara-C) sensitivity. The effects of ...

journal_title：Annals of hematology

authors： Van der Lely N,De Witte T,Wessels J,Raymakers R,Muus P,Preijers F

更新日期：1994-05-01 00:00:00

abstract：:NUT midline carcinoma (NMC) is an aggressive neoplasm and mainly involved in the head and neck area. The defining genetic hallmark on these tumors is that testis-specific nuclear gene (NUTM1) fuses to bromodomain protein family member 4 gene (BRD4), resulting in the formation of BRD4-NUTM1 transcript. Here, we report ...

journal_title：Annals of hematology

authors： Cheng Z,Luo Y,Zhang Y,Wang Y,Chen Y,Xu Y,Peng H,Zhang G

更新日期：2020-07-01 00:00:00

abstract：:Early cytomegalovirus (CMV) replication (eCMV) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been suggested as an independent factor that reduces leukemia relapse risk. We retrospectively analyzed 74 patients with acute myeloid leukemia (AML) who underwent allo-HSCT between August 2006 and S...

journal_title：Annals of hematology

authors： Jang JE,Kim SJ,Cheong JW,Hyun SY,Kim YD,Kim YR,Kim JS,Min YH

更新日期：2015-02-01 00:00:00

abstract：:Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in European adults. We aimed to evaluate time trends in CLL incidence and medical resource utilisation of CLL patients in the UK. We conducted a retrospective, observational cohort analysis using the UK Clinical Practice Research Datalink (CPRD) comprisi...

journal_title：Annals of hematology

authors： Pfeil AM,Imfeld P,Pettengell R,Jick SS,Szucs TD,Meier CR,Schwenkglenks M

更新日期：2015-03-01 00:00:00