Clinical features and survival of extranodal natural killer/T cell lymphoma with and without hemophagocytic syndrome.

abstract：:The efficacy of a single dose of MCNU 150 mg was evaluated in nine symptomatic patients with essential thrombocythemia (ET). As the platelet counts increased during the following 4 weeks, an extra dose of 100 mg of MCNU was administered to three patients. All patients had thrombotic or hemorrhagic complications. Seven...

journal_title：Annals of hematology

authors： Murakami H,Tamura J,Sawamura M

更新日期：1993-05-01 00:00:00

abstract：:An investigation into the effects of irradiation and of the storage time on aging and quality are a relevant issue to ensure the safety and the efficiency of irradiation in the prevention of transfusion-associated graft-versus-host disease (TA-GVHD). In this work, the biochemical properties and alterations presented b...

journal_title：Annals of hematology

authors： Maia GA,Renó Cde O,Medina JM,Silveira AB,Mignaco JA,Atella GC,Cortes VF,Barbosa LA,Santos Hde L

更新日期：2014-05-01 00:00:00

abstract：:A prospective randomized phase III study was performed to evaluate whether intensified cytarabine would induce a higher response rate and longer event-free interval as compared to low-dose cytarabine in chronic myeloid leukemia (CML). One hundred and eighteen patients with CML in early chronic phase entered the study....

journal_title：Annals of hematology

authors： Deenik W,van der Holt B,Verhoef GE,Schattenberg AV,Verdonck LF,Daenen SM,Zachée P,Westveer PH,Smit WM,Wittebol S,Schouten HC,Löwenberg B,Ossenkoppele GJ,Cornelissen JJ

更新日期：2007-02-01 00:00:00

abstract：:High-dose chemotherapy with autologous peripheral blood stem cell transplantation (PBSCT) includes the risk of infectious complications due to neutropenia and therapy-induced immune deviation. In order to understand early immune recovery in this situation, we analyzed the distribution of cell subsets by flow cytometry...

journal_title：Annals of hematology

authors： Krause SW,Rothe G,Gnad M,Reichle A,Andreesen R

更新日期：2003-10-01 00:00:00

abstract：:Anthracyclines are a major component in the therapy of non-Hodgkin's lymphoma. However, due to their cardiac toxicity potential, curative and palliative treatment is often limited in patients with preexisting cardiac dysfunction. Liposomal doxorubicin formulations have been described to be less cardiotoxic than conven...

journal_title：Annals of hematology

authors： Schmitt CJ,Dietrich S,Ho AD,Witzens-Harig M

更新日期：2012-03-01 00:00:00

abstract：:Acquired aplastic anemia (AA) and paroxysmal nocturnal hemoglobinuria (PNH) are interrelated ultra-rare diseases. Quality of life (QoL) evaluation tools used in studies for AA and PNH are unspecific and designed for cancer patients (e.g., the European Organization for Research and Treatment of Cancer Quality of Life Q...

journal_title：Annals of hematology

authors： Groth M,Singer S,Niedeggen C,Petermann-Meyer A,Röth A,Schrezenmeier H,Höchsmann B,Brümmendorf TH,Panse J

更新日期：2017-02-01 00:00:00

abstract：:Eight patients who were carriers of beta-thalassemia induced by the cd121 (G-->T) mutation are described in four nonrelated Dutch families. This mutant, which is considered rare and inherited in a dominant manner, is expressed in a different way among each of the four families and even among carriers of the same famil...

journal_title：Annals of hematology

authors： Giordano PC,Harteveld CL,Michiels JJ,Terpstra W,Schelfhout LJ,Appel IM,Batelaan D,van Delft P,Plug RJ,Bernini LF

更新日期：1998-12-01 00:00:00

abstract：:The severity of thalassemia is currently classified based on clinical manifestations and multiple tests. In the present study, we performed a plasma proteome analysis to identify differentially expressed proteins compared between normal subjects and patients with mild and severe forms of β-thalassemia/hemoglobin E (Hb...

journal_title：Annals of hematology

authors： Hatairaktham S,Srisawat C,Siritanaratkul N,Chiangjong W,Fucharoen S,Thongboonkerd V,Kalpravidh RW

更新日期：2013-03-01 00:00:00

abstract：:Recommendations for dyslipidemia management aimed at reducing arterial occlusive events (AOEs) have been recently published. So far, no data have been reported on the management of dyslipidemia in chronic myeloid leukemia (CML) patients treated with nilotinib. We investigated 369 CML adult patients, stratified accordi...

journal_title：Annals of hematology

authors： Caocci G,Mulas O,Capodanno I,Bonifacio M,Annunziata M,Galimberti S,Luciano L,Tiribelli M,Martino B,Castagnetti F,Binotto G,Pregno P,Stagno F,Abruzzese E,Bocchia M,Gozzini A,Albano F,Fozza C,Luzi D,Efficace F,Simul

更新日期：2021-01-03 00:00:00

abstract：:In a large proportion of patients with mild bleeding disorders (MBDs) no diagnosis can be established by routine coagulation tests. We investigated whether alterations in plasma clot properties account for MBDs of unknown cause. Ninety-five patients with MBDs of unknown origin and 98 age- and sex-matched healthy contr...

journal_title：Annals of hematology

authors： Gebhart J,Laczkovics C,Posch F,Ay C,Reitter-Pfoertner SE,Haslacher H,Muszbek L,Wolberg AS,Pabinger I

更新日期：2015-08-01 00:00:00

abstract：:We have performed a retrospective analysis of all patients with extragastric mucosa-associated lymphoid tissue (MALT) lymphoma treated at our institution to compare the efficacy of first-line therapeutic modalities including surgery, radiation, systemic therapy, and antibiotics. One hundred eighty-five patients with e...

journal_title：Annals of hematology

authors： Wöhrer S,Kiesewetter B,Fischbach J,Müllauer L,Troch M,Lukas J,Mayerhoefer ME,Raderer M

更新日期：2014-08-01 00:00:00

abstract：:Multiple myeloma is a malignant B-cell neoplasm that involves the skeleton in approximately 80% of the patients. With an average age of 60 years and a 5-years survival of nearly 45% Brenner et al. (Blood 111:2516-2520,35) the onset is to be classified as occurring still early in life while the disease can be very aggr...

journal_title：Annals of hematology

authors： Lütje S,de Rooy JW,Croockewit S,Koedam E,Oyen WJ,Raymakers RA

更新日期：2009-12-01 00:00:00

abstract：:We have established reference values of peripheral blood lymphocyte subsets in healthy female Wistar rats under highly standardized conditions. Using monoclonal antibodies and flow cytometry, T lymphocytes (OX19+), B lymphocytes (OX6+ and anti-Ig+), T-helper/inducer (W3/25+), and T-suppressor/cytotoxic subsets (OX8+) ...

journal_title：Annals of hematology

authors： Franch A,Castellote C,Pelegrí C,Tolosa E,Castell M

更新日期：1993-09-01 00:00:00

abstract：:We report the case of a 23-year-old female with severe neurologic dysfunction without a clear cause at the time of initial presentation. The search for an underlying malignancy revealed a slightly enlarged cervical lymph node with Hodgkin's disease (HD). There was no evidence of a brain tumor despite nonspecific brigh...

journal_title：Annals of hematology

authors： Kalinka E,Robak T,Wrzesien-Kus A,Krykowski E,Warzocha K

更新日期：2002-05-01 00:00:00

abstract：:Amifostine increases in vitro burst-forming unit-erythroid and colony-forming unit-granulocyte/granulcoyte-macrophage cultured from bone-marrow cells from patients with myelodysplastic syndrome (MDS). Several small clinical studies give divergent informations about the potential of amifostine as single agent to improv...

journal_title：Annals of hematology

authors： Hofmann WK,Seipelt G,Ottmann OG,Kalina U,Koschmieder S,Brücher J,Frickhofen N,Klausmann M,Mitrou PS,Hoelzer D

更新日期：2000-05-01 00:00:00

abstract：:There is little information about cardiovascular adverse event (CV-AE) incidence in chronic myeloid leukemia (CML) patients treated with bosutinib in the real-life practice. We identified 54 consecutive CML patients treated with bosutinib, stratified according to the Systematic Coronary Risk Evaluation (SCORE) assessm...

journal_title：Annals of hematology

authors： Caocci G,Mulas O,Abruzzese E,Iurlo A,Annunziata M,Orlandi EM,Galimberti S,Binotto G,Sgherza N,Luciano L,Martino B,Russo Rossi A,Bonifacio M,Fozza C,Trawinska MM,Cattaneo D,Elena C,Baratè C,De Gregorio F,Molica M,L

更新日期：2019-08-01 00:00:00

abstract：:While inherited X-linked (XL) isolated thrombocytopenia is a mild condition, the Wiskott-Aldrich syndrome (WAS) associates severe thrombocytopenia with an immunodeficiency component and has a poor prognosis. Whether these conditions correspond to separate genetic entities or to different mutations of the same gene(s) ...

journal_title：Annals of hematology

authors： De Saint-Basile G,Schlegel N,Caniglia M,Le Deist F,Kaplan C,Lecompte T,Piller F,Fischer A,Griscelli C

更新日期：1991-08-01 00:00:00

abstract：:The role of 18FDG-PET/CT during follow-up of patients affected by Hodgkin's lymphoma (HL) in complete remission after treatment is not fully elucidated, since a wide use of 18F fluorodeoxyglucose positron emission tomography/computed tomography (18FDG-PET/CT) in this setting could be limited by a relative high rate of...

journal_title：Annals of hematology

authors： Crocchiolo R,Fallanca F,Giovacchini G,Ferreri AJ,Assanelli A,Verona C,Pescarollo A,Bregni M,Ponzoni M,Gianolli L,Fazio F,Ciceri F

更新日期：2009-12-01 00:00:00

abstract：:Polycythemias or erythrocytoses in childhood and adolescence are very rare. Systematic data on the clinical presentation and laboratory evaluations as well as on treatment regimens are sparse. The diagnostic program in absolute erythrocytosis includes extensive clinical, hematological, biochemical, and molecular biolo...

journal_title：Annals of hematology

authors： Cario H

更新日期：2005-03-01 00:00:00

abstract：:Organizing pneumonia (OP) is a poorly understood complication of hematopoietic stem cell transplant (HSCT). We identified 15 patients diagnosed with OP following HSCT and described their clinical course. CT chest findings were remarkable for multifocal infiltrates that were predominantly consolidating or ground glass ...

journal_title：Annals of hematology

authors： Brownback KR,Frey JW,Abhyankar S

更新日期：2019-09-01 00:00:00

abstract：:We tested two Fc gamma receptor I (Fc gamma RI); six Fc gamma RII; and six Fc gamma RIII-specific monoclonal antibodies (mAb) for their capacity to inhibit monocyte and polymorphonuclear granulocyte (PMN) immune phagocytosis which is mediated by Fc gamma R. We used human red blood cells (rbc) coated with hIgG1 or mIgG...

journal_title：Annals of hematology

authors： Flesch BK,Achtert G,Neppert J

更新日期：1997-01-01 00:00:00

abstract：:Although the outcome of patients with acute myeloid leukemia (AML) has improved by optimized chemotherapy regimens and bone marrow transplantation, leukemia relapse remains one of the most challenging problems during therapy. Sustained existence of AML blasts is a fundamental determinant for the development of leukemi...

journal_title：Annals of hematology

authors： Liu J,Qin YZ,Yang S,Wang Y,Chang YJ,Zhao T,Jiang Q,Huang XJ

更新日期：2017-04-01 00:00:00

abstract：:Pulmonary infections are a major cause of morbidity and mortality in patients with hematologic malignancy. Bronchoscopy is at present still the traditional first investigation in immunosuppressed patients that have developed pulmonary infiltrates. There is limited data available on the validity of fiberoptic bronchosc...

journal_title：Annals of hematology

authors： Kim SW,Rhee CK,Kang HS,Lee HY,Kang JY,Kim SJ,Kim SC,Lee SY,Kim YK,Lee JW

更新日期：2015-01-01 00:00:00

abstract：:Infections by multidrug-resistant (MDR) bacteria are a worrisome phenomenon in hematological patients. Data on the incidence of MDR colonization and related bloodstream infections (BSIs) in haematological patients are scarce. A multicentric prospective observational study was planned in 18 haematological institutions ...

journal_title：Annals of hematology

authors： Cattaneo C,Di Blasi R,Skert C,Candoni A,Martino B,Di Renzo N,Delia M,Ballanti S,Marchesi F,Mancini V,Orciuolo E,Cesaro S,Prezioso L,Fanci R,Nadali G,Chierichini A,Facchini L,Picardi M,Malagola M,Orlando V,Trecaric

更新日期：2018-09-01 00:00:00

abstract：:2-Chlorodeoxyadenosine (2-CdA) is a purine analogue which has proved to be active in acute myeloid leukemia (AML), especially in children. In adults, results yielded by 2-CdA alone or with ara-C were less encouraging. Here we report on the efficacy of 2-CdA with or without daunorubicin (DNR) in 19 relapsing or refract...

journal_title：Annals of hematology

authors： Van Den Neste E,Martiat P,Mineur P,Delannoy A,Doyen C,Zenebergh A,Michaux JL,Ferrant A

更新日期：1998-01-01 00:00:00

abstract：:We encountered two patients who presented with hypochromic-microcytic anemia and were refractory to iron therapy. The symptoms were suggestive of anemia of chronic disease (ACD); however, there was no evidence of any such disease, either inflammatory or malignant. These patients were reminiscent of patients originally...

journal_title：Annals of hematology

authors： Besa EC,Kim PW,Haurani FI

更新日期：2000-08-01 00:00:00

abstract：:Establishing reference ranges by multiparametric immunophenotyping of mature B cells in bone marrow of healthy adults is of interest because the detection of bone marrow infiltration and persistence of light chain restriction, as well as discrimination between reactive and malignant lymphocytes are important applicati...

journal_title：Annals of hematology

authors： Höffkes HG,Schmidtke G,Schmücker U,Uppenkamp M,Brittinger G

更新日期：1995-09-01 00:00:00

abstract：:B cell-activating factor (BAFF) is a cytokine that plays a major role in the maintenance of normal B-cell development and homeostasis. It has been suggested that in multiple myeloma (MM) it might have regulatory effects on the proliferation and viability of malignant plasma cells. The aim of this study was to evaluate...

journal_title：Annals of hematology

authors： Fragioudaki M,Boula A,Tsirakis G,Psarakis F,Spanoudakis M,Papadakis IS,Pappa CA,Alexandrakis MG

更新日期：2012-09-01 00:00:00

abstract：:This study aimed to determine the clinical characteristics and prognostic significance of the meningioma 1 (MN1) gene and MN1-associated microRNA expression in Chinese adult de novo acute myeloid leukemia (AML) patients. The expression level of MN1, microRNA-20 (miR-20a), and microRNA-181b (miR-181b) in bone marrow mo...

journal_title：Annals of hematology

authors： Xiang L,Li M,Liu Y,Cen J,Chen Z,Zhen X,Xie X,Cao X,Gu W

更新日期：2013-08-01 00:00:00

abstract：:Haemoglobinopathies are the world's most frequently found monogenic disorders. In the cases with high oxygen affinity, the decrease in the liberation of the oxygen determines a secondary erythrocytosis. In this work, we present 17 unrelated families of Caucasian race and of Spanish origin, with ten variants of haemogl...

journal_title：Annals of hematology

authors： González Fernández FA,Villegas A,Ropero P,Carreño MD,Anguita E,Polo M,Pascual A,Henández A

更新日期：2009-03-01 00:00:00