Abstract：
:The effects of free fatty acids in the blood on osmotic fragility and water content of erythrocytes when combined with hyperthermia were investigated. The isotonic buffer, containing the fatty acid, was added to the erythrocyte suspension to a final concentration of 200 microM/L. The samples were kept for one hour in an incubator at 37 degrees C or 42 degrees C. The osmotic fragility of erythrocytes was determined by coil planet centrifuge system and intracellular water content was measured by gas-liquid chromatography. A high concentration of unsaturated fatty acid and hyperthermia caused the increase in intracellular water and the decrease in osmotic resistance of the red blood cells compared to saturated fatty acid and the control. The present experiment demonstrated that unsaturated fatty acid was one of the principal chemical and metabolic factors which caused sports anemia.
journal_name
Life Scijournal_title
Life sciencesauthors
Kogawa H,Yabushita N,Nakajima T,Kageyama Kdoi
10.1016/s0024-3205(97)01184-3subject
Has Abstractpub_date
1998-01-01 00:00:00pages
823-8issue
9eissn
0024-3205issn
1879-0631pii
S0024320597011843journal_volume
62pub_type
杂志文章相关文献
LIFE SCIENCES文献大全abstract：:Autophagy is a metabolic process that maintains the homeostasis of the intracellular environment by degrading damaged proteins and organelles in lysosomes. Recently, independent studies have indicated that some hepatitis viruses develop abilities to hijack autophagy for their replication, such as hepatitis B (HBV) and...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/j.lfs.2019.117206
更新日期：2020-02-01 00:00:00
abstract：:To examine the physiological significance of plasma ghrelin in generating pulsatile growth hormone (GH) secretion in rats, plasma GH and ghrelin levels were determined in freely moving male rats. Plasma GH was pulsatilely secreted as reported previously. Plasma ghrelin levels were measured by both N-RIA recognizing th...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/s0024-3205(03)00147-4
更新日期：2003-04-18 00:00:00
abstract：:Mast cells were originally considered wandering histiocytes, but are now known to derive from the bone marrow and enter the tissues as immature or precursor cells which then differentiate under micro-environmental influences such as interleukin-3. At least three types of mature mast cells have been identified as seros...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/0024-3205(90)90129-f
更新日期：1990-01-01 00:00:00
abstract：AIMS:To investigate whether the expression of nerve growth factor precursor (proNGF) changes during cardiopulmonary bypass (CPB) and whether neutralizing interleukin-6 (IL-6) during CPB has cardiac benefits. MAIN METHODS:Thirty patients undergoing CPB were recruited and their serum proNGF and troponin-I (TNI) were det...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2017.04.007
更新日期：2017-06-01 00:00:00
abstract：:Recent studies on video game playing have uncovered a wide range of measurable physiological effects on the organism, such as increases in cardiovascular activity and breathing responses. However, the exact source of these effects remains unclear. Given the well-known effects of sound on physiological activity, especi...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2004.11.011
更新日期：2005-04-01 00:00:00
abstract：AIMS:Cold stress has been shown to produce dramatic increases in 2-fluoro-2-deoxy-D-Glucose ((18)FDG) accumulation by brown adipose tissue (BAT) in rodents. However, neither the effects of other types of stress on (18)FDG accumulation nor the effects of stressors on the accumulation of tracers of other aspects of energ...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2011.04.014
更新日期：2011-07-18 00:00:00
abstract：:Loperamide effects on hepatobiliary function, analgesia and gut transit were studied in mice. Varying doses of the antidiarrheal drug, loperamide, were administered to mice by intracerebroventricular, intravenous, subcutaneous and intragastric routes. Gut motility was determined by intestinal transit of India ink, ana...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(94)00609-1
更新日期：1994-01-01 00:00:00
abstract：:Nowadays, endocrine disrupting chemical pollution has become one of the major concerns due to the potential role of these chemicals in provoking endocrine disorders especially type 2 diabetes. As a widespread endocrine disrupting chemical, Bisphenol A, with modest estrogenic activity can exert its detrimental effects ...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/j.lfs.2018.10.044
更新日期：2018-12-01 00:00:00
abstract：:Different receptors mediating the release of endothelium-derived nitric oxide (EDNO) have been identified at endothelial level. In the present study we aimed to characterise, on rabbit aorta by means of pharmacological tools, the generation of EDNO by receptors located on endothelial cell membrane (M3, P2u, P2y) and b...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/s0024-3205(97)01144-2
更新日期：1998-01-01 00:00:00
abstract：:The feasibility of visualizing the heterogeneity of benzodiazepine (BDZ) receptors in the brain of living baboons was investigated using Positron Emission Tomography. Ethyl 8-fluoro-5,6-dihydro-5-methyl 6-oxo-4H-imidazo (1,5-a) (1, 4) benzodiazepine-3-carboxylate (RO 15 1788) labelled by carbon 11 (11C-RO 15 1788) was...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(85)90363-7
更新日期：1985-04-29 00:00:00
abstract：:There is a growing literature indicating that opioid abuse by human addicts and opioid administration to animals have profound effects on the immune system. In the present study, implantation of morphine pellets in mice was associated with reduced phenotypic expression of the cell surface antigens specific to T-lympho...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(92)90607-q
更新日期：1992-01-01 00:00:00
abstract：:The neurological mutant whirler mouse, one of several strains of waltzing mice, may be suitable as an animal model for testing studies relative to hyperkinesis. As in hyperkinetic children, behaviorally the mice are extremely restless, nervous, excitable, irritable and aggressive but also show symptoms of rotation beh...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(85)90404-7
更新日期：1985-08-05 00:00:00
abstract：:Two-dimensional and line-scan analyses of the early phase Ca2+ transients in rat cardiomyocytes were performed with a rapid-scanning laser confocal microscope and fluo-3 to elucidate the mechanism of activation of Ca2+ release from the sarcoplasmic reticulum in atrial myocytes which lack a well developed T-tubular net...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/s0024-3205(01)01436-9
更新日期：2001-12-28 00:00:00
abstract：:The reproductive system effects of cocaine were studied in male rats. The analysis included measurements of circulating levels of luteinizing hormone (LH) and testosterone (T) by radioimmunoassay (RIA). The weights of the testes and sex accessory organs were also assessed and compared with control animals. Dosage leve...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(89)90440-2
更新日期：1989-01-01 00:00:00
abstract：UNLABELLED:Based on preclinical findings, cellular therapy has become a promising therapeutic approach for neonatal hypoxia-ischemia (HI). However, before translation into the clinical setting, new and effective routes of cell delivery must be determined. Intra-arterial (IA) delivery is an attractive route of cellular ...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2013.10.017
更新日期：2014-02-06 00:00:00
abstract：AIMS:Right ventricular failure (RVF) varies significantly from the more common left ventricular failure (LVF). This study was undertaken to determine potential molecular pathways that are important in human right ventricular (RV) function and may mediate RVF. MATERIALS AND METHODS:We analyzed mRNA of human non-failing...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2018.01.021
更新日期：2018-03-01 00:00:00
abstract：:It has been previously shown in anesthetized pigs that intravenous infusion of 2 microg/h of 17beta-estradiol primarily dilated renal, iliac and coronary circulations, while higher doses of the hormone were required to cause vasodilation also in the mesenteric vascular bed. In the same experimental model, a tonic beta...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/s0024-3205(99)00399-9
更新日期：1999-01-01 00:00:00
abstract：AIMS:Fructose administration induces hepatic oxidative stress, insulin resistance, inflammatory and metabolic changes. We tested their potential pathogenic relationship and whether these alterations can be prevented by R/S-α-lipoic acid. MAIN METHODS:Wistar rats received during 21days a commercial diet or the same die...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2015.07.010
更新日期：2015-09-15 00:00:00
abstract：:Macrophages and other host cells activated by interferon-gamma (IFN-gamma) can be induced to form a flavoprotein that converts L-arginine to nitric oxide+L-citrulline. Nitric oxide causes efflux of non-heme iron from neoplastic and infected host cells. In the absence of L-arginine, IFN-gamma-induced infected cells can...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/0024-3205(92)90279-x
更新日期：1992-01-01 00:00:00
abstract：:A natural product betulinic acid (BA) has gained a huge significance in the recent years for its strong cytotoxicity. Surprisingly, in spite of being an interesting cancer protecting agent on a variety of tumor cells, the normal cells and tissues are rarely affected by BA. Betulinic acid and analogues (BAs) generally ...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/j.lfs.2018.07.056
更新日期：2018-09-15 00:00:00
abstract：:Nitric oxide (NO) may play an important regulatory role in airway function. We have, thus, investigated in vitro whether epithelium derived NO may modulate cholinergic neurotransmission, via release of NO in guinea pig trachea, by using L-arginine (L-ARG), a precursor of NO synthesis, and L-N(G)-nitro-arginine-methyl-...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(95)00053-9
更新日期：1995-02-17 00:00:00
abstract：:Collagen is the most abundant protein in mammalian systems; it can be found in organs such as bones, the liver, kidney, heart, teeth, and skin. Collagen provides the necessary structural framework for tissues in which it is found. However, if there are any alterations in the delicate balance of collagen types in the e...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/j.lfs.2019.04.042
更新日期：2019-07-01 00:00:00
abstract：:In order to determine whether CCl4, CBrCl3, CBr4 or CHCl3 undergo oxidative metabolism to electrophilic halogens by liver microsomes, they were incubated with liver microsomes from phenobarbital pretreated rats in the presence of NADPH and 2,6-dimethylphenol. The analysis of the reaction mixtures by capillary gas chro...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(82)90644-0
更新日期：1982-01-11 00:00:00
abstract：AIMS:We investigated the implication of PKA and Epac proteins in the endothelium-independent vasorelaxant effects of cyclic AMP (cAMP). MAIN METHODS:Cytosolic Ca(2+) concentration ([Ca(2+)]c) was measured by fura-2 imaging in rat aortic smooth muscle cells (RASMC). Contraction-relaxation experiments were performed in ...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2016.03.059
更新日期：2016-06-15 00:00:00
abstract：:Trichosanthin (TCS) is a type 1 ribosome-inactivating protein (RIP) effective against HIV-1 and HSV-1 replication. The mechanism of its antiviral activity is not clear. Many believe that it is related to ribosome inactivation. Some RIPs and viral infection affect the phosphorylation of MAPK and Bcl-2 and these protein...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2006.03.047
更新日期：2006-08-22 00:00:00
abstract：:The cholinergic neurotransmission has been implicated in various forms of neural plasticity such as kindling and learning. The present study examined the effects of scopolamine, a muscarinic cholinergic antagonist, on the development of behavioral sensitization to methamphetamine (MA). Rats treated with MA (1 mg/kg, s...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(95)00062-b
更新日期：1995-01-01 00:00:00
abstract：AIMS:Ovarian cancer (OC) is the most lethal gynecologic malignant tumors all over the world. HOX antisense intergenic RNA myeloid 1 (HOTAIRM1) has been reported as an important regulator in multiple tumors. However, the functions of HOTAIRM1 in OC and its possible molecular mechanisms remain unclear. MAIN METHODS:qRT-...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/j.lfs.2020.117296
更新日期：2020-02-15 00:00:00
abstract：:Rats were given the basic lipophilic drug, phenoxybenzamine, in single i.v. doses of 0.4 and 30 mg/kg. The drug was determined in plasma and 7 tissues by a new HPLC method. Adipose tissue reached peak levels after 30 minutes. At that time levels in heart, kidney, and brain were higher than in subcutaneous, epididymal,...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/0024-3205(87)90478-4
更新日期：1987-10-26 00:00:00
abstract：:The centrally mediated pharmacological effects of thyrotropin releasing hormone (TRH), their mechanistic basis and therapeutic implications, along with the possible physiological significance of extrahypothalamic TRH, have been the subject of numerous investigations for over a decade. Despite this effort a holistic pe...
journal_title：Life sciences
pub_type： 杂志文章,评审
doi：10.1016/0024-3205(83)90403-4
更新日期：1983-07-11 00:00:00
abstract：:Extracts of increasing polarity of 6 Venezuelan plants belonging to the Chrysobalanaceae family were tested for possible letal toxicity against Biomphalaria glabrata Say, a snail intermediate hosts of Schistosoma mansoni Sambon. The piscicidal toxicity of the active extracts was also evaluated with the aim of findings...
journal_title：Life sciences
pub_type： 杂志文章
doi：10.1016/s0024-3205(99)00600-1
更新日期：2000-01-01 00:00:00
