Method for assessing X-ray-induced hydroxyl radical-scavenging activity of biological compounds/materials.

abstract：:Kangen-karyu, a prescription containing six herbs, has been shown to achieve its pharmacological effect through oxidative stress-dependent pathways in animal models. The aim of this study is to investigate the relationship between the antioxidative effect and pharmacological mechanisms of Kangen-karyu, specifically it...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hirayama A,Okamoto T,Kimura S,Nagano Y,Matsui H,Tomita T,Oowada S,Aoyagi K

更新日期：2016-05-01 00:00:00

abstract：:We investigated the effect of the sodium glucose cotransporter-2 inhibitor (SGLT-2i) luseogliflozin on skeletal muscle. Eight-week-old mice were fed a standard diet or the standard diet with added luseogliflozin for 8 weeks. The mice were divided into the following four genotype/dietary groups: Db/m mice without SGLT-...

journal_title：Journal of clinical biochemistry and nutrition

authors： Okamura T,Hashimoto Y,Osaka T,Fukuda T,Hamaguchi M,Fukui M

更新日期：2019-07-01 00:00:00

abstract：:We previously reported that the plasma level of endotoxin and colonic expression of IgA in the mouse increased with obstructive jaundice induced by bile duct ligation (BDL). To elucidate the mechanism of the BDL-induced increase, we analyzed the effect of BDL on intestinal flora in wild type and inducible nitric oxide...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hong JY,F Sato E,Nishikawa T,Hiramoto K,Inoue M

更新日期：2009-03-01 00:00:00

abstract：:Although the accumulation of advanced glycation end-products (AGEs) of the Maillard reaction in our body is reported to increase with aging and is enhanced by the pathogenesis of lifestyle-related diseases such as diabetes, routine measurement of AGEs is not applied to regular clinical diagnoses due to the lack of con...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yamanaka M,Matsumura T,Ohno R,Fujiwara Y,Shinagawa M,Sugawa H,Hatano K,Shirakawa J,Kinoshita H,Ito K,Sakata N,Araki E,Nagai R

更新日期：2016-03-01 00:00:00

abstract：:The therapeutic effects of non-thermal plasma are expected in the medical fields, including hemostasis, vascularization, prevention of organ adhesion, and cell proliferation. Cancer is an internal enemy arising from normal tissue in the body. The prognosis of metastatic and recurrent cancers is still poor despite adva...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kajiyama H,Utsumi F,Nakamura K,Tanaka H,Toyokuni S,Hori M,Kikkawa F

更新日期：2017-01-01 00:00:00

abstract：:The effects of inulin on the microbial composition and faecal characteristics in 36 healthy, formula-fed infants (average age 7.7 months) given 3 different daily dosages of native inulin (0.75 g/day, 1.00 g/day, and 1.25 g/day) were studied. At all levels of inulin consumption, a significant (p<0.05) reduction of pote...

journal_title：Journal of clinical biochemistry and nutrition

authors： K W Yap W,Mohamed S,Husni Jamal M,Diederick M,A Manap Y

更新日期：2008-11-01 00:00:00

abstract：:Daily salt intake can be estimated by measuring sodium and creatinine concentrations in spot urine. Excessive salt intake is risk factor for gastric cancer. We examined the correlation between estimated salt intake from spot urine and risk of gastric cancer. This study included gastric cancer patients who underwent tr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Goto A,Nishikawa J,Ito S,Hideura E,Shirasawa T,Hamabe K,Hashimoto S,Okamoto T,Yanai H,Sakaida I

更新日期：2020-01-01 00:00:00

abstract：:Peyer's patches are nodules that play a central role in intestinal immunity. Few studies demonstrate the relationship between the number of Peyer's patches and intestinal polyps. Here we identify a statistically significant inverse correlation between the quantity of Peyer's patches and of the development of intestina...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fujimoto K,Fujii G,Sakurai H,Yoshitome H,Mutoh M,Wada M

更新日期：2015-01-01 00:00:00

abstract：:Nutritional and immunological status of patients with obstructive jaundice is usually severely altered, with high mortality rates. The n-3 polyunsaturate fatty acids (PUFA), particularly eicosapentaenoic acid (EPA, 20:5 n-3), posess potent immunomodulatory activities. Thus, our aim was to compare the plasma phospholip...

journal_title：Journal of clinical biochemistry and nutrition

authors： Popovic T,Ranic M,Bulajic P,Milicevic M,Arsic A,Vucic V,Glibetic M

更新日期：2009-11-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays a crucial role in cancer metastasis. In this study, we evaluated the effect of heat treatment on tumor growth factor-β1 (TGF-β1)-induced EMT in pancreatic cancer cells and tried to ascertain the mechanism related to any observed effects. Human pancreatic cancer cell lines ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kimura-Tsuchiya R,Ishikawa T,Kokura S,Mizushima K,Adachi S,Okajima M,Matsuyama T,Okayama T,Sakamoto N,Katada K,Kamada K,Uchiyama K,Handa O,Takagi T,Yagi N,Naito Y,Itoh Y

更新日期：2014-07-01 00:00:00

abstract：:Although some studies have indicated a correlation between Helicobacter pylori infection and the risk of colorectal neoplasms, these findings have not been consistent and are controversial. This case-control study aimed to investigate the association between endoscopic gastric mucosal atrophy and colorectal polyp occu...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kawahara Y,Kodama M,Mizukami K,Saito T,Hirashita Y,Sonoda A,Fukuda K,Matsunari O,Okamoto K,Ogawa R,Okimoto T,Murakami K

更新日期：2019-09-01 00:00:00

abstract：:Gastrointestinal symptoms are a problematic issue for patients who take low-dose aspirin for long time. We conducted a pilot study to investigate the efficacy of combination therapy with proton pump inhibitor and rebamipide. This was a prospective, randomized, double-blind, placebo-controlled cross-over study. All the...

journal_title：Journal of clinical biochemistry and nutrition

authors： Mizukami K,Murakami K,Hirashita Y,Hisamatsu A,Ogawa R,Uchida M,Nakagawa Y,Okimoto T,Kodama M,Fujioka T

更新日期：2012-11-01 00:00:00

abstract：:Symptomatic differences and the impact of gastroesophageal reflux disease (GERD) have not been clarified in patients with asthma and chronic obstructive pulmonary disease (COPD). The purpose of this study is to assess the differences of GERD symptoms among asthma, COPD, and disease control patients, and determine the ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Shimizu Y,Dobashi K,Kusano M,Mori M

更新日期：2012-03-01 00:00:00

abstract：:Resistance to anti-fungal drugs has become the main cause for increasing incidence rate of Candida infections in pediatric intensive care units (PICU). Zinc supplementation has been shown to exhibit beneficial effects on many pediatric illnesses. This study aimed to investigate the efficacy of zinc supplementation on ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Xie J,Zhu L,Zhu T,Jian Y,Ding Y,Zhou M,Feng X

更新日期：2019-03-01 00:00:00

abstract：:Spironolactone and furosemide, which are used to treat ascites associated with decompensated cirrhosis, are ineffective in treating refractory ascites. Hence, combination therapy with tolvaptan, a vasopressin V2 receptor antagonist, has been approved in Japan. Tolvaptan monotherapy and combination therapy with furosem...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tanabe N,Takami T,Fujisawa K,Matsumoto T,Yamamoto N,Sakaida I

更新日期：2017-07-01 00:00:00

abstract：:Plant sterols are used as food additives to reduce intestinal cholesterol absorption. They also increase fecal neutral sterol (FNS) excretion irrespective of the absorption inhibition. Intestine-mediated reverse cholesterol transport, or trans-intestinal cholesterol efflux (TICE), provides the major part of the increa...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nakano T,Inoue I,Takenaka Y,Ikegami Y,Kotani N,Shimada A,Noda M,Murakoshi T

更新日期：2018-09-01 00:00:00

abstract：:We assessed the effect of multi-species probiotic mixture on the changes in fecal microbiota and irritable bowel syndrome (IBS) symptoms. Eighty-one IBS patients were randomly assigned to receive either probiotic mixture (n = 39; containing Lactobacillus acidophilus, L. rhamnosus, Bifidobacterium breve, B. actis, B. l...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yoon H,Park YS,Lee DH,Seo JG,Shin CM,Kim N

更新日期：2015-09-01 00:00:00

abstract：:Carnitine is a vitamin-like compound that plays important roles in fatty acid β-oxidation and the control of the mitochondrial coenzyme A/acetyl-CoA ratio. However, carnitine is not added to ordinary enteral nutrition or total parenteral nutrition. In this study, we determined the serum carnitine concentrations in sub...

journal_title：Journal of clinical biochemistry and nutrition

authors： Iwamoto J,Honda A,Miyamoto Y,Miyazaki T,Murakami M,Saito Y,Ikegami T,Miyamoto J,Matsuzaki Y

更新日期：2014-11-01 00:00:00

abstract：:Previously, we identified four metabolites of (-)-epicatechin in blood and urine: (-)-epicatechin-3'-O-glucuronide (E3'G), 4'-O-methyl-(-)-epicatechin-3'-O-glucuronide (4'ME3'G), (-)-epicatechin-7-O-glucuronide (E7G), and 3'-O-methyl-(-)-epicatechin-7-O-glucuronide (3'ME7G) (Natsume et al. Free Radical Biol. Med. 34, ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Natsume M,Osakabe N,Yasuda A,Osawa T,Terao J

更新日期：2008-01-01 00:00:00

abstract：:This study aimed to investigate the effects of abundant breast milk intake on rats model of oxygen-induced retinopathy (OIR). Neonatal Sprague-Dawley rats were randomly assigned to expand litters of 7 pups/litter (7-rats group) and 14 pups/litter (14-rats group). They were exposed to 80% oxygen from postnatal day (P) ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsubara M,Saito Y,Nakanishi-Ueda T,Ueda T,Hisamitsu T,Koide R,Takahashi H

更新日期：2014-09-01 00:00:00

abstract：:The purpose of this study was to investigate the effects of antioxidant biofactor (AOB) on reactive oxygen species (ROS). Generation of superoxide radical (O(2) (•-)) and hydroxyl radical ((•)OH) was determined using an electron spin resonance (ESR) spin-trapping method. AOB was added at different concentrations to th...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsui S,Tsujimoto Y,Ozawa T,Matsushima K

更新日期：2011-05-01 00:00:00

abstract：:Biomedical evidence in the last 20 years has shown that the consumption of partially hydrolyzed guar gum may influence lipid and/or carbohydrate metabolism at many levels. Since intestine represents the first interface to interact with dietary partially hydrolyzed guar gum in vivo, we evaluated gene expression profile...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yasukawa Z,Naito Y,Takagi T,Mizushima K,Tokunaga M,Ishihara N,R Juneja L,Yoshikawa T

更新日期：2012-07-01 00:00:00

abstract：:This study investigated the effects of a drink supplement containing Momordica charantia extract from bitter melon on physical fitness and levels of stress hormones during a four-week exercise training program in a hot environment. Ten male tennis players were orally administrated in a four-week (100 ml, 6 times a day...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yook JS,Kwak JJ,Jeong WM,Song YH,Hijioka Y,Honda Y,Kim SE,Ha MS

更新日期：2020-11-01 00:00:00

abstract：:Ubiquinol-10 (QH(2)), the reduced form of Coenzyme Q(10) (CoQ(10)) serves as a potent antioxidant of lipid membranes. Because many antioxidants reveal potent anti-inflammatory effects, the influence of QH(2) on lipopolysaccharide (LPS)-induced pro-inflammatory cytokines and chemokines were determined in the human mono...

journal_title：Journal of clinical biochemistry and nutrition

authors： Schmelzer C,Lorenz G,Rimbach G,Döring F

更新日期：2009-01-01 00:00:00

abstract：:The essential trace element selenium has long been considered to exhibit anti-diabetic and insulin-mimetic properties, but recent epidemiological studies indicated supranutritional selenium intake and high plasma selenium levels as possible risk factors for development of type 2 diabetes, pointing to adverse effects o...

journal_title：Journal of clinical biochemistry and nutrition

authors： Steinbrenner H,Speckmann B,Pinto A,Sies H

更新日期：2011-01-01 00:00:00

abstract：:Consumption of olives (Olea europaea L.) is associated with a low incidence of inflammation-related diseases. Olive fruit is rich in bioactive pentacyclic triterpenoids, mainly maslinic acid. This study, a randomized, double-blind, and placebo-controlled trial, examined the effects of an orally administered maslinic a...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fukumitsu S,Villareal MO,Aida K,Hino A,Hori N,Isoda H,Naito Y

更新日期：2016-11-01 00:00:00

abstract：:The present study was conducted to assess the association between 25-hydroxyvitamin D [25(OH)D], estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) in Korean adults. Data on 4,948 adults aged ≥20 years from the Korean National Health and Nutrition Examination Survey V-3 (2012) w...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kim SG,Kim GS,Lee JH,Moon AE,Yoon H

更新日期：2018-01-01 00:00:00

abstract：:Although atopic dermatitis is known to be closely associated with food antigens, the actual changes in the gastrointestinal tract have not been clarified. The aim of this study was to investigate the macroscopic and histological features of the large intestine in patients with atopic dermatitis. We studied 15 outpatie...

journal_title：Journal of clinical biochemistry and nutrition

authors： Arisawa T,Arisawa S,Yokoi T,Kuroda M,Hirata I,Nakano H

更新日期：2007-01-01 00:00:00

abstract：:Although a large body of literature reported that high intake of vitamin E played a possible role in reducing risk of cardiometabolic diseases, conflicting results were also found in some observational studies due to confounding factors. Hence, we used a Mendelian randomization study as an alternative way to examine t...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fan C,Huang T,Kong X,Zhang X,Zou Z,Xiao J

更新日期：2019-09-01 00:00:00

abstract：:In the present study, we evaluated the relationships of estimated desaturase activities with cardiometabolic risk factors including abdominal obesity, atherogenic lipoprotein phenotype and inflammation in Koreans. Ninety-three healthy volunteers participated in this cross-sectional study. LDL particle size was determi...

journal_title：Journal of clinical biochemistry and nutrition

authors： Do HJ,Chung HK,Moon J,Shin MJ

更新日期：2011-09-01 00:00:00