Effect of Obstructive Jaundice and Nitric Oxide on the Profiles of Intestinal Bacterial Flora in Wild and iNOS Mice.

abstract：:Colon cancer prevalence is high worldwide. O-GlcNAcylation has been associated with tumor growth in various tissues, including the colon; however, its link to carcinogenesis is not fully understood. We investigated the association of O-GlcNAcylation with colon carcinogenesis using a 1,2-dimethylhydrazine/dextran sodiu...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hirata Y,Nakagawa T,Moriwaki K,Koubayashi E,Kakimoto K,Takeuchi T,Inoue T,Higuchi K,Asahi M

更新日期：2018-05-01 00:00:00

abstract：:Bach1 is a transcriptional repressor of heme oxygenase-1 (HO-1, a.k.a. HSP-32), which is an inducible enzyme and has anti-oxidation/anti-inflammatory properties shown in various models of organ injuries. Since oxidative stress plays a pivotal role in the pathogenesis of nonalcoholic steatohepatitis (NASH), HO-1 induct...

journal_title：Journal of clinical biochemistry and nutrition

authors： Inoue M,Tazuma S,Kanno K,Hyogo H,Igarashi K,Chayama K

更新日期：2011-03-01 00:00:00

abstract：:The effects of inulin on the microbial composition and faecal characteristics in 36 healthy, formula-fed infants (average age 7.7 months) given 3 different daily dosages of native inulin (0.75 g/day, 1.00 g/day, and 1.25 g/day) were studied. At all levels of inulin consumption, a significant (p<0.05) reduction of pote...

journal_title：Journal of clinical biochemistry and nutrition

authors： K W Yap W,Mohamed S,Husni Jamal M,Diederick M,A Manap Y

更新日期：2008-11-01 00:00:00

abstract：:The essential trace element selenium has long been considered to exhibit anti-diabetic and insulin-mimetic properties, but recent epidemiological studies indicated supranutritional selenium intake and high plasma selenium levels as possible risk factors for development of type 2 diabetes, pointing to adverse effects o...

journal_title：Journal of clinical biochemistry and nutrition

authors： Steinbrenner H,Speckmann B,Pinto A,Sies H

更新日期：2011-01-01 00:00:00

abstract：:The effects of topical application of Rafflesia hasseltii buds and flowers extract on the rate of wound healing and histology of healed wound were assessed. Four groups of adult male Sprague Dawley rats were experimentally wounded in the posterior neck area. A thin layer of blank placebo was applied topically to wound...

journal_title：Journal of clinical biochemistry and nutrition

authors： Abdulla MA,Ahmed KA,Ali HM,Noor SM,Ismail S

更新日期：2009-11-01 00:00:00

abstract：:Nitric oxide (NO), produced by inducible NO synthase (iNOS) during infection, plays a crucial role in host defense mechanisms. Salmonella typhimurium infection in mice is associated with excessive production of NO from iNOS as a host defense response. An important cytoprotective and antimicrobial function of NO is med...

journal_title：Journal of clinical biochemistry and nutrition

authors： Okamoto T,Khan S,Oyama K,Fujii S,Sawa T,Akaike T

更新日期：2010-01-01 00:00:00

abstract：:Parkinson's disease is a major neurodegenerative disease involving the selective degeneration of dopaminergic neurons and α-synuclein containing Lewy bodies formation in the substantia nigra. Although α-synuclein is a key molecule for both dopaminergic neuron death and the formation of inclusion bodies, the mechanism ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Teraoka M,Nakaso K,Kusumoto C,Katano S,Tajima N,Yamashita A,Zushi T,Ito S,Matsura T

更新日期：2012-09-01 00:00:00

abstract：:It has been reported that levels of soluble intercellular adhesion molecule-1 (ICAM-1) in the blood are elevated in hepatocellular carcinoma patients. In the present study, serial observations of the localization of ICAM-1 in the liver were made by light and electron microscopy in rats with carcinogen-induced cancer. ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsuoka S,Matsumura H,Arakawa Y,Nakamura H,Nirei K,Yamagami H,Ogawa M,Nakajima N,Amaki S,Tanaka N,Moriyama M

更新日期：2009-09-01 00:00:00

abstract：:Previously, we identified four metabolites of (-)-epicatechin in blood and urine: (-)-epicatechin-3'-O-glucuronide (E3'G), 4'-O-methyl-(-)-epicatechin-3'-O-glucuronide (4'ME3'G), (-)-epicatechin-7-O-glucuronide (E7G), and 3'-O-methyl-(-)-epicatechin-7-O-glucuronide (3'ME7G) (Natsume et al. Free Radical Biol. Med. 34, ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Natsume M,Osakabe N,Yasuda A,Osawa T,Terao J

更新日期：2008-01-01 00:00:00

abstract：:Imbalance between reactive oxygen species generation and antioxidant capacity induces a condition known as oxidative stress which is implicated in numerous pathological processes. In this study we evaluated whether natural zeolites chabazite/phillipsite/analcime may affect the levels of different antioxidant enzymes (...

journal_title：Journal of clinical biochemistry and nutrition

authors： Dogliotti G,Malavazos AE,Giacometti S,Solimene U,Fanelli M,Corsi MM,Dozio E

更新日期：2012-05-01 00:00:00

abstract：:We previously reported that type 2 diabetes risk, early impaired glucose tolerance and insulin resistance can be predicted by measuring the fasting levels of certain biomarkers. Here we validated these findings in randomly recruited healthy volunteers (n = 101) based on biomarker expression as well as various non-inva...

journal_title：Journal of clinical biochemistry and nutrition

authors： Umeno A,Fukui T,Hashimoto Y,Kataoka M,Hagihara Y,Nagai H,Horie M,Shichiri M,Yoshino K,Yoshida Y

更新日期：2018-03-01 00:00:00

abstract：:The pathophysiology of hypertension or stroke is associated with an excess of ROS generation in the vascular system, and results in induction of various pathological cascades of cerebrovascular damage. We have demonstrated that electron spin resonance methods using a spin trap or spin probe will be useful for understa...

journal_title：Journal of clinical biochemistry and nutrition

authors： Lee MC

更新日期：2013-01-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is common in patients with many chronic diseases, but has not been well recognized in rheumatoid arthritis (RA). We investigated the prevalence of GERD symptoms in 278 outpatients with RA and their association with such clinical factors as age, sex, height, weight, body mass inde...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nampei A,Shi K,Ebina K,Tomita T,Sugamoto K,Yoshikawa H,Hirao M,Hashimoto J

更新日期：2013-03-01 00:00:00

abstract：:Vitamin E analog, such as α- and γ-tocopherol, can undergo ω-oxidation without cleavage of the chroman ring, and this pathway is responsible for generation of the major urinary vitamin E metabolite, carboxyethyl hydroxychroman. However, it is still unclear how carboxyethyl hydroxychroman is changed in various tissues ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kiyose C,Saito K,Yachi R,Muto C,Igarashi O

更新日期：2015-03-01 00:00:00

abstract：:Consumption of olives (Olea europaea L.) is associated with a low incidence of inflammation-related diseases. Olive fruit is rich in bioactive pentacyclic triterpenoids, mainly maslinic acid. This study, a randomized, double-blind, and placebo-controlled trial, examined the effects of an orally administered maslinic a...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fukumitsu S,Villareal MO,Aida K,Hino A,Hori N,Isoda H,Naito Y

更新日期：2016-11-01 00:00:00

abstract：:A method for correctly assessing hydroxyl radical scavenging activity of antioxidative chemicals and/or biological compounds/materials was proposed. This method can simultaneously assess two factors, i.e. hydroxyl radical-scavenging and 5,5-dimethyl-2-hydroxy-1-pyrrolidine-N-oxide (hydroxyl radical adduct of 5,5-dimet...

journal_title：Journal of clinical biochemistry and nutrition

authors： Ueno M,Nakanishi I,Matsumoto K

更新日期：2013-03-01 00:00:00

abstract：:Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly correlates with clinical disease activity and epithelial injury in ulcerative colitis (UC). Current advances have defined the mechanisms by which neutrophils are activated or migrate across mucosal epithelia. A better understanding ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Naito Y,Takagi T,Yoshikawa T

更新日期：2007-07-01 00:00:00

abstract：:The relationship between Helicobacter pylori (H. pylori) eradication therapy and the risk of developing gastroesophageal reflux disease (GERD) is controversial. We investigated the influence of H. pylori eradication on the risk of GERD by focusing on the quality of life (QOL) and evaluating reflux symptoms. Patients w...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hirata K,Suzuki H,Matsuzaki J,Masaoka T,Saito Y,Nishizawa T,Iwasaki E,Fukuhara S,Okada S,Hibi T

更新日期：2013-03-01 00:00:00

abstract：:Small dense LDL particles (sd-LDL) and body shape index (ABSI), were evaluated in 228 women, living in Naples, Italy (Progetto ATENA). Serum cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, insulin, HOMA, Apo B, hs-CPR and sd-LDL were measured. LDL particle separation was performed by Lipoprint System: se...

journal_title：Journal of clinical biochemistry and nutrition

authors： Gentile M,Iannuzzo G,Mattiello A,Rubba F,Panico S,Rubba P

更新日期：2017-09-01 00:00:00

abstract：:The redox balance of coenzyme Q10 in human plasma is a good marker of oxidative stress because the reduced form of coenzyme Q10 (ubiquinol-10) is very sensitive to oxidation and is quantitatively converted to its oxidized form (ubiquinone-10). Here we describe an HPLC method for simultaneous detection of ubiquinol-10 ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nagase M,Yamamoto Y,Mitsui J,Tsuji S

更新日期：2018-11-01 00:00:00

abstract：:In a variety of experimental models, dietary phytochemicals have been demonstrated to exhibit pronounced and versatile bioactivities. Importantly, the possibility of such phytochemicals for human application has been supported in part by epidemiological surveys, which have demonstrated that frequent ingestion of veget...

journal_title：Journal of clinical biochemistry and nutrition

authors： Murakami A

更新日期：2018-03-01 00:00:00

abstract：:We investigated the effects of treatment with antibodies against tumor necrosis factor (TNF)-α on energy metabolism, nutritional status, serum cytokine levels in patients with Crohn's disease (CD). Twelve patients were enrolled. Resting energy expenditure (REE) levels were measured by indirect calorimetry. Crohn's dis...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nishida N,Sasaki M,Kurihara M,Ichimaru S,Wakita M,Bamba S,Andoh A,Fujiyama Y,Amagai T

更新日期：2013-09-01 00:00:00

abstract：:Plant sterols are used as food additives to reduce intestinal cholesterol absorption. They also increase fecal neutral sterol (FNS) excretion irrespective of the absorption inhibition. Intestine-mediated reverse cholesterol transport, or trans-intestinal cholesterol efflux (TICE), provides the major part of the increa...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nakano T,Inoue I,Takenaka Y,Ikegami Y,Kotani N,Shimada A,Noda M,Murakoshi T

更新日期：2018-09-01 00:00:00

abstract：:There has been considerable public and scientific interest in the use of phytochemicals derived from dietary components to combat human diseases. They are naturally occurring substances found in plants. Ferulic acid (FA) is a phytochemical commonly found in fruits and vegetables such as tomatoes, sweet corn and rice b...

journal_title：Journal of clinical biochemistry and nutrition

authors： Srinivasan M,Sudheer AR,Menon VP

更新日期：2007-03-01 00:00:00

abstract：:We investigated the effect of the sodium glucose cotransporter-2 inhibitor (SGLT-2i) luseogliflozin on skeletal muscle. Eight-week-old mice were fed a standard diet or the standard diet with added luseogliflozin for 8 weeks. The mice were divided into the following four genotype/dietary groups: Db/m mice without SGLT-...

journal_title：Journal of clinical biochemistry and nutrition

authors： Okamura T,Hashimoto Y,Osaka T,Fukuda T,Hamaguchi M,Fukui M

更新日期：2019-07-01 00:00:00

abstract：:Geranylgeranoic acid, a 20-carbon polyprenoic acid (all-trans 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecatetraenoic acid) and its derivatives were previously developed as synthetic "acyclic retinoids" for cancer chemoprevention. Recently, we demonstrated the natural occurrence of geranylgeranoic acid in various medicin...

journal_title：Journal of clinical biochemistry and nutrition

authors： Muraguchi T,Okamoto K,Mitake M,Ogawa H,Shidoji Y

更新日期：2011-07-01 00:00:00

abstract：:THE STUDY EVALUATED AND COMPARED THE DIFFERENCES OF GLUCOSE RESPONSES, INCREMENTAL AREA UNDER CURVE (IAUC), GLYCEMIC INDEX (GI) AND THE CLASSIFICATION OF GI VALUES BETWEEN MEASURED BY BIOCHEMICAL ANALYZER (FUJI AUTOMATIC BIOCHEMISTRY ANALYZER (FAA)) AND THREE GLUCOSE METERS: Accue Chek Advantage (AGM), BREEZE 2 (BGM),...

journal_title：Journal of clinical biochemistry and nutrition

authors： Lin MH,Wu MC,Lin J

更新日期：2010-07-01 00:00:00

abstract：:The aim of this study was to evaluate the influence of sex on serum paraoxonase-1 (PON1) activities and on its relationship with cardiovascular disease risk factors such as overall and central obesity. Arylesterase and lactonase activities of PON1 were assessed in 374 women and 92 men. Both arylesterase and lactonase ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Trentini A,Bellini T,Bonaccorsi G,Cavicchio C,Hanau S,Passaro A,Cervellati C

更新日期：2019-05-01 00:00:00

abstract：:A Using streptozotocin-induced diabetic rats, we examined the effects of zinc supplementation and insulin treatment on the metabolic availability of vitamin A. All diabetic animals exhibited an elevated plasma glucose (>18 mmol/liter) level within 48 h of intravenous streptozotocin injection. The untreated diabetic ra...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tuitoek P,Lakey J,Rajotte R,Ziari S,Tsin A,Basu T

更新日期：1995-01-01 00:00:00

abstract：:The present study was conducted to assess the association between 25-hydroxyvitamin D [25(OH)D], estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) in Korean adults. Data on 4,948 adults aged ≥20 years from the Korean National Health and Nutrition Examination Survey V-3 (2012) w...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kim SG,Kim GS,Lee JH,Moon AE,Yoon H

更新日期：2018-01-01 00:00:00