Expression of intercellular adhesion molecule-1 in the livers of rats treated with diethylnitrosamine.

abstract：:The effects of inulin on the microbial composition and faecal characteristics in 36 healthy, formula-fed infants (average age 7.7 months) given 3 different daily dosages of native inulin (0.75 g/day, 1.00 g/day, and 1.25 g/day) were studied. At all levels of inulin consumption, a significant (p<0.05) reduction of pote...

journal_title：Journal of clinical biochemistry and nutrition

authors： K W Yap W,Mohamed S,Husni Jamal M,Diederick M,A Manap Y

更新日期：2008-11-01 00:00:00

abstract：:It is accepted that pulmonary exposure of rodents to porcine pancreatic elastase (ELT) induces lesions that morphologically resemble human emphysema. Nonetheless, extensive analysis of this model has rarely been conducted. The present study was designed to extensively examine the effects of ELT on lung inflammation, c...

journal_title：Journal of clinical biochemistry and nutrition

authors： Inoue K,Koike E,Yanagisawa R,Takano H

更新日期：2010-03-01 00:00:00

abstract：:Although the accumulation of advanced glycation end-products (AGEs) of the Maillard reaction in our body is reported to increase with aging and is enhanced by the pathogenesis of lifestyle-related diseases such as diabetes, routine measurement of AGEs is not applied to regular clinical diagnoses due to the lack of con...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yamanaka M,Matsumura T,Ohno R,Fujiwara Y,Shinagawa M,Sugawa H,Hatano K,Shirakawa J,Kinoshita H,Ito K,Sakata N,Araki E,Nagai R

更新日期：2016-03-01 00:00:00

abstract：:Anticancer drugs have been reported to damage the intestinal mucosa. We evaluated the effects of caloric intake on the mucosal morphology and immune cells in rats treated with 5-fluorouracil (5-FU). Rats were received a liquid diet plus 5-FU treatment for 8 days as follows: Low calorie group (25 kcal/day with 5-FU), N...

journal_title：Journal of clinical biochemistry and nutrition

authors： Murakami M,Sato N,Tashiro K,Nakamura T,Masunaga H

更新日期：2009-07-01 00:00:00

abstract：:The pathophysiology of hypertension or stroke is associated with an excess of ROS generation in the vascular system, and results in induction of various pathological cascades of cerebrovascular damage. We have demonstrated that electron spin resonance methods using a spin trap or spin probe will be useful for understa...

journal_title：Journal of clinical biochemistry and nutrition

authors： Lee MC

更新日期：2013-01-01 00:00:00

abstract：:Nephrotoxicity is defined as renal dysfunction that arises as result of exposure to external agents such as drugs and environmental chemicals. The present work was undertaken to carry out the phytochemical study and nephroprotective activity of methanolic extract of Casuarina equisetifolia leaves in gentamicin-induced...

journal_title：Journal of clinical biochemistry and nutrition

authors： El-Tantawy WH,Mohamed SA,Abd Al Haleem EN

更新日期：2013-11-01 00:00:00

abstract：:Resistance to anti-fungal drugs has become the main cause for increasing incidence rate of Candida infections in pediatric intensive care units (PICU). Zinc supplementation has been shown to exhibit beneficial effects on many pediatric illnesses. This study aimed to investigate the efficacy of zinc supplementation on ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Xie J,Zhu L,Zhu T,Jian Y,Ding Y,Zhou M,Feng X

更新日期：2019-03-01 00:00:00

abstract：:Imbalance between reactive oxygen species generation and antioxidant capacity induces a condition known as oxidative stress which is implicated in numerous pathological processes. In this study we evaluated whether natural zeolites chabazite/phillipsite/analcime may affect the levels of different antioxidant enzymes (...

journal_title：Journal of clinical biochemistry and nutrition

authors： Dogliotti G,Malavazos AE,Giacometti S,Solimene U,Fanelli M,Corsi MM,Dozio E

更新日期：2012-05-01 00:00:00

abstract：:Proton pump inhibitors (PPIs) are now commonly used for the treatment of acid related diseases such as peptic ulcer and reflux esophagitis. Because of their ability to produce direct inhibition of the proton pump, PPIs provide more sustained increase of the gastric pH than H(2)-receptor (H(2)R) antagonists. Diverse re...

journal_title：Journal of clinical biochemistry and nutrition

authors： Masaoka T,Suzuki H,Hibi T

更新日期：2008-05-01 00:00:00

abstract：:Anti-peptic and anti-inflammatory actions of ecabet sodium might be beneficial in either improving gastritis or relieving dyspeptic symptoms. This study was designed to evaluate the clinical efficacy of ecabet sodium on dyspeptic symptoms and to elucidate the molecular mechanism attributable to symptom relief in patie...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yang Kim H,Hahm KB,Choi MG,Rew JS,Seol SY,Chun HJ,Lee OY,Hong WS

更新日期：2007-11-01 00:00:00

abstract：:Nitidine chloride (NC), a natural, bioactive, phytochemical alkaloid derived from the roots of Zanthoxylum nitidum, has been reported to exhibit anti-tumor activity against various types of cancer. However, the potential therapeutic role of NC in human cervical cancer has not yet been studied. We are the first to repo...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kwon HJ,Kim LH,Ahn CH,Yang IH,Hong KO,Doo Hong S,Shin JA,Cho SD

更新日期：2019-11-01 00:00:00

abstract：:Daily salt intake can be estimated by measuring sodium and creatinine concentrations in spot urine. Excessive salt intake is risk factor for gastric cancer. We examined the correlation between estimated salt intake from spot urine and risk of gastric cancer. This study included gastric cancer patients who underwent tr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Goto A,Nishikawa J,Ito S,Hideura E,Shirasawa T,Hamabe K,Hashimoto S,Okamoto T,Yanai H,Sakaida I

更新日期：2020-01-01 00:00:00

abstract：:Geranylgeranoic acid, a 20-carbon polyprenoic acid (all-trans 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecatetraenoic acid) and its derivatives were previously developed as synthetic "acyclic retinoids" for cancer chemoprevention. Recently, we demonstrated the natural occurrence of geranylgeranoic acid in various medicin...

journal_title：Journal of clinical biochemistry and nutrition

authors： Muraguchi T,Okamoto K,Mitake M,Ogawa H,Shidoji Y

更新日期：2011-07-01 00:00:00

abstract：:Although atopic dermatitis is known to be closely associated with food antigens, the actual changes in the gastrointestinal tract have not been clarified. The aim of this study was to investigate the macroscopic and histological features of the large intestine in patients with atopic dermatitis. We studied 15 outpatie...

journal_title：Journal of clinical biochemistry and nutrition

authors： Arisawa T,Arisawa S,Yokoi T,Kuroda M,Hirata I,Nakano H

更新日期：2007-01-01 00:00:00

abstract：:In a variety of experimental models, dietary phytochemicals have been demonstrated to exhibit pronounced and versatile bioactivities. Importantly, the possibility of such phytochemicals for human application has been supported in part by epidemiological surveys, which have demonstrated that frequent ingestion of veget...

journal_title：Journal of clinical biochemistry and nutrition

authors： Murakami A

更新日期：2018-03-01 00:00:00

abstract：:Symptomatic differences and the impact of gastroesophageal reflux disease (GERD) have not been clarified in patients with asthma and chronic obstructive pulmonary disease (COPD). The purpose of this study is to assess the differences of GERD symptoms among asthma, COPD, and disease control patients, and determine the ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Shimizu Y,Dobashi K,Kusano M,Mori M

更新日期：2012-03-01 00:00:00

abstract：:We previously reported that the plasma level of endotoxin and colonic expression of IgA in the mouse increased with obstructive jaundice induced by bile duct ligation (BDL). To elucidate the mechanism of the BDL-induced increase, we analyzed the effect of BDL on intestinal flora in wild type and inducible nitric oxide...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hong JY,F Sato E,Nishikawa T,Hiramoto K,Inoue M

更新日期：2009-03-01 00:00:00

abstract：:Overexpression of IGF-1R has been demonstrated in gastrointestinal cancers, and its expression is reported as the result of the loss of tumor suppressors. IL-16 is involved in the pathophysiological process of chronic inflammatory diseases. The aim of this study is to determine the changes in the expression of IGF-1R ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nakajima N,Kozu K,Kobayashi S,Nishiyama R,Okubo R,Akai Y,Moriyama M,Kinukawa N

更新日期：2016-07-01 00:00:00

abstract：:In this study, we examined whether compound 48/80 (C48/80), a mast cell degranulator, causes hepatic oxidative damage in rats. Serum and liver biochemical parameters were determined 0.5, 3 or 6 h after a single treatment with C48/80 (0.75 mg/kg). Serum histamine and serotonin levels increased 0.5 h after C48/80 treatm...

journal_title：Journal of clinical biochemistry and nutrition

authors： Ohta Y,Yashiro K,Ohashi K,Horikoshi Y,Kusumoto C,Matsura T

更新日期：2017-05-01 00:00:00

abstract：:This study aimed to investigate the effects of abundant breast milk intake on rats model of oxygen-induced retinopathy (OIR). Neonatal Sprague-Dawley rats were randomly assigned to expand litters of 7 pups/litter (7-rats group) and 14 pups/litter (14-rats group). They were exposed to 80% oxygen from postnatal day (P) ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsubara M,Saito Y,Nakanishi-Ueda T,Ueda T,Hisamitsu T,Koide R,Takahashi H

更新日期：2014-09-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays a crucial role in cancer metastasis. In this study, we evaluated the effect of heat treatment on tumor growth factor-β1 (TGF-β1)-induced EMT in pancreatic cancer cells and tried to ascertain the mechanism related to any observed effects. Human pancreatic cancer cell lines ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kimura-Tsuchiya R,Ishikawa T,Kokura S,Mizushima K,Adachi S,Okajima M,Matsuyama T,Okayama T,Sakamoto N,Katada K,Kamada K,Uchiyama K,Handa O,Takagi T,Yagi N,Naito Y,Itoh Y

更新日期：2014-07-01 00:00:00

abstract：:Omega-3 fatty acids intake is important to maintain muscle mass. However, the relationship between omega-3 fatty acids intake and sarcopenia in elderly patients with type 2 diabetes has been unclear. We used the brief-type self-administered diet history questionnaire for the assessment of habitual food and nutrient in...

journal_title：Journal of clinical biochemistry and nutrition

authors： Okamura T,Hashimoto Y,Miki A,Kaji A,Sakai R,Iwai K,Osaka T,Ushigome E,Hamaguchi M,Yamazaki M,Fukui M

更新日期：2020-05-01 00:00:00

abstract：:Effects of soy isoflavones, genistein and daidzein, on the hepatic gene expression profile and indices for lipid metabolism were compared in rats. In the first experiment (Expt. 1), animals were fed diets containing 2 g/kg of either genistein or daidzein, or a control diet free of isoflavone for 14 days. In the second...

journal_title：Journal of clinical biochemistry and nutrition

authors： Takahashi Y,Odbayar TO,Ide T

更新日期：2009-05-01 00:00:00

abstract：:Antioxidant supplementations are commonly used as an ergogenic aid for physical exercise despite its limited evidence. The study aimed to investigate the effects of a polyphenol mixture and vitamins on exercise endurance capacity. Seventy regularly exercising male participants were randomly assigned to receive oligome...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kang SW,Hahn S,Kim JK,Yang SM,Park BJ,Chul Lee S

更新日期：2012-03-01 00:00:00

abstract：:Spironolactone and furosemide, which are used to treat ascites associated with decompensated cirrhosis, are ineffective in treating refractory ascites. Hence, combination therapy with tolvaptan, a vasopressin V2 receptor antagonist, has been approved in Japan. Tolvaptan monotherapy and combination therapy with furosem...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tanabe N,Takami T,Fujisawa K,Matsumoto T,Yamamoto N,Sakaida I

更新日期：2017-07-01 00:00:00

abstract：:Prostaglandin E2 plays a role in an array of pathophysiological responses, including inflammation, carcinogenesis and so on. Prostaglandin E2 is synthesized from arachidonic acid by the enzymes cyclooxygenase and prostaglandin E synthase. In some pathological conditions, the isozymes cyclooxygenase-2 and microsomal pr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Suzuki-Yamamoto T,Tanaka S,Tsukayama I,Takafuji M,Hanada T,Arakawa T,Kawakami Y,Kimoto M,Takahashi Y

更新日期：2014-11-01 00:00:00

abstract：:Nutritional and immunological status of patients with obstructive jaundice is usually severely altered, with high mortality rates. The n-3 polyunsaturate fatty acids (PUFA), particularly eicosapentaenoic acid (EPA, 20:5 n-3), posess potent immunomodulatory activities. Thus, our aim was to compare the plasma phospholip...

journal_title：Journal of clinical biochemistry and nutrition

authors： Popovic T,Ranic M,Bulajic P,Milicevic M,Arsic A,Vucic V,Glibetic M

更新日期：2009-11-01 00:00:00

abstract：:Citrus bioflavonoids may offer some protection against the early stage of diabetes mellitus and the development of complications. We investigated the effect of hesperidin on blood glucose levels, hepatic glucose-regulating enzyme activities, serum insulin and adiponectin levels, serum and hepatic lipid levels, and par...

journal_title：Journal of clinical biochemistry and nutrition

authors： Akiyama S,Katsumata S,Suzuki K,Ishimi Y,Wu J,Uehara M

更新日期：2010-01-01 00:00:00

abstract：:We examined the effects of citric acid and l-carnitine administration on physical fatigue. In a double-blind, placebo-controlled, 3-way crossover study, 18 healthy volunteers were randomized to oral citric acid (2,700 mg/day), l-carnitine (1,000 mg/day), or placebo for 8 days. The fatigue-inducing physical task consis...

journal_title：Journal of clinical biochemistry and nutrition

authors： Sugino T,Aoyagi S,Shirai T,Kajimoto Y,Kajimoto O

更新日期：2007-11-01 00:00:00

abstract：:So far, little is known about the effect of nutrition and lifestyle on the composition of circulating lipoprotein subfractions. In the current study, we measured the correlations among physical activity, nutrient intake, smoking, body-mass index (BMI), and age with the concentration of triglycerides, cholesterol, phos...

journal_title：Journal of clinical biochemistry and nutrition

authors： Parlesak A,Eckoldt J,Winkler K,Bode CJ,Schäfer C

更新日期：2014-05-01 00:00:00