A comparative analysis of genistein and daidzein in affecting lipid metabolism in rat liver.

abstract：:Ubiquinol-10 (QH(2)), the reduced form of Coenzyme Q(10) (CoQ(10)) serves as a potent antioxidant of lipid membranes. Because many antioxidants reveal potent anti-inflammatory effects, the influence of QH(2) on lipopolysaccharide (LPS)-induced pro-inflammatory cytokines and chemokines were determined in the human mono...

journal_title：Journal of clinical biochemistry and nutrition

authors： Schmelzer C,Lorenz G,Rimbach G,Döring F

更新日期：2009-01-01 00:00:00

abstract：:The redox balance of coenzyme Q10 in human plasma is a good marker of oxidative stress because the reduced form of coenzyme Q10 (ubiquinol-10) is very sensitive to oxidation and is quantitatively converted to its oxidized form (ubiquinone-10). Here we describe an HPLC method for simultaneous detection of ubiquinol-10 ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nagase M,Yamamoto Y,Mitsui J,Tsuji S

更新日期：2018-11-01 00:00:00

abstract：:We investigated the effects of anticancer agents on peripheral blood mononuclear cells for the purpose of providing data to support new translational chemoimmunotherapy regimens. Peripheral-blood mononuclear cells were treated with one of four anticancer agents (5-fluorouracil, irinotecan, cisplatin, and gemcitabine) ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Sakai H,Kokura S,Ishikawa T,Tsuchiya R,Okajima M,Matsuyama T,Adachi S,Katada K,Kamada K,Uchiyama K,Handa O,Takagi T,Yagi N,Naito Y,Yoshikawa T

更新日期：2013-01-01 00:00:00

abstract：:Although some studies have indicated a correlation between Helicobacter pylori infection and the risk of colorectal neoplasms, these findings have not been consistent and are controversial. This case-control study aimed to investigate the association between endoscopic gastric mucosal atrophy and colorectal polyp occu...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kawahara Y,Kodama M,Mizukami K,Saito T,Hirashita Y,Sonoda A,Fukuda K,Matsunari O,Okamoto K,Ogawa R,Okimoto T,Murakami K

更新日期：2019-09-01 00:00:00

abstract：:Overexpression of IGF-1R has been demonstrated in gastrointestinal cancers, and its expression is reported as the result of the loss of tumor suppressors. IL-16 is involved in the pathophysiological process of chronic inflammatory diseases. The aim of this study is to determine the changes in the expression of IGF-1R ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nakajima N,Kozu K,Kobayashi S,Nishiyama R,Okubo R,Akai Y,Moriyama M,Kinukawa N

更新日期：2016-07-01 00:00:00

abstract：:Citrus bioflavonoids may offer some protection against the early stage of diabetes mellitus and the development of complications. We investigated the effect of hesperidin on blood glucose levels, hepatic glucose-regulating enzyme activities, serum insulin and adiponectin levels, serum and hepatic lipid levels, and par...

journal_title：Journal of clinical biochemistry and nutrition

authors： Akiyama S,Katsumata S,Suzuki K,Ishimi Y,Wu J,Uehara M

更新日期：2010-01-01 00:00:00

abstract：:Peyer's patches are nodules that play a central role in intestinal immunity. Few studies demonstrate the relationship between the number of Peyer's patches and intestinal polyps. Here we identify a statistically significant inverse correlation between the quantity of Peyer's patches and of the development of intestina...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fujimoto K,Fujii G,Sakurai H,Yoshitome H,Mutoh M,Wada M

更新日期：2015-01-01 00:00:00

abstract：:Plant sterols are used as food additives to reduce intestinal cholesterol absorption. They also increase fecal neutral sterol (FNS) excretion irrespective of the absorption inhibition. Intestine-mediated reverse cholesterol transport, or trans-intestinal cholesterol efflux (TICE), provides the major part of the increa...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nakano T,Inoue I,Takenaka Y,Ikegami Y,Kotani N,Shimada A,Noda M,Murakoshi T

更新日期：2018-09-01 00:00:00

abstract：:The aim of the study was to evaluate the anti-obesity effects of two types of meju in diet induced obese C57BL/6J mice. Animals were randomly divided into 4 dietary group (n = 10); normal diet, high fat diet with 30% soybean, high fat diet with 30% traditional meju, high fat diet with 30% standardized meju. After 16 w...

journal_title：Journal of clinical biochemistry and nutrition

authors： Bae CR,Kwon DY,Cha YS

更新日期：2014-01-01 00:00:00

abstract：:Small dense LDL particles (sd-LDL) and body shape index (ABSI), were evaluated in 228 women, living in Naples, Italy (Progetto ATENA). Serum cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, insulin, HOMA, Apo B, hs-CPR and sd-LDL were measured. LDL particle separation was performed by Lipoprint System: se...

journal_title：Journal of clinical biochemistry and nutrition

authors： Gentile M,Iannuzzo G,Mattiello A,Rubba F,Panico S,Rubba P

更新日期：2017-09-01 00:00:00

abstract：:Nutritional and immunological status of patients with obstructive jaundice is usually severely altered, with high mortality rates. The n-3 polyunsaturate fatty acids (PUFA), particularly eicosapentaenoic acid (EPA, 20:5 n-3), posess potent immunomodulatory activities. Thus, our aim was to compare the plasma phospholip...

journal_title：Journal of clinical biochemistry and nutrition

authors： Popovic T,Ranic M,Bulajic P,Milicevic M,Arsic A,Vucic V,Glibetic M

更新日期：2009-11-01 00:00:00

abstract：:Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly correlates with clinical disease activity and epithelial injury in ulcerative colitis (UC). Current advances have defined the mechanisms by which neutrophils are activated or migrate across mucosal epithelia. A better understanding ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Naito Y,Takagi T,Yoshikawa T

更新日期：2007-07-01 00:00:00

abstract：:Prostaglandin E2 plays a role in an array of pathophysiological responses, including inflammation, carcinogenesis and so on. Prostaglandin E2 is synthesized from arachidonic acid by the enzymes cyclooxygenase and prostaglandin E synthase. In some pathological conditions, the isozymes cyclooxygenase-2 and microsomal pr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Suzuki-Yamamoto T,Tanaka S,Tsukayama I,Takafuji M,Hanada T,Arakawa T,Kawakami Y,Kimoto M,Takahashi Y

更新日期：2014-11-01 00:00:00

abstract：:Oxidative stress (OS) has been implicated as one of the major underlying mechanisms behind many acute and chronic diseases. However, the measurement of free radicals or their end products is complicated. Isoprostanes, derived from the non-enzymatic peroxidation of arachidonic acid are now considered to be reliable bio...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kaviarasan S,Muniandy S,Qvist R,Ismail IS

更新日期：2009-07-01 00:00:00

abstract：:Gastrointestinal symptoms are a problematic issue for patients who take low-dose aspirin for long time. We conducted a pilot study to investigate the efficacy of combination therapy with proton pump inhibitor and rebamipide. This was a prospective, randomized, double-blind, placebo-controlled cross-over study. All the...

journal_title：Journal of clinical biochemistry and nutrition

authors： Mizukami K,Murakami K,Hirashita Y,Hisamatsu A,Ogawa R,Uchida M,Nakagawa Y,Okimoto T,Kodama M,Fujioka T

更新日期：2012-11-01 00:00:00

abstract：:Although carbon monoxide derived from heme oxygenase has been reported to exert diverse biological actions in mammals, macromolecules responsible for its direct reception and functional outcomes of the gas binding remain largely unknown. Based on our previous results in vivo suggesting carbon monoxide serves as an inh...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yamamoto T,Takano N,Ishiwata K,Suematsu M

更新日期：2011-01-01 00:00:00

abstract：:Recently, we administered fish oil containing eicosapentaenoic acid and docosahexaenoic acid (DHA) to senescence-accelerated mice P8 (SAMP8), in order to investigate the effects on lifespan. Surprisingly, the lifespan of SAMP8 that were fed fish oil was shortened significantly, through a mechanism that likely involved...

journal_title：Journal of clinical biochemistry and nutrition

authors： Sugawara S,Honma T,Ito J,Kijima R,Tsuduki T

更新日期：2013-03-01 00:00:00

abstract：:Spironolactone and furosemide, which are used to treat ascites associated with decompensated cirrhosis, are ineffective in treating refractory ascites. Hence, combination therapy with tolvaptan, a vasopressin V2 receptor antagonist, has been approved in Japan. Tolvaptan monotherapy and combination therapy with furosem...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tanabe N,Takami T,Fujisawa K,Matsumoto T,Yamamoto N,Sakaida I

更新日期：2017-07-01 00:00:00

abstract：:In the present study, we evaluated the relationships of estimated desaturase activities with cardiometabolic risk factors including abdominal obesity, atherogenic lipoprotein phenotype and inflammation in Koreans. Ninety-three healthy volunteers participated in this cross-sectional study. LDL particle size was determi...

journal_title：Journal of clinical biochemistry and nutrition

authors： Do HJ,Chung HK,Moon J,Shin MJ

更新日期：2011-09-01 00:00:00

abstract：:The purpose of this study was to investigate the effects of antioxidant biofactor (AOB) on reactive oxygen species (ROS). Generation of superoxide radical (O(2) (•-)) and hydroxyl radical ((•)OH) was determined using an electron spin resonance (ESR) spin-trapping method. AOB was added at different concentrations to th...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsui S,Tsujimoto Y,Ozawa T,Matsushima K

更新日期：2011-05-01 00:00:00

abstract：:Daily salt intake can be estimated by measuring sodium and creatinine concentrations in spot urine. Excessive salt intake is risk factor for gastric cancer. We examined the correlation between estimated salt intake from spot urine and risk of gastric cancer. This study included gastric cancer patients who underwent tr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Goto A,Nishikawa J,Ito S,Hideura E,Shirasawa T,Hamabe K,Hashimoto S,Okamoto T,Yanai H,Sakaida I

更新日期：2020-01-01 00:00:00

abstract：:Selenoprotein P (encoded by SELENOP) contains the essential trace element selenium in the form of selenocysteine, which is an analog of cysteine that contains selenium instead of sulfur. Selenoprotein P is a major selenium-containing protein in human plasma and is mainly synthesized in the liver. It functions as a sel...

journal_title：Journal of clinical biochemistry and nutrition

authors： Saito Y

更新日期：2020-01-01 00:00:00

abstract：:We investigated the effect of the sodium glucose cotransporter-2 inhibitor (SGLT-2i) luseogliflozin on skeletal muscle. Eight-week-old mice were fed a standard diet or the standard diet with added luseogliflozin for 8 weeks. The mice were divided into the following four genotype/dietary groups: Db/m mice without SGLT-...

journal_title：Journal of clinical biochemistry and nutrition

authors： Okamura T,Hashimoto Y,Osaka T,Fukuda T,Hamaguchi M,Fukui M

更新日期：2019-07-01 00:00:00

abstract：:The effects of topical application of Rafflesia hasseltii buds and flowers extract on the rate of wound healing and histology of healed wound were assessed. Four groups of adult male Sprague Dawley rats were experimentally wounded in the posterior neck area. A thin layer of blank placebo was applied topically to wound...

journal_title：Journal of clinical biochemistry and nutrition

authors： Abdulla MA,Ahmed KA,Ali HM,Noor SM,Ismail S

更新日期：2009-11-01 00:00:00

abstract：:It has been reported that levels of soluble intercellular adhesion molecule-1 (ICAM-1) in the blood are elevated in hepatocellular carcinoma patients. In the present study, serial observations of the localization of ICAM-1 in the liver were made by light and electron microscopy in rats with carcinogen-induced cancer. ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsuoka S,Matsumura H,Arakawa Y,Nakamura H,Nirei K,Yamagami H,Ogawa M,Nakajima N,Amaki S,Tanaka N,Moriyama M

更新日期：2009-09-01 00:00:00

abstract：:Parkinson's disease is a major neurodegenerative disease involving the selective degeneration of dopaminergic neurons and α-synuclein containing Lewy bodies formation in the substantia nigra. Although α-synuclein is a key molecule for both dopaminergic neuron death and the formation of inclusion bodies, the mechanism ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Teraoka M,Nakaso K,Kusumoto C,Katano S,Tajima N,Yamashita A,Zushi T,Ito S,Matsura T

更新日期：2012-09-01 00:00:00

abstract：:This study investigated the effects of a drink supplement containing Momordica charantia extract from bitter melon on physical fitness and levels of stress hormones during a four-week exercise training program in a hot environment. Ten male tennis players were orally administrated in a four-week (100 ml, 6 times a day...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yook JS,Kwak JJ,Jeong WM,Song YH,Hijioka Y,Honda Y,Kim SE,Ha MS

更新日期：2020-11-01 00:00:00

abstract：:The present study was conducted to assess the association between 25-hydroxyvitamin D [25(OH)D], estimated glomerular filtration rate (eGFR) and urine microalbumin/creatinine ratio (uACR) in Korean adults. Data on 4,948 adults aged ≥20 years from the Korean National Health and Nutrition Examination Survey V-3 (2012) w...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kim SG,Kim GS,Lee JH,Moon AE,Yoon H

更新日期：2018-01-01 00:00:00

abstract：:It is accepted that pulmonary exposure of rodents to porcine pancreatic elastase (ELT) induces lesions that morphologically resemble human emphysema. Nonetheless, extensive analysis of this model has rarely been conducted. The present study was designed to extensively examine the effects of ELT on lung inflammation, c...

journal_title：Journal of clinical biochemistry and nutrition

authors： Inoue K,Koike E,Yanagisawa R,Takano H

更新日期：2010-03-01 00:00:00

abstract：:Nitidine chloride (NC), a natural, bioactive, phytochemical alkaloid derived from the roots of Zanthoxylum nitidum, has been reported to exhibit anti-tumor activity against various types of cancer. However, the potential therapeutic role of NC in human cervical cancer has not yet been studied. We are the first to repo...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kwon HJ,Kim LH,Ahn CH,Yang IH,Hong KO,Doo Hong S,Shin JA,Cho SD

更新日期：2019-11-01 00:00:00