The inhibitory effect of heat treatment against epithelial-mesenchymal transition (EMT) in human pancreatic adenocarcinoma cell lines.

abstract：:Anticancer drugs have been reported to damage the intestinal mucosa. We evaluated the effects of caloric intake on the mucosal morphology and immune cells in rats treated with 5-fluorouracil (5-FU). Rats were received a liquid diet plus 5-FU treatment for 8 days as follows: Low calorie group (25 kcal/day with 5-FU), N...

journal_title：Journal of clinical biochemistry and nutrition

authors： Murakami M,Sato N,Tashiro K,Nakamura T,Masunaga H

更新日期：2009-07-01 00:00:00

abstract：:Antioxidant supplementations are commonly used as an ergogenic aid for physical exercise despite its limited evidence. The study aimed to investigate the effects of a polyphenol mixture and vitamins on exercise endurance capacity. Seventy regularly exercising male participants were randomly assigned to receive oligome...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kang SW,Hahn S,Kim JK,Yang SM,Park BJ,Chul Lee S

更新日期：2012-03-01 00:00:00

abstract：:Parkinson's disease is a major neurodegenerative disease involving the selective degeneration of dopaminergic neurons and α-synuclein containing Lewy bodies formation in the substantia nigra. Although α-synuclein is a key molecule for both dopaminergic neuron death and the formation of inclusion bodies, the mechanism ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Teraoka M,Nakaso K,Kusumoto C,Katano S,Tajima N,Yamashita A,Zushi T,Ito S,Matsura T

更新日期：2012-09-01 00:00:00

abstract：:The effects of topical application of Rafflesia hasseltii buds and flowers extract on the rate of wound healing and histology of healed wound were assessed. Four groups of adult male Sprague Dawley rats were experimentally wounded in the posterior neck area. A thin layer of blank placebo was applied topically to wound...

journal_title：Journal of clinical biochemistry and nutrition

authors： Abdulla MA,Ahmed KA,Ali HM,Noor SM,Ismail S

更新日期：2009-11-01 00:00:00

abstract：:Nephrotoxicity is defined as renal dysfunction that arises as result of exposure to external agents such as drugs and environmental chemicals. The present work was undertaken to carry out the phytochemical study and nephroprotective activity of methanolic extract of Casuarina equisetifolia leaves in gentamicin-induced...

journal_title：Journal of clinical biochemistry and nutrition

authors： El-Tantawy WH,Mohamed SA,Abd Al Haleem EN

更新日期：2013-11-01 00:00:00

abstract：:We examined the effects of citric acid and l-carnitine administration on physical fatigue. In a double-blind, placebo-controlled, 3-way crossover study, 18 healthy volunteers were randomized to oral citric acid (2,700 mg/day), l-carnitine (1,000 mg/day), or placebo for 8 days. The fatigue-inducing physical task consis...

journal_title：Journal of clinical biochemistry and nutrition

authors： Sugino T,Aoyagi S,Shirai T,Kajimoto Y,Kajimoto O

更新日期：2007-11-01 00:00:00

abstract：:Geranylgeranoic acid, a 20-carbon polyprenoic acid (all-trans 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecatetraenoic acid) and its derivatives were previously developed as synthetic "acyclic retinoids" for cancer chemoprevention. Recently, we demonstrated the natural occurrence of geranylgeranoic acid in various medicin...

journal_title：Journal of clinical biochemistry and nutrition

authors： Muraguchi T,Okamoto K,Mitake M,Ogawa H,Shidoji Y

更新日期：2011-07-01 00:00:00

abstract：:The relationship between Helicobacter pylori (H. pylori) eradication therapy and the risk of developing gastroesophageal reflux disease (GERD) is controversial. We investigated the influence of H. pylori eradication on the risk of GERD by focusing on the quality of life (QOL) and evaluating reflux symptoms. Patients w...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hirata K,Suzuki H,Matsuzaki J,Masaoka T,Saito Y,Nishizawa T,Iwasaki E,Fukuhara S,Okada S,Hibi T

更新日期：2013-03-01 00:00:00

abstract：:This study aimed to consider the significance of breast milk in preventing oxidative stress by comparing total antioxidant capacity (TAC) in breast milk and formula milk for premature infants, demonstrating the relationship between TAC in breast milk and postnatal age in days. We used the biological anti-oxidant poten...

journal_title：Journal of clinical biochemistry and nutrition

authors： Ezaki S,Ito T,Suzuki K,Tamura M

更新日期：2008-03-01 00:00:00

abstract：:The amount of phosphorus contained in food as food additives is currently increasing and a high intake of phosphorus can cause various diseases. To determine the effects of a prolonged high phosphorus diet, here we investigated the phosphorus and calcium balance and expression of type IIa sodium-dependent phosphate tr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tani Y,Sato T,Yamanaka-Okumura H,Yamamoto H,Arai H,Sawada N,Genjida K,Taketani Y,Takeda E

更新日期：2007-05-01 00:00:00

abstract：:Although carbon monoxide derived from heme oxygenase has been reported to exert diverse biological actions in mammals, macromolecules responsible for its direct reception and functional outcomes of the gas binding remain largely unknown. Based on our previous results in vivo suggesting carbon monoxide serves as an inh...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yamamoto T,Takano N,Ishiwata K,Suematsu M

更新日期：2011-01-01 00:00:00

abstract：:Reduced coenzyme Q(10) (CoQ(10)H(2)) is known as a potent antioxidant in biological systems. However, it is not yet known whether CoQ(9)H(2) could act as an antioxidant in human cells. The aim of this study is to assess whether exogenously added CoQ(9) can protect human liver cells against injuries induced by a water-...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kusumoto C,Kinugawa T,Morikawa H,Teraoka M,Nishida T,Murawaki Y,Yamada K,Matsura T

更新日期：2010-05-01 00:00:00

abstract：:The present study was conducted in order to determine whether oxidative stress during aging involves dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis in association with the emergence of cognitive deficits. When young rats were subjected to oxidative stress in the form of hyperoxia, thiobarbituric acid rea...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kobayashi N,Machida T,Takahashi T,Takatsu H,Shinkai T,Abe K,Urano S

更新日期：2009-09-01 00:00:00

abstract：:Mammals have the biological clocks with approximately 24 h-rhythm. Energy metabolism including glucose metabolism is regulated by the biological clocks. Glucose metabolism is affected by not only meal volume and its energy but also meal timing. We have reported that cacao liquor procyanidin-rich extract (CLPr) amelior...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hironao KY,Ashida H,Yamashita Y

更新日期：2020-07-01 00:00:00

abstract：:The fatty acid composition of serum phospholipids were analyzed in 20 patients with alcoholic liver cirrhosis (11 with malnutrition and 9 with acceptable nutritional status); 25 healthy age and sex-matched adults were used as controls. Cirrhotic patients showed higher levels of palmitic acid and total saturated fatty ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Ristić-Medić D,Takić M,Vučić V,Kandić D,Kostić N,Glibetić M

更新日期：2013-07-01 00:00:00

abstract：:Bach1 is a transcriptional repressor of heme oxygenase-1 (HO-1, a.k.a. HSP-32), which is an inducible enzyme and has anti-oxidation/anti-inflammatory properties shown in various models of organ injuries. Since oxidative stress plays a pivotal role in the pathogenesis of nonalcoholic steatohepatitis (NASH), HO-1 induct...

journal_title：Journal of clinical biochemistry and nutrition

authors： Inoue M,Tazuma S,Kanno K,Hyogo H,Igarashi K,Chayama K

更新日期：2011-03-01 00:00:00

abstract：:Daily salt intake can be estimated by measuring sodium and creatinine concentrations in spot urine. Excessive salt intake is risk factor for gastric cancer. We examined the correlation between estimated salt intake from spot urine and risk of gastric cancer. This study included gastric cancer patients who underwent tr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Goto A,Nishikawa J,Ito S,Hideura E,Shirasawa T,Hamabe K,Hashimoto S,Okamoto T,Yanai H,Sakaida I

更新日期：2020-01-01 00:00:00

abstract：:Coenzyme Q10 (CoQ10) is synthesized in almost all human tissues and presumably involved in age-related alterations and diseases. Here, we examined the impact of aging and sex on the serum CoQ10 status in 860 European adults ranging in age from 18 to 82 years. We identified an inverse U-shaped relationship between CoQ1...

journal_title：Journal of clinical biochemistry and nutrition

authors： Niklowitz P,Onur S,Fischer A,Laudes M,Palussen M,Menke T,Döring F

更新日期：2016-05-01 00:00:00

abstract：:Inflammatory changes in the gastric mucosa are commonly observed in Japanese patients with functional dyspepsia (FD). However, detailed data regarding the possible association between the genetic factors of inflammation related molecules and FD are not available. Toll like receptor 2 (TLR2) and mannan-binding lectin (...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tahara T,Shibata T,Wang F,Yamashita H,Hirata I,Arisawa T

更新日期：2010-11-01 00:00:00

abstract：:It has been reported that levels of soluble intercellular adhesion molecule-1 (ICAM-1) in the blood are elevated in hepatocellular carcinoma patients. In the present study, serial observations of the localization of ICAM-1 in the liver were made by light and electron microscopy in rats with carcinogen-induced cancer. ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsuoka S,Matsumura H,Arakawa Y,Nakamura H,Nirei K,Yamagami H,Ogawa M,Nakajima N,Amaki S,Tanaka N,Moriyama M

更新日期：2009-09-01 00:00:00

abstract：:Symptomatic differences and the impact of gastroesophageal reflux disease (GERD) have not been clarified in patients with asthma and chronic obstructive pulmonary disease (COPD). The purpose of this study is to assess the differences of GERD symptoms among asthma, COPD, and disease control patients, and determine the ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Shimizu Y,Dobashi K,Kusano M,Mori M

更新日期：2012-03-01 00:00:00

abstract：:Imbalance between reactive oxygen species generation and antioxidant capacity induces a condition known as oxidative stress which is implicated in numerous pathological processes. In this study we evaluated whether natural zeolites chabazite/phillipsite/analcime may affect the levels of different antioxidant enzymes (...

journal_title：Journal of clinical biochemistry and nutrition

authors： Dogliotti G,Malavazos AE,Giacometti S,Solimene U,Fanelli M,Corsi MM,Dozio E

更新日期：2012-05-01 00:00:00

abstract：:Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly correlates with clinical disease activity and epithelial injury in ulcerative colitis (UC). Current advances have defined the mechanisms by which neutrophils are activated or migrate across mucosal epithelia. A better understanding ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Naito Y,Takagi T,Yoshikawa T

更新日期：2007-07-01 00:00:00

abstract：:Ubiquinol-10 (QH(2)), the reduced form of Coenzyme Q(10) (CoQ(10)) serves as a potent antioxidant of lipid membranes. Because many antioxidants reveal potent anti-inflammatory effects, the influence of QH(2) on lipopolysaccharide (LPS)-induced pro-inflammatory cytokines and chemokines were determined in the human mono...

journal_title：Journal of clinical biochemistry and nutrition

authors： Schmelzer C,Lorenz G,Rimbach G,Döring F

更新日期：2009-01-01 00:00:00

abstract：:Cardiovascular disease is a major cause of death among hemodialysis patients. Hyperphosphatemia induces cardiovascular disease through vascular endothelial dysfunction and calcification. Repetition of a short-term excessive-phosphorus (P) diet causes transient elevations in plasma P and subsequent vascular endothelial...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tani M,Tanaka S,Takamiya K,Sakaue M,Ito M

更新日期：2020-03-01 00:00:00

abstract：:Changes in l-arginine metabolism, including increased arginase levels and decreased nitric oxide production, are involved in the pathophysiology of asthma. In this study, using an intranasal mite-induced NC/Nga mouse model of asthma, we examined whether administration of l-arginine ameliorated airway hyperresponsivene...

journal_title：Journal of clinical biochemistry and nutrition

authors： Zhang R,Kubo M,Murakami I,Setiawan H,Takemoto K,Inoue K,Fujikura Y,Ogino K

更新日期：2015-05-01 00:00:00

abstract：:There has been considerable public and scientific interest in the use of phytochemicals derived from dietary components to combat human diseases. They are naturally occurring substances found in plants. Ferulic acid (FA) is a phytochemical commonly found in fruits and vegetables such as tomatoes, sweet corn and rice b...

journal_title：Journal of clinical biochemistry and nutrition

authors： Srinivasan M,Sudheer AR,Menon VP

更新日期：2007-03-01 00:00:00

abstract：:Carnitine is a vitamin-like compound that plays important roles in fatty acid β-oxidation and the control of the mitochondrial coenzyme A/acetyl-CoA ratio. However, carnitine is not added to ordinary enteral nutrition or total parenteral nutrition. In this study, we determined the serum carnitine concentrations in sub...

journal_title：Journal of clinical biochemistry and nutrition

authors： Iwamoto J,Honda A,Miyamoto Y,Miyazaki T,Murakami M,Saito Y,Ikegami T,Miyamoto J,Matsuzaki Y

更新日期：2014-11-01 00:00:00

abstract：:So far, little is known about the effect of nutrition and lifestyle on the composition of circulating lipoprotein subfractions. In the current study, we measured the correlations among physical activity, nutrient intake, smoking, body-mass index (BMI), and age with the concentration of triglycerides, cholesterol, phos...

journal_title：Journal of clinical biochemistry and nutrition

authors： Parlesak A,Eckoldt J,Winkler K,Bode CJ,Schäfer C

更新日期：2014-05-01 00:00:00

abstract：:Although a large body of literature reported that high intake of vitamin E played a possible role in reducing risk of cardiometabolic diseases, conflicting results were also found in some observational studies due to confounding factors. Hence, we used a Mendelian randomization study as an alternative way to examine t...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fan C,Huang T,Kong X,Zhang X,Zou Z,Xiao J

更新日期：2019-09-01 00:00:00