Changes of energy metabolism, nutritional status and serum cytokine levels in patients with Crohn's disease after anti-tumor necrosis factor-α therapy.

abstract：:Vitamin E analog, such as α- and γ-tocopherol, can undergo ω-oxidation without cleavage of the chroman ring, and this pathway is responsible for generation of the major urinary vitamin E metabolite, carboxyethyl hydroxychroman. However, it is still unclear how carboxyethyl hydroxychroman is changed in various tissues ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kiyose C,Saito K,Yachi R,Muto C,Igarashi O

更新日期：2015-03-01 00:00:00

abstract：:We examined the effects of citric acid and l-carnitine administration on physical fatigue. In a double-blind, placebo-controlled, 3-way crossover study, 18 healthy volunteers were randomized to oral citric acid (2,700 mg/day), l-carnitine (1,000 mg/day), or placebo for 8 days. The fatigue-inducing physical task consis...

journal_title：Journal of clinical biochemistry and nutrition

authors： Sugino T,Aoyagi S,Shirai T,Kajimoto Y,Kajimoto O

更新日期：2007-11-01 00:00:00

abstract：:Peyer's patches are nodules that play a central role in intestinal immunity. Few studies demonstrate the relationship between the number of Peyer's patches and intestinal polyps. Here we identify a statistically significant inverse correlation between the quantity of Peyer's patches and of the development of intestina...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fujimoto K,Fujii G,Sakurai H,Yoshitome H,Mutoh M,Wada M

更新日期：2015-01-01 00:00:00

abstract：:Anti-peptic and anti-inflammatory actions of ecabet sodium might be beneficial in either improving gastritis or relieving dyspeptic symptoms. This study was designed to evaluate the clinical efficacy of ecabet sodium on dyspeptic symptoms and to elucidate the molecular mechanism attributable to symptom relief in patie...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yang Kim H,Hahm KB,Choi MG,Rew JS,Seol SY,Chun HJ,Lee OY,Hong WS

更新日期：2007-11-01 00:00:00

abstract：:Ubiquinol-10 (QH(2)), the reduced form of Coenzyme Q(10) (CoQ(10)) serves as a potent antioxidant of lipid membranes. Because many antioxidants reveal potent anti-inflammatory effects, the influence of QH(2) on lipopolysaccharide (LPS)-induced pro-inflammatory cytokines and chemokines were determined in the human mono...

journal_title：Journal of clinical biochemistry and nutrition

authors： Schmelzer C,Lorenz G,Rimbach G,Döring F

更新日期：2009-01-01 00:00:00

abstract：:A Using streptozotocin-induced diabetic rats, we examined the effects of zinc supplementation and insulin treatment on the metabolic availability of vitamin A. All diabetic animals exhibited an elevated plasma glucose (>18 mmol/liter) level within 48 h of intravenous streptozotocin injection. The untreated diabetic ra...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tuitoek P,Lakey J,Rajotte R,Ziari S,Tsin A,Basu T

更新日期：1995-01-01 00:00:00

abstract：:Previously, we identified four metabolites of (-)-epicatechin in blood and urine: (-)-epicatechin-3'-O-glucuronide (E3'G), 4'-O-methyl-(-)-epicatechin-3'-O-glucuronide (4'ME3'G), (-)-epicatechin-7-O-glucuronide (E7G), and 3'-O-methyl-(-)-epicatechin-7-O-glucuronide (3'ME7G) (Natsume et al. Free Radical Biol. Med. 34, ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Natsume M,Osakabe N,Yasuda A,Osawa T,Terao J

更新日期：2008-01-01 00:00:00

abstract：:We investigated the effects of anticancer agents on peripheral blood mononuclear cells for the purpose of providing data to support new translational chemoimmunotherapy regimens. Peripheral-blood mononuclear cells were treated with one of four anticancer agents (5-fluorouracil, irinotecan, cisplatin, and gemcitabine) ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Sakai H,Kokura S,Ishikawa T,Tsuchiya R,Okajima M,Matsuyama T,Adachi S,Katada K,Kamada K,Uchiyama K,Handa O,Takagi T,Yagi N,Naito Y,Yoshikawa T

更新日期：2013-01-01 00:00:00

abstract：:We previously reported that type 2 diabetes risk, early impaired glucose tolerance and insulin resistance can be predicted by measuring the fasting levels of certain biomarkers. Here we validated these findings in randomly recruited healthy volunteers (n = 101) based on biomarker expression as well as various non-inva...

journal_title：Journal of clinical biochemistry and nutrition

authors： Umeno A,Fukui T,Hashimoto Y,Kataoka M,Hagihara Y,Nagai H,Horie M,Shichiri M,Yoshino K,Yoshida Y

更新日期：2018-03-01 00:00:00

abstract：:The effects of inulin on the microbial composition and faecal characteristics in 36 healthy, formula-fed infants (average age 7.7 months) given 3 different daily dosages of native inulin (0.75 g/day, 1.00 g/day, and 1.25 g/day) were studied. At all levels of inulin consumption, a significant (p<0.05) reduction of pote...

journal_title：Journal of clinical biochemistry and nutrition

authors： K W Yap W,Mohamed S,Husni Jamal M,Diederick M,A Manap Y

更新日期：2008-11-01 00:00:00

abstract：:Nephrotoxicity is defined as renal dysfunction that arises as result of exposure to external agents such as drugs and environmental chemicals. The present work was undertaken to carry out the phytochemical study and nephroprotective activity of methanolic extract of Casuarina equisetifolia leaves in gentamicin-induced...

journal_title：Journal of clinical biochemistry and nutrition

authors： El-Tantawy WH,Mohamed SA,Abd Al Haleem EN

更新日期：2013-11-01 00:00:00

abstract：:It has been reported that levels of soluble intercellular adhesion molecule-1 (ICAM-1) in the blood are elevated in hepatocellular carcinoma patients. In the present study, serial observations of the localization of ICAM-1 in the liver were made by light and electron microscopy in rats with carcinogen-induced cancer. ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsuoka S,Matsumura H,Arakawa Y,Nakamura H,Nirei K,Yamagami H,Ogawa M,Nakajima N,Amaki S,Tanaka N,Moriyama M

更新日期：2009-09-01 00:00:00

abstract：:Proton pump inhibitors are the first-line treatment for reflux esophagitis. Because severe reflux esophagitis has very low prevalence in Japan, little is known about the effectiveness of proton pump inhibitors in these patients. This prospective multicenter study assessed the effectiveness of proton pump inhibitors fo...

journal_title：Journal of clinical biochemistry and nutrition

authors： Mizuno H,Matsuhashi N,Sakaguchi M,Inoue S,Nakada K,Higuchi K,Haruma K,Joh T

更新日期：2015-11-01 00:00:00

abstract：:Monascus purpureus is a red dye derived from yeast rice and has been used as color additives for food in East Asia. Monascus purpureus consists of several bioactive components. Some of these components work as a radical scavenger, thus monascus purpureus would also eliminate reactive oxygen species. Cancer cells maint...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kurokawa H,Ito H,Matsui H

更新日期：2017-11-01 00:00:00

abstract：:This study investigated the effects of a drink supplement containing Momordica charantia extract from bitter melon on physical fitness and levels of stress hormones during a four-week exercise training program in a hot environment. Ten male tennis players were orally administrated in a four-week (100 ml, 6 times a day...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yook JS,Kwak JJ,Jeong WM,Song YH,Hijioka Y,Honda Y,Kim SE,Ha MS

更新日期：2020-11-01 00:00:00

abstract：:This study aimed to investigate the effects of abundant breast milk intake on rats model of oxygen-induced retinopathy (OIR). Neonatal Sprague-Dawley rats were randomly assigned to expand litters of 7 pups/litter (7-rats group) and 14 pups/litter (14-rats group). They were exposed to 80% oxygen from postnatal day (P) ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Matsubara M,Saito Y,Nakanishi-Ueda T,Ueda T,Hisamitsu T,Koide R,Takahashi H

更新日期：2014-09-01 00:00:00

abstract：:Biomedical evidence in the last 20 years has shown that the consumption of partially hydrolyzed guar gum may influence lipid and/or carbohydrate metabolism at many levels. Since intestine represents the first interface to interact with dietary partially hydrolyzed guar gum in vivo, we evaluated gene expression profile...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yasukawa Z,Naito Y,Takagi T,Mizushima K,Tokunaga M,Ishihara N,R Juneja L,Yoshikawa T

更新日期：2012-07-01 00:00:00

abstract：:N(ε)-(Hexanoyl)lysine, formed by the reaction of lysine with n-6 lipid hydroperoxide, is a lipid peroxidation marker during the initial stage of oxidative stress. The aim of the present study is to indentify N(ε)-(hexanoyl)lysine-modified proteins in neoplastic transformed gastric mucosal cells by N-methyl-N'-nitro-N-...

journal_title：Journal of clinical biochemistry and nutrition

authors： Okada H,Naito Y,Takagi T,Takaoka M,Oya-Ito T,Fukumoto K,Uchiyama K,Handa O,Kokura S,Nagano Y,Matsui H,Kato Y,Osawa T,Yoshikawa T

更新日期：2012-01-01 00:00:00

abstract：:In a variety of experimental models, dietary phytochemicals have been demonstrated to exhibit pronounced and versatile bioactivities. Importantly, the possibility of such phytochemicals for human application has been supported in part by epidemiological surveys, which have demonstrated that frequent ingestion of veget...

journal_title：Journal of clinical biochemistry and nutrition

authors： Murakami A

更新日期：2018-03-01 00:00:00

abstract：:Osteoclasts play a major role in bone resorption. Several functional food components, such as soy isoflavones and carotenoids, are reported to inhibit osteoclast formation. However, the cooperative effect of functional foods or their constituents on bone metabolism has not been clarified. This study aimed to investiga...

journal_title：Journal of clinical biochemistry and nutrition

authors： Tadaishi M,Nishide Y,Tousen Y,Kruger MC,Ishimi Y

更新日期：2014-03-01 00:00:00

abstract：:Reactive oxygen species attack several living organs and induce cell death. Previously, we found axonal/dendrite degeneration before the induction of cell death in hydrogen peroxide-treated neuroblastoma: N1E-115 cells and primary neurons. This phenomenon may be connected with membrane oxidation, microtubule destabili...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fukui K,Okihiro S,Ohfuchi Y,Hashimoto M,Kato Y,Yoshida N,Mochizuki K,Tsumoto H,Miura Y

更新日期：2019-01-01 00:00:00

abstract：:Nitric oxide (NO), produced by inducible NO synthase (iNOS) during infection, plays a crucial role in host defense mechanisms. Salmonella typhimurium infection in mice is associated with excessive production of NO from iNOS as a host defense response. An important cytoprotective and antimicrobial function of NO is med...

journal_title：Journal of clinical biochemistry and nutrition

authors： Okamoto T,Khan S,Oyama K,Fujii S,Sawa T,Akaike T

更新日期：2010-01-01 00:00:00

abstract：:Although atopic dermatitis is known to be closely associated with food antigens, the actual changes in the gastrointestinal tract have not been clarified. The aim of this study was to investigate the macroscopic and histological features of the large intestine in patients with atopic dermatitis. We studied 15 outpatie...

journal_title：Journal of clinical biochemistry and nutrition

authors： Arisawa T,Arisawa S,Yokoi T,Kuroda M,Hirata I,Nakano H

更新日期：2007-01-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is common in patients with many chronic diseases, but has not been well recognized in rheumatoid arthritis (RA). We investigated the prevalence of GERD symptoms in 278 outpatients with RA and their association with such clinical factors as age, sex, height, weight, body mass inde...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nampei A,Shi K,Ebina K,Tomita T,Sugamoto K,Yoshikawa H,Hirao M,Hashimoto J

更新日期：2013-03-01 00:00:00

abstract：:THE STUDY EVALUATED AND COMPARED THE DIFFERENCES OF GLUCOSE RESPONSES, INCREMENTAL AREA UNDER CURVE (IAUC), GLYCEMIC INDEX (GI) AND THE CLASSIFICATION OF GI VALUES BETWEEN MEASURED BY BIOCHEMICAL ANALYZER (FUJI AUTOMATIC BIOCHEMISTRY ANALYZER (FAA)) AND THREE GLUCOSE METERS: Accue Chek Advantage (AGM), BREEZE 2 (BGM),...

journal_title：Journal of clinical biochemistry and nutrition

authors： Lin MH,Wu MC,Lin J

更新日期：2010-07-01 00:00:00

abstract：:Intestinal ischemia/reperfusion injury is a severe disease associated with a high mortality. The mechanisms that cause ischemia/reperfusion injury are complex and many factors are involved in the injury formation process; however, the only available treatment is surgical intervention. Recent studies demonstrated that ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nadatani Y,Watanabe T,Shimada S,Otani K,Tanigawa T,Fujiwara Y

更新日期：2018-07-01 00:00:00

abstract：:Citrus bioflavonoids may offer some protection against the early stage of diabetes mellitus and the development of complications. We investigated the effect of hesperidin on blood glucose levels, hepatic glucose-regulating enzyme activities, serum insulin and adiponectin levels, serum and hepatic lipid levels, and par...

journal_title：Journal of clinical biochemistry and nutrition

authors： Akiyama S,Katsumata S,Suzuki K,Ishimi Y,Wu J,Uehara M

更新日期：2010-01-01 00:00:00

abstract：:Resistance to anti-fungal drugs has become the main cause for increasing incidence rate of Candida infections in pediatric intensive care units (PICU). Zinc supplementation has been shown to exhibit beneficial effects on many pediatric illnesses. This study aimed to investigate the efficacy of zinc supplementation on ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Xie J,Zhu L,Zhu T,Jian Y,Ding Y,Zhou M,Feng X

更新日期：2019-03-01 00:00:00

abstract：:Plant sterols are used as food additives to reduce intestinal cholesterol absorption. They also increase fecal neutral sterol (FNS) excretion irrespective of the absorption inhibition. Intestine-mediated reverse cholesterol transport, or trans-intestinal cholesterol efflux (TICE), provides the major part of the increa...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nakano T,Inoue I,Takenaka Y,Ikegami Y,Kotani N,Shimada A,Noda M,Murakoshi T

更新日期：2018-09-01 00:00:00

abstract：:The fatty acid composition of serum phospholipids were analyzed in 20 patients with alcoholic liver cirrhosis (11 with malnutrition and 9 with acceptable nutritional status); 25 healthy age and sex-matched adults were used as controls. Cirrhotic patients showed higher levels of palmitic acid and total saturated fatty ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Ristić-Medić D,Takić M,Vučić V,Kandić D,Kostić N,Glibetić M

更新日期：2013-07-01 00:00:00