Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial.

abstract：:Oxidative stress (OS) has been implicated as one of the major underlying mechanisms behind many acute and chronic diseases. However, the measurement of free radicals or their end products is complicated. Isoprostanes, derived from the non-enzymatic peroxidation of arachidonic acid are now considered to be reliable bio...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kaviarasan S,Muniandy S,Qvist R,Ismail IS

更新日期：2009-07-01 00:00:00

abstract：:We investigated the effects of treatment with antibodies against tumor necrosis factor (TNF)-α on energy metabolism, nutritional status, serum cytokine levels in patients with Crohn's disease (CD). Twelve patients were enrolled. Resting energy expenditure (REE) levels were measured by indirect calorimetry. Crohn's dis...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nishida N,Sasaki M,Kurihara M,Ichimaru S,Wakita M,Bamba S,Andoh A,Fujiyama Y,Amagai T

更新日期：2013-09-01 00:00:00

abstract：:Anti-peptic and anti-inflammatory actions of ecabet sodium might be beneficial in either improving gastritis or relieving dyspeptic symptoms. This study was designed to evaluate the clinical efficacy of ecabet sodium on dyspeptic symptoms and to elucidate the molecular mechanism attributable to symptom relief in patie...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yang Kim H,Hahm KB,Choi MG,Rew JS,Seol SY,Chun HJ,Lee OY,Hong WS

更新日期：2007-11-01 00:00:00

abstract：:Changes in l-arginine metabolism, including increased arginase levels and decreased nitric oxide production, are involved in the pathophysiology of asthma. In this study, using an intranasal mite-induced NC/Nga mouse model of asthma, we examined whether administration of l-arginine ameliorated airway hyperresponsivene...

journal_title：Journal of clinical biochemistry and nutrition

authors： Zhang R,Kubo M,Murakami I,Setiawan H,Takemoto K,Inoue K,Fujikura Y,Ogino K

更新日期：2015-05-01 00:00:00

abstract：:Neutrophil accumulation within epithelial crypts and in the intestinal mucosa directly correlates with clinical disease activity and epithelial injury in ulcerative colitis (UC). Current advances have defined the mechanisms by which neutrophils are activated or migrate across mucosal epithelia. A better understanding ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Naito Y,Takagi T,Yoshikawa T

更新日期：2007-07-01 00:00:00

abstract：:The present study was conducted in order to determine whether oxidative stress during aging involves dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis in association with the emergence of cognitive deficits. When young rats were subjected to oxidative stress in the form of hyperoxia, thiobarbituric acid rea...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kobayashi N,Machida T,Takahashi T,Takatsu H,Shinkai T,Abe K,Urano S

更新日期：2009-09-01 00:00:00

abstract：:Mammals have the biological clocks with approximately 24 h-rhythm. Energy metabolism including glucose metabolism is regulated by the biological clocks. Glucose metabolism is affected by not only meal volume and its energy but also meal timing. We have reported that cacao liquor procyanidin-rich extract (CLPr) amelior...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hironao KY,Ashida H,Yamashita Y

更新日期：2020-07-01 00:00:00

abstract：:Peyer's patches are nodules that play a central role in intestinal immunity. Few studies demonstrate the relationship between the number of Peyer's patches and intestinal polyps. Here we identify a statistically significant inverse correlation between the quantity of Peyer's patches and of the development of intestina...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fujimoto K,Fujii G,Sakurai H,Yoshitome H,Mutoh M,Wada M

更新日期：2015-01-01 00:00:00

abstract：:This study aimed to consider the significance of breast milk in preventing oxidative stress by comparing total antioxidant capacity (TAC) in breast milk and formula milk for premature infants, demonstrating the relationship between TAC in breast milk and postnatal age in days. We used the biological anti-oxidant poten...

journal_title：Journal of clinical biochemistry and nutrition

authors： Ezaki S,Ito T,Suzuki K,Tamura M

更新日期：2008-03-01 00:00:00

abstract：:Previously, we identified four metabolites of (-)-epicatechin in blood and urine: (-)-epicatechin-3'-O-glucuronide (E3'G), 4'-O-methyl-(-)-epicatechin-3'-O-glucuronide (4'ME3'G), (-)-epicatechin-7-O-glucuronide (E7G), and 3'-O-methyl-(-)-epicatechin-7-O-glucuronide (3'ME7G) (Natsume et al. Free Radical Biol. Med. 34, ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Natsume M,Osakabe N,Yasuda A,Osawa T,Terao J

更新日期：2008-01-01 00:00:00

abstract：:We investigated the effects of anticancer agents on peripheral blood mononuclear cells for the purpose of providing data to support new translational chemoimmunotherapy regimens. Peripheral-blood mononuclear cells were treated with one of four anticancer agents (5-fluorouracil, irinotecan, cisplatin, and gemcitabine) ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Sakai H,Kokura S,Ishikawa T,Tsuchiya R,Okajima M,Matsuyama T,Adachi S,Katada K,Kamada K,Uchiyama K,Handa O,Takagi T,Yagi N,Naito Y,Yoshikawa T

更新日期：2013-01-01 00:00:00

abstract：:Iron is an essential metallic microelement for life. However, iron overload is toxic. The liver serves an important role as a storehouse for iron in the body. About 20-25 mg of iron is required each day for hemoglobin synthesis. To maintain iron homeostasis, transferrin and transferrin receptors are primarily involved...

journal_title：Journal of clinical biochemistry and nutrition

authors： Takami T,Sakaida I

更新日期：2011-03-01 00:00:00

abstract：:Carnitine is a vitamin-like compound that plays important roles in fatty acid β-oxidation and the control of the mitochondrial coenzyme A/acetyl-CoA ratio. However, carnitine is not added to ordinary enteral nutrition or total parenteral nutrition. In this study, we determined the serum carnitine concentrations in sub...

journal_title：Journal of clinical biochemistry and nutrition

authors： Iwamoto J,Honda A,Miyamoto Y,Miyazaki T,Murakami M,Saito Y,Ikegami T,Miyamoto J,Matsuzaki Y

更新日期：2014-11-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is common in patients with many chronic diseases, but has not been well recognized in rheumatoid arthritis (RA). We investigated the prevalence of GERD symptoms in 278 outpatients with RA and their association with such clinical factors as age, sex, height, weight, body mass inde...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nampei A,Shi K,Ebina K,Tomita T,Sugamoto K,Yoshikawa H,Hirao M,Hashimoto J

更新日期：2013-03-01 00:00:00

abstract：:Imbalance between reactive oxygen species generation and antioxidant capacity induces a condition known as oxidative stress which is implicated in numerous pathological processes. In this study we evaluated whether natural zeolites chabazite/phillipsite/analcime may affect the levels of different antioxidant enzymes (...

journal_title：Journal of clinical biochemistry and nutrition

authors： Dogliotti G,Malavazos AE,Giacometti S,Solimene U,Fanelli M,Corsi MM,Dozio E

更新日期：2012-05-01 00:00:00

abstract：:It is accepted that pulmonary exposure of rodents to porcine pancreatic elastase (ELT) induces lesions that morphologically resemble human emphysema. Nonetheless, extensive analysis of this model has rarely been conducted. The present study was designed to extensively examine the effects of ELT on lung inflammation, c...

journal_title：Journal of clinical biochemistry and nutrition

authors： Inoue K,Koike E,Yanagisawa R,Takano H

更新日期：2010-03-01 00:00:00

abstract：:Although carbon monoxide derived from heme oxygenase has been reported to exert diverse biological actions in mammals, macromolecules responsible for its direct reception and functional outcomes of the gas binding remain largely unknown. Based on our previous results in vivo suggesting carbon monoxide serves as an inh...

journal_title：Journal of clinical biochemistry and nutrition

authors： Yamamoto T,Takano N,Ishiwata K,Suematsu M

更新日期：2011-01-01 00:00:00

abstract：:Although atopic dermatitis is known to be closely associated with food antigens, the actual changes in the gastrointestinal tract have not been clarified. The aim of this study was to investigate the macroscopic and histological features of the large intestine in patients with atopic dermatitis. We studied 15 outpatie...

journal_title：Journal of clinical biochemistry and nutrition

authors： Arisawa T,Arisawa S,Yokoi T,Kuroda M,Hirata I,Nakano H

更新日期：2007-01-01 00:00:00

abstract：:Antioxidant supplementations are commonly used as an ergogenic aid for physical exercise despite its limited evidence. The study aimed to investigate the effects of a polyphenol mixture and vitamins on exercise endurance capacity. Seventy regularly exercising male participants were randomly assigned to receive oligome...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kang SW,Hahn S,Kim JK,Yang SM,Park BJ,Chul Lee S

更新日期：2012-03-01 00:00:00

abstract：:Nephrotoxicity is defined as renal dysfunction that arises as result of exposure to external agents such as drugs and environmental chemicals. The present work was undertaken to carry out the phytochemical study and nephroprotective activity of methanolic extract of Casuarina equisetifolia leaves in gentamicin-induced...

journal_title：Journal of clinical biochemistry and nutrition

authors： El-Tantawy WH,Mohamed SA,Abd Al Haleem EN

更新日期：2013-11-01 00:00:00

abstract：:Intestinal ischemia/reperfusion injury is a severe disease associated with a high mortality. The mechanisms that cause ischemia/reperfusion injury are complex and many factors are involved in the injury formation process; however, the only available treatment is surgical intervention. Recent studies demonstrated that ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Nadatani Y,Watanabe T,Shimada S,Otani K,Tanigawa T,Fujiwara Y

更新日期：2018-07-01 00:00:00

abstract：:Colon cancer prevalence is high worldwide. O-GlcNAcylation has been associated with tumor growth in various tissues, including the colon; however, its link to carcinogenesis is not fully understood. We investigated the association of O-GlcNAcylation with colon carcinogenesis using a 1,2-dimethylhydrazine/dextran sodiu...

journal_title：Journal of clinical biochemistry and nutrition

authors： Hirata Y,Nakagawa T,Moriwaki K,Koubayashi E,Kakimoto K,Takeuchi T,Inoue T,Higuchi K,Asahi M

更新日期：2018-05-01 00:00:00

abstract：:Daily salt intake can be estimated by measuring sodium and creatinine concentrations in spot urine. Excessive salt intake is risk factor for gastric cancer. We examined the correlation between estimated salt intake from spot urine and risk of gastric cancer. This study included gastric cancer patients who underwent tr...

journal_title：Journal of clinical biochemistry and nutrition

authors： Goto A,Nishikawa J,Ito S,Hideura E,Shirasawa T,Hamabe K,Hashimoto S,Okamoto T,Yanai H,Sakaida I

更新日期：2020-01-01 00:00:00

abstract：:The aim of the study was to evaluate the anti-obesity effects of two types of meju in diet induced obese C57BL/6J mice. Animals were randomly divided into 4 dietary group (n = 10); normal diet, high fat diet with 30% soybean, high fat diet with 30% traditional meju, high fat diet with 30% standardized meju. After 16 w...

journal_title：Journal of clinical biochemistry and nutrition

authors： Bae CR,Kwon DY,Cha YS

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to evaluate the influence of sex on serum paraoxonase-1 (PON1) activities and on its relationship with cardiovascular disease risk factors such as overall and central obesity. Arylesterase and lactonase activities of PON1 were assessed in 374 women and 92 men. Both arylesterase and lactonase ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Trentini A,Bellini T,Bonaccorsi G,Cavicchio C,Hanau S,Passaro A,Cervellati C

更新日期：2019-05-01 00:00:00

abstract：:Consumption of olives (Olea europaea L.) is associated with a low incidence of inflammation-related diseases. Olive fruit is rich in bioactive pentacyclic triterpenoids, mainly maslinic acid. This study, a randomized, double-blind, and placebo-controlled trial, examined the effects of an orally administered maslinic a...

journal_title：Journal of clinical biochemistry and nutrition

authors： Fukumitsu S,Villareal MO,Aida K,Hino A,Hori N,Isoda H,Naito Y

更新日期：2016-11-01 00:00:00

abstract：:The therapeutic effects of non-thermal plasma are expected in the medical fields, including hemostasis, vascularization, prevention of organ adhesion, and cell proliferation. Cancer is an internal enemy arising from normal tissue in the body. The prognosis of metastatic and recurrent cancers is still poor despite adva...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kajiyama H,Utsumi F,Nakamura K,Tanaka H,Toyokuni S,Hori M,Kikkawa F

更新日期：2017-01-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays a crucial role in cancer metastasis. In this study, we evaluated the effect of heat treatment on tumor growth factor-β1 (TGF-β1)-induced EMT in pancreatic cancer cells and tried to ascertain the mechanism related to any observed effects. Human pancreatic cancer cell lines ...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kimura-Tsuchiya R,Ishikawa T,Kokura S,Mizushima K,Adachi S,Okajima M,Matsuyama T,Okayama T,Sakamoto N,Katada K,Kamada K,Uchiyama K,Handa O,Takagi T,Yagi N,Naito Y,Itoh Y

更新日期：2014-07-01 00:00:00

abstract：:Although some studies have indicated a correlation between Helicobacter pylori infection and the risk of colorectal neoplasms, these findings have not been consistent and are controversial. This case-control study aimed to investigate the association between endoscopic gastric mucosal atrophy and colorectal polyp occu...

journal_title：Journal of clinical biochemistry and nutrition

authors： Kawahara Y,Kodama M,Mizukami K,Saito T,Hirashita Y,Sonoda A,Fukuda K,Matsunari O,Okamoto K,Ogawa R,Okimoto T,Murakami K

更新日期：2019-09-01 00:00:00

abstract：:Ubiquinol-10 (QH(2)), the reduced form of Coenzyme Q(10) (CoQ(10)) serves as a potent antioxidant of lipid membranes. Because many antioxidants reveal potent anti-inflammatory effects, the influence of QH(2) on lipopolysaccharide (LPS)-induced pro-inflammatory cytokines and chemokines were determined in the human mono...

journal_title：Journal of clinical biochemistry and nutrition

authors： Schmelzer C,Lorenz G,Rimbach G,Döring F

更新日期：2009-01-01 00:00:00