Transient cold nodule of the thyroid due to localized postpartum thyroiditis.


:A 27-year-old woman with no previous personal or family history of thyroid disease was referred to us for the evaluation of thyroid nodule, five months postpartum. Thyroid scintigraphy demonstrated a left cold nodule. Fine needle aspiration cytology of the nodule showed a mixture of colloid, follicular cells and lymphocytes, suggesting lymphocytic thyroiditis. Thyroid function tests were normal and thyroid autoantibodies were negative. After two months the thyroid nodule was not palpated and thyroid scintigraphy returned to normal. Thyroid function tests remained normal twelve months after delivery. These findings suggest that postpartum thyroiditis may present as a localized transient form and should be considered in the differential diagnosis of painless solitary nodule that appears postpartum.


Eur J Endocrinol


Luboshitzky R,Qupti G,Ishai A,Dharan M




Has Abstract


1998-05-01 00:00:00












  • Anthropometric, computed tomography and fat cell data in an obese population: relationship with insulin, leptin, tumor necrosis factor-alpha, sex hormone-binding globulin and sex hormones.

    abstract:OBJECTIVE:To correlate anthropometric, computed tomography and fat cell data from abdominal regions with the levels of serum insulin, C-peptide, leptin, tumor necrosis factor-alpha (TNF-alpha), testosterone, 17beta-estradiol, androstenedione, dehydroepiandrosterone sulphate (DHEA-S) and sex hormone-binding globulin (SH...

    journal_title:European journal of endocrinology

    pub_type: 临床试验,杂志文章


    authors: Garaulet M,Pérex-Llamas F,Fuente T,Zamora S,Tebar FJ

    更新日期:2000-11-01 00:00:00

  • Serum sex steroids measured in middle-aged European and African-Caribbean men by gas chromatography-mass spectrometry.

    abstract:BACKGROUND:Differences in circulating steroid hormone levels have been hypothesized to explain ethnic differences in steroid-related diseases. The aim of this study was to determine the serum levels of a wide panel of steroid hormones, both androgens and estrogens, in healthy middle-aged African-Caribbean and European ...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,随机对照试验


    authors: Giton F,Fiet J,Cornu JN,Cussenot O,Bélanger A,Urien S,Oliva A,Blanchet P,Multigner L

    更新日期:2011-12-01 00:00:00

  • Pancreatic alpha-cell mass across adult human lifespan.

    abstract:Aim:To establish pancreatic alpha-cell mass in lean, non-diabetic humans over the adult lifespan, performed as a follow-up study to beta-cell mass across the adult human lifespan. Methods:We examined human pancreatic autopsy tissue from 66 lean, non-diabetic individuals aged from 30 to 102 years, grouped into deciles:...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Moin ASM,Cory M,Gurlo T,Saisho Y,Rizza RA,Butler PC,Butler AE

    更新日期:2020-02-01 00:00:00

  • Soluble α-klotho: a novel serum biomarker for the activity of GH-producing pituitary adenomas.

    abstract:OBJECTIVE:Klotho is a lifespan-influencing gene expressed mainly in the kidneys. Soluble α-Klotho (αKL) is released into the circulation. In this study, we present baseline αKL serum levels of patients with acromegaly compared with controls with other pituitary adenomas and assess changes following transsphenoidal surg...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Neidert MC,Sze L,Zwimpfer C,Sarnthein J,Seifert B,Frei K,Leske H,Rushing EJ,Schmid C,Bernays RL

    更新日期:2013-03-15 00:00:00

  • Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation.

    abstract:BACKGROUND:Nateglinide restores early-phase insulin secretion to feeding and reduces postprandial hyperglycaemia in type 2 diabetes. This study evaluated the effects of nateglinide on dipeptidyl peptidase-IV (DPP-IV) activity and glucose-dependent insulinotropic polypeptide (GIP) degradation. Research design and method...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,随机对照试验


    authors: McKillop AM,Duffy NA,Lindsay JR,Green BD,Patterson S,O'Harte FP,Bell PM,Flatt PR

    更新日期:2009-12-01 00:00:00

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    abstract::Phaeochromocytoma is a rare, usually benign, tumour predominantly managed by endocrinologists. Over the last decade, major advances have been made in understanding the molecular genetic basis of adrenal and extra-adrenal phaeochromocytoma (also referred to as adrenal phaeochromocytoma (aPCA) and extra-adrenal function...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,评审


    authors: Jafri M,Maher ER

    更新日期:2012-02-01 00:00:00

  • Hypochondroplasia and Acanthosis nigricans: a new syndrome due to the p.Lys650Thr mutation in the fibroblast growth factor receptor 3 gene?

    abstract:BACKGROUND:Hypochondroplasia (HCH) is a skeletal dysplasia inherited in an autosomal dominant manner due, in most cases, to mutations in the fibroblast growth factor receptor 3 (FGFR3). Acanthosis nigricans (AN) is a velvety and papillomatous pigmented hyperkeratosis of the skin, which has been recognized in some genet...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Castro-Feijóo L,Loidi L,Vidal A,Parajes S,Rosón E,Alvarez A,Cabanas P,Barreiro J,Alonso A,Domínguez F,Pombo M

    更新日期:2008-09-01 00:00:00

  • Increased expression of tumor necrosis factor-alpha and decreased expression of thyroglobulin and thyroid peroxidase mRNA levels in the thyroids of iodide-treated BB/Wor rats.

    abstract::Several lines of evidence suggest that tumor necrosis factor-alpha (TNFalpha) may contribute to the pathogenesis of autoimmune thyroid disease. It is not known, however, whether increased thyroidal TNFalpha levels are associated with changes in thyroid function. The purpose of the present study was to utilize in situ ...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Mori K,Mori M,Stone S,Braverman LE,DeVito WJ

    更新日期:1998-11-01 00:00:00

  • Bone resorption in healthy and osteoporotic postmenopausal women: comparison markers for serum carboxy-terminal telopeptide of type I collagen and urinary pyridinium cross-links.

    abstract::We compared two highly specific markers for bone resorption-pyridinium cross-links (pyridinoline (PYR) and deoxypyridinoline (DPR)) in urine and carboxy-terminal telopeptide of type I collagen (ICTP) in serum-in 63 healthy postmenopausal women and 63 women with osteoporosis characterized by more bone resorption than b...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Välimäki MJ,Tähtelä R,Jones JD,Peterson JM,Riggs BL

    更新日期:1994-09-01 00:00:00

  • Identification and characterization of a corticotrophin-releasing hormone receptor in human placenta.

    abstract::Corticotrophin-releasing hormone (CRH) causes vasodilatation in the human fetal-placental circulation and has paracrine actions in placental tissue, suggesting that CRH receptors may be present in the human placenta. We have now identified and characterized placental CRH binding sites and compared them to those descri...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Clifton VL,Owens PC,Robinson PJ,Smith R

    更新日期:1995-11-01 00:00:00

  • Insulin-like growth factors I and II in healthy women with and without established osteoporosis.

    abstract::We measured serum concentrations of insulin-like growth factors I and II (IGF-I and IGF-II) by radioimmunoassay in 107 healthy women aged 28-78 years and in 116 women with established osteoporosis. The women with established osteoporosis were randomized to a 1-year double-blind, placebo-controlled treatment with conti...

    journal_title:European journal of endocrinology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Ravn P,Overgaard K,Spencer EM,Christiansen C

    更新日期:1995-03-01 00:00:00

  • Relationship between serum adiponectin concentration, pulse wave velocity and nonalcoholic fatty liver disease.

    abstract:OBJECTIVES:We aimed to investigate the relationship between nonalcoholic fatty liver disease (NAFLD), serum adiponectin concentration and brachial-ankle pulse wave velocity (baPWV) as a risk marker for atherosclerosis. METHODS:A total of 213 nonalcoholic subjects (67 males, 146 females) participated in this study. Div...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Kim SG,Kim HY,Seo JA,Lee KW,Oh JH,Kim NH,Choi KM,Baik SH,Choi DS

    更新日期:2005-02-01 00:00:00

  • Hyperprolactinaemia is associated with a higher prevalence of pituitary-adrenal dysfunction in non-functioning pituitary macroadenoma.

    abstract::In non-functioning pituitary macroadenoma (NFMA), hyperprolactinaemia (hyperPRL) is considered to be a sign of hypothalamic-pituitary dysregulation, but it is unknown whether hyperPRL is associated with an increased frequency of pituitary hormone deficiencies. Forty consecutive patients with histology-proven NFMA were...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Tjeerdsma G,Sluiter WJ,Hew JM,Molenaar WM,de Lange WE,Dullaart RP

    更新日期:1996-09-01 00:00:00

  • The genetic characteristics of congenital hypothyroidism in China by comprehensive screening of 21 candidate genes.

    abstract:OBJECTIVE:Congenital hypothyroidism (CH), the most common neonatal metabolic disorder, is characterized by impaired neurodevelopment. Although several candidate genes have been associated with CH, comprehensive screening of causative genes has been limited. DESIGN AND METHODS:One hundred ten patients with primary CH w...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Sun F,Zhang JX,Yang CY,Gao GQ,Zhu WB,Han B,Zhang LL,Wan YY,Ye XP,Ma YR,Zhang MM,Yang L,Zhang QY,Liu W,Guo CC,Chen G,Zhao SX,Song KY,Song HD

    更新日期:2018-06-01 00:00:00

  • Screening for mutations in 17β-hydroxysteroid dehydrogenase and androgen receptor in women presenting with partially virilised 46,XY disorders of sex development.

    abstract:CONTEXT AND OBJECTIVE:The precise diagnosis of partially virilised women with 46,XY disorders of sex development (DSD) is often obscure. In practice, this group often comes under the poorly defined, clinically based label of partial androgen insensitivity syndrome (PAIS). In a previous study, we found that 5α-reductase...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Phelan N,Williams EL,Cardamone S,Lee M,Creighton SM,Rumsby G,Conway GS

    更新日期:2015-06-01 00:00:00

  • Absence of regular pulsatile LH secretion during pre- and post-implantation periods in sheep.

    abstract::Two experiments were conducted to determine the patterns of LH secretion and to evaluate the LH responses to pulsatile administration of GnRH during early pregnancy in ewes. In experiment 1, pregnant ewes (n=16) were used to determine the concentration of LH in plasma of jugular blood samples collected every 15 min fo...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Al-Gubory KH

    更新日期:1999-11-01 00:00:00

  • Health-related quality of life, anxiety and depression in thyroid cancer patients under short-term hypothyroidism and TSH-suppressive levothyroxine treatment.

    abstract:OBJECTIVE:Very few previous studies have compared the degree of health-related quality of life (HRQL), depression and anxiety of differentiated thyroid cancer patients (DTC) under short-term hypothyroid-ism and levothyroxine treatment. METHODS:Using patient-completed instruments, we examined the frequency of physical ...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Tagay S,Herpertz S,Langkafel M,Erim Y,Freudenberg L,Schöpper N,Bockisch A,Senf W,Görges R

    更新日期:2005-12-01 00:00:00

  • Trans-sphenoidal surgery for microprolactinoma: an acceptable alternative to dopamine agonists?

    abstract:AIMS:Reported cure rates following trans-sphenoidal surgery for microprolactinoma are variable and recurrence rates in some series are high. We wished to examine the cure rate of trans-sphenoidal surgery for microprolactinoma, and to assess the long-term complications and recurrence rate. DESIGN:A retrospective review...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Turner HE,Adams CB,Wass JA

    更新日期:1999-01-01 00:00:00

  • IGF-I increases the recruitment of GLUT4 and GLUT3 glucose transporters on cell surface in hyperthyroidism.

    abstract:OBJECTIVE:In hyperthyroidism, tissue glucose disposal is increased to adapt to high energy demand. Our aim was to examine the regulation of glucose transporter (GLUT) isoforms by IGF-I in monocytes from patients with hyperthyroidism. DESIGN AND METHODS:Blood (20 ml) was drawn from 21 healthy and 10 hyperthyroid subjec...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Dimitriadis G,Maratou E,Boutati E,Kollias A,Tsegka K,Alevizaki M,Peppa M,Raptis SA,Hadjidakis DJ

    更新日期:2008-03-01 00:00:00

  • TSH-suppressive doses of levothyroxine are required to achieve preoperative native serum triiodothyronine levels in patients who have undergone total thyroidectomy.

    abstract:OBJECTIVE:Thyroidal production of triiodothyronine (T(3)) is absent in patients who have undergone total thyroidectomy. Therefore, relative T(3) deficiency may occur during postoperative levothyroxine (L-T(4)) therapy. The objective of this study was to evaluate how the individual serum T(3) level changes between preop...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Ito M,Miyauchi A,Morita S,Kudo T,Nishihara E,Kihara M,Takamura Y,Ito Y,Kobayashi K,Miya A,Kubota S,Amino N

    更新日期:2012-09-01 00:00:00

  • Growth hormone replacement does not increase serum prostate-specific antigen in hypopituitary men over 50 years.

    abstract:OBJECTIVE:Epidemiological studies have shown an increased risk for prostate carcinoma in men with serum IGF-I in the upper part of the age-related reference range. Recombinant human GH (rhGH) is widely used in patients with GH deficiency, usually raising the serum IGF-I levels into the normal range: safety surveillance...

    journal_title:European journal of endocrinology

    pub_type: 临床试验,杂志文章


    authors: le Roux CW,Jenkins PJ,Chew SL,Camacho-Hübner C,Grossman AB,Besser GM,Monson JP

    更新日期:2002-07-01 00:00:00

  • The use of 18-fluoro-dihydroxyphenylalanine and 18-fluorodeoxyglucose positron emission tomography scanning in the assessment of metaiodobenzylguanidine-negative phaeochromocytoma.

    abstract::123I-metaiodobenzylguanidine (123I-MIBG) scintigraphy scanning is commonly used in the imaging of phaeochromocytoma (and paraganglioma) to confirm the site of disease and whether any spread has occurred. However, 123I-MIBG imaging is negative in 15% of cases of benign phaeochromocytoma and around 50% of cases of malig...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Mackenzie IS,Gurnell M,Balan KK,Simpson H,Chatterjee K,Brown MJ

    更新日期:2007-10-01 00:00:00

  • MANAGEMENT OF ENDOCRINE DISEASE: Personalized medicine in the treatment of acromegaly.

    abstract::Acromegaly is associated with high morbidity and elevated mortality when not adequately treated. Surgery is the first-line treatment for most patients as it is the only one that can lead to immediate cure. In patients who are not cured by surgery, treatment is currently based on a trial-and-error approach. First-gener...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章,评审


    authors: Kasuki L,Wildemberg LE,Gadelha MR

    更新日期:2018-03-01 00:00:00

  • MRI T2 signal intensity and tumor response in patients with GH-secreting pituitary macroadenoma: PRIMARYS post-hoc analysis.

    abstract::Objective Pituitary adenoma MRI T2 signal intensity associates with tumor characteristics including responsiveness to somatostatin analogs (SSAs). These analyses determined whether baseline T2 signal intensity predicts response to primary medical treatment with long-acting SSA. Design Post-hoc analyses of the prospect...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Bonneville F,Rivière LD,Petersenn S,Bevan J,Houchard A,Sert C,Caron PJ,PRIMARYS Study group.

    更新日期:2018-12-01 00:00:00

  • Should parafibromin staining replace HRTP2 gene analysis as an additional tool for histologic diagnosis of parathyroid carcinoma?

    abstract:OBJECTIVE:HRPT2 gene mutations are associated with parathyroid carcinomas, and absence of parafibromin immunoreactivity has been suggested as a diagnostic marker of malignancy. The aim of our study was to extend parafibromin studies in a series of benign and malignant parathyroid tumors and cross-validate the results o...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Cetani F,Ambrogini E,Viacava P,Pardi E,Fanelli G,Naccarato AG,Borsari S,Lemmi M,Berti P,Miccoli P,Pinchera A,Marcocci C

    更新日期:2007-05-01 00:00:00


    abstract::Design Hypercortisolism during pregnancy is a risk factor for prematurity. Long-term exposure to hypercortisolism may lead to permanent comorbidities, such as hypertension or diabetes, even after remission. Our aim was to determine whether women with a history of Cushing's disease (and being eu-, hypo- or hypercortiso...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Hochman C,Cristante J,Geslot A,Salenave S,Sonnet E,Briet C,Bachelot A,Chevalier N,Gilly O,Brue T,Hadjadj S,Kerlan V,Chanson P,Vezzosi D,Chabre O,Drui DD,Castinetti FF

    更新日期:2021-01-01 00:00:00

  • Effectiveness of eplerenone or spironolactone treatment in preserving renal function in primary aldosteronism.

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    journal_title:European journal of endocrinology

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Fourkiotis V,Vonend O,Diederich S,Fischer E,Lang K,Endres S,Beuschlein F,Willenberg HS,Rump LC,Allolio B,Reincke M,Quinkler M,Mephisto Study Group.

    更新日期:2012-12-10 00:00:00

  • Protective effect of dehydroepiandrosterone against lipid peroxidation in a human liver cell line.

    abstract:OBJECTIVE:Dehydroepiandrosterone (DHEA) is a widely studied steroid hormone with multi-functional properties. Reports suggest that some of the many activities of DHEA are due to its protective effect against lipid peroxidation. Nevertheless, the antioxidant properties of DHEA are still the subject of debate. The aim wa...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Gallo M,Aragno M,Gatto V,Tamagno E,Brignardello E,Manti R,Danni O,Boccuzzi G

    更新日期:1999-07-01 00:00:00

  • Intracellular depletion of insulin: a comparative study with palmitate, oleate and elaidate in INS-1 cells.

    abstract:OBJECTIVE:Free fatty acids (FFAs) deplete the intracellular insulin stores of pancreatic beta-cells. It has been suggested that this results from a lipotoxic dysregulation of both insulin secretion and insulin synthesis. In the present study, this hypothesis was tested within a 12-h time-course by directly relating the...

    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: Bollheimer LC,Kemptner DM,Kagerbauer SM,Kestler TM,Wrede CE,Buettner R

    更新日期:2003-04-01 00:00:00

  • Thyroid morphology in lethal non-thyroidal illness: a post-mortem study.

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    journal_title:European journal of endocrinology

    pub_type: 杂志文章


    authors: De Jongh FE,Jöbsis AC,Elte JW

    更新日期:2001-03-01 00:00:00