Anthropomorphic 1H MRS head phantom.

abstract：PURPOSE:The purpose of this study was to investigate the potential of MR-guided pulsed focused ultrasound (pFUS) for the enhancement of drug uptake in prostate tumors in vivo using doxorubicin (Dox). METHODS:An antitumor drug Dox, an orthotopic animal prostate tumor model using human prostate cancer, LNCaP cell line, ...

journal_title：Medical physics

authors： Chen X,Cvetkovic D,Ma CM,Chen L

更新日期：2012-05-01 00:00:00

abstract：:Three types of iterative algorithms, algebraic inverse treatment planning (AITP), simultaneous iterative inverse treatment planning (SIITP), and iterative least-square inverse treatment planning (ILSITP), differentiated according to their updating sequences, were generalized to three dimension with true beam geometry ...

journal_title：Medical physics

authors： Xing L,Hamilton RJ,Spelbring D,Pelizzari CA,Chen GT,Boyer AL

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:Transcranial focused ultrasound is an emerging therapeutic modality that can be used to perform noninvasive neurosurgical procedures. The current clinical transcranial phased array operates at 650 kHz, however the development of a higher frequency array would enable more precision, while reducing the risk of st...

journal_title：Medical physics

authors： Pajek D,Hynynen K

更新日期：2013-12-01 00:00:00

abstract：:Subsecond single-slice, multi-slice or cone-beam spiral computed tomography (SSCT, MSCT, CBCT) offer great potential for improving heart imaging. Together with the newly developed phase-correlated cardiac reconstruction algorithms 180 degrees MCD and 180 degrees MCI [Med. Phys. 27, 1881-1902 (2000)] or related algorit...

journal_title：Medical physics

authors： Kachelriess M,Sennst DA,Maxlmoser W,Kalender WA

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:The GammaPod is a novel dedicated prone breast stereotactic radiosurgery (SRS) device recently developed at the University of Maryland Medical Center. This device utilizes multiple rotating Co-60 sources to create highly conformal dose distributions for breast treatments, including boosts, partial breast irradi...

journal_title：Medical physics

authors： Becker SJ,Culberson WS,Poirier Y,Mutaf Y,Niu Y,Nichols EM,Yi B

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:The purpose of this study was to detect and analyze anomalies between a large number of computed tomography (CT) scanners, tracked over time, utilized to collect human pulmonary CT data for a national multicenter study: chronic obstructive pulmonary disease genetic epidemiology study (COPDGene). METHODS:A cust...

journal_title：Medical physics

authors： Sieren JP,Newell JD,Judy PF,Lynch DA,Chan KS,Guo J,Hoffman EA

更新日期：2012-09-01 00:00:00

abstract：:Amorphous selenium (a-Se) based real-time flat-panel imagers (FPIs) are finding their way into the digital radiology department because they offer the practical advantages of digital x-ray imaging combined with an image quality that equals or outperforms that of conventional systems. The temporal imaging characteristi...

journal_title：Medical physics

authors： Rau AW,Bakueva L,Rowlands JA

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:To investigate the difference of MR percent breast density measured from fat-suppressed versus nonfat-suppressed imaging sequences. METHODS:Breast magnetic resonance imaging (MRI) with and without fat suppression was acquired from 38 subjects. Breasts were divided into subgroups of different morphological patt...

journal_title：Medical physics

authors： Chang DH,Chen JH,Lin M,Bahri S,Yu HJ,Mehta RS,Nie K,Hsiang DJ,Nalcioglu O,Su MY

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Currently, in clinical practice of intensity-modulated proton therapy (IMPT), the influence of the minimum monitor unit (MU) constraint is taken into account through postprocessing after the optimization is completed. This may degrade the plan quality and plan robustness. This study aims to mitigate the impact ...

journal_title：Medical physics

authors： Shan J,An Y,Bues M,Schild SE,Liu W

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:As hypoxic cells are more resistant to photon radiation, it is desirable to obtain information about the oxygen distribution in tumors prior to the radiation treatment. Noninvasive techniques are currently not able to provide reliable oxygenation maps with sufficient spatial resolution; therefore mathematical m...

journal_title：Medical physics

authors： Espinoza I,Peschke P,Karger CP

更新日期：2013-08-01 00:00:00

abstract：:A method for the in vivo determination of the isocenter dose, Diso, and mid-plane dose, Dm, using the transmitted signal St measured by 25 central pixels of an aSi-based EPID is here reported. The method has been applied to check the conformal radiotherapy of pelvic tumors and supplies accurate in vivo dosimetry avoid...

journal_title：Medical physics

authors： Piermattei A,Fidanzio A,Stimato G,Azario L,Grimaldi L,D'Onofrio G,Cilla S,Balducci M,Gambacorta MA,Di Napoli N,Cellini N

更新日期：2006-11-01 00:00:00

abstract：:Breast-conserving surgery combined with subsequent radiation therapy is a standard procedure in breast cancer treatment. The disadvantage of whole-breast beam irradiation is that it requires 20-25 treatment days, which is inconvenient for patients with limited mobility or who reside far from the treatment center. Howe...

journal_title：Medical physics

authors： De Jean P,Beaulieu L,Fenster A

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:The authors describe the integration of optical imaging with a targeted small animal irradiator device, focusing on design, instrumentation, 2D to 3D image registration, 2D targeting, and the accuracy of recovering and mapping the optical signal to a 3D surface generated from the cone-beam computed tomography (...

journal_title：Medical physics

authors： Weersink RA,Ansell S,Wang A,Wilson G,Shah D,Lindsay PE,Jaffray DA

更新日期：2014-10-01 00:00:00

abstract：PURPOSE:To formulate convex planning objectives of treatment plan multicriteria optimization with explicit relationships to the dose-volume histogram (DVH) statistics used in plan quality evaluation. METHODS:Conventional planning objectives are designed to minimize the violation of DVH statistics thresholds using pena...

journal_title：Medical physics

authors： Engberg L,Forsgren A,Eriksson K,Hårdemark B

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:Planning for the delivery of intensity-modulated radiation therapy (IMRT) to a moving target, referred to as four-dimensional (4D) IMRT planning, is a crucial step for achieving the treatment objectives for sites that move during treatment delivery. The authors proposed a simplistic method that accounts for bot...

journal_title：Medical physics

authors： Gui M,Feng Y,Yi B,Dhople AA,Yu C

更新日期：2010-05-01 00:00:00

abstract：:Lag in fluoroscopic systems introduces a frame-averaging effect that reduces measurements of image noise and incorrectly inflates measurements of the detective quantum efficiency (DQE). A correction can be implemented based on measurements of the temporal modulation transfer function (MTF). We introduce a method of me...

journal_title：Medical physics

authors： Friedman SN,Cunningham IA

更新日期：2008-06-01 00:00:00

abstract：:An important point to consider in a brachytherapy dosimetry study is the phantom size involved in calculations or experimental measurements. As pointed out by Williamson [Med. Phys. 18, 776-786 (1991)] this topic has a relevant influence on final dosimetric results. Presently, one-dimensional (1-D) algorithms and newl...

journal_title：Medical physics

authors： Pérez-Calatayud J,Granero D,Ballester F

更新日期：2004-07-01 00:00:00

abstract：PURPOSE:Two ultra-high-resolution (UHR) computed tomography (CT) scanners are clinically available. One is achieved by a CT system with a 0.25 mm × 160 row detector (Detector-UHR), whereas the other is with a 0.6 mm × 32 row detector with in-plane comb filtering in a dual source CT (Comb-UHR). We compared radiation dos...

journal_title：Medical physics

authors： Kawashima H,Ichikawa K,Takata T,Nagata H,Hoshika M,Akagi N

更新日期：2020-02-01 00:00:00

abstract：:Tissue absorbed dose (D) is a computed result for internal emitters. For fixed geometries, D is calculated by a matrix (S) multiplication of the integrated activity vector (Ã). The last quantity is usually measured by nuclear imaging of activity in various source organs and performing a temporal integration. Ã is the ...

journal_title：Medical physics

authors： Williams L

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:In the practice code of dosimetry, humidity effect is assumed to be constant as far as the measurements are performed in the relative humidity (RH) range of (20-80)%; thus, the humidity effect can be ignored with a dose uncertainty of 0.15%. This assumption is based on the previous experimental results by Niate...

journal_title：Medical physics

authors： Sato Y,Shimizu M,Morishita Y,Sato M,Hoshina M

更新日期：2019-09-01 00:00:00

abstract：:A simple modification is presented for two commercially available hyperthermia applicators which dramatically improves the regulation and dynamic control of the temperature at the bolus/tissue interface. This alteration requires the addition of a variable speed pump, bubble trap, simple heat exchanger, and a few minor...

journal_title：Medical physics

authors： Diederich CJ,Stauffer PR,Bozzo D

更新日期：1994-09-01 00:00:00

abstract：PURPOSE:To objectively characterize the performance of the gemstone spectral imaging (GSI) mode of GE CT750 HD scanner from a user's perspective. METHODS:A regular scan protocol that approximates the adult abdomen scan protocol frequently used in the authors' institute was selected as the baseline, and a GSI protocol ...

journal_title：Medical physics

authors： Zhang D,Li X,Liu B

更新日期：2011-03-01 00:00:00

abstract：:We describe the use of a graphical mathematical spreadsheet programming environment which can be used to simulate the acquisition and reconstruction processes of an x-ray computed tomography (CT) machine. The simulation is used to study the effect of photon counting statistics on the noise in the reconstructed image. ...

journal_title：Medical physics

authors： Harpen MD

更新日期：1999-08-01 00:00:00

abstract：:To account for clinical divergent and polychromatic photon beams, we have developed kernel tilting and kernel hardening correction methods for convolution dose calculation algorithms. The new correction methods were validated by Monte Carlo simulation. The accuracy and computation time of the our kernel tilting and ke...

journal_title：Medical physics

authors： Liu HH,Mackie TR,McCullough EC

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility of using an objective computer-aided system to assess bladder cancer stage in CT Urography (CTU). MATERIALS AND METHODS:A dataset consisting of 84 bladder cancer lesions from 76 CTU cases was used to develop the computerized system for bladder cancer staging based on machine learnin...

journal_title：Medical physics

authors： Garapati SS,Hadjiiski L,Cha KH,Chan HP,Caoili EM,Cohan RH,Weizer A,Alva A,Paramagul C,Wei J,Zhou C

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:In a recent paper by Bouchard et al. [Med. Phys. 36(10), 4654-4663 (2009)], a theoretical model of quality correction factors for idealistic so-called plan-class specific reference (PCSR) fields was proposed. The reasoning was founded on the definition of PCSR fields made earlier by Alfonso et al. [Med. Phys. 3...

journal_title：Medical physics

authors： Bouchard H,Seuntjens J,Palmans H

更新日期：2012-03-01 00:00:00

abstract：:Intravascular brachytherapy requires that the dose be specified within millimeters of the source. High dose gradients near brachytherapy sources require that the source-detector distance be accurately known for dosimetry purposes. Solid phantoms can be designed to accommodate these stringent requirements. This study r...

journal_title：Medical physics

authors： Buckley LA,Thomadsen BR,DeWerd LA

更新日期：2001-06-01 00:00:00

abstract：PURPOSE:The response of human cells to applied electrical signals depends on the cellular health status, because it is influenced by the composition and structure of the main cellular components. Therefore, electrical impedance-based techniques can be considered as sensitive tools to investigate healthy or disease stat...

journal_title：Medical physics

authors： Ambrico M,Lasalvia M,Ligonzo T,Ambrico PF,Perna G,Capozzi V

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:A novel 3D printing method has been developed, which employs human CT images to construct patient specific phantoms by controlling the filament extrusion rate. METHODS:An in-house software was developed comprising pixel-by-pixel (PbP) reading of the Hounsfield Units (HU) values in the original patient DICOM im...

journal_title：Medical physics

authors： Okkalidis N

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:To determine the accuracy of VMAT treatment planning and delivery for patients undergoing radiotherapy in the head and neck. METHOD AND MATERIALS:A dosimetric study of a typical head and neck treatment plan has been carried out using Chamber, film and TLD's placed inside an anthropomorphic phantom. Lateral and...

journal_title：Medical physics

authors： Aldaais E,Tedeschi D,Gebreamlak W,Shieder T,Alkhatib H

更新日期：2012-06-01 00:00:00