Utilization of DNA-protein cross-links as a biomarker of chromium exposure.

abstract：BACKGROUND:Persistent organic pollutants (POPs) are developmental toxicants, but the impact of both maternal and paternal exposures on offspring birth size is largely unexplored. OBJECTIVE:We examined associations between maternal and paternal serum concentrations of 63 POPs, comprising five major classes of pollutant...

journal_title：Environmental health perspectives

authors： Robledo CA,Yeung E,Mendola P,Sundaram R,Maisog J,Sweeney AM,Barr DB,Louis GM

更新日期：2015-01-01 00:00:00

abstract：:This article presents discussion of the assessment of the exposure of children to fungi, substances derived from fungi, and the environmental conditions that may lead to exposure. The principles driving investigations of fungal contamination and subsequent exposure are presented as well as guidelines for conducting th...

journal_title：Environmental health perspectives

authors： Dillon HK,Miller JD,Sorenson WG,Douwes J,Jacobs RR

更新日期：1999-06-01 00:00:00

abstract：:A brief overview is given of the sources, characteristics, and toxic constituents of municipal solid wastes. Several methods are presented for handling, treating, and disposal of solid wastes. Monitoring the landfill site is necessary; there has been a trend to recognize that municipal solid wastes may be hazardous an...

journal_title：Environmental health perspectives

authors： Stone R

更新日期：1978-12-01 00:00:00

abstract：:Flavone and isoflavone phytoestrogens are plant chemicals and are known to be competitive inhibitors of cytochrome P450 aromatase with respect to the androgen substrate. Aromatase is the enzyme that converts androgen to estrogen; therefore, these plant chemicals are thought to be capable of modifying the estrogen leve...

journal_title：Environmental health perspectives

authors： Kao YC,Zhou C,Sherman M,Laughton CA,Chen S

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Agricultural use of antimicrobials in subtherapeutic concentrations is increasing in response to the rising demand for food animal products worldwide. In India, the use of antimicrobials in food animal production is unregulated. Research suggests that many clinically important antimicrobials are used indiscr...

journal_title：Environmental health perspectives

authors： Brower CH,Mandal S,Hayer S,Sran M,Zehra A,Patel SJ,Kaur R,Chatterjee L,Mishra S,Das BR,Singh P,Singh R,Gill JPS,Laxminarayan R

更新日期：2017-07-20 00:00:00

abstract：:In recent years, exposure of man to increasing amounts of metals has occurred rather generally from industrial contamination and variably from intake of dietary mineral supplements. Adverse effects of individual metals can be markedly altered by dietary levels of other essential and nonessential inorganic elements, es...

journal_title：Environmental health perspectives

authors： Fox MR

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:The association of DDT (dichlorodiphenyltrichloroethane) with breast cancer is controversial, but animal studies directly linking DDT to risk are lacking. Concerns with DDT reside in its environmental persistence, bioaccumulation in breast adipose tissue, and endocrine-disrupting actions. Whereas most attent...

journal_title：Environmental health perspectives

authors： Johnson NA,Ho A,Cline JM,Hughes CL,Foster WG,Davis VL

更新日期：2012-08-01 00:00:00

abstract：:Exposure to air polluted with particles less than 2.5 micron in size is associated epidemiologically with adverse cardiopulmonary health consequences in humans. The goal of this study was to characterize human pulmonary responses to controlled experimental high-dose exposure to fine and ultrafine magnesium oxide parti...

journal_title：Environmental health perspectives

authors： Kuschner WG,Wong H,D'Alessandro A,Quinlan P,Blanc PD

更新日期：1997-11-01 00:00:00

abstract：:According to current data, the capacity to cause nonprogrammed or unscheduled cell proliferation in target tissues, a common characteristic of chemical carcinogens, may play a more important role in the development of tumors than does genotoxicity. This paper provides strong support for the validity of this conclusion...

journal_title：Environmental health perspectives

authors： Yoshikawa K

更新日期：1996-01-01 00:00:00

abstract：:Often a compound's biological activity is determined by complex relationships between its structural components. Such a relationship often can only be adequately described and exploited by multivariate structure-activity relationship (SAR) studies that can deal with many variables simultaneously. Pattern recognition (...

journal_title：Environmental health perspectives

authors： Stouch TR,Jurs PC

更新日期：1985-09-01 00:00:00

abstract：:The effects of inhaled zinc oxide/hexachloroethane smoke (11,580 mg x min/m3) and intratracheally instilled zinc chloride (2.5 mg/kg body weight) have been studied in rat lung. The effects of subsequent treatment with 70% oxygen have been studied after both procedures. Both the inhalation of the smoke and instillation...

journal_title：Environmental health perspectives

authors： Brown RF,Marrs TC,Rice P,Masek LC

更新日期：1990-04-01 00:00:00

abstract：:We used real-time monitors and low-volume air samplers to measure the potential human exposure to airborne polycyclic aromatic hydrocarbon (PAH) concentrations during various flight-related and ground-support activities of C-130H aircraft at an Air National Guard base. We used three types of photoelectric aerosol sens...

journal_title：Environmental health perspectives

authors： Childers JW,Witherspoon CL,Smith LB,Pleil JD

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Functional limitations are a major cause for needing care and institutionalization among older adults. Exposure to air pollution has been suggested to be associated with increased functional limitations in older people. OBJECTIVE:Our objective was to assess the association between air pollution and physical...

journal_title：Environmental health perspectives

authors： de Zwart F,Brunekreef B,Timmermans E,Deeg D,Gehring U

更新日期：2018-01-19 00:00:00

abstract：BACKGROUND:In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function. OBJECTIVES:We aimed to provide estimates of the effects of phthalate exposure on reproductiv...

journal_title：Environmental health perspectives

authors： Joensen UN,Frederiksen H,Blomberg Jensen M,Lauritsen MP,Olesen IA,Lassen TH,Andersson AM,Jørgensen N

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Sulfation plays an important role both in detoxification and in the control of steroid activity. Studies in rodents have shown that the conversion of dehydroepiandrosterone (DHEA) to DHEA-sulfate is involved in learning and the memory process. METHODS:The effects of a range of plasticizers and related compo...

journal_title：Environmental health perspectives

authors： Harris R,Turan N,Kirk C,Ramsden D,Waring R

更新日期：2007-12-01 00:00:00

abstract：:In 1998, the Helicobacter pylori [(13)C]urea breath test was offered to all school beginners (birth cohort 1991/1992) in the city of Leipzig and in Leipzig County, Germany, to determine the colonization prevalence and potential transmission pathways of the bacterium. A total of 3,347 school beginners participated in t...

journal_title：Environmental health perspectives

authors： Herbarth O,Krumbiegel P,Fritz GJ,Richter M,Schlink U,Müller DM,Richter T

更新日期：2001-06-01 00:00:00

abstract：:The carcinogenic properties of selected metals and their compounds are reviewed to provide a useful reference for existing knowledge on relationships between physical and chemical forms, kinetics and carcinogenic potential and between epidemiology, bioassays, and short-term tests. Extensive consideration is given to a...

journal_title：Environmental health perspectives

authors： Magos L

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:World Trade Center (WTC) rescue and recovery workers were exposed to a complex mix of pollutants and carcinogens. OBJECTIVE:The purpose of this investigation was to evaluate cancer incidence in responders during the first 7 years after 11 September 2001. METHODS:Cancers among 20,984 consented participants ...

journal_title：Environmental health perspectives

authors： Solan S,Wallenstein S,Shapiro M,Teitelbaum SL,Stevenson L,Kochman A,Kaplan J,Dellenbaugh C,Kahn A,Biro FN,Crane M,Crowley L,Gabrilove J,Gonsalves L,Harrison D,Herbert R,Luft B,Markowitz SB,Moline J,Niu X,Sacks H,

更新日期：2013-06-01 00:00:00

abstract：:Studies on the fate of 14C-labeled vinyl chloride (VC) following oral administration and inhalation exposure in rats demonstrated that the disposition of VC in the body is a function of the dose. More importantly, from the data available, it appears that a correlation exists between doses of VC which cause tumors and ...

journal_title：Environmental health perspectives

authors： Watanabe PG,Gehring PJ

更新日期：1976-10-01 00:00:00

abstract：:Adults eating a Western diet digest and absorb ingested food containing approximately 100 g fat, 350 g carbohydrate, and 75 g protein daily. Normal fat absorption requires adequate gastric, pancreatic, liver-biliary, mucosal, and lymphatic function. Carbohydrate and protein absorption is much less dependent on liver-b...

journal_title：Environmental health perspectives

authors： Heizer WD

更新日期：1979-12-01 00:00:00

abstract：:The potential danger of natural mercury accumulation in the diet of the Eskimo is evaluated through mercury levels determined in cord blood, placenta, maternal blood, hair, and milk of 38 maternal-infant pairs from Anchorage and the Yukon-Kuskokwim Delta. Although mercury levels are not discernably dangerous, trends t...

journal_title：Environmental health perspectives

authors： Galster WA

更新日期：1976-06-01 00:00:00

abstract：:Grafting experiments show that the enhanced sensitivity of the SENCAR mouse to skin carcinogenesis by initiation and promotion is a property of the skin itself, suggesting the usefulness of in vitro studies to elucidate the mechanism. Such studies have indicated that cultured epidermal cells of SENCAR mice and the res...

journal_title：Environmental health perspectives

authors： Strickland JE,Allen PT,Sauder DN,Kawamura H,Fong MC,Yuspa SH

更新日期：1986-09-01 00:00:00

abstract：:A major concern of the chlorination of aquatic humic materials is the ubiquitous production of trihalomethanes. A large number of other chlorinated organic compounds, however, have been shown to be formed by chlorine's reaction with humic substances. In this study, humic material was concentrated from a coastal North ...

journal_title：Environmental health perspectives

authors： Johnson JD,Christman RF,Norwood DL,Millington DS

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and...

journal_title：Environmental health perspectives

authors： Malloy TF,Zaunbrecher VM,Batteate CM,Blake A,Carroll WF Jr,Corbett CJ,Hansen SF,Lempert RJ,Linkov I,McFadden R,Moran KD,Olivetti E,Ostrom NK,Romero M,Schoenung JM,Seager TP,Sinsheimer P,Thayer KA

更新日期：2017-06-13 00:00:00

abstract：:Lead-induced nephropathy produces both tubular and interstitial manifestations of cell injury, but the pathophysiology of these lesions is not completely understood. Delineation of the molecular factors underlying renal handling of lead is one of central importance in understanding the mechanisms of renal cell injury ...

journal_title：Environmental health perspectives

authors： Fowler BA,DuVal G

更新日期：1991-02-01 00:00:00

abstract：:There is growing public pressure to minimize the use of vertebrates in ecotoxicity testing; therefore, effective alternatives to toxicity tests causing suffering are being sought. This report discusses alternatives and differs in some respects from the reports of the other three groups because the primary concern is w...

journal_title：Environmental health perspectives

authors： Walker C,Kaiser K,Klein W,Lagadic L,Peakall D,Sheffield S,Soldan T,Yasuno M

更新日期：1998-04-01 00:00:00

abstract：:The normal mucociliary epithelium of the respiratory tract in chronic cigarette smokers often is replaced focally by a metaplastic squamous epithelium. Because asbestos workers who smoke have a substantially greater risk of bronchogenic carcinoma than nonsmokers, we hypothesized that interaction of asbestos with squam...

journal_title：Environmental health perspectives

authors： Woodworth CD,Mossman BT,Craighead JE

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Exceptional aging, defined as reaching age 85 years, shows geographic inequalities that may depend on local environmental conditions. Links between particulate pollution-a well-recognized environmental risk factor-and exceptional aging have not been investigated. OBJECTIVES:We conducted a nationwide analysi...

journal_title：Environmental health perspectives

authors： Baccarelli AA,Hales N,Burnett RT,Jerrett M,Mix C,Dockery DW,Pope CA

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Ocean pollution affects marine organisms and ecosystems as well as humans. The International Oceanographic Commission recommends ocean health monitoring programs to investigate the presence of marine contaminants and the health of threatened species and the use of multiple and early-warning biomarker approac...

journal_title：Environmental health perspectives

authors： Godard-Codding CA,Clark R,Fossi MC,Marsili L,Maltese S,West AG,Valenzuela L,Rowntree V,Polyak I,Cannon JC,Pinkerton K,Rubio-Cisneros N,Mesnick SL,Cox SB,Kerr I,Payne R,Stegeman JJ

更新日期：2011-03-01 00:00:00

abstract：:Most of the composites and sealants used in dentistry are based on bisphenol A diglycidylether methacrylate (Bis-GMA). Reports revealed that in situ polymerization is not complete and that free monomers can be detected by different analytic methods. Concerns about the estrogenicity of bisphenol A (BPA) and other aroma...

journal_title：Environmental health perspectives

authors： Pulgar R,Olea-Serrano MF,Novillo-Fertrell A,Rivas A,Pazos P,Pedraza V,Navajas JM,Olea N

更新日期：2000-01-01 00:00:00