Effect of transient cyclic AMP elevation on DNA synthesis in rat hepatocytes at G1 phase.

abstract：BACKGROUND AND AIM:The fibrosis stage of non-alcoholic fatty liver disease (NAFLD) is closely associated with long-term prognosis, including liver-related mortality. However, it is not yet clear whether noninvasive fibrosis markers can predict the incidence of non-liver-related complications in Japanese NAFLD. In this ...

journal_title：Journal of gastroenterology and hepatology

authors： Ito T,Ishigami M,Ishizu Y,Kuzuya T,Honda T,Hayashi K,Nishimura D,Toyoda H,Kumada T,Goto H,Hirooka Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIM:Barrett's esophagus (BE) is a premalignant condition to esophageal adenocarcinoma. It is currently not clear whether cigarette smoking increases the risk of developing BE, and no meta-analysis has been performed on the topic. We conducted a systematic review and meta-analysis, providing a quantitativ...

journal_title：Journal of gastroenterology and hepatology

authors： Andrici J,Cox MR,Eslick GD

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Data on risk of hepatocellular carcinoma (HCC) in patients with Wilson disease are scarce. We determine HCC risk in a well-defined cohort of Wilson patients. METHODS:All patients with a confirmed diagnosis of Wilson disease (Leipzig score ≥ 4) in three Dutch university referral hospitals were inclu...

journal_title：Journal of gastroenterology and hepatology

authors： van Meer S,de Man RA,van den Berg AP,Houwen RH,Linn FH,van Oijen MG,Siersema PD,van Erpecum KJ

更新日期：2015-03-01 00:00:00

abstract：:Primary squamous cell carcinoma of the liver is very rare; only 18 cases have been recorded. In the present report we document an additional case who had a unique history of stage III non-keratinizing nasopharyngeal carcinoma treated with a full course of radiotherapy in July 1993. Two small hypoechoic cyst-like lesio...

journal_title：Journal of gastroenterology and hepatology

authors： Chou YY,Lee WJ,Su CT,Hsu HC

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND AIM:A substantial number of patients with gastroesophageal reflux disease show symptomatic resistance to high-dose proton pump inhibitors. In those cases, prokinetics are possible candidates for treatment. The aim of the present study was to determine whether mosapride, a prokinetic agent, stimulates eso...

journal_title：Journal of gastroenterology and hepatology

authors： Koshino K,Adachi K,Furuta K,Ohara S,Morita T,Nakata S,Tanimura T,Miki M,Kinoshita Y

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:We previously developed a new diagnostic method for Helicobacter pylori infection and called it the endoscopic [13C]-urea breath test (EUBT). Here we evaluate the relationship between the EUBT results and the histological findings. METHODS:The EUBT was performed on 137 patients with gastroduodenal diseases....

journal_title：Journal of gastroenterology and hepatology

authors： Suto H,Azuma T,Ito S,Ito Y,Miyaji H,Yamazaki Y,Kohli Y,Kuriyama M

更新日期：2000-02-01 00:00:00

abstract：:In November 2001, a 29-year-old woman was admitted to the hospital because of dysphagia due to an apallic state caused by cerebral anoxia. Nutritional support was maintained by nasogastric tube feeding for approximately 3 months. For improvement of the body state maintenance and quality of life, a percutaneous endosco...

journal_title：Journal of gastroenterology and hepatology

authors： Chen W,Kawahara H,Takahasi M,Matsushima A,Takase S

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known about the role of hepatitis B virus (HBV) factors in the long-term prognosis of hepatocellular carcinoma (HCC) after resection. The objective of the present study was to identify the changing patterns of HBV levels and its effect on outcome after resection. METHODS:This study recruit...

journal_title：Journal of gastroenterology and hepatology

authors： An HJ,Jang JW,Bae SH,Choi JY,Cho SH,Yoon SK,Han JY,Lee KH,Kim DG,Jung ES

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND AIM:Fusobacterium nucleatum (Fn) is involved in colorectal cancer (CRC) growth and is a biomarker for patient prognosis and management. However, the ecology of Fn in CRC and the distribution of intratumoral Fn are unknown. METHODS:We evaluated Fn and the status of KRAS and BRAF in 200 colorectal neoplas...

journal_title：Journal of gastroenterology and hepatology

authors： Yamamoto S,Kinugasa H,Hirai M,Terasawa H,Yasutomi E,Oka S,Ohmori M,Yamasaki Y,Inokuchi T,Harada K,Hiraoka S,Nouso K,Tanaka T,Teraishi F,Fujiwara T,Okada H

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic resection is highly effective treatment option for rectal neuroendocrine tumors (NETs) as they usually present as small localized tumors. However, there are no well-established surveillance strategies following endoscopic resection. We established our own protocol for the surveillance of r...

journal_title：Journal of gastroenterology and hepatology

authors： Chung HG,Goh MJ,Kim ER,Hong SN,Kim TJ,Chang DK,Kim YH

更新日期：2020-08-31 00:00:00

abstract：:The exact pathogenesis of centrilobular necrosis following congestion of the liver is still unknown. We reviewed the clinical data related to systemic circulatory disturbance and histopathology of the liver and the gut in 320 autopsy subjects. Congestion of the liver alone was associated only with atrophy and loss of ...

journal_title：Journal of gastroenterology and hepatology

authors： Shibayama Y,Urano T,Asaka S,Hashimoto K,Nakata K

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:A lack of published data remains on factors associated with the treatment response to proton pump inhibitors (PPI) in patients with non-erosive reflux disease (NERD). METHODS:Studies on effectiveness of PPI in patients with NERD were identified using the MEDLINE database and manual searches of the available...

journal_title：Journal of gastroenterology and hepatology

authors： Hiyama T,Matsuo K,Urabe Y,Fukuhara T,Tanaka S,Yoshihara M,Haruma K,Chayama K

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:This study investigated the usefulness of near-focus narrowband imaging (NF-NBI) for determining gastric tumor margins compared with indigo carmine chromoendoscopy (ICC) before endoscopic submucosal dissection (ESD). METHODS:This prospective randomized controlled trial was conducted at seven teachin...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JW,Jung Y,Jang JY,Kim GH,Bang BW,Park JC,Choi HS,Cho JH,Research Group for Endoscopic Instruments and Stents of Korean Society of Gastrointestinal Endoscopy.

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND AND AIM:Nonalcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may evolve into fibrosis or cirrhosis. Recent studies have shown reduction of experimental liver fibrosis with the use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor antagonists. The aim of this study w...

journal_title：Journal of gastroenterology and hepatology

authors： Ibañez P,Solis N,Pizarro M,Aguayo G,Duarte I,Miquel JF,Accatino L,Arrese M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The classification of gastritis by using the revised Sydney system suggests that there are two types of Helicobacter pylori-related gastritis. The aim of the present study was to examine the risk factors that might be involved in the presence of either atrophic gastritis or intestinal metaplasia of ...

journal_title：Journal of gastroenterology and hepatology

authors： Tsukui T,Kashiwagi R,Sakane M,Tabata F,Akamatsu T,Wada K,Futagami S,Miyake K,Sueoka N,Hirakawa T,Kobayashi M,Fujimori T,Sakamoto C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIM:Increased production of reactive oxygen species, which cause oxidative DNA damage, is considered to be related to hepatocarcinogenesis. 8-Hydroxy-2'-deoxy-guanosine (8-OHdG) is a useful marker of DNA damage induced by oxidative stress. The aim of this study was to determine whether expression of 8-OH...

journal_title：Journal of gastroenterology and hepatology

authors： Chuma M,Hige S,Nakanishi M,Ogawa K,Natsuizaka M,Yamamoto Y,Asaka M

更新日期：2008-09-01 00:00:00

abstract：:Cancer stem cells (CSC) have been identified in a growing number of human malignancies. CSC are functionally defined by their ability to self-renew and recapitulate tumors in the ectopic setting, and a growing number of studies have shown that they display other functional characteristics, such as invasion and drug re...

journal_title：Journal of gastroenterology and hepatology

authors： Rasheed ZA,Matsui W

更新日期：2012-03-01 00:00:00

abstract：:Antipyrine metabolism is widely used as an index of the drug-metabolizing reserve of the liver. It is well known that metabolism of this drug is impaired in subjects with acute hepatitis or cirrhosis, but conflicting data have been reported regarding patients with chronic postinfectious hepatitis or liver cancer. We s...

journal_title：Journal of gastroenterology and hepatology

authors： Grieco A,Castellano R,Matera A,Marcoccia S,Di Rocco P,Ragazzoni E,Vecchio FM,Gasbarrini G

更新日期：1998-05-01 00:00:00

abstract：AIM:To investigate the morphological changes of intratumoral microvessels after administration of thalidomide in occult hepatic metastases. METHODS:Twenty mice with hepatic metastases created by injection of colon-26 tumor cells into the spleen were enrolled. Ten mice were treated with thalidomide (200 mg/kg) by intra...

journal_title：Journal of gastroenterology and hepatology

authors： Liu Y,Li H,Matsui O

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND & AIMS:Both medications with beta-blockers and isosorbide-5-mononitrate and endoscopic variceal ligation have been proven plausible in the prevention of variceal rebleeding. However, the relative efficacy and safety of the combined treatment for preventing rebleeding remains unresolved. METHODS:Patients wit...

journal_title：Journal of gastroenterology and hepatology

authors： Lo GH,Chen WC,Chan HH,Tsai WL,Hsu PI,Lin CK,Chen TA,Lai KH

更新日期：2009-06-01 00:00:00

abstract：:There is some evidence of an antagonism between peptic ulcer and diabetes mellitus. This antagonism is possibly related to anomalous insulin metabolism in duodenal ulcer patients. To evaluate this issue, 471 Rochester, Minnesota residents who had surgery for peptic ulcer were examined and then followed for up to 34 ye...

journal_title：Journal of gastroenterology and hepatology

authors： Duggan JM,O'Keefe EA,Weaver AL,Zinsmeister AR,Melton LJ 3rd

更新日期：1992-05-01 00:00:00

abstract：:During 1981-86, 76 children were diagnosed as having acute viral hepatitis at the Department of Pediatrics, National Taiwan University Hospital, which is a major referral centre for hepatitis in children in northern Taiwan. The majority (64%) of children had acute hepatitis B which had occurred mainly during infancy. ...

journal_title：Journal of gastroenterology and hepatology

authors： Huang LM,Chang MH,Hong JY,Lee CY,Chen DS

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:There are clinical reports that Helicobacter heilmannii, as well as Helicobacter pylori, has been clinically reported to cause gastric low-grade mucosa-associated lymphoid tissue-type (MALT) lymphoma, although its precise mechanism remains to be clarified. Thus, the present study was undertaken to elucidate ...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura M,Takahashi S,Matsui H,Murayama SY,Aikawa C,Sekiya Y,Nishikawa K,Matsumoto T,Yamada H,Tsuchimoto K

更新日期：2008-12-01 00:00:00

abstract：:Flexible sigmoidoscopy has been recommended as a screening method to reduce the incidence of colorectal cancer in asymptomatic, average-risk subjects through the early detection and removal of polyps. However, the association between distal and proximal colonic neoplasia and, hence, the requirement for colonoscopic fo...

journal_title：Journal of gastroenterology and hepatology

authors： Collett JA,Platell C,Fletcher DR,Aquilia S,Olynyk JK

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND AIM:Dendritic cells (DCs) are observed on the Helicobacter pylori-infected gastric mucosa. DCs generally play an important role in the regulation of inflammation. Although stimulation of gastric epithelial cells with H. pylori vacuolating cytotoxin (VacA) has been reported to induce apoptosis and endopla...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JM,Kim JS,Kim N,Ko SH,Jeon JI,Kim YJ

更新日期：2015-01-01 00:00:00

abstract：UNLABELLED:A case-control study was conducted in southern Thailand to test the hypothesis that alcohol consumption, smoking, rubber processing and nutritional deficiency were risk factors for oesophageal cancer. Cases (n = 40) were recruited from patients admitted to the University Hospital, where the first interview t...

journal_title：Journal of gastroenterology and hepatology

authors： Chongsuvivatwong V

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer (CRC) screening is based on colonoscopy or fecal occult blood tests, but is imperfect and costly. The Asia Pacific Colorectal Screening Score (APCS) is derived from age, sex, family history of CRC, and smoking history and has been validated in Asian populations. Validation in a West...

journal_title：Journal of gastroenterology and hepatology

authors： Corte C,Zhang L,Chen J,Westbury S,Shaw J,Yeoh KG,Leong R

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND AIM:Immunization against hepatitis B virus (HBV) infection is recommended in patients with inflammatory bowel disease (IBD), particularly in those under immunosuppressive therapy. Limited data are available about IBD patient's response to HBV vaccination. We assessed the response rate to HBV vaccination ...

journal_title：Journal of gastroenterology and hepatology

authors： Andrade P,Santos-Antunes J,Rodrigues S,Lopes S,Macedo G

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND AIM:It has been reported that the branched-chain amino acid (BCAA) to tyrosine ratio (BTR) is a useful indicator of liver function and BCAA therapy is associated with a decreased incidence of hepatocellular carcinoma (HCC). However, there has not been sufficient research on the relationship between BTR a...

journal_title：Journal of gastroenterology and hepatology

authors： Tada T,Kumada T,Toyoda H,Kiriyama S,Tanikawa M,Hisanaga Y,Kanamori A,Kitabatake S,Yama T

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND AIM:The role of octamer-binding transcription factor 4 (Oct4) has been implicated in the clinical prognosis of various kinds of digestive system cancers, but the results remain controversial. The purpose of this meta-analysis is to assess the potential role of Oct4 as a prognostic marker in digestive sys...

journal_title：Journal of gastroenterology and hepatology

authors： Chen Z,Zhang L,Zhu Q,Wang X,Wu J,Wang X

更新日期：2017-03-01 00:00:00