Helicobacter pylori vacuolating cytotoxin induces apoptosis via activation of endoplasmic reticulum stress in dendritic cells.

abstract：BACKGROUND AND AIM:Same-day bidirectional endoscopy (BDE) is a commonly performed procedure, but the optimal sequence for the procedure with moderate conscious sedation is not well established. This study investigated the optimal sequence for same-day BDE under moderate conscious sedation and carbon dioxide insufflatio...

journal_title：Journal of gastroenterology and hepatology

authors： Chen SW,Cheng CL,Liu NJ,Tang JH,Kuo YL,Lin CH,Tsui YN,Lee BP,Hung HL

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:The role of psychological disturbance in the pathogenesis of functional dyspepsia is uncertain. We aimed to examine for differences in anxiety, depression and health-related quality of life (HRQOL) between adults with organic (OD) and functional dyspepsia (FD). METHODOLOGY:A prospective, cross...

journal_title：Journal of gastroenterology and hepatology

authors： Mahadeva S,Goh KL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer screening is recommended for average-risk persons beginning at age 50. However, information about the incidence and risk factors of precursor adenoma in preceding decades is limited. The aim of this study was to determine the prevalence and risk factors of colorectal adenoma in pers...

journal_title：Journal of gastroenterology and hepatology

authors： Chung SJ,Kim YS,Yang SY,Song JH,Park MJ,Kim JS,Jung HC,Song IS

更新日期：2010-03-01 00:00:00

abstract：:One of the characteristic features of the majority of pancreatic ductal adenocarcinomas is an abundant desmoplastic/stromal reaction. Until recently, this stroma had received little attention from researchers studying the pathogenesis of pancreatic cancer, with most of the research focus resting on the biology of tumo...

journal_title：Journal of gastroenterology and hepatology

authors： Apte MV,Wilson JS

更新日期：2012-03-01 00:00:00

abstract：:Acute cholangitis is associated with significant morbidity and mortality. Endoscopic drainage procedures have been shown to be a safe and effective mode of treatment in acute cholangitis. As there is paucity of large series on endoscopic management of acute cholangitis, a study was performed to evaluate safety and eff...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma BC,Agarwal DK,Baijal SS,Saraswat VA,Choudhuri G,Naik SR

更新日期：1997-12-01 00:00:00

abstract：:At Royal Perth Hospital, Western Australia in April 1982, spiral bacteria were first cultured from a gastric biopsy specimen. Several important taxonomic features were identified which indicated that these bacteria represented a new genus. In October 1989 the new genus name Helicobacter was published. Helicobacter pyl...

journal_title：Journal of gastroenterology and hepatology

authors： Goodwin CS

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Th17 cells have been shown to mediate host defensive mechanisms in various infections, but their role in HBV infection in humans has not been well characterized. In this study, we analyzed the frequency and cytokines secretion of circulating Th17 cells in HBV infected patients with different statuse...

journal_title：Journal of gastroenterology and hepatology

authors： Wu W,Li J,Chen F,Zhu H,Peng G,Chen Z

更新日期：2010-04-01 00:00:00

abstract：:Acid-sensing pathways, which trigger mucosal defense mechanisms in response to luminal acid, involve the rapid afferent-mediated "capsaicin pathway" and the sustained "prostaglandin (PG) pathway." Luminal acid quickly increases protective PG synthesis and release from epithelia, although the mechanism by which luminal...

journal_title：Journal of gastroenterology and hepatology

authors： Akiba Y,Kaunitz JD

更新日期：2014-12-01 00:00:00

abstract：:Alcoholic liver diseases (ALD) are frequently associated with iron overload. Until recently, the effects of ethanol in hepatic iron uptake and intestinal iron absorption have not been clarified in detail. Two possible mechanisms for iron overload are the uptake of iron into hepatocytes in a specific manner through the...

journal_title：Journal of gastroenterology and hepatology

authors： Kohgo Y,Ohtake T,Ikuta K,Suzuki Y,Torimoto Y,Kato J

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND AIM:Host genetic factors have been reported as influencing the progress to fulminant hepatitis (FH). Our previous data showed the serum level of tumor necrosis factor (TNF)-alpha influenced by gene polymorphisms to be markedly increased. It was investigated whether polymorphisms in the IL-10 gene, in add...

journal_title：Journal of gastroenterology and hepatology

authors： Takakura M,Tokushige K,Matsushita N,Hashimoto E,Shiratori K

更新日期：2007-08-01 00:00:00

abstract：:Gilbert's syndrome, an hereditary, chronic, mild, unconjugated hyperbilirubinaemia resulting from impaired hepatic bilirubin clearance and otherwise normal liver function, is arguably the most common syndrome known in humans. Recent molecular genetic studies have determined that the clinical phenotype can be described...

journal_title：Journal of gastroenterology and hepatology

authors： Burchell B,Hume R

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND AIM:After selective biliary access following precut fistulotomy in difficult biliary cannulations (DBC), there are several methods of completely opening the remaining papillary roof for the removal of biliary stones. We evaluated the efficacy of one-step transfistula balloon dilation following fistulotom...

journal_title：Journal of gastroenterology and hepatology

authors： Jun BG,Lee TH,Jeong S,Hwang JC,Yang MJ,Song TJ,Choi HJ,Moon JH,Park SH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Collagenous sprue (CS) is a rare form of enteropathy that had been reported to be associated with celiac disease (CD) and collagenous colitis (CC). The aim of our study was to compare the clinical features, treatments, and outcomes of CS, CD, and CC. METHODS:All patients with histologic diagnosis of CS, CD,...

journal_title：Journal of gastroenterology and hepatology

authors： Lan N,Shen B,Yuan L,Liu X

更新日期：2017-01-01 00:00:00

abstract：:To clarify the contribution of peritoneal absorption of enzyme-rich exudate to the persistent elevation of serum amylase in bile-induced pancreatitis in dogs, serum amylase, lipase and immunoreactive trypsin (IRT) levels were measured during 24 h after induction of pancreatitis with and without peritoneal lavage. The ...

journal_title：Journal of gastroenterology and hepatology

authors： Sugimoto Y,Hayakawa T,Kondo T,Shibata T,Kishimoto W

更新日期：1990-09-01 00:00:00

abstract：:Iatrogenic superior mesenteric arteriovenous fistula is rare. We treated a patient with this problem 6 years after small bowel resection for intestinal obstruction. The symptoms and signs were those of intestinal ischaemia and portal hypertension with an abdominal bruit. Ultrasonography and enhanced computerized tomog...

journal_title：Journal of gastroenterology and hepatology

authors： Iwai M,Kashiwadani M,Suyama Y,Miyoshi M,Kashima K

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND AND AIM:Histological criteria for intracapsular venous invasion (IVI) that would allow its discrimination between portal and hepatic venous invasion in hepatocellular carcinoma (HCC) have not been established. METHODS:We evaluated IVI immunohistochemically to discriminate between portal and hepatic venous i...

journal_title：Journal of gastroenterology and hepatology

authors： Ohashi M,Wakai T,Korita PV,Ajioka Y,Shirai Y,Hatakeyama K

更新日期：2010-01-01 00:00:00

abstract：:The mechanism of phagocytosis by Kupffer cells has been shown to be related to the Ca(2+)-calmodulin and the actomyosin systems. However the role of the transmembrane signal transmitter, G-protein, is still unknown. In this study, a quantitative evaluation of phagocytosis by Kupffer cells of rats in culture and the ef...

journal_title：Journal of gastroenterology and hepatology

authors： Hirose M,Watanabe S,Ueno T,Kitami N,Sato N

更新日期：1993-07-01 00:00:00

abstract：:Typhoid fever is often associated with abnormal liver biochemical tests, but severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. There have been more than 150 cases of salmonella hepatitis reported from both developed and developing countries. The documented incidence varies w...

journal_title：Journal of gastroenterology and hepatology

authors： Pramoolsinsap C,Viranuvatti V

更新日期：1998-07-01 00:00:00

abstract：:Low-dose aspirin (ASA) has emerged as one of the most important causes of peptic ulcer bleeding in developed countries. Among the risk factors of ASA-associated ulcer bleeding, Helicobacter pylori infection is one of the few that is treatable. Recent evidence showed that among patients with a history of ASA-associated...

journal_title：Journal of gastroenterology and hepatology

authors： Chan FK

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIM:Few studies have evaluated sustained virological response (SVR) rates by direct-acting agents (DAAs) and liver stiffness measurement (LSM) changing post-SVR in limited-resource settings. We aimed to describe the effectiveness of DAAs for hepatitis C virus treatment and to assess the changing of LSM p...

journal_title：Journal of gastroenterology and hepatology

authors： Fernandes FF,Piedade J,Guimaraes L,Nunes EP,Chaves U,Goldenzon RV,Cardoso SW,Duarte J,Grinsztejn B,Veloso VG,Pereira G,Perazzo H

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

journal_title：Journal of gastroenterology and hepatology

authors： Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND/AIMS:Psychological factors and subtle histopathological changes have been implicated in irritable bowel syndrome (IBS). The aims of the present study were to investigate whether the numbers of enterochromaffin (EC) cells, mast cells, and lamina propria T lymphocytes are altered in IBS, and evaluate the relat...

journal_title：Journal of gastroenterology and hepatology

authors： Lee KJ,Kim YB,Kim JH,Kwon HC,Kim DK,Cho SW

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:The liver is the major iron storage organ in the body and, as a result, total body iron stores closely regulate hepatocyte iron uptake, storage and release. Transferrin, transferrin receptor and ferritin facilitate these processes. METHODS:Expression of the three proteins was localized by immunohistochemist...

journal_title：Journal of gastroenterology and hepatology

authors： Basclain KA,Jeffrey GP

更新日期：1999-07-01 00:00:00

abstract：:A 34 year old man with glycogen storage disease type 1a had two hepatic tumours since 18 years of age. They had continued to grow until he was 24 years old, but showed no further growth since then. He underwent a right hepatic trisegmentectomy with caudate lobectomy under veno-venous bypass. The tumour in the posterio...

journal_title：Journal of gastroenterology and hepatology

authors： Moriura S,Kuroda M,Kimura A,Iwatsuka Y,Ikeda S,Sakai T,Usui A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of peginterferon alpha-2a (40 KD) (peg-IFNalpha-2a) plus ribavirin has not been reported for Japanese patients with chronic hepatitis C. The aim of this study was to evaluate this combination in treatment-naïve patients and in non-responders or relapsers to interferon monotherapy. ME...

journal_title：Journal of gastroenterology and hepatology

authors： Kuboki M,Iino S,Okuno T,Omata M,Kiyosawa K,Kumada H,Hayashi N,Sakai T

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIM:Simultaneous and metachronous head and neck cancers are likely to develop in patients with current or previous esophageal cancer. The Valsalva maneuver facilitates the visualization of the hypopharyngeal area during endoscopic observation, but it requires transnasal endoscopy. We developed a novel Va...

journal_title：Journal of gastroenterology and hepatology

authors： Iwatsubo T,Ishihara R,Nakagawa K,Ohmori M,Iwagami H,Matsuno K,Inoue S,Nakahira H,Matsuura N,Shichijo S,Maekawa A,Kanesaka T,Yamamoto S,Takeuchi Y,Higashino K,Uedo N,Higuchi K

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:: Previously, we have observed that highly unsaturated dietary (n-3) fatty acids inhibit cell proliferation in conjunction with stimulation of insulin-like growth factor-binding protein (IGFBP)-6 secretion in Caco-2 cells, a human colon carcinoma cell line. METHODS:: To test the converse hypothesis that inh...

journal_title：Journal of gastroenterology and hepatology

authors： Kim EJ,Schaffer BS,Kang YH,Macdonald RG,Park JH

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The efficiency of Helicobacter pylori eradication varies geographically, as do many parameters that might affect therapeutic efficiency. The aims of this study were to investigate the relationship between different genotypes of H. pylori and bacterium-related histopathological lesions in patients with duoden...

journal_title：Journal of gastroenterology and hepatology

authors： Zhao JJ,Wang JB,Yang L,Li Y

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND AIM:Real-world data on sofosbuvir/velpatasvir with and without ribavirin (SOF/VEL ± RBV), particularly among patients with genotype 3 (GT3) decompensated cirrhosis, prior treatment, coinfection, and hepatocellular carcinoma (HCC), are scarce. We aimed to assess the efficacy and safety of SOF/VEL ± RBV in...

journal_title：Journal of gastroenterology and hepatology

authors： Wong YJ,Thurairajah PH,Kumar R,Tan J,Fock KM,Law NM,Li W,Kwek A,Tan YB,Koh J,Lee ZC,Kumar LS,Teo EK,Ang TL

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND AND AIM:Approximately 42-95% of working channels have been reported to show the presence of residual fluid despite endoscope reprocessing. The aim of this study was to design two novel protocols for cleaning residual simethicone and demonstrate its efficiency by evaluating the residual fluid and cleanliness ...

journal_title：Journal of gastroenterology and hepatology

authors： Peng CL,Liu TC,Wang HP,Chang WK

更新日期：2020-12-03 00:00:00