Anxiety, depression and quality of life differences between functional and organic dyspepsia.

abstract：BACKGROUND AND AIM:Helicobacter pylori (H. pylori) infection is a strong risk factor for the development of gastric cancer. In 2013, the Japanese government approved H. pylori eradication therapy in patients with chronic gastritis as well as peptic ulcer. However, the continuing decline in eradication rates for first-l...

journal_title：Journal of gastroenterology and hepatology

authors： Kawai T,Takahashi S,Suzuki H,Sasaki H,Nagahara A,Asaoka D,Matsuhisa T,Masaoaka T,Nishizawa T,Suzuki M,Ito M,Kurihara N,Omata F,Mizuno S,Torii A,Kawakami K,Ohkusa T,Tokunaga K,Mine T,Sakaki N

更新日期：2014-12-01 00:00:00

abstract：:Recent autopsy studies have clarified the frequency of lymph node (LN) metastases from hepatocellular carcinoma (HCC). However, LN metastases commonly occur in advanced and poorly differentiated HCC and are very rare in small HCC. We encountered a patient with skip LN metastases from a small HCC, 10 mm in diameter. An...

journal_title：Journal of gastroenterology and hepatology

authors： Uehara K,Hasegawa H,Ogiso S,Sakamoto E,Ohira S,Igami T,Mori T

更新日期：2003-03-01 00:00:00

abstract：:Since receptor-binding cancer antigen expressed on SiSo cells (RCAS1) was first reported as a tumor-associated antigen of gynecologic cancer, its function and practical value as a tumor marker have been investigated in various types of carcinomas. Basic research has indicated that RCAS1 expression in cancer cells cont...

journal_title：Journal of gastroenterology and hepatology

authors： Enjoji M,Nakashima M,Yamaguchi K,Kotoh K,Nakamuta M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic alcoholic liver disease is associated with hepatic insulin resistance, dysregulated lipid metabolism with increased toxic lipid (ceramide) accumulation, lipid peroxidation, and oxidative and endoplasmic reticulum (ER) stress. Peroxisome-proliferator activated receptor (PPAR) agonists are insu...

journal_title：Journal of gastroenterology and hepatology

authors： Ramirez T,Tong M,Chen WC,Nguyen QG,Wands JR,de la Monte SM

更新日期：2013-01-01 00:00:00

abstract：:To clarify the contribution of peritoneal absorption of enzyme-rich exudate to the persistent elevation of serum amylase in bile-induced pancreatitis in dogs, serum amylase, lipase and immunoreactive trypsin (IRT) levels were measured during 24 h after induction of pancreatitis with and without peritoneal lavage. The ...

journal_title：Journal of gastroenterology and hepatology

authors： Sugimoto Y,Hayakawa T,Kondo T,Shibata T,Kishimoto W

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND AND AIM:The fibrosis stage of non-alcoholic fatty liver disease (NAFLD) is closely associated with long-term prognosis, including liver-related mortality. However, it is not yet clear whether noninvasive fibrosis markers can predict the incidence of non-liver-related complications in Japanese NAFLD. In this ...

journal_title：Journal of gastroenterology and hepatology

authors： Ito T,Ishigami M,Ishizu Y,Kuzuya T,Honda T,Hayashi K,Nishimura D,Toyoda H,Kumada T,Goto H,Hirooka Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic screening for esophageal varices (EVs) is expensive and invasive. Besides traditional noninvasive markers, we explore additional candidate markers including portal hypertension serum marker-soluble CD136 (sCD163) and genetic variants of splanchnic vasodilatation and revascularization pathw...

journal_title：Journal of gastroenterology and hepatology

authors： Yang YY,Hou MC,Lin MW,Chen PH,Liao WC,Chu CJ,Lin HC

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Epithelial-mesenchymal transition (EMT) of biliary epithelial cells (BECs) plays an important role in biliary fibrosis. This study investigated the effects of simvastatin on the lipopolysaccharide (LPS)-induced EMT and related signal pathways in BECs. METHODS:Biliary epithelial cells were exposed to...

journal_title：Journal of gastroenterology and hepatology

authors： Kim Y,Lee EJ,Jang HK,Kim CH,Kim DG,Han JH,Park SM

更新日期：2016-06-01 00:00:00

abstract：:To ascertain whether acid inhibition or Helicobacter pylori (HP) colonization is the decisive factor in the healing of duodenal ulcer, we treated 54 patients with famotidine and carried out long-term follow-up. Helicobacter pylori colonization was found in 70.4% of patients before treatment. There were no differences ...

journal_title：Journal of gastroenterology and hepatology

authors： Lai KH,Chang FY,Tsay SH,Lu LC,Cheng JT,Jeng SS,Wu TC,Ng WW,Jeng JS,Lee SD

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Uncoupling protein-2 (UCP-2) is a negative regulator of reactive oxygen species (ROS) production. We investigated the effect of UCP-2 on disease progression in a murine dextran sodium sulfate (DSS)-induced colitis model, and the expression and distribution of tight junction (TJ) proteins, such as oc...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang H,Kuai XY,Yu P,Lin L,Shi R

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Th17 cells have been shown to mediate host defensive mechanisms in various infections, but their role in HBV infection in humans has not been well characterized. In this study, we analyzed the frequency and cytokines secretion of circulating Th17 cells in HBV infected patients with different statuse...

journal_title：Journal of gastroenterology and hepatology

authors： Wu W,Li J,Chen F,Zhu H,Peng G,Chen Z

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND AIM:By array-comparative genomic hybridization, we demonstrated cyclin E as one of seven genes associated with hepatocellular carcinoma (HCC) development in Ku70 DNA repair-deficient mice. We therefore explored the hypothesis that during hepatocarcinogenesis, cyclin E kinase can overcome the inhibitory e...

journal_title：Journal of gastroenterology and hepatology

authors： Pok S,Wen V,Shackel N,Alsop A,Pyakurel P,Fahrer A,Farrell GC,Teoh NC

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Both clinical outcomes and factors predictive for poor response after an initial course of corticosteroids have not yet been well established in the treatment of moderate to severe ulcerative colitis (UC). We therefore evaluated the short- and long-term effects of corticosteroids and prognostic fact...

journal_title：Journal of gastroenterology and hepatology

authors： Yoon JY,Cheon JH,Park JJ,Hong SP,Kim TI,Kim WH

更新日期：2011-07-01 00:00:00

abstract：:The Epstein-Barr virus (EBV) has been reported to be detectable in about 10% of gastric carcinomas. We performed a comparative study of endosonographic findings of EBV-positive and -negative early gastric carcinomas. Epstein-Barr virus was detected in 11.8% (four of 34) of endosonographically observed early gastric ca...

journal_title：Journal of gastroenterology and hepatology

authors： Nishikawa J,Yanai H,Mizugaki Y,Takada K,Tada M,Okita K

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND AIMS:It is well known that endotoxemia, which is caused by a bacterial infection, can exacerbate acute pancreatitis, whereas pancreatitis-associated protein (PAP) has the ability to induce bacterial aggregation. Pancreatitis-associated protein is supposed to protect the tissue from infection during infla...

journal_title：Journal of gastroenterology and hepatology

authors： Wang X,Wang B,Wu J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal endoscopic submucosal dissection (ESD) is used for the treatment of large colorectal superficial neoplasms. However, there have been no large studies on electrocoagulation syndrome developing after colorectal ESD. The aim of this study was to clarify the incidence and clinical risk factors...

journal_title：Journal of gastroenterology and hepatology

authors： Ito S,Hotta K,Imai K,Yamaguchi Y,Kishida Y,Takizawa K,Kakushima N,Tanaka M,Kawata N,Yoshida M,Ishiwatari H,Matsubayashi H,Ono H

更新日期：2018-12-01 00:00:00

abstract：:Extraesophageal manifestations of gastroesophageal reflux disease (GERD) are essentially complications of GERD that primarily involve organs that are in proximity to the esophagus. Non-cardiac chest pain (NCCP) is an atypical manifestation of GERD, because symptoms originate in essence from the esophagus. In both atyp...

journal_title：Journal of gastroenterology and hepatology

authors： Wong WM,Fass R

更新日期：2004-09-01 00:00:00

abstract：:The author visited China in 1981 and 1984 and obtained data comparing the incidence of duodenal ulcer in the rice eating districts of the south with the incidence in the wheat, maize and millet eating areas of the north. The evidence suggested a higher prevalence of duodenal ulcer in the rice eating areas than in the ...

journal_title：Journal of gastroenterology and hepatology

authors： Tovey FI

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND AIM:Recently, microRNAs (miRNA) have been linked to the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH). First transcribed as pri-miRNA, these molecules are further processed by a complex of endonuclear and cytosolic RNA binding molecu...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma H,Estep M,Birerdinc A,Afendy A,Moazzez A,Elariny H,Goodman Z,Chandhoke V,Baranova A,Younossi ZM

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Saccharomyces cerevisiae may contribute to the pathophysiology of Crohn's disease. We determined serum anti-Saccharomyces cerevisiae antibody (ASCA) levels in patients with inflammatory bowel disease. METHODS AND RESULTS:Immunoglobulin G (IgG) ASCA was measured by using an ELISA in serum samples from 19 pat...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Hato F,Matsumoto T,Jinno Y,Sawa Y,Hara J,Nakamura S,Seki S,Arakawa T,Kitano A,Kitagawa S,Kuroki T

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND AND AIM:The most effective schedule of proton pump inhibitor (PPI) administration and the optimal timing of endoscopy in acute peptic ulcer bleeding remain uncertain. The aim of this study was to determine the most efficient PPI regimen and optimal timing of endoscopy. METHODS:  Consecutive patients with su...

journal_title：Journal of gastroenterology and hepatology

authors： Liu N,Liu L,Zhang H,Gyawali PC,Zhang D,Yao L,Yang Y,Wu K,Ding J,Fan D

更新日期：2012-09-01 00:00:00

abstract：:Ulcerative colitis (UC) and Crohn's disease (CD) comprise the idiopathic inflammatory bowel diseases (IBD) of the gut. The etiology of IBD is poorly understood, but an autoimmune disturbance has been suggested to play an important role in this incurable disease. Extracorporeal leukocytapheresis (CAP) is an additional ...

journal_title：Journal of gastroenterology and hepatology

authors： Fukunaga K,Matsumoto T

更新日期：2012-06-01 00:00:00

abstract：:The hepatitis C virus was first identified in 1989. It causes chronic hepatitis, cirrhosis and hepatocellular carcinoma. Global anti-HCV prevalence is 1-3%. Contaminated blood product, dirty needles and instruments, and injection drug use are the main parenteral routes of transmission. Cultural practices, such as acup...

journal_title：Journal of gastroenterology and hepatology

authors： Leung NW

更新日期：2002-02-01 00:00:00

abstract：:A novel experimental model of submassive liver necrosis with impaired regeneration has been established. A novel lipid A analogue, FS-112, was injected intravenously into male BALB/c mice, followed 2 days later by a 70% partial hepatectomy. Over the next 9 days, mice became severely jaundiced, with a peak total biliru...

journal_title：Journal of gastroenterology and hepatology

authors： Maeda T,Ohnishi H,Hayashi T,Ishiki Y,Moriwaki H,Muto Y

更新日期：1996-05-01 00:00:00

abstract：:Chronic pancreatitis (CP) is a disease characterized by irreversible destruction and fibrosis of the parenchyma, leading to pancreatic exocrine insufficiency. In developed countries, the etiology for 60% to 70% of CP amongst male patients is alcohol and 25% are classified as idiopathic chronic pancreatitis (ICP). The ...

journal_title：Journal of gastroenterology and hepatology

authors： Reddy DN,Prasad SS

更新日期：2011-03-01 00:00:00

abstract：:This study evaluates the immune response of 20 haemodialysis (HD) patients vaccinated with hepatitis A (HA) vaccine and eight patients vaccinated with hepatitis B (HB) vaccine. Twenty patients and 22 healthy adults were immunized three times (months 0, 1 and 6) intramuscularly with a 0.5 microgram dose. All members of...

journal_title：Journal of gastroenterology and hepatology

authors： Kuramoto I,Fujiyama S,Matsushita K,Sato T

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Colorectal laterally spreading tumors (LST) > 20 mm are usually treated by endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR). Endoscopic piecemeal mucosal resection (EPMR) is sometimes required. The aim of our study was to compare the outcomes of ESD and EMR, including EPM...

journal_title：Journal of gastroenterology and hepatology

authors： Terasaki M,Tanaka S,Oka S,Nakadoi K,Takata S,Kanao H,Yoshida S,Chayama K

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The CLOtest and other rapid urease detection kits are widely used in the endoscopic diagnosis of Helicobacter pylori. A new formulation CLOtest has been developed with the goal of obtaining a positive result more rapidly. The aims of this study were to validate the sensitivity and specificity of the...

journal_title：Journal of gastroenterology and hepatology

authors： Viiala CH,Windsor HM,Forbes GM,Chairman SO,Marshall BJ,Mollison LC

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIM:Few studies have evaluated sustained virological response (SVR) rates by direct-acting agents (DAAs) and liver stiffness measurement (LSM) changing post-SVR in limited-resource settings. We aimed to describe the effectiveness of DAAs for hepatitis C virus treatment and to assess the changing of LSM p...

journal_title：Journal of gastroenterology and hepatology

authors： Fernandes FF,Piedade J,Guimaraes L,Nunes EP,Chaves U,Goldenzon RV,Cardoso SW,Duarte J,Grinsztejn B,Veloso VG,Pereira G,Perazzo H

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:We designed an animal model in order to clarify whether Helicobacter pylori infection causes the gastric mucosal lesion frequently seen in cirrhotic patients. METHODS:Ammonia (NH3) solution was given to rats with carbon tetrachloride-induced cirrhosis. The gastric mucosal hexosamine (Hx) content and histopa...

journal_title：Journal of gastroenterology and hepatology

authors： Sugimoto M,Machida Y,Ito K

更新日期：1999-06-01 00:00:00