Abstract：
:The second phase of Ca2+ transients (aequorin luminescence) which was not accompanied by twitch tensions were generated by 0.3 microM neostigmine in indirectly-stimulated diaphragm muscles of mice. This phase was dependent on external [Ca2+]o, was inhibited by a low concentration of (+)-tubocurarine (+)-TC; 0.013-0.13 microM) or pancuronium (Panc; 0.034-0.14 microM), and was not inhibited by atropine (3 microM) or nitrendipine (10 microM). These results suggest that nicotinic acetylcholine receptor highly sensitive to (+)-TC may stimulate Ca2+ influx through receptor-operated Ca2+ channels.
journal_name
Brain Resjournal_title
Brain researchauthors
Kimura I,Kondoh T,Kimura Mdoi
10.1016/0006-8993(90)90287-lsubject
Has Abstractpub_date
1990-01-22 00:00:00pages
309-11issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(90)90287-Ljournal_volume
507pub_type
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