当前位置： SCI文献检索 > DIABETES RESEARCH AND CLINICAL PRACTICE期刊下所有文献 > Tumor necrosis factor alpha -238G/A (rs 361525) gene polymorphism predicts progression to type-2 diabetes in an Eastern Indian population with prediabetes.

Tumor necrosis factor alpha -238G/A (rs 361525) gene polymorphism predicts progression to type-2 diabetes in an Eastern Indian population with prediabetes.

Abstract：

:Prediabetes (IPD; n=122) and normoglycemic individuals (n=100) underwent assessment of polymorphisms of TNFα (-238, -308) and IL6 (-174). After 27.25±5.64 months, 16 IPD had reverted to normoglycemia and 18 progressed to diabetes. TNFα -238AA/GA genotypes were significantly more common in IPD, had higher TNFα, higher progression to diabetes and lower reversal.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Dutta D,Choudhuri S,Mondal SA,Maisnam I,Reza AH,Ghosh S,Chowdhury S,Bhattacharya B,Mukhopadhyay S

doi

10.1016/j.diabres.2012.12.007

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

e37-41

issue

3

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(12)00505-0

journal_volume

99

pub_type

杂志文章

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