The changes of serum sKlotho and NGAL levels and their correlation in type 2 diabetes mellitus patients with different stages of urinary albumin.

abstract：AIMS:Insulin degludec/insulin aspart (IDegAsp) is a soluble co-formulation of IDeg and IAsp. This pan-Asian, 26-week trial investigated efficacy and safety of IDegAsp vs biphasic insulin aspart 30 (BIAsp 30) in Asian adults with type 2 diabetes (T2DM), inadequately controlled on once- or twice-daily (BID) basal, premix...

journal_title：Diabetes research and clinical practice

authors： Kaneko S,Chow F,Choi DS,Taneda S,Hirao K,Park Y,Andersen TH,Gall MA,Christiansen JS,BOOST: Intensify All Trial Investigators.

更新日期：2015-01-01 00:00:00

abstract：:Apoptosis and its associated regulatory mechanisms are physiological events crucial to the maintenance of placental homeostasis; imbalance of these processes, however, such as occurs under various pathological conditions, may compromise placenta function and, consequently, pregnancy success. Increased apoptosis occurs...

journal_title：Diabetes research and clinical practice

authors： Sgarbosa F,Barbisan LF,Brasil MA,Costa E,Calderon IM,Gonçalves CR,Bevilacqua E,Rudge MV

更新日期：2006-08-01 00:00:00

abstract：INTRODUCTION:Diabetes is a serious and increasing global health burden and estimates of prevalence are essential for appropriate allocation of resources and monitoring of trends. METHODS:We conducted a literature search of studies reporting the age-specific prevalence for diabetes and used the Analytic Hierarchy Proce...

journal_title：Diabetes research and clinical practice

authors： Guariguata L,Whiting DR,Hambleton I,Beagley J,Linnenkamp U,Shaw JE

更新日期：2014-02-01 00:00:00

abstract：AIMS:This study evaluates the effectiveness of three metabolic syndrome (MS) criteria in identifying cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) in the Chinese population. METHODS:3598 subjects were recruited from a cohort study on Prevention of Multiple Metabolic disorders and MS in Jiangsu of Ch...

journal_title：Diabetes research and clinical practice

authors： Zhou H,Guo ZR,Yu LG,Hu XS,Xu BH,Liu HB,Wu M,Zhou ZY

更新日期：2010-12-01 00:00:00

abstract：AIM:Studies on the effect of Ramadan diurnal intermittent fasting (RDIF) on glucometabolic markers have yielded conflicting results. We conducted ameta-analysis to estimate the effect size for changes in glucometabolic markers in healthy, non-athletic Muslims during Ramadan, and to assess the effect of variable covaria...

journal_title：Diabetes research and clinical practice

authors： Faris MA,Jahrami H,BaHammam A,Kalaji Z,Madkour M,Hassanein M

更新日期：2020-07-01 00:00:00

abstract：:The impact of several environmental and genetic factors on diabetes and its complications is well documented. The present study was aimed to examine the serum levels of IL-17A and IFN-gamma as antagonistic cytokines in nephropathic and non-nephropathic type-2 diabetic patients. In this experimental study, serum sample...

journal_title：Diabetes research and clinical practice

authors： Arababadi MK,Nosratabadi R,Hassanshahi G,Yaghini N,Pooladvand V,Shamsizadeh A,Hakimi H,Derakhshan R

更新日期：2010-01-01 00:00:00

abstract：:To determine the status of diabetes care by general practitioners and diabetes specialists in Japan, we conducted a nation-wide cross-sectional survey. We asked 8112 clinics and hospitals randomly, from throughout Japan, to participate in this study and 721 facilities agreed. A total of 15,652 patients aged from 15 to...

journal_title：Diabetes research and clinical practice

authors： Arai K,Hirao K,Matsuba I,Takai M,Matoba K,Takeda H,Kanamori A,Yamauchi M,Mori H,Terauchi Y

更新日期：2009-03-01 00:00:00

abstract：:The aim of this multicentre study was to investigate the effect--in everyday life--of long term administration of acarbose on parameters of glycaemic control, daily insulin requirements, lipid parameters and tolerability in ambulant type 1 diabetic subjects insufficiently controlled with diet and insulin. Furthermore,...

journal_title：Diabetes research and clinical practice

authors： Sels JP,Verdonk HE,Wolffenbuttel BH

更新日期：1998-08-01 00:00:00

abstract：:Insulin-like growth factor-I (IGF-I) is implicated in the development, survival and maintenance of function of sympathetic and sensory neurons. These neurons are affected at an early stage during the course of diabetes. Reverse transcriptase polymerase chain reaction (RT-PCR) based assay revealed that rat superior cer...

journal_title：Diabetes research and clinical practice

authors： Bitar MS,Pilcher CW,Khan I,Waldbillig RJ

更新日期：1997-11-01 00:00:00

abstract：:Moderate-to-vigorous physical activity (MVPA) has been shown to be inversely associated with C-reactive protein (CRP); however, the association between light intensity physical activity (LPA), and CRP is unknown. Our findings suggest that focusing on increasing MVPA, relative to LPA, may have a greater impact on infla...

journal_title：Diabetes research and clinical practice

authors： Hawkins M,Belalcazar LM,Schelbert KB,Richardson C,Ballantyne CM,Kriska A

更新日期：2012-07-01 00:00:00

abstract：:Dietary cod-liver oil containing eicosapentaenoic acid is effective on microvascular albumin leakage in diabetic patients with albuminuria. We determined the long-term effects of oral pure eicosapentaenoic acid ethyl (EPA-E: 900 mg/day) administration on diabetic nephropathy in non-insulin dependent diabetic (NIDDM) p...

journal_title：Diabetes research and clinical practice

authors： Shimizu H,Ohtani K,Tanaka Y,Sato N,Mori M,Shimomura Y

更新日期：1995-04-01 00:00:00

abstract：:Hypertension and Diabetes are the most common comorbid conditions in patients with COVID-19 and has been shown to adversely impact prognosis globally. It has been shown that hyperglycemia is one of the factors that increases the risk of poor outcomes in these patients. These patients are usually on multiple medication...

journal_title：Diabetes research and clinical practice

authors： Dalan R

更新日期：2020-06-01 00:00:00

abstract：AIMS:Type1 diabetes is generally regarded as an abruptly presenting disease in children without family history. The incidence and prevalence of insulin requiring diabetes in adults is unclear. The aim of this study was to clarify this issue by examining the epidemiology of type 1 diabetes diagnosed in adulthood in a co...

journal_title：Diabetes research and clinical practice

authors： Thordardottir TH,Hreidarsson AB,Benediktsson R

更新日期：2019-05-01 00:00:00

abstract：:Beyond improvement of glucose control, thiazolidinediones exert pleiotropic effects, which may contribute to some cardiovascular protection. PROactive ("PROspective pioglitAzone Clinical Trial In macroVascular Events") has provided valuable, although controversial, information on the impact of pioglitazone on cardiova...

journal_title：Diabetes research and clinical practice

authors： Scheen AJ

更新日期：2012-11-01 00:00:00

abstract：:There is evidence to suggest that hyperglycemia is required for the development of the microvascular complications of diabetes. However, the precise mechanism by which hyperglycemia might cause diabetic complications is not completely clear. One possibility is the increased activity of the polyol pathway. Capillary ba...

journal_title：Diabetes research and clinical practice

authors： Ramirez LC,Arauz C,Pruneda L,Hammon K,Rosenstock J,Raskin P

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:Several genome-wide association studies and replication analyses have identified common variation at the insulin-like binding protein 2 (IGF2BP2) gene to be associated with type 2 diabetes (T2DM). The aim of this study was to replicate in a Lebanese Arab population identified associations of IGF2BP2 variants ...

journal_title：Diabetes research and clinical practice

authors： Nemr R,Echtay A,Dashti EA,Almawi AW,Al-Busaidi AS,Keleshian SH,Irani-Hakime N,Almawi WY

更新日期：2012-05-01 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is a transient metabolic disorder that is a strong predictor of type 2 diabetes and cardiovascular disease. Previously, GDM was associated with reduced red cell long-chain omega-6 and omega-3 fatty acids in population (British) with high intake of total and saturated fat. The aim of...

journal_title：Diabetes research and clinical practice

authors： Min Y,Nam JH,Ghebremeskel K,Kim A,Crawford M

更新日期：2006-08-01 00:00:00

abstract：:Despite numerous publications according to which insulin promotes atherosclerosis, there are many observations in the last fifteen years suggesting that insulin has antiatherogenic properties. Insulin has vasodilatory, antithrombotic and anti-inflammatory effects. A good glycemic control contributes to the maximum eff...

journal_title：Diabetes research and clinical practice

authors： Karamitsos DT

更新日期：2011-08-01 00:00:00

abstract：:Rye flakes, rye bread and white wheat bread were given as suspensions to rats and in standardized breakfast meals to non-insulin-dependent diabetics. In both cases the postprandial glucose response was lower after rye bread than after wheat bread. A larger amount of starch remained in the stomach of the rats 15 min af...

journal_title：Diabetes research and clinical practice

authors： Hagander B,Björck I,Asp NG,Efendić S,Holm J,Nilsson-Ehle P,Lundquist I,Scherstén B

更新日期：1987-03-01 00:00:00

abstract：AIMS:The aim of the study was to determine physicians' knowledge of specific concepts generally implicated in the pathophysiology of type 2 diabetes (T2D). METHODS:A multiple choice online survey was completed by 847 physicians, of which 516 were engaged in primary care (PCP) and 331 in specialized care (SCP) in the U...

journal_title：Diabetes research and clinical practice

authors： Busse FP,Denti V,Stumvoll M

更新日期：2007-06-01 00:00:00

abstract：:Insulin's indispensible nature is recognised by its inclusion in the World Health Organization's Essential Medicines List. Despite this insulin is still not available on an uninterrupted basis in many parts of the developing world. The International Insulin Foundation has conducted in-country assessments and based on ...

journal_title：Diabetes research and clinical practice

authors： Beran D,Yudkin JS

更新日期：2010-06-01 00:00:00

abstract：AIM:Dyslipidaemia may be a risk factor for diabetic kidney disease. We examined prospectively association between the use of statins and development of renal dysfunction in type 2 diabetes. METHODS:A consecutive cohort of 5264 diabetic patient recruited between 1996 and 2005 underwent detailed assessments. Renal dysfu...

journal_title：Diabetes research and clinical practice

authors： Luk AO,Yang X,Ma RC,Ng VW,Yu LW,Lau WW,Ozaki R,Chow FC,Kong AP,Tong PC,Chan JC,So W

更新日期：2010-06-01 00:00:00

abstract：AIMS:To assess the relationship between patient activation for self-management and admissions to hospital or attendances at emergency departments among people with diabetes, after controlling for other known associations. METHODS:Patients were randomly selected from Australia's National Diabetes Services Scheme and in...

journal_title：Diabetes research and clinical practice

authors： Begum N,Donald M,Ozolins IZ,Dower J

更新日期：2011-08-01 00:00:00

abstract：:Insulin administration causes various types of immune response to insulin. However, there have been no reports that insulin administration triggers pancreatic beta-cell destruction in diabetic patients. We evaluated three patients who had suffered from type 2 diabetes or impaired glucose tolerance for 5-30 years. Afte...

journal_title：Diabetes research and clinical practice

authors： Nakamura M,Nishida W,Yamada Y,Chujo D,Watanabe Y,Imagawa A,Hanafusa T,Kawasaki E,Onuma H,Osawa H,Makino H

更新日期：2008-02-01 00:00:00

abstract：:Insulin (immunoreactive insulin, IRI) response during a 100 g oral glucose tolerance test was studied in a large number of patients with definite diabetes, equivocal diabetes, and other pathological states causing glucose intolerance. Definite diabetes was diagnosed in patients with overt fasting hyperglycemia. Once t...

journal_title：Diabetes research and clinical practice

authors： Kosaka K,Kuzuya T,Hagura R

更新日期：1994-10-01 00:00:00

abstract：:C57BL/KsJ mice carrying homozygous db/db mutation (db/db mice) are characterized by extreme obesity and early onset of hyperglycemia. In an attempt to rectify diabetes of these mice, a pancreatic beta cell line MIN6, which retains glucose-inducible insulin secretion, was transplanted subcutaneously into the back of th...

journal_title：Diabetes research and clinical practice

authors： Inada S,Kaneko S,Suzuki K,Miyazaki J,Asakura H,Fujiwara M

更新日期：1996-05-01 00:00:00

abstract：:In the present study, we recruited 124 patients with type 2 diabetes, among which 22 had a history of cardiovascular disease (CVD). The study demonstrated that compared with type 2 diabetes without CVD, those with CVD had remarkably higher levels of angiopoietin-like protein 8 (ANGPTL8). Moreover, the close relationsh...

journal_title：Diabetes research and clinical practice

authors： Huang Y,Fang C,Guo H,Hu J

更新日期：2016-10-01 00:00:00

abstract：:Mortality, macroangiopathic events and end-stage renal disease (ESRD) in the elderly under long-term, intensive multifactorial diabetes control were prospectively investigated. Three hundred and eighty-eight elderly patients (> or =65 years) with type 2 diabetes (the mean age 72.9 years, men/women ratio 176/212) were ...

journal_title：Diabetes research and clinical practice

authors： Katakura M,Naka M,Kondo T,Komatsu M,Yamauchi K,Hashizume K,Aizawa T,Nagano Elderly Diabetes Study Group.

更新日期：2007-10-01 00:00:00

abstract：:Gliclazide has been reported to possess the properties of preventing the progression of diabetic retinopathy and of controlling blood glucose levels. This report describes a long-term comparative clinical trial of this agent to assess its efficacy against diabetic retinopathy. One hundred and fifty-nine NIDDM patients...

journal_title：Diabetes research and clinical practice

authors： Akanuma Y,Kosaka K,Kanazawa Y,Kasuga M,Fukuda M,Aoki S

更新日期：1988-07-13 00:00:00

abstract：:The purpose of this study was to investigate the effect of both a single dose and daily oral administration for 15 days of the aqueous extract of the aerial part of Chamaemelum nobile (C. nobile) at a dose of 20mg/kg body weight on blood glucose concentrations and basal insulin levels in normal and streptozotocin-indu...

journal_title：Diabetes research and clinical practice

authors： Eddouks M,Lemhadri A,Zeggwagh NA,Michel JB

更新日期：2005-03-01 00:00:00