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Comparison of National Diabetes Data Group and American Diabetes Association diagnostic criteria for gestational diabetes in their identification of postpartum risk of glucose intolerance.

Abstract：

AIMS:Gestational diabetes mellitus (GDM) is associated with adverse obstetrical outcomes and postpartum pre-diabetes/diabetes. As the American Diabetes Association (ADA) criteria for GDM may capture obstetrical risk better than the National Diabetes Data Group (NDDG) criteria, we compared these criteria in their detection of postpartum risk of glucose intolerance. METHODS:487 Women underwent oral glucose tolerance test in pregnancy and at 3-month postpartum. Participants were stratified into the following 5 groups: normal glucose tolerance (NGT) by both ADA and NDDG; gestational impaired glucose tolerance (GIGT) by ADA only; GIGT by both ADA and NDDG; GDM by ADA only; and GDM by both ADA and NDDG. RESULTS:The prevalence of postpartum glucose intolerance (pre-diabetes/diabetes) varied across the groups (NGT by both ADA and NDDG: 5.9%; GIGT by ADA only: 14.3%; GIGT by both ADA and NDDG: 10.6%; GDM by ADA only: 21.6%; GDM by both ADA and NDDG: 32.8%; overall p<0.0001). Importantly, however, for predicting postpartum pre-diabetes/diabetes, abnormal antepartum glucose tolerance by NDDG and ADA, respectively, exhibited comparable positive predictive value (26% vs. 24%) and area-under-the-receiver-operating-characteristic-curve (0.67 vs. 0.66, p=0.63). CONCLUSIONS:Unlike with obstetrical outcomes, NDDG and ADA criteria for GDM are similar in their ability to identify postpartum metabolic risk.

journal_name

Diabetes Res Clin Pract

journal_title

Diabetes research and clinical practice

authors

Retnakaran R,Qi Y,Sermer M,Connelly PW,Zinman B,Hanley AJ

doi

10.1016/j.diabres.2009.04.008

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

40-6

issue

1

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(09)00156-9

journal_volume

85

pub_type

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