Diagnostic yield from 231 autopsies in a community hospital.

abstract：:Elevated T-cell leukemia-1 (TCL1) oncoprotein expression might promote human Burkitt lymphoma (BL) because increased TCL1 causes Burkitt-like lymphomas in TCL1 transgenic mice. Epstein-Barr virus (EBV) infection has been implicated as a cause of increased TCL1 expression in multiple BL cell lines, suggesting a critica...

journal_title：American journal of clinical pathology

authors： Teitell MA,Lones MA,Perkins SL,Sanger WG,Cairo MS,Said JW

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:To compare next-generation sequencing (NGS) platforms with mutation-specific analysis platforms in a clinical setting, in terms of sensitivity, mutation specificity, costs, capacity, and ease of use. METHODS:We analyzed 25 formalin-fixed, paraffin-embedded lung cancer samples of different size and tumor per...

journal_title：American journal of clinical pathology

authors： Hinrichs JW,van Blokland WT,Moons MJ,Radersma RD,Radersma-van Loon JH,de Voijs CM,Rappel SB,Koudijs MJ,Besselink NJ,Willems SM,de Weger RA

更新日期：2015-04-01 00:00:00

abstract：:Several adulterants are used to mask tests for abused drugs in urine. Adulterants such as "Klear" and "Whizzies" contain potassium nitrite, and "Urine Luck" contains pyridinium chlorochromate (PCC). The presence of these adulterants cannot be detected by routine specimen integrity checks (pH, specific gravity, and tem...

journal_title：American journal of clinical pathology

authors： Dasgupta A,Wahed A,Wells A

更新日期：2002-02-01 00:00:00

abstract：:Results of a comparison of the diagnostic efficacy of percutaneous needle biopsy of the parietal pleura with that of cytologic examination of pleural fluid sediment obtained concurrently from 166 patients with benign or cancerous pleural disorders are reported. Of 44 patients with confirmatory evidence of cancer invol...

journal_title：American journal of clinical pathology

authors： Frist B,Kahan AV,Koss LG

更新日期：1979-07-01 00:00:00

abstract：:This report describes the selective staining of lysosomes in cells of neutrophilic granulocytic origin by the azo textile dye basic blue 93. Used as a single agent aqueous stain after fixation, the dye stained lysosomes black. Stained in this way, lysosomes were sharply delimited and easily visualized. Large numbers o...

journal_title：American journal of clinical pathology

authors： Kass L

更新日期：1988-02-01 00:00:00

abstract：:The expression of bcl-2, CD10, and CD20 was examined by multicolor flow cytometry in 78 samples including lymph node or other tissue biopsy specimens containing follicular lymphoma (FL; n = 17), reactive hyperplasia (RH; n = 28), or other malignant lymphomas (n = 20), as well as bone marrow aspirates (n = 13). The pre...

journal_title：American journal of clinical pathology

authors： Cook JR,Craig FE,Swerdlow SH

更新日期：2003-01-01 00:00:00

abstract：:Immunohistochemical expression of napsin A in primary pulmonary mucinous tumors is not well established. Napsin A immunoreactivity was evaluated in 43 mucin-producing adenocarcinomas of the lung consisting of 18 tumors formerly classified as mucinous bronchioloalveolar carcinoma, 15 colloid adenocarcinomas, 5 solid pr...

journal_title：American journal of clinical pathology

authors： Wu J,Chu PG,Jiang Z,Lau SK

更新日期：2013-02-01 00:00:00

abstract：:Primary massive ovarian edema is uncommon, particularly when it involves both ovaries before puberty. Ovarian edema secondary to a preexisting ovarian lesion is one of the postulated mechanisms. A prepubertal girl presented with bilateral massive ovarian edema with stromal hyperthecosis, which may have predisposed bot...

journal_title：American journal of clinical pathology

authors： Lacson AG,Alrabeeah A,Gillis DA,Salisbury S,Grantmyre EB

更新日期：1989-05-01 00:00:00

abstract：:The API-20 Enteric Strip has been proposed to have the capacity to differentiate the nonfermentative gram-negative bacilli. This multitest strip serves as the basis of an evolving system, which first provided a Register, then a Selector, and more recently a computer Index. Twenty-three strains of Pseudomonas aeruginos...

journal_title：American journal of clinical pathology

authors： Morris MJ,Young VM,Moody MR

更新日期：1978-01-01 00:00:00

abstract：:A 28-month-old girl, whose parents are first cousins, was hospitalized following a series of severe infections. Results of functional granulocytic tests permitted the diagnosis of chronic granulomatous disease (lack of nitroblue tetrazolium dye reduction, impaired bactericidal activity for Staphylococcus aureus but no...

journal_title：American journal of clinical pathology

authors： Corberand J,De Larrard B,Vergnes H,Carrière JP

更新日期：1978-08-01 00:00:00

abstract：:Our aim was to study the possible association between oral lichen planus and chronic hepatitis C in patients from the state of Minas Gerais, Brazil. Two groups of patients were studied: group 1, 50 patients with oral lichen planus evaluated for the presence of chronic hepatitis C; and group 2, 215 patients with chroni...

journal_title：American journal of clinical pathology

authors： de Mattos Camargo Grossmann S,de Aguiar MC,Teixeira R,do Carmo MA

更新日期：2007-05-01 00:00:00

abstract：:The concept of re-engineering rests on computer coordination of information. As a management tool, it has been tested and found to be ambiguous. At best it sharpens laboratory objectives, but at worst it fragments skills and threatens the community attitudes needed for teamwork. Experience with its most fruitful compo...

journal_title：American journal of clinical pathology

authors： Lincoln TL

更新日期：1996-04-01 00:00:00

abstract：:Eight cases are reported of an unusual breast lesion consisting of dense intralobular, perilobular, and perivascular lymphocytic infiltrates associated with lobular atrophy and sclerosis. Immunologic studies on paraffin-embedded tissue (seven cases) and frozen tissue (two cases) demonstrated a predominance of B-cells ...

journal_title：American journal of clinical pathology

authors： Schwartz IS,Strauchen JA

更新日期：1990-06-01 00:00:00

abstract：:Immunohistochemical techniques applied to fresh frozen sections of metastatic malignant melanoma tissue revealed abundant fibrinogen (or fibrin I) in perivascular areas throughout the tumor connective tissue stroma. Fibrin was readily detected in a focal distribution in the connective tissue around nodules of viable t...

journal_title：American journal of clinical pathology

authors： Wojtukiewicz MZ,Zacharski LR,Memoli VA,Kisiel W,Kudryk BJ,Rousseau SM,Stump DC

更新日期：1990-04-01 00:00:00

abstract：Objectives:The plasma-thrombin method is commonly used to make cell blocks from fine-needle aspiration (FNA) samples but requires centrifugation. We describe a modification to this method that does not require centrifugation for use in resource-limited settings. Methods:Pooled fresh plasma is aliquoted into 2-mL Eppen...

journal_title：American journal of clinical pathology

authors： Aisagbonhi O,Birungi A,Atwine R,Behayo P,Ayebaziwe B,Roberts D,Tambouret R

更新日期：2018-07-03 00:00:00

abstract：OBJECTIVES:To describe our experience, both in meeting challenges and in reporting outcomes, of the consolidation of anatomic pathology services in the North Shore-LIJ Health System in February 2011. METHODS:We addressed issues of governance, personnel, physical plant, quality programming, connectivity, and education....

journal_title：American journal of clinical pathology

authors： Groppi DE,Alexis CE,Sugrue CF,Bevis CC,Bhuiya TA,Crawford JM

更新日期：2013-07-01 00:00:00

abstract：:A number of genetic abnormalities have been detected in multiple myeloma (MM) using cytogenetic techniques. The prominent abnormalities are deletions of 13q and translocations affecting the IgH locus on 14q32. The recurrence of chromosomal abnormalities in MM suggests a specific role for them concerning its pathogenes...

journal_title：American journal of clinical pathology

authors： Tchinda J,Volpert S,Kropff M,Berdel WE,Kienast J,Meinhardt F,Horst J

更新日期：2004-12-01 00:00:00

abstract：:Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thromb...

journal_title：American journal of clinical pathology

authors： Budman DR,Lackner H,Berczeller P,Silber R

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVES:Blood component waste is an important issue at all hospitals. As an initiative of the patient blood management program at a regional health care system, the causes and extent of blood product wastage were identified, and targeted interventions to effect a reduction were implemented. METHODS:Multiple low-cos...

journal_title：American journal of clinical pathology

authors： Collins RA,Wisniewski MK,Waters JH,Triulzi DJ,Yazer MH

更新日期：2015-03-01 00:00:00

abstract：:In a computerized case registry, containing 220 cases of sinus histiocytosis with massive lymphadenopathy (SHML), 23 patients were identified with clinical or routine laboratory findings suggestive or diagnostic of immune dysfunction. We divided the abnormalities into hematologic autoantibodies (nine patients), glomer...

journal_title：American journal of clinical pathology

authors： Foucar E,Rosai J,Dorfman RF,Eyman JM

更新日期：1984-11-01 00:00:00

abstract：Objectives:Early and accurate diagnosis remains crucial in the therapeutic management of invasive central nervous system fungal infections. Different molds have intrinsic resistance to antifungal agents; thus, morphologic differentiation is helpful to clinicians. Methods:Using three examples, we present a guide on how...

journal_title：American journal of clinical pathology

authors： Chavez JA,Brat DJ,Hunter SB,Velazquez Vega J,Guarner J

更新日期：2018-01-29 00:00:00

abstract：:A very simple method of computer-assisted reporting of surgical pathology (including gross description, microscopic description, and diagnosis) has been developed. This method is based on a modification of the existing microbiology program and files in the comprehensive MedLab Company Pathlab computer system, with the...

journal_title：American journal of clinical pathology

authors： Davey PW,Vaughan KD

更新日期：1982-09-01 00:00:00

abstract：:The measurement of beta-thromboglobulin (BTG) and platelet lactic dehydrogenase (LDH) as markers for alpha-granule release and platelet lysis, respectively, has been reported to correlate with the amount of damage incurred during the preparation and storage of platelet concentrates. We compared the concentrations of t...

journal_title：American journal of clinical pathology

authors： Kalmin ND,Wilson MJ,Liles BA

更新日期：1983-06-01 00:00:00

abstract：:Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign lesion of the oral mucosa of an unclear pathogenesis. We analyzed the profile of the inflammatory infiltrate in 12 cases of TUGSE by using immunohistochemical analysis and polymerase chain reaction-based repertoire analysis to detect T- and B...

journal_title：American journal of clinical pathology

authors： Hirshberg A,Amariglio N,Akrish S,Yahalom R,Rosenbaum H,Okon E,Kaplan I

更新日期：2006-10-01 00:00:00

abstract：:A case of septicemia caused by Pseudomonas paucimobilis is reported. This represents the first definitive case of disease produced by this yellow-pigmented, nonfermentative bacillus. ...

journal_title：American journal of clinical pathology

authors： Slotnick IJ,Hall J,Sacks H

更新日期：1979-11-01 00:00:00

abstract：:The quality management program in the Division of Transfusion Medicine at our institution had evolved to the point that the program generally was perceived to be the sole responsibility of our Quality Unit (which was administratively independent of day-to-day operations). It became clear that this administrative model...

journal_title：American journal of clinical pathology

authors： Foss ML,Moore SB

更新日期：2005-10-01 00:00:00

abstract：Objectives:A report on the multicenter evaluation of the Bruker MALDI Biotyper CA System (MBT-CA; Bruker Daltonics, Billerica, MA) for the identification of clinically important bacteria and yeasts. Methods:In total, 4,399 isolates of medically important bacteria and yeasts were assessed in the MBT-CA. These included ...

journal_title：American journal of clinical pathology

authors： Wilson DA,Young S,Timm K,Novak-Weekley S,Marlowe EM,Madisen N,Lillie JL,Ledeboer NA,Smith R,Hyke J,Griego-Fullbright C,Jim P,Granato PA,Faron ML,Cumpio J,Buchan BW,Procop GW

更新日期：2017-06-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) is characterized by typical morphologic features and the CD5+, CD23-immunophenotype. However, some morphologically typical MCLs are CD23+. A t(11;14)(q13;q32) translocation is frequently found in MCL, leading to overexpression of cyclin D1. We studied the expression of cyclin D1 in 50 small ...

journal_title：American journal of clinical pathology

authors： Peghini PE,Fehr J

更新日期：2002-02-01 00:00:00

abstract：:The effect of blood transfusion on DNA profiles of an individual is a significant issue in the forensic context. In the present study, the effects of blood transfusion in 5 recipients were studied by performing restriction fragment length polymorphism and polymerase chain reaction HLA-DQA1 and Polymarker (LDLR, GYPA, ...

journal_title：American journal of clinical pathology

authors： Giroti RI,Biswas R,Mukherjee K

更新日期：2002-09-01 00:00:00

abstract：:This study sought to compare Multiplate impedance platelet aggregometry (IPA) with light transmission aggregometry (LTA) and the PFA-100 for determining the prevalence of residual platelet reactivity (RPR) by the Multiplate IPA in 297 patients with acute coronary syndrome receiving dual antiplatelet therapy. Aggregati...

journal_title：American journal of clinical pathology

authors： Paniccia R,Antonucci E,Maggini N,Romano E,Gori AM,Marcucci R,Prisco D,Abbate R

更新日期：2009-06-01 00:00:00