An argonaute protein directs nuclear Xrn2 function.

Abstract:

:Argonaute proteins are the mediators of small RNA-guided gene silencing pathways. In this issue, Couvillion and coworkers (Couvillion et al., 2012) found an unexpected function for a Tetrahymena Argonaute protein: It forms a complex with tRNA fragments and is required for nuclear Xrn2 localization and function.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Hasler D,Meister G

doi

10.1016/j.molcel.2012.11.015

subject

Has Abstract

pub_date

2012-11-30 00:00:00

pages

485-6

issue

4

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(12)00946-X

journal_volume

48

pub_type

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