当前位置： SCI文献检索 > HUMAN IMMUNOLOGY期刊下所有文献 > Mannose-binding lectin gene polymorphisms are not associated with susceptibility to severe early childhood caries.

Mannose-binding lectin gene polymorphisms are not associated with susceptibility to severe early childhood caries.

Abstract：

:Our purpose was to investigate a possible relationship between severe early childhood caries (S-ECC) and polymorphism of the mannose binding lectin gene and investigate the role of allele variant as a possible factor in the susceptibility to S-ECC. Sixty-two Chinese children with S-ECC and 68 caries-free control children were included in this study. Genomic DNA was extracted from buccal epithelial cells of each individual. The identification of MBL B allele was performed by restriction fragment length polymorphism using Ban I restriction enzyme. The frequency of MBL mutant genotype (GGC/GAC and GAC/GAC) was more frequent among children with S-ECC compared with control groups, but did not significantly differ between two groups (x(2) = 2.82, p > 0.05). There was no significant difference in the allele frequency of codon54 wild type (allele A) between two groups (x(2) = 2.76, p > 0.05). The present study did not find evidence of MBL codon54 polymorphisms being associated with S-ECC in the population studied, but a larger sample size is necessary to confirm the present results.

journal_name

Hum Immunol

journal_title

Human immunology

authors

Yang Y,Wang W,Qin M

doi

10.1016/j.humimm.2012.08.012

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

110-3

issue

1

eissn

0198-8859

issn

1879-1166

pii

S0198-8859(12)00538-1

journal_volume

74

pub_type

杂志文章

相关文献

HUMAN IMMUNOLOGY文献大全
  • NFAT-1, Sp-1, Sp-3, and miR-21: New regulators of chemokine C receptor 7 expression in mature human dendritic cells.

    abstract：:The chemokine C receptor 7 (CCR7) is a G-protein-coupled heptahelical receptor (GPCR) that is expressed on a wide variety of cells including memory T cells, B cells, mature dendritic cells, and cancer cells. Activated by its ligands CCL19 or CCL21, CCR7 plays a major role in metastasis of cancer cells. Recent studies ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2015.03.010

    authors： Al Akoum C,Akl I,Rouas R,Fayyad-Kazan M,Falha L,Renno T,Burny A,Lewalle P,Fayyad-Kazan H,Badran B

    更新日期：2015-05-01 00:00:00

  • Serologic recognition of a HLA-B44(12) subgroup associated with the 44.2 specificity defined by CML.

    abstract：:Several investigators have reported that subdivisions of HLA-B44, which are not defined by available cytotoxic antisera, can be detected by cytotoxic T lymphocytes. The present study was designed to evaluate two sera which appear to recognize a specificity on some HLA-B44 and B45 positive cells and to determine whethe...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(84)90073-9

    authors： Heise ER,Tekolf WA,Hampton JP

    更新日期：1984-11-01 00:00:00

  • Effects of age, gender, and immunosuppressive agents on in vivo toll-like receptor pathway responses.

    abstract：:Toll-like receptors (TLRs) are important in the initiation of immune responses in both health and disease. How TLR activity alters with age, gender, and also with immunosuppressive agents is still largely unexplored. We studied TLR activity in 49 healthy individuals as well as in 26 patients receiving immunosuppressiv...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2010.01.018

    authors： Khan N,Summers CW,Helbert MR,Arkwright PD

    更新日期：2010-04-01 00:00:00

  • Increased expressions of CD69 and HLA-DR but not of CD25 or CD71 on endometrial T lymphocytes of nonpregnant women.

    abstract：:To investigate lymphocyte subpopulations and the status of T-cell activation at different phases of the menstrual cycle, lymphocytes in endometrial tissue were analyzed by dual-color flow cytometry in 39 patients. Compared with peripheral blood, the lymphocytes in the endometrium had a higher CD3-/(CD56+ or CD16+) rat...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(94)00105-y

    authors： Chen CK,Huang SC,Chen CL,Yen MR,Hsu HC,Ho HN

    更新日期：1995-03-01 00:00:00

  • MHC haplotype analysis by artificial neural networks.

    abstract：:Conventional matching is based on numbers of alleles shared between donor and recipient. This approach, however, ignores the degree of relationship between alleles and haplotypes, and therefore the actual degree of difference. To address this problem, we have compared family members using a block matching technique wh...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(97)00231-0

    authors： Bellgard MI,Tay GK,Hiew HL,Witt CS,Ketheesan N,Christiansen FT,Dawkins RL

    更新日期：1998-01-01 00:00:00

  • T-cell receptor bias in patients with allergic bronchopulmonary aspergillosis.

    abstract：:CD4(+) Th2 helper cell mediated immune responses have been shown to play a crucial role in the pathogenesis of ABPA. HLA and TCR are the candidate genes, which can influence the specificity of these responses. We have previously established a strong association of HLA DR2/5 in ABPA susceptibility. The study was design...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(02)00361-0

    authors： Chauhan B,Hutcheson PS,Slavin RG,Bellone CJ

    更新日期：2002-04-01 00:00:00

  • CTLA4 and CD86 gene polymorphisms and susceptibility to chronic obstructive pulmonary disease.

    abstract：:Chronic obstructive pulmonary disease (COPD) may be related to chronic inflammation and immune-mediated conditions, and its pathogenesis involves T-cell activation and proliferation. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and costimulatory molecules (CD80/CD86) genes are important mediators of T-cell act...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2010.08.007

    authors： Liu Y,Liang WB,Gao LB,Pan XM,Chen TY,Wang YY,Xue H,Zhang LS,Zhang L

    更新日期：2010-11-01 00:00:00

  • A blueprint for electronic utilization of ambiguous molecular HLA typing data in organ allocation systems and virtual crossmatch.

    abstract：:Virtual crossmatch (VXM) compares a transplant candidate's unacceptable antigens to the HLA typing of the donor before an organ offer is accepted and, in selected cases, supplant a prospective physical crossmatch. However, deceased donor typing can be ambiguous, leading to uncertainty in compatibility prediction. We h...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2020.01.007

    authors： Kaur N,Pinelli D,Kransdorf EP,Pando MJ,Smith G,Murphey CL,Kamoun M,Bray RA,Tambur A,Gragert L

    更新日期：2020-01-01 00:00:00

  • Human HLA-DQ beta chain presents minor lymphocyte stimulating locus gene products and clonally deletes TCR V beta 6+, V beta 8.1+ T cells in single transgenic mice.

    abstract：:Minor lymphocyte stimulating locus (Mls) gene products in association with mouse major histocompatibility complex (MHC) class II molecules are known to determine the repertoire of T-cell receptor (TCR) in mature T cells. In order to test whether human class II molecules can present mouse Mls, HLA-DQ beta transgenic mi...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(91)90048-e

    authors： Zhou P,Anderson GD,Savarirayan S,Inoko H,David CS

    更新日期：1991-05-01 00:00:00

  • Characterization of T-cell-receptor gamma (TRG) gene rearrangements in alloreactive T-cell clones.

    abstract：:Rearrangements of the T-cell Rearranging Gene (TRG) or T-cell-receptor gamma-chain genes were analyzed in 24 in vivo-sensitized alloreactive T-cell clones. This analysis represents the first complete assignment of TRG gene rearrangements to given variable and joining gene segments in nonleukemic T cells and provides s...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(89)90050-5

    authors： Moisan JP,Bonneville M,Bouyge I,Moreau JF,Soulillou JP,Lefranc MP

    更新日期：1989-02-01 00:00:00

  • Genetic diversity of HLA system in four populations from Baja California, Mexico: Mexicali, La Paz, Tijuana and rural Baja California.

    abstract：:We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 250 Mexicans from the states of Baja California Norte and Baja California Sur living in Mexicali (N = 100), La Paz (N = 75), Tijuana (N = 25) and rural communities (N = 50) to obtain information regarding allelic and h...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2019.06.007

    authors： Escobedo-Ruíz A,Barquera R,González-Martín A,Argüelles-San Millán JM,Uribe-Duarte MG,Hernández-Zaragoza DI,Clayton S,Arrieta-Bolaños E,Ruíz-Corral MJ,Goné-Vázquez I,Arellano-Prado FP,Martínez-Álvarez JC,García-Arias VE,Rodrígue

    更新日期：2020-09-01 00:00:00

  • Tolerance: a case of self/not-self discrimination maintained by clonal deletion?

    abstract：:The clonal selection theory of immune reactivity is based on a metaphor of self/not-self discrimination and considers self-tolerance to result from clonal deletion. There is evidence that a deletional mechanism is responsible for negative selection of self MHC-reactive T-cells in the thymus. Bretscher/Cohn theory buil...

    journal_title：Human immunology

    pub_type： 历史文章,杂志文章,评审

    doi：10.1016/S0198-8859(96)00294-7

    authors： Lafferty KJ,Gazda LS

    更新日期：1997-02-01 00:00:00

  • Infection with a virus generates a polyclonal immune response with broad alloreactive potential.

    abstract：:Virus-specific T cells have been shown to cross-react with allogeneic HLA (allo-HLA) at a clonal level. However, the impact of a single virus on the allorepertoire has never been investigated at the polyclonal level. We made an inventory of the incidence and specificity of allo-HLA-cross-reactive-virus-specific CD8+ T...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2018.10.014

    authors： van den Heuvel H,van der Meer-Prins EMW,van Miert PPMC,Zhang X,Anholts JDH,Claas FHJ

    更新日期：2019-02-01 00:00:00

  • Overlap between molecular markers expressed by naturally occurring CD4+CD25+ regulatory T cells and antigen specific CD4+CD25+ and CD8+CD28- T suppressor cells.

    abstract：:Alloantigen specific CD8+CD28- T suppressor (TS) cells differ from naturally occurring CD4+CD25+ T-regulatory (natural TR) cells not only by their phenotype but also by their mechanism of action. Natural TR have been extensively studied, leading to the identification of characteristic "molecular markers" such as Forkh...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2004.09.004

    authors： Scotto L,Naiyer AJ,Galluzzo S,Rossi P,Manavalan JS,Kim-Schulze S,Fang J,Favera RD,Cortesini R,Suciu-Foca N

    更新日期：2004-11-01 00:00:00

  • Restriction fragment length polymorphism in HLA class II genes of Latin-American Caucasian celiac disease patients.

    abstract：:In the present study Latin-American celiac disease patients were analyzed for the frequency of certain HLA class II restriction fragment length polymorphisms in order to investigate whether they exhibited the normal associated alleles or showed unusual class II variants. A DPB/RsaI 4.0-kb fragment that was shown to be...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(89)90005-0

    authors： Herrera M,Chertkoff L,Palavecino E,Mota A,Guala MC,Fainboim L,Satz ML

    更新日期：1989-12-01 00:00:00

  • Analysis of the adequate size of a cord blood bank and comparison of HLA haplotype distributions between four populations.

    abstract：:The number of units and especially the number of different HLA haplotypes present in a cord blood (CB) bank is a crucial determinant of its usefulness. We generated data relevant to the development of our national CB in Finland. The HLA haplotype distribution was examined between specific populations. We developed gra...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2012.10.018

    authors： Haimila K,Penttilä A,Arvola A,Auvinen MK,Korhonen M

    更新日期：2013-02-01 00:00:00

  • Interferon-gamma response region in the promoter of the class II MHC gene, DPA.

    abstract：:The class II MHC gene DPA is inducible by interferon-gamma (IFN-gamma), whereas the DQB gene is not inducible in most cell types. To investigate the DNA region specifically responsible for inducibility or its lack that may be required (in addition to the elements required for constitutive expression of class II genes)...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(92)90100-2

    authors： Sugawara M,Ponath PD,Yang Z,Strominger JL

    更新日期：1992-11-01 00:00:00

  • Soluble HLA in human body fluids.

    abstract：:There is a growing body of information about the soluble forms of HLA in serum but there are only a few reports discussing sHLA in other body fluids. We quantitated sHLA-I and sHLA-II concentrations in sweat, saliva and tear samples from five normal individuals with known HLA-phenotypes. We also studied sweat samples ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(98)00122-0

    authors： Aultman D,Adamashvili I,Yaturu K,Langford M,Gelder F,Gautreaux M,Ghali GE,McDonald J

    更新日期：1999-03-01 00:00:00

  • Genetic susceptibility to multiple sclerosis: detection of polymorphic nucleotides and an intron in the 3' untranslated region of the major histocompatibility complex class II transactivator gene.

    abstract：:The master player in the transcriptional regulation of major histocompatibility (MHC) class II genes is a factor known as the MHC class II transactivator (CIITA). In this study we searched for polymorphisms in the 5' and 3' ends of the human CIITA gene to assess whether or not there is an association between alleles o...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(01)00215-4

    authors： Rasmussen HB,Kelly MA,Clausen J

    更新日期：2001-04-01 00:00:00

  • Human melanoma cell secreting human leukocyte antigen-G5 inhibit natural killer cell cytotoxicity by impairing lytic granules polarization toward target cell.

    abstract：:Human leukocyte antigen-G (HLA-G) is a nonclassical tolerogenic molecule that can be expressed either as membrane bound (HLA-G1) or secreted (HLA-G5) isoforms. Upregulation of HLA-G1 or HLA-G5 expression by tumor cells constitutes an efficient way to escape from antitumoral immune responses. The inhibitory role of HLA...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2009.07.019

    authors： Lesport E,Baudhuin J,LeMaoult J,Sousa S,Doliger C,Carosella ED,Favier B

    更新日期：2009-12-01 00:00:00

  • Analysis of HLA-DQ molecules with a monoclonal antibody detecting a DQ polymorphism absent from DQW1 homozygous cells.

    abstract：:We have produced a monoclonal antibody detecting an HLA class II determinant absent from DR1,2,W6, and W10 (DQW1) homozygous B lymphoblastoid cell lines (BLCL). The antibody, SFR16-PI.2, immunoprecipitates molecules with electrophoretic mobilities of DQ (DS/DC) molecules from DR7 homozygous cell lines. SFR16-PI.2 bind...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(85)90229-0

    authors： Radka SF,Stewart SJ,Smith SA

    更新日期：1985-11-01 00:00:00

  • Penaeus monodon tropomyosin induces CD4 T-cell proliferation in shrimp-allergic patients.

    abstract：:Shellfish allergy affects approximately 2% of the population and can cause immediate hypersensitivity reactions such as urticaria, swelling, difficulty breathing, and, in some cases, anaphylaxis. Tropomyosin is the major shrimp allergen and binds IgE in two-thirds of patients. A total of 38 shrimp-allergic patients an...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2011.12.019

    authors： Wang S,Delgado JC,Ravkov E,Eckels DD,Georgelas A,Pavlov IY,Cusick M,Sebastian K,Gleich GJ,Wagner LA

    更新日期：2012-04-01 00:00:00

  • Interleukin 6 -174G>C polymorphism and cancer risk: meta-analysis reveals a site dependent differential influence in Ancestral North Indians.

    abstract：:In our earlier studies, single nucleotide polymorphisms (SNPs) associated with anti-inflammatory cytokines were found to influence risk for breast cancer in western Indian women. Analysis of Interleukin 6 (IL-6) -174G>C polymorphism in this cohort (patients = 182; controls = 236) suggested a protective role for IL-6 -...

    journal_title：Human immunology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.humimm.2014.06.018

    authors： Joshi N,Kannan S,Kotian N,Bhat S,Kale M,Hake S

    更新日期：2014-08-01 00:00:00

  • MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ.

    abstract：:To ascertain association of MICA with type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients were analyzed for MICA transmembrane gene polymorphism in both an association study and a nuclear family study. The frequency of MICA5 was significantly increased in the T1D patient grou...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2006.02.032

    authors： Van Autreve JE,Koeleman BP,Quartier E,Aminkeng F,Weets I,Gorus FK,Van der Auwera BJ,Belgian Diabetes Registry.

    更新日期：2006-01-01 00:00:00

  • Genetic diversity of HLA system in a population from Guerrero, Mexico.

    abstract：:We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 144 Mexicans from the state of Guerrero to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in the state of Guerrero include eight Native American and two E...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2019.05.015

    authors： Juárez-Nicolás F,Barquera R,Martínez-Álvarez JC,Hernández-Zaragoza DI,Ortega-Yáñez A,Arrieta-Bolaños E,Clayton S,Bravo-Acevedo A,Arrazola-García MA,Immel A,Juárez-Barreto V,Benítez-Arvizu G,Vega-Martínez MDR,García-Álvarez R,

    更新日期：2020-09-01 00:00:00

  • Cell-mediated cytotoxicity and the reorientation of effector cell granules towards the target cell are inhibited by the protonophore carbonylcyanide m-chlorophenylhydrazone.

    abstract：:Cell-mediated cytotoxicity involves a localized secretory process in which lytic agents stored in specialized granules of the effector cells are released upon contact with the appropriate target cell membrane and cause membrane damage. The protonophore carbonylcyanide m-chlorophenylhydrazone (CCCP) inhibits cytotoxici...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(88)90039-0

    authors： McKinnon KP,Dunlevy JR,Dawson JR,Argon Y

    更新日期：1988-06-01 00:00:00

  • HLA-DQA1 allele and suballele typing using noncoding sequence polymorphisms. Application to 4AOHW cell panel typing.

    abstract：:HLA-DQA1 typing of the 4AOHW cell panel is presented using a novel strategy that exploits both intron and exon polymorphisms. Intron sequences adjacent to the variable HLA-DQA1 second exon exhibit stable polymorphisms that are specific for locus alleles and certain suballelic DR/DQ haplotypes. A PCR-RFLP method has be...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(93)90520-b

    authors： Limm TM,Ashdown ML,Naughton MJ,McGinnis MD,Simons MJ

    更新日期：1993-09-01 00:00:00

  • Polymorphism of the inducible nitric oxide synthase gene in celiac disease.

    abstract：:The aim of this study was to investigate the possible association between the inducible nitric oxide synthase (NOS2) gene promoter polymorphism, CCTTTn microsatellite, with celiac disease susceptibility. We carried out a familial study in which 53 Spanish families were genotyped by a polymerase chain reaction (PCR)-ba...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(02)00443-3

    authors： Rueda B,López-Nevot MA,Pascual M,Ortega E,Maldonado J,López ML,Koeleman BP,Martín J

    更新日期：2002-11-01 00:00:00

  • Severe pulmonary sarcoidosis is strongly associated with the haplotype HLA-DQB1*0602-DRB1*150101.

    abstract：:Sarcoidosis is a multiorgan granulomatous disease of unknown etiology. Several lines of evidence suggest a genetic predisposition and associations have been demonstrated with HLA antigens. HLA-DQB1 has been proposed as one of the candidate genes. To investigate the relationship between DQB1 and sarcoidosis at the alle...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2005.04.003

    authors： Voorter CE,Drent M,van den Berg-Loonen EM

    更新日期：2005-07-01 00:00:00

  • Differential expression of HLA-G and ILT-2 receptor in human tuberculosis: Localized versus disseminated disease.

    abstract：:Human leukocyte antigen-G (HLA-G) is an anti-inflammatory and immunosuppressive molecule that can modulate immune cell activation. The role of HLA-G in tuberculosis, an immune-mediated and chronic bacterial disease remains to be elucidated. We investigated the expression profile of soluble and membrane bound HLA-G in ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2016.01.004

    authors： Saurabh A,Thakral D,Mourya MK,Singh A,Mohan A,Bhatnagar AK,Mitra DK,Kanga U

    更新日期：2016-09-01 00:00:00