Workflow-centred evaluation of an automatic lesion tracking software for chemotherapy monitoring by CT.

Abstract:

OBJECTIVES:In chemotherapy monitoring, an estimation of the change in tumour size is an important criterion for the assessment of treatment success. This requires a comparison between corresponding lesions in the baseline and follow-up computed tomography (CT) examinations. We evaluate the clinical benefits of an automatic lesion tracking tool that identifies the target lesions in the follow-up CT study and pre-computes the lesion volumes. METHODS:Four radiologists performed volumetric follow-up examinations for 52 patients with and without lesion tracking. In total, 139 lung nodules, liver metastases and lymph nodes were given as target lesions. We measured reading time, inter-reader variability in lesion identification and volume measurements, and the amount of manual adjustments of the segmentation results. RESULTS:With lesion tracking, target lesion assessment time decreased by 38 % or 22 s per lesion. Relative volume difference between readers was reduced from 0.171 to 0.1. Segmentation quality was comparable with and without lesion tracking. CONCLUSIONS:Our automatic lesion tracking tool can make interpretation of follow-up CT examinations quicker and provide results that are less reader-dependent. KEY POINTS:Computed tomography is widely used to follow-up lesions in oncological patients. Novel software automatically identifies and measures target lesions in oncological follow-up examinations. This enables a reduction of target lesion assessment. The automated measurements are less reader-dependent.

journal_name

Eur Radiol

journal_title

European radiology

authors

Moltz JH,D'Anastasi M,Kiessling A,Pinto dos Santos D,Schülke C,Peitgen HO

doi

10.1007/s00330-012-2545-8

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

2759-67

issue

12

eissn

0938-7994

issn

1432-1084

journal_volume

22

pub_type

杂志文章
  • Effect of computer-aided detection as a second reader in multidetector-row CT colonography.

    abstract::Our purpose was to assess the effect of computer-aided detection (CAD) on lesion detection as a second reader in computed tomographic colonography, and to compare the influence of CAD on the performance of readers with different levels of expertise. Fifty-two CT colonography patient data-sets (37 patients: 55 endoscop...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-007-0608-z

    authors: Mang T,Peloschek P,Plank C,Maier A,Graser A,Weber M,Herold C,Bogoni L,Schima W

    更新日期:2007-10-01 00:00:00

  • Endorectal magnetic resonance imaging of prostatic cancer: comparison between fat-suppressed T2-weighted fast spin echo and three-dimensional dual-echo, steady-state sequences.

    abstract::The aim of this study was to develop an endorectal MRI strategy for prostatic cancer. We evaluated the MR images from 44 consecutive prostatic cancer patients treated by radical prostatectomy. Each sequence from every examination was assessed separately with a specific tumor map drawn. Tumor localization, capsular pen...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300000598

    authors: Ikonen S,Kärkkäinen P,Kivisaari L,Salo JO,Taari K,Vehmas T,Tervahartiala P,Rannikko S

    更新日期:2001-01-01 00:00:00

  • Dose reduction in skeletal and chest radiography using a large-area flat-panel detector based on amorphous silicon and thallium-doped cesium iodide: technical background, basic image quality parameters, and review of the literature.

    abstract::The two most frequently performed diagnostic X-ray examinations are those of the extremities and of the chest. Thus, dose reduction in the field of conventional skeletal and chest radiography is an important issue and there is a need to reduce man-made ionizing radiation. The large-area flat-panel detector based on am...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-004-2243-2

    authors: Völk M,Hamer OW,Feuerbach S,Strotzer M

    更新日期:2004-05-01 00:00:00

  • Quantitative MRI using STrategically Acquired Gradient Echo (STAGE): optimization for 1.5 T scanners and T1 relaxation map validation.

    abstract:OBJECTIVES:The strategically acquired gradient echo (STAGE) protocol, developed for 3T scanners, allows one to derive quantitative maps such as T1, T2*, proton density, and quantitative susceptibility mapping in about 5 min. Our aim was to adapt the STAGE sequences for 1.5T scanners which are still commonly used in cli...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07515-z

    authors: Pirastru A,Chen Y,Pelizzari L,Baglio F,Clerici M,Haacke EM,Laganà MM

    更新日期:2021-01-06 00:00:00

  • Neurilemoma of the renal capsule: MR imaging and pathologic correlation.

    abstract::We report a case of neurilemoma arising from the renal capsule. Renal neurilemoma is an especially rare tumor, with only 15 cases previously reported. We attempted to correlate MR findings with microscopic components of the tumor. On T2-weighted images the solid part of the tumor was heterogeneous hyperintense. The MR...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300000767

    authors: Tsurusaki M,Mimura F,Yasui N,Minayoshi K,Sugimura K

    更新日期:2001-01-01 00:00:00

  • Pulmonary aplasia: MR angiography findings.

    abstract::A 26-year-old woman presented with absence of the left lung. A diagnosis of pulmonary aplasia (main bronchus ending in a blind pouch) was established by bronchoscopy. Although a CT scan and MR imaging suggested the correct diagnosis, MR angiography enabled optimal demonstration of the vascular changes due to the anoma...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/BF00619968

    authors: Alper H,Sener RN

    更新日期:1996-01-01 00:00:00

  • Imaging features of spinal osteoid osteoma with emphasis on MRI findings.

    abstract::A retrospective evaluation of the imaging of 13 patients with a diagnosis of osteoid osteoma (OO) of the spine was undertaken. Available imaging included radiographs (n=10), computed tomography (CT) (n=13), bone scintigraphy (n=5) and magnetic resonance imaging (MRI) (n=13). MRI features evaluated were pattern of neur...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-005-2816-8

    authors: Harish S,Saifuddin A

    更新日期:2005-12-01 00:00:00

  • High-resolution CT of paediatric lung disease.

    abstract::High-resolution computed tomography (HRCT) has improved our understanding of many lung diseases in adults. The technique is used less often in children due to concerns regarding radiation dose. However, HRCT may provide important diagnostic information in a variety of lung diseases in children including airways diseas...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300100865

    authors: Copley SJ,Padley SP

    更新日期:2001-01-01 00:00:00

  • Short tau inversion recovery and proton density-weighted fat suppressed sequences for the evaluation of osteoarthritis of the knee with a 1.0 T dedicated extremity MRI: development of a time-efficient sequence protocol.

    abstract::Aim of this study was to develop a time-efficient sequence protocol for a 1.0 T dedicated MR system to be used for whole-organ scoring of osteoarthritis (OA). Thirty-four knees were examined using a protocol that included fat suppressed fast spin echo proton density weighted sequences (PDFS) in three planes plus a cor...

    journal_title:European radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00330-004-2608-6

    authors: Roemer FW,Guermazi A,Lynch JA,Peterfy CG,Nevitt MC,Webb N,Li J,Mohr A,Genant HK,Felson DT

    更新日期:2005-05-01 00:00:00

  • Nitroglycerine use in transcatheter arterial (chemo)embolization in patients with hepatocellular carcinoma and dual-energy CT assessment of Lipiodol retention.

    abstract:OBJECTIVES:To investigate whether the addition of nitroglycerine to transcatheter arterial (chemo)embolization (TAE/TACE) can increase the delivery and effectiveness of TAE/TACE in patients with hepatocellular carcinoma (HCC) by dual-energy CT. METHODS:HCC patients (BCLC stage A or B) were randomized to (n = 51) or no...

    journal_title:European radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00330-012-2484-4

    authors: Liu YS,Chuang MT,Tsai YS,Tsai HM,Lin XZ

    更新日期:2012-10-01 00:00:00

  • Native T1 mapping compared to ultrasound elastography for staging and monitoring liver fibrosis: an animal study of repeatability, reproducibility, and accuracy.

    abstract:OBJECTIVES:To investigate the repeatability, reproducibility, and staging and monitoring of the performance of native T1 mapping for noninvasively assessing liver fibrosis in comparison with acoustic radiation force impulse (ARFI) elastography. METHODS:The repeatability and reproducibility were explored in 8 male Spra...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-019-06335-0

    authors: Li J,Liu H,Zhang C,Yang S,Wang Y,Chen W,Li X,Wang D

    更新日期:2020-01-01 00:00:00

  • Automatic bolus tracking in monophasic spiral CT of the liver: liver-to-lesion conspicuity.

    abstract::The aim of this study was to evaluate the value of automatic bolus tracking for monophasic spiral CT of the liver and to assess the liver-to-lesion conspicuity in comparison with time-delay examinations. In 40 patients scheduled for therapy control of known hypovascular hepatic metastases a monophasic spiral CT was co...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300000637

    authors: Mehnert F,Pereira PL,Trübenbach J,Kopp AF,Claussen CD

    更新日期:2001-01-01 00:00:00

  • A new technique for noise reduction at coronary CT angiography with multi-phase data-averaging and non-rigid image registration.

    abstract:OBJECTIVES:To investigate the feasibility of a newly developed noise reduction technique at coronary CT angiography (CTA) that uses multi-phase data-averaging and non-rigid image registration. METHODS:Sixty-five patients underwent coronary CTA with prospective ECG-triggering. The range of the phase window was set at 7...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-014-3381-9

    authors: Tatsugami F,Higaki T,Nakamura Y,Yamagami T,Date S,Fujioka C,Kiguchi M,Kihara Y,Awai K

    更新日期:2015-01-01 00:00:00

  • Late aneurysm formation in a femoro-popliteal polytetrafluoroethylene graft.

    abstract::Since improvement in the material, true aneurysms and pseudoaneurysm formations have become relatively rare complications after femoro-popliteal reconstruction with polytetrafluoroethylene (PTFE) grafts. We report a case of late graft rupture and pseudoaneurysm formation within the straight femoral part of a femoro-po...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050909

    authors: Biederer J,Müller-Hülsbeck S,Loose JR,Heller M

    更新日期:1999-01-01 00:00:00

  • Comparing dual energy CT and subtraction CT on a phantom: which one provides the best contrast in iodine maps for sub-centimetre details?

    abstract:OBJECTIVES:To compare contrast-to-noise ratios (CNRs) and iodine discrimination thresholds on iodine maps derived from dual energy CT (DECT) and subtraction CT (SCT). METHODS:A contrast-detail phantom experiment was performed with 2 to 15 mm diameter tubes containing water or iodinated contrast concentrations ranging ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5496-x

    authors: Baerends E,Oostveen LJ,Smit CT,Das M,Sechopoulos I,Brink M,de Lange F,Prokop M

    更新日期:2018-12-01 00:00:00

  • Contrast-enhanced three-dimensional MR angiography in the assessment of subclavian artery diseases.

    abstract::The purpose of this prospective study was to determine the potential diagnostic value of 3D breath-hold contrast-enhanced MRA (CEMRA) in the evaluation of subclavian artery pathology, and to compare CEMRA and digital subtraction angiography (DSA) findings. The study group included 50 patients with suspicion of subclav...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300000454

    authors: Cosottini M,Zampa V,Petruzzi P,Ortori S,Cioni R,Bartolozzi C

    更新日期:2000-01-01 00:00:00

  • Staging of Klatskin tumours (hilar cholangiocarcinomas): comparison of MR cholangiography, MR imaging, and endoscopic retrograde cholangiography.

    abstract::The aim of the study was to compare prospectively magnetic resonance cholangiography (MRC) and magnetic resonance imaging (MRI) with endoscopic retrograde cholangiography (ERC) in the diagnosis and staging of Klatskin tumours of the biliary tree (hilar cholangiocarcinomas). Forty-six patients with suspected Klatskin t...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-005-0139-4

    authors: Vogl TJ,Schwarz WO,Heller M,Herzog C,Zangos S,Hintze RE,Neuhaus P,Hammerstingl RM

    更新日期:2006-10-01 00:00:00

  • MRI texture analysis of subchondral bone at the tibial plateau.

    abstract:OBJECTIVES:To determine the feasibility of MRI texture analysis as a method of quantifying subchondral bone architecture in knee osteoarthritis (OA). METHODS:Asymptomatic subjects aged 20-30 (group 1, n = 10), symptomatic patients aged 40-50 (group 2, n = 10) and patients scheduled for knee replacement aged 55-85 (gro...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-015-4142-0

    authors: MacKay JW,Murray PJ,Kasmai B,Johnson G,Donell ST,Toms AP

    更新日期:2016-09-01 00:00:00

  • Sports-related groin pain: evaluation with MR imaging.

    abstract::Our purpose was to assess the role of MRI in evaluating the musculoskeletal system in athletes with chronic pain laterally in the groin of unknown etiology. Magnetic resonance imaging (MRI) of the pubic ring was performed in 11 young athletes (soccer players) with long-standing groin pain. MR findings were compared wi...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/BF00619952

    authors: Ekberg O,Sjöberg S,Westlin N

    更新日期:1996-01-01 00:00:00

  • Ultrasound features of malignancy in the preoperative diagnosis of parathyroid cancer: a retrospective analysis of parathyroid tumours larger than 15 mm.

    abstract:OBJECTIVE:Nearly all reported parathyroid cancers are >15 mm at presentation. The objective was to identify ultrasound criteria of malignancy in parathyroid lesions of >15 mm in size. MATERIALS AND METHODS:This study was approved by a local ethics committee. A retrospective review of patients identified from a databas...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-011-2141-3

    authors: Sidhu PS,Talat N,Patel P,Mulholland NJ,Schulte KM

    更新日期:2011-09-01 00:00:00

  • MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent.

    abstract:OBJECTIVES:X-ray iodinated contrast media have been shown to generate contrast in MR images when used with the chemical exchange saturation transfer (CEST) approach. The aim of this study is to compare contrast enhancement (CE) capabilities and perfusion estimates between radiographic molecules and a Gd-based contrast ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-016-4552-7

    authors: Anemone A,Consolino L,Longo DL

    更新日期:2017-05-01 00:00:00

  • Perfusion CT in patients with advanced bronchial carcinomas: a novel chance for characterization and treatment monitoring?

    abstract::Advanced bronchial carcinomas by means of perfusion and peak enhancement using dynamic contrast-enhanced multislice CT are characterized. Twenty-four patients with advanced bronchial carcinoma were examined. During breathhold, after injection of a contrast-medium (CM), 25 scans were performed (1 scan/s) at a fixed tab...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-004-2288-2

    authors: Kiessling F,Boese J,Corvinus C,Ederle JR,Zuna I,Schoenberg SO,Brix G,Schmähl A,Tuengerthal S,Herth F,Kauczor HU,Essig M

    更新日期:2004-07-01 00:00:00

  • Deep learning analysis of left ventricular myocardium in CT angiographic intermediate-degree coronary stenosis improves the diagnostic accuracy for identification of functionally significant stenosis.

    abstract:OBJECTIVES:To evaluate the added value of deep learning (DL) analysis of the left ventricular myocardium (LVM) in resting coronary CT angiography (CCTA) over determination of coronary degree of stenosis (DS), for identification of patients with functionally significant coronary artery stenosis. METHODS:Patients who un...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5822-3

    authors: van Hamersvelt RW,Zreik M,Voskuil M,Viergever MA,Išgum I,Leiner T

    更新日期:2019-05-01 00:00:00

  • Reproducibility of linear tumor measurements using PACS: comparison of caliper method with edge-tracing method.

    abstract::The aim of this study was to evaluate inter- and intra-observer reproducibility when making electronic caliper linear tumor measurements on picture archiving and communications systems (PACS) and compare them with linear measurements obtained from circumferential tracing of tumor perimeter. Three radiologists measured...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-003-2027-0

    authors: Monsky WL,Raptopoulos V,Keogan MT,Doty D,Kamel I,Yam CS,Ransil BJ

    更新日期:2004-03-01 00:00:00

  • Scan and contrast administration principles of MDCT.

    abstract::Because of its fast scan speed, multi-detector row CT (MDCT) imposes a challenge to optimization of contrast enhancement and scan timing. However, when this challenge is overcome with the use of precisely designed protocols, MDCT provides us with an opportunity to use contrast medium more efficiently and flexibly than...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s10406-005-0165-y

    authors: Bae KT,Heiken JP

    更新日期:2005-12-01 00:00:00

  • Development and validation of a quantitative method for estimation of the urate burden in patients with gouty arthritis using dual-energy computed tomography.

    abstract:OBJECTIVES:To develop a method that allows approximating the mass of monosodium uric acid (MSU) in a gouty tophus using phantom measurements and including tophus density into the calculation of the dual-energy computed tomography (DECT) tophus volumetry. METHODS:We prepared specimens of different concentrations of MSU...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-019-06350-1

    authors: Kotlyarov M,Hermann KGA,Mews J,Hamm B,Diekhoff T

    更新日期:2020-01-01 00:00:00

  • Inter-sonographer reproducibility of quantitative ultrasound outcomes and shear wave speed measured in the right lobe of the liver in adults with known or suspected non-alcoholic fatty liver disease.

    abstract:OBJECTIVES:To assess inter-sonographer reproducibility of ultrasound attenuation coefficient (AC), backscatter coefficient (BSC) and shear wave speed (SWS) in adults with known/suspected non-alcoholic fatty liver disease (NAFLD). METHODS:The institutional review board approved this HIPAA-compliant prospective study; i...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5541-9

    authors: Han A,Labyed Y,Sy EZ,Boehringer AS,Andre MP,Erdman JW Jr,Loomba R,Sirlin CB,O'Brien WD Jr

    更新日期:2018-12-01 00:00:00

  • Nomogram including pretherapeutic parameters for prediction of survival after SIRT of hepatic metastases from colorectal cancer.

    abstract:OBJECTIVES:Pre-therapeutic prediction of outcome is important for clinicians and patients in determining whether selective internal radiation therapy (SIRT) is indicated for hepatic metastases of colorectal cancer (CRC). METHODS:Pre-therapeutic characteristics of 100 patients with colorectal liver metastases (CRLM) tr...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-015-3658-7

    authors: Fendler WP,Ilhan H,Paprottka PM,Jakobs TF,Heinemann V,Bartenstein P,Khalaf F,Ezziddin S,Hacker M,Haug AR

    更新日期:2015-09-01 00:00:00

  • Subtraction CT angiography improves evaluation of significant coronary artery disease in patients with severe calcifications or stents-the C-Sub 320 multicenter trial.

    abstract:OBJECTIVES:Diagnostic accuracy of conventional coronary CT angiography (CCTAconv) may be compromised by blooming artifacts from calcifications or stents. Blooming artifacts may be reduced by subtraction coronary CT angiography (CCTAsub) in which non-contrast and contrast CT data sets are subtracted digitally. We tested...

    journal_title:European radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00330-018-5418-y

    authors: Fuchs A,Kühl JT,Chen MY,Viladés Medel D,Alomar X,Shanbhag SM,Helqvist S,Kofoed KF

    更新日期:2018-10-01 00:00:00

  • The changed preliminary report: a repeatedly missed paediatric tibial tumour.

    abstract::This report describes a malpractice case involving a delayed diagnosis of a malignant bone tumour in the proximal tibia in a 10-year-old child. This was caused by a combination of factors. The final report on the first examination failed to reach the patient files, and two subsequent X-ray exams failed to diagnose the...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300051021

    authors: Finnbogason T,Ringertz HG

    更新日期:2000-01-01 00:00:00