Abstract：
BACKGROUND:Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. METHODS:From the prospective Danish cohort 'Diet, Cancer and Health', 23 864 postmenopausal women enrolled during 1993-1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. RESULTS:The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06-1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01-1.17) and 1.14 (95% CI=1.04-1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). CONCLUSION:Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height.
journal_name
Br J Cancerjournal_title
British journal of cancerauthors
Mellemkjær L,Christensen J,Frederiksen K,Baker JL,Olsen A,Sørensen TI,Tjønneland Adoi
10.1038/bjc.2012.244subject
Has Abstractpub_date
2012-06-26 00:00:00pages
165-8issue
1eissn
0007-0920issn
1532-1827pii
bjc2012244journal_volume
107pub_type
杂志文章abstract：:MDM2 is an oncoprotein that inhibits p53 tumour-suppressor protein. Amplification of the MDM2 gene and overexpression of its protein have been observed in some human malignancies, and these abnormalities have a role in tumorigenesis through inactivation of p53 function. To determine the clinicopathological and prognos...
journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1997.221
更新日期：1997-01-01 00:00:00
abstract：:Cellular DNA was analysed by flow cytometry in fine needles aspirates (FNA) from both benign and malignant breast lesions in order to determine the feasibility of flow cytometric analysis. In 22 of 26 (84%) benign and 69 of 74 (93%) malignant aspirates, sufficient cells were present to produce good quality DNA histogr...
journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1987.259
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journal_title：British journal of cancer
pub_type： 社论
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更新日期：2021-01-01 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1980.174
更新日期：1980-06-01 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.2016.98
更新日期：2016-05-24 00:00:00
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pub_type： 杂志文章
doi：10.1038/sj.bjc.6604315
更新日期：2008-04-22 00:00:00
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pub_type： 杂志文章
doi：10.1038/sj.bjc.6604749
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pub_type： 杂志文章
doi：10.1038/sj.bjc.6602093
更新日期：2004-09-13 00:00:00
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pub_type： 杂志文章
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更新日期：2016-07-26 00:00:00
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pub_type： 杂志文章
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更新日期：1979-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：2014-04-29 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1982.168
更新日期：1982-07-01 00:00:00
abstract：:Two hundred and twenty-two patients with advanced breast cancer were randomised in two separate trials of similar design to either concomitant combination treatment or sequential use of the same drugs given as single agents changed only at disease progression. Both trials used cyclophosphamide, methotrexate, 5-fluorou...
journal_title：British journal of cancer
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1989-02-01 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.2012.196
更新日期：2012-06-05 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1998.238
更新日期：1998-05-01 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1995.433
更新日期：1995-10-01 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1997.605
更新日期：1997-01-01 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1986.224
更新日期：1986-10-01 00:00:00
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pub_type： 杂志文章
doi：10.1038/bjc.1979.173
更新日期：1979-08-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1038/bjc.2014.65
更新日期：2014-04-02 00:00:00
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pub_type： 杂志文章
doi：10.1038/s41416-018-0199-2
更新日期：2019-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-12-10 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
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更新日期：1995-10-01 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1988.97
更新日期：1988-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1038/sj.bjc.6601340
更新日期：2003-11-03 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/sj.bjc.6603473
更新日期：2006-12-18 00:00:00
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journal_title：British journal of cancer
pub_type： 杂志文章
doi：10.1038/bjc.1993.48
更新日期：1993-02-01 00:00:00
